30 results about "Atrophic Vaginitis" patented technology

The present invention provides novel pharmaceutical compositions containing triphenylethylene derivative compounds, and methods of using the composition for treatment of symptoms associated with atrophic vaginitis. The pharmaceutical compositions are prepared for the vaginal administration of triphenylethylene derivative compounds in single or combination therapies. Preferably, the triphenylethylene derivative is tamoxifen.

The invention discloses a pharmaceutical composition for treating atrophic vaginitis and a preparation method thereof, which aim at solving the problem of treating atrophic vaginitis. The pharmaceutical composition is characterized by being prepared from the following active ingredients: cortex erythrina, smallflower bracketplant herb, tetrapanaxpapyrifer, Tianmu mountain magnolia immature flower, herba taxilli, radix ranunculi ternate, coking malt, scorch-fried medicated leaven, radix ephedrae, spina gleditsiae, peach gum, and cassia twig. Proved by clinical experiments, the drug for treating atrophic vaginitis has the characteristics of good curative effect and higher safety, thus being worth of clinical application and popularization.

The subject of the invention is compositions for vaginal use containing lupulus (Humulus lupulus) and an excipient base suitable for application in the vaginal and/or vulvar region, for the treatment of vaginal dryness (atrophic vaginitis) and of the disorders correlated thereto, pruritus, burning sensation, dryness, dyspareunia; they are also particularly useful for delaying and attenuating the changes in the physiological trophism of the vulvar and vaginal tissue and mucosa.

The invention discloses a preparation method of powder for treating atrophic vaginitis, aiming at solving the problem in treating atrophic vaginitis. The preparation method is characterized by comprising the following steps of: (1) carrying out reduced pressure distillation on crude powder of himalayan coralbean bark, ternate buttercup root and ephedra root and extracting volatile oil; (2) carrying out reduced pressure boiling on the volatile oil to obtain a filtrate; (3) boiling Trikeraia hookeri, Magnolia amoena, parasitic loranthus, coked malt, coked medicated leaven, spina gleditsiae, peach gum, cassia twig and the medicinal filtrate obtained in the step (1) so as to obtain a filtrate for later use; (4) combining the filtrates in the steps (2) and (3), carrying out reduced pressure concentration so as to obtain a dry extract, and crushing the dry extract to obtain dry extract powder; (5) ejecting the volatile oil obtained in the step (1) into the dry extract powder obtained in the step (4), uniformly mixing, screening in a sieve of 100 meshes and sub-packaging so as to obtain the powder. Clinical trial shows that the powder has the characteristics of being good in effect on treating atrophic vaginitis and high in security, and is worthy of clinical application and popularization.

Methods of treating disorders with cholinergic agonists for example, muscarinic receptor agonists such as pilocarpine and cevimeline are provided. In particular, methods of treating and/or preventing interstitial cystitis, yeast infections, urinary tract infections, atrophic vaginitis, vaginal dryness, and sexual dysfunction associated with vaginal dryness by administering a cholinergic agonist to the subject suffering from the disorders are provided. In addition, intra-vaginal administration of cholinergic agonists such as muscarinic receptor agonists to patients suffering from interstitial cystitis, vaginal dryness, and sexual dysfunction associated with vaginal dryness is also provided.

The present invention provides novel pharmaceutical compositions containing triphenylethylene derivative compounds, and methods of using the composition for treatment of symptoms associated with atrophic vaginitis. The pharmaceutical compositions are prepared for the vaginal administration of triphenylethylene derivative compounds in single or combination therapies. Preferably, the triphenylethylene derivative is tamoxifen.

The invention belongs to the technical field of medicines and particularly relates to heat-clearing and yin-nourishing rice bran oil as well as a preparation method and application thereof. The heat-clearing and yin-nourishing rice bran oil comprises the following components by weight: 40ml-60ml of rice bran oil, 80mg-120mg of vitamin C, 80mg-120mg of sophocarpidine, 130mg-170mg of a radix saposhnikoviae extract, 180mg-220mg of a lily extract and 80mg-120mg of sodium hyaluronate. The heat-clearing and yin-nourishing rice bran oil is helpful for treating atrophic vaginitis and has the characteristics of high efficiency and low relapse rate.

A Chinese medicine in the form of suppository for treating atrophic vaginitis is prepared from 8 Chinese-medicinal materials including epimedium, red peony root, liquorice root, rhubarb, etc. Its preparing process and quality control method are also disclosed.

The invention relates to the field of traditional Chinese medicines and particularly provides application of a traditional Chinese medicinal composition in preparing drugs for preventing and/or treating atrophic vaginitis. The traditional Chinese medicinal composition provided by the invention is prepared from the following raw materials: rhizoma alismatis, semen plantaginis, herba patriniae, floslonicerae, cortex moutan, herba hedyotidis diffusae, radix paeoniae rubra, agrimonia pilosa, rhizoma coptidis and cortex phellodendri. The traditional Chinese medicinal composition can be used for preparing drugs for preventing and/or treating the atrophic vaginitis and has obvious curative effects. The traditional Chinese medicinal composition has significantly improvement on symptoms of increased pH value of vagina, decrease of estrogen in blood and urine, reduction of microecological diversity, reduction of bacterial gene abundance and the like; the probability that a body is suffered fromthe atrophic vaginitis can be effectively prevented; meanwhile, the treatment effect on the atrophic vaginitis is also obvious, the blank that the atrophic vaginitis especially senile vaginitis cannot be effectively treated is filled up and the abuse of antibiotics is avoided. The components of the traditional Chinese medicinal composition are all Chinese herbal medicines and can be repeatedly used for a long time.

The DHEA bioadhesive controlled release gel includes DHEA mixed in a polymeric gel for the purpose of treating atrophic vaginitis, vaginal dryness, dyspareunia, itching, burning, irritation, increase in pH and decreased vaginal flora. The gel adheres to vaginal tissue and protects the DHEA from systemic absorption, which prevents leakage, loss of DHEA, and elevated levels of systemic DHEA. The gel is configured to slowly erode over time so as to deliver a predetermined dose of DHEA to vaginal tissue and thereby promote local intracellular conversion to estrogens, androgens and progesterone so that normal levels of fluid in the vagina is produced. The gel also acts as a moisturizer. An adjustable applicator may also be provided to insure proper placement and dose of the DHEA.