6 results about "Naphthalocyanine" patented technology

The application discloses a naphthalene phthalocyanine copper liposome and a construction method and application thereof, and belongs to the technical field of liposome preparations. The naphthalene phthalocyanine copper liposome can improve the problems of poor water solubility and insufficient stability of existing sonosensitizers by wrapping naphthalene phthalocyanine copper and catalase in the liposome. Meanwhile, the naphthalene phthalocyanine copper liposome has the function of catalyzing the production of O2 by excessive H2O2 in the microenvironment of brain glioma to supply the continuous production of ROS in the sonodynamic therapy (SDT), enhances the sonodynamic performance, improves the treatment effect of brain glioma, has the advantages of good biological safety, low immunogenicity and long circulation in the body, can effectively penetrate the blood-brain barrier and be delivered to the tumor site, solves the problems that drugs are difficult to penetrate the blood-brain barrier and cannot reach an effective concentration in the traditional treatment method of brain glioma, and provides a new strategy for the treatment of brain glioma.

The invention discloses a naphthalocyanine nano-liposome as well as preparation and optical diagnosis and treatment application thereof. The naphthalocyanine nano-liposome contains naphthalocyanine, dipalmitoyl phosphatidylcholine, molecular modified phospholipid polyethylene glycol with or without a cancer cell active targeting function, and cholesteryl hemisuccinate. The invention also discloses a preparation method of the naphthalocyanine nano-liposome, which comprises the step of preparing the liposome with or without the cancer cell active targeting function from the dipalmitoyl phosphatidylcholine, the molecule modified phospholipid polyethylene glycol with or without the cancer cell active targeting function and the cholesteryl hemisuccinate. And mixing the liposome with naphthalocyanine to obtain the naphthalocyanine nano-liposome. The naphthalocyanine nano-liposome can be applied to photoacoustic detection or imaging, photodynamic therapy, photothermal therapy and photodynamic and photothermal combined therapy of cancer cells or tumor tissues, and has remarkable application value.

The inventive technology is directed to novel photoacoustic endoskeletal droplet compositions and methods of making the same. Specifically, the naphthalocyanine dye-loaded endoskeletal droplets having a solid hydrocarbon core surrounded by a fluorocarbon liquid, which can further be applied to photoacoustic imaging and sensing, as well as photothermal therapy.

The present disclosure relates to a modulator material layer comprising a polymer matrix formed of a plurality of cross-linked polymer molecules and a plurality of liquid droplets of liquid crystal within the polymer matrix. A planar macrocycle dye is dispersed within the plurality of liquid droplets of liquid crystal. The planar macrocycle dye can comprise one or more of a phthalocyanine, a porphyrin, a naphthalocyanine, a metallophthalocyanine, a metalloporphyrin, or a metallo-naphthalocyanine.

The invention discloses an imide metal naphthyanine derivative as well as preparation and photovoltaic application thereof, and belongs to the field of perovskite solar photovoltaics. The metal naphthyanine derivative forms a larger pi conjugated system, and the pi-pi interaction between molecules can be enhanced by the extension of pi conjugation, so that the charge transfer capability is favorably improved. According to the Lewis acid-alkali theory, molecules containing electron-donating atoms such as nitrogen and oxygen can be used as a passivator to reduce defects in perovskite. According to the invention, an imide group with multiple coordination sites is introduced to the periphery of naphthyanine, and the obtained derivative is used as a passivator to be added into a perovskite thin film in a bulk phase doping manner, so that not only can non-coordinated ions (such as Pb < 2 + >) be efficiently passivated, but also the perovskite crystallization process can be regulated and controlled. Finally, the method is beneficial for forming a perovskite active layer with better crystallinity, larger grain size and more uniform morphology, and higher photoelectric conversion efficiency is obtained.

The invention discloses a copper naphthalocyanine liposome as well as a construction method and application thereof, and belongs to the technical field of liposome preparations. According to the copper naphthalocyanine liposome disclosed by the invention, the copper naphthalocyanine and the catalase are wrapped in the liposome, so that the problems of poor water solubility, insufficient stability and the like of an existing sound-sensitive agent can be improved; meanwhile, the nanomaterial has the effect of catalyzing excessive H2O2 in a brain glioma microenvironment to generate O2 to supply the O2 to a sonodynamic therapy (SDT) to continuously generate ROS, the sonodynamic performance of the nanomaterial is enhanced, the treatment effect of the brain glioma is improved, the nanomaterial has the advantages of good biological safety, low immunogenicity and in-vivo long circularity, and the nanomaterial can effectively penetrate through a blood brain barrier and is delivered to a tumor site, so that the nanomaterial has a good application prospect. The problems that in a traditional brain glioma treatment method, medicine cannot penetrate through the blood brain barrier easily and cannot reach the effective concentration are solved, and a new strategy is provided for treatment of brain glioma.