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184 results about "Reduced fat" patented technology

Instant sugar-controlling fat-reducing solid milk tea and preparation method thereof

The invention relates to the technical field of solid beverage food preparation, and discloses instant sugar-controlling and fat-reducing solid milk tea and a preparation method thereof. The formula of the instant solid milk tea capable of controlling sugar and reducing fat comprises the following raw material components in parts by mass: 2-4 parts of tea powder, 10-30 parts of milk powder, 1.8-2.5 parts of freeze-dried ginger powder, 8-15 parts of coconut oil powder, 6-8 parts of linseed diglyceride oil powder, 3-5 parts of stevioside powder and 2-4 parts of freeze-dried fruit powder. The instant sugar-controlling and fat-reducing solid milk tea provided by the invention is strong in solubility, can be quickly dissolved at low temperature without precipitation, is rich in nutrition, savoury and mellow in taste, smooth, fine and smooth without granular sensation and low in calorie, can accelerate fat consumption of an organism and soften blood vessels after being drunk, and has the characteristics of being instant, controlling sugar and reducing fat.
Owner:诺健康城国际健康管理(海南)有限公司

Sugar-controlling and fat-reducing composition for satiety as well as preparation method and application of sugar-controlling and fat-reducing composition

The invention discloses a satiety sugar-controlling fat-reducing composition and a preparation method and application thereof, the satiety sugar-controlling fat-reducing composition comprises hydrogel particles, a white kidney bean extract, a mulberry leaf extract, alpha-lipoic acid, L-carnitine, a lotus leaf extract, medium chain triglyceride, polyethylene glycol and sorbitol, and the composition is a tablet. The components are matched with one another to effectively adjust the leptin level, improve appetite, increase energy consumption, adjust the fat metabolism process, reduce fat accumulation, improve fat consumption, inhibit the activity of alpha-amylase, reduce the conversion of carbohydrates into fat, block heat and fat intake, promote gastrointestinal motility and enhance the immunity of the human body. The effects of remarkably reducing the fat content and the body weight are achieved.
Owner:SHANGHAI PANDA MEDICAL CO LTD +1

Zero-fat and zero-sucrose whipping cream and preparation method thereof

The present invention discloses a zero-fat zero-sucrose whipping cream, which comprises, by mass percentage, 3-5% compound protein powder, 20-30% maltodextrin, 1-3% compound stabilizer, 1-3% dietary fiber powder, 0-0.3% acidity regulator, and water added to 100%. The above raw materials are fully mixed to obtain a mixed powder; water is slowly added to the powder and stirred until completely mixed; a blender is used to whip for 6-8 minutes until soft peaks and a semi-solid state appear to obtain zero-fat zero-sucrose whipping cream. The zero-fat zero-sucrose whipping cream of the present invention has the characteristics of low calories and zero fat, and solves the problem of product quality degradation caused by reducing fat and sugar content in the prior art. The product is beneficial to human health, is easy to operate, has low production cost, and has high production efficiency. It also has a short whipping time, good whipping rate and stability, excellent decorating ability, and satisfactory taste and flavor.
Owner:JIANGNAN UNIV

Medicinal and edible food capable of reducing fat and weight and preparation method of medicinal and edible food

The invention discloses a fat-reducing and weight-reducing medicinal and edible food and a preparation method thereof, the composition comprises a lotus leaf extract, a Pu'er tea fermentation product, a hovenia dulcis thunb extract, konjac glucomannan, a pepper extract, fermented mulberry leaf powder, a prebiotic compound and oyster peptide, and the invention relates to the technical field of functional food. According to the fat-reducing and weight-reducing medicinal and edible food and the preparation method thereof, efficient fat reduction is realized through a four-dimensional synergistic effect (regulating lipid metabolism, inhibiting fat absorption, promoting energy consumption and improving intestinal flora).
Owner:SHANGHAI XUQING MEDICAL TECH CO LTD

Lithocarpus litseifolius low-GI biscuit with intestinal flora regulation function and preparation method thereof

The invention relates to the technical field of food processing, and discloses Lithocarpus litseifolius low-GI biscuits with an intestinal flora regulation function and a preparation method thereof.The preparation method comprises the following specific steps that Lithocarpus litseifolius tender leaves are spread, aired, roasted, rolled and dried and then made into Lithocarpus litseifolius ultra-fine powder with the specific particle size (300-900 meshes) through an ultra-fine crushing technology, and the Lithocarpus litseifolius ultra-fine powder with the specific particle size (300-900 meshes) is prepared into the Lithocarpus litseifolius low-GI biscuits. And then compounding the Lithocarpus litseifolius with wheat flour to prepare the Lithocarpus litseifolius biscuit. The Lithocarpus litseifolius low-GI biscuit prepared by the method is low in GI value, belongs to medium-GI food, overcomes the defects of high glycemic content and low dietary fiber content of traditional biscuits, is unique in taste and balanced in nutrition, can increase the content of short-chain fatty acid SCFAs in intestinal tracts, has the effects of regulating intestinal flora, maintaining blood sugar balance and reducing fat, and can be used for preparing the low-GI biscuit for the Lithocarpus litseifolius low-GI biscuit. The method has a wide prospect and a high market value.
Owner:SICHUAN AGRI UNIV

Rice bran fatty alkanol composition for reducing fat and losing weight and preparation method thereof

The invention provides a rice bran fatty alkanol composition for reducing fat and losing weight and a preparation method of the rice bran fatty alkanol composition. The rice bran fatty alkanol composition for reducing fat and losing weight is composed of rice bran fatty alkanol and soybean sterol, and the rice bran fatty alkanol accounts for 5-30% of the mass of the composition. By optimizing the fingerprint spectrum of rice bran fatty alkanol, the composition proportion of higher fatty alkanol is effectively improved, the lipid-lowering, weight-losing and liver-protecting effects can be effectively improved, the lipid-lowering, weight-losing and liver-protecting effects are greatly improved by matching with soybean sterol, and a tablet containing the composition is further developed. The obtained lipid-lowering weight-losing liver-protecting tablet is safe and free of side effects, and can be eaten for a long time to prevent obesity and fatty liver.
Owner:INST OF BIOLOGICAL RESOURCES JIANGXI ACAD OF SCI

Dietary fiber anti-obesity and lactone-reducing composition as well as preparation method and application thereof

The invention provides a dietary fiber anti-obesity and internal fat-reducing composition and a preparation method and application thereof, and the dietary fiber anti-obesity and internal fat-reducing composition comprises the following components in percentage by mass: a metabolic regulation formula which comprises 0.8-1.2% of mulberry leaf extract, 0.3-0.5% of potato extract, 0.2-0.4% of gamma-aminobutyric acid microcapsules and 4.0-6.0% of isomaltooligosacharide; the water management formula comprises 0.5 to 1.0 percent of opuntia ficus-indica powder and 0.2 to 0.4 percent of fructus gardeniae powder; the auxiliary regulation formula comprises the following components in percentage by weight: 2.0 to 4.0 percent of fructo-oligosaccharide, 0.05 to 0.15 percent of sucralose, 0.10 to 0.30 percent of xanthan gum and 0.05 to 0.15 percent of sodium citrate; and the nutrition fortification formula comprises 0.1-0.3% of taurine and 0.5-1.0% of a compound nutrition fortifier, and the compound nutrition fortifier contains vitamin B6 / B12, magnesium, iron and zinc. By constructing a fiber barrier-enzymolysis network-targeted metabolism three-in-one system, accurate reduction and control of visceral fat are achieved, fat oxidation combustion can be promoted, fat decomposition can be accelerated, fat accumulation can be reduced, and the method can be used for preparation of liquid beverages, preparation of powdery electuary and preparation of far infrared bagged powder solid beverages and has good application prospects. And the application scenarios are greatly increased.
Owner:ZHONGJIAN GUOKANG (GUANGDONG) HEALTH TECH CO LTD

Method for simulating traditional mayonnaise through pure fruits and vegetables

The invention provides a method for simulating traditional mayonnaise through pure fruits and vegetables, and relates to the technical field of processing of novel nutritional plant-based condiments. The chickpea milk and the soybean milk are utilized to form a double-soybean lactation system, starch, protein, pectin and the like in the pure fruit and vegetable paste are used for replacing natural fat to simulate traditional mayonnaise, compared with the traditional mayonnaise, the fat content is remarkably reduced, no remarkable difference exists in appearance, and texture characteristics such as viscosity and chewiness are improved to some extent; rheological characteristic parameters such as shear stress and elastic modulus are increased, the system network structure is enhanced, and the emulsion stability is enhanced; the pure fruit and vegetable paste is used as a fat substitute, so that the fat can be remarkably reduced, the protein, dietary fiber and ash content are remarkably improved, and the nutritional value of the product is improved; the pure fruit and vegetable fat-reducing vegetarian diet sauce prepared by the method disclosed by the invention meets the current consumption demands of consumers on nutrition, health and nature, and has a good market prospect.
Owner:ANHUI GRAIN ENG VOCATIONAL COLLEGE

Lipase inhibitor with specific structure as well as preparation method and application of lipase inhibitor

The invention belongs to the technical field of natural medicines, and particularly discloses a lipase inhibitor with a specific structure as well as a preparation method and application thereof, the inhibitor is derived from grape leaves and contains C6-C3-C6, 1, 2-benzopyrone, diphenyl ethylene and a phenolic hydroxyl structure, and the lipase inhibitor is a lipase inhibitor with a specific structure. Comprising the following components in percentage by mass: 72.1 to 97.5 percent of flavonoids, 2.5 to 5.1 percent of coumarins, 2.0 to 3.2 percent of stilbenes and 5.1 to 8.3 percent of phenolic acids. According to the lipase inhibitor with the specific structure as well as the preparation method and the application of the lipase inhibitor, the inhibitor can inhibit secretion of lipase, prevent fat from being decomposed into absorbable free fatty acid and monoacylglycerol, and reduce fat absorption; the total cholesterol and the low-density lipoprotein cholesterol are reduced, the blood fat level is improved, and the composition can be applied to preparation of health-care products, functional foods, sports nutritious foods and formula foods for special medical purposes.
Owner:OCEAN UNIV OF CHINA

An oral liquid for reducing fat and promoting metabolism and its preparation process

The present invention provides an oral liquid for reducing fat and promoting metabolism and its preparation process, belonging to the technical field of oral liquid preparation; the preparation process includes the following steps: preparation of cistanche juice; preparation of compound fruit vinegar juice; preparation of oligosaccharides from tiger nut meal; preparation of compound concentrated juice of prune and noni fruit; preparation of oral liquid for reducing fat and promoting metabolism. The present invention inhibits the activity of fat synthase through compound fruit vinegar juice to reduce fat synthesis; oligosaccharides from tiger nut meal promote the growth and reproduction of beneficial bacteria such as Bifidobacterium and Lactobacillus to assist in reducing fat, and the compounding of prune and noni fruit exerts efforts simultaneously from two aspects of inhibiting fat synthesis and promoting fat decomposition, more effectively reducing the accumulation of body fat, fundamentally solving the problem of fat accumulation, and effectively achieving the effect of reducing fat and promoting metabolism through the synergistic effect of multiple components from multiple angles.
Owner:SHANDONG LONGBEI BIOTECHNOLOGY CO LTD +1

Ganoderma lucidum polysaccharide as well as extraction method and application thereof

The invention belongs to the technical field of traditional Chinese medicine research, and particularly relates to ganoderma lucidum polysaccharide and an extraction method and application thereof. The structural formula of the ganoderan is shown as a formula I in the specification. The ganoderan extracted by the invention can repair intestinal barriers by promoting the growth of beneficial intestinal bacteria, alleviate liver inflammation by targeting LPS / TLR4 / NF-kappa B / MAPK signal pathways, and reduce fat accumulation, thereby effectively alleviating the non-alcoholic fatty liver disease; and # imgabs0 #.
Owner:XINXIANG MEDICAL UNIV

Composition with effects of losing weight and reducing blood fat and preparation method thereof

The invention discloses a composition with effects of losing weight and reducing blood fat. Every 100g of the composition comprises the following components and contents: (1) 10-30mg of adiponectin functional fragments; (2) 5 to 15 mg of PCSK9 inhibitory peptide; (3) 1-5 g of a radix puerariae extract; (4) 1-3 g of garcinia cambogia extract; (5) 0.5-2 g of a green coffee bean extract; (6) 1 to 3g of microencapsulated fish oil; (7) 0.5 to 1g of chitosan; and 5 to 10 g of erythritol. Through the synergistic effect of various bioactive components, the composition can effectively reduce fat accumulation and reduce the blood fat level, and meanwhile has good taste and use convenience. The composition disclosed by the invention provides an innovative solution for losing weight and reducing blood fat, and has potential clinical and commercial application values.
Owner:GUANGDONG GUANYIN PHARMACEUTICAL BIOTECHNOLOGY DEVELOPMENT CO LTD

Durnella, extracellular polysaccharide produced by same and application of extracellular polysaccharide

The invention discloses a Dunella strain, polysaccharide produced by the Dunella strain and application of the Dunella strain. The preservation number of the Duronella G3 is CCTCC (China Center For Type Culture Collection) NO: M 2024137, and the exopolysaccharide TDG3 produced by the Duronella G3 is used as a TLR4 / DC-SIGN dual receptor agonist and has the effect of remarkably reducing body weight. The exopolysaccharide TDG3 disclosed by the invention can obviously reduce the appetite of mice, reduce the food intake, reduce the body weight and reduce the content of adipose tissues, can also relieve or prevent liver fatty degeneration caused by obesity, is safe and non-toxic, is suitable for preparing the medicines for reducing fat and losing weight, and has a relatively good clinical application value and a wide application prospect.
Owner:NANJING SOUTHERN ELEMENT BIOTECHNOLOGY CO LTD

Nutrient solution containing chlorella as well as preparation method, application and use method of nutrient solution

The invention relates to the technical field of livestock feed, in particular to a nutrient solution containing chlorella as well as a preparation method, application and a use method of the nutrient solution. The nutrient solution comprises a chlorella product, a nutrition additive and a rumen fermentation regulator, and the ratio of the chlorella product to the nutrition additive to the rumen fermentation regulator is 100 mL: (5-10) g: (20-35) g. The chlorella product is prepared from chlorella enzymatic hydrolysate and lactobacillus plantarum fermentation liquor. The nutrition additive comprises vitamins and trace elements; the rumen fermentation regulator comprises sodium bicarbonate and chitosan. The invention also provides an application of the nutrient solution in barn-feeding beef cattle breeding and a preparation and use method of the nutrient solution. The prepared nutrient solution containing chlorella not only can improve the immunity of barn-feeding beef cattle, but also can reduce fat deposition of the beef cattle and improve the beef quality.
Owner:ZHONGKE YUNPU (INNER MONGOLIA) GENE BIOTECHNOLOGY CO LTD

Application of caffeic acid phenethyl ester high-fat feed in improvement of overwintering health condition of grass carp and reduction of fat loss rate

The invention discloses an application of a caffeic acid phenethyl ester high-fat feed in improving the overwintering health condition of grass carp and reducing the fat loss rate, and belongs to the technical field of aquaculture. According to the method, the caffeic acid phenethyl ester is added into the high-fat feed, and the grass carp is fed within 40 days before overwintering. Experiments prove that according to the strategy, fat cells of the grass carps can be proliferated before overwintering, so that the energy utilization mode of the grass carps in the overwintering period is changed, the health condition of the grass carps in the overwintering period is improved, and finally the weight loss of the grass carps is reduced. New opinions and theoretical bases are provided for improving the health condition of the cultured fishes in the overwintering period and reducing fat loss of the cultured fishes in the overwintering period.
Owner:NORTHWEST A & F UNIV

Composition for dissolving turbidity and reducing lipid and preparation method thereof

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a turbidity-dissolving and lipid-lowering composition and a preparation method thereof.The composition comprises 80-130 parts of polygonum cuspidatum, 50-90 parts of fried semen cassiae, 100-140 parts of hawthorn, 50-90 parts of rhizoma alismatis, 10-60 parts of rhizoma atractylodis macrocephalae fried with bran and 50-90 parts of rhizoma wenyujin concisum. The composition disclosed by the invention has the effects of eliminating phlegm, dissolving turbidity, promoting blood circulation to remove blood stasis, invigorating stomach and promoting diuresis, can be used for treating hyperlipidemia, hyperviscosity and arteriosclerotic cardia-cerebrovascular diseases, and has a very good application prospect.
Owner:THE FIRST AFFILIATED HOSPITAL OF TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Methods and compositions for reducing body weight in mammals

PendingUS20250345379A1Organic active ingredientsPeptide/protein ingredientsCarbohydrate absorptionPhysiology
Methods and compositions promote weight loss in mammals, such as in humans and / or animals, such as, for example, pets. Specifically, the methods and compositions herein promote weight loss due to the production of appetite-suppressing gut hormones, increased metabolism, reduced fat and carbohydrate absorption, and reduced fat deposition through the synergistic combination of fibers and botanical extracts. Food products comprising the compositions herein provide a natural and effective means of controlling appetite and managing weight.
Owner:LAFOND DAVID +1

Compound nutrition preparation for reducing fat and increasing muscle and preparation method thereof

The invention discloses a compound nutritional preparation for reducing fat and increasing muscle and a preparation method thereof, and relates to the field of weight-losing foods. The compound nutrition preparation comprises a fat-reducing and muscle-building composition. The composition comprises the following components: soybean protein isolate, flaxseed powder, whey protein, pumpkin powder, isomaltooligosaccharide, Chinese yam powder, medium-chain fatty acid, calcium beta-hydroxy-beta-methyl butyrate, sunflower seed powder, wheat germ powder, L-glutamine, casein, psyllium husk, konjaku flour, wheat oligopeptide, vitamin E, vitamin D and stevioside. The compound nutritional preparation provided by the invention not only can significantly reduce the weight and the fat content of the whole body, but also can increase the skeletal muscle amount of the whole body, is safe and effective, and has no adverse reaction.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Health-care medicine-food homologous traditional Chinese medicine formula for removing food retention, clearing damp and reducing fat

The invention relates to the technical field of traditional Chinese medicines, in particular to a food retention removing, dampness eliminating and fat reducing health-care medicine-food homologous traditional Chinese medicine formula. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-60g of raw hawthorn or extract, 5-60g of dark malt or extract, 5-60g of pericarpium citri reticulatae or extract, 5-60g of poria cocos or extract, 5-60g of rhizoma alismatis or extract, 5-60g of scorched medicated leaven or extract, 5-60g of selfheal or extract, 5-60g of fried semen pharbitidis or extract, 5-60g of phaseolus calcaratus or extract and 5-60g of semen raphani or extract. The preparation method comprises the following steps: S1, raw material pretreatment, S2, raw material preparation, S3, raw material preparation, S4, raw material preparation, S5, raw material preparation, S5, raw material preparation, S6, raw material preparation, S6, raw material preparation, S6, raw material preparation, and S6, raw material preparation. S2, crushing; s3, mixing; the preparation has the advantages that food retention in the body can be effectively eliminated, dampness is removed, body metabolism is adjusted, the purpose of reducing fat is achieved, the used raw materials are all traditional Chinese medicines with homology of medicine and food, safety and reliability are achieved, the preparation method is simple and diverse, and the cost is low.
Owner:BEIJING BAOFUTANG INST OF TRADITIONAL CHINESE MEDICINE

Nanometer antibody NB21 targeting LGR4 and application of nanometer antibody NB21 in anti-obesity treatment

The invention provides a nano antibody NB21 targeting LGR4 and an application of the nano antibody NB21 in anti-obesity treatment. Specifically, the invention discloses a nano antibody NB21 targeting LGR4 and a derivative protein thereof, a gene sequence for coding the nano antibody NB21 and the derivative protein thereof, and an expression vector and an expression system for producing the nano antibody NB21 and the derivative protein thereof. Besides, in-vitro and in-vivo experiments verify that the nano antibody NB21 for targeted blocking of the LGR4 has high affinity and high specificity, plays the biological functions of promoting heat production and reducing fat, and provides a new strategy for obesity treatment.
Owner:RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1

Compounds for modulating energy expenditure

The present disclosure relates to a method of preventing or treating a disease or disorder in a subject in need thereof, wherein administration of a composition of the present disclosure is effective to result in an increase of energy expenditure in the subject. The present disclosure provides a method of reducing fat mass and / or improving glycemic control in a subject in need thereof. The present disclosure provides a method of promoting weight loss and weight maintenance. The present disclosure provides a method of maintaining lean mass. Compositions for use in the methods include a compound of formula (I), (II), or (III), or pharmaceutically acceptable salts thereof, or in combination with a compound selected from the group consisting of an ACC2 inhibitor and an incretin mimetic.
Owner:ORSOBIO INC

Application of hyodeoxycholic acid in reducing animal fat deposition

ActiveCN115813936BOrganic active ingredientsMetabolism disorderEndogenous metabolismDisease
The present invention relates to the field of animal breeding technology, and in particular to the use of porcine deoxycholic acid in reducing animal fat deposition. The present invention uses UCP1 genetically modified pigs with a low-fat phenotype to conduct targeted metabolic analysis in feces, and discovers and identifies a pig intestinal endogenous metabolite that can reduce fat deposition, porcine deoxycholic acid, whose chemical formula is C 24 H 40 O4. The present invention finds that the content of swine deoxycholic acid can indicate the fat deposition ability of pigs, and oral administration of swine deoxycholic acid to mice can significantly reduce the fat deposition of mice. The swine deoxycholic acid provided by the present invention has the effect of reducing fat deposition, and can be developed as a feed additive for reducing pig fat deposition in the future. At the same time, it can be applied to the research and development of drugs for reducing human obesity, providing a scientific basis for the treatment of human obesity and other diseases.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Functional solid beverage capable of reducing fat, losing weight and conditioning five highs and preparation method of functional solid beverage

The invention discloses a functional solid beverage capable of reducing fat, losing weight and conditioning five highs. According to the functional solid beverage, dietary fibers such as fructo-oligosaccharide, inulin and the like are used for regulating intestinal flora, a white kidney bean extract is used for inhibiting the activity of alpha-amylase, L-carnitine is used for promoting fat transport, and medicinal and edible components such as ginseng, lotus leaves and the like are matched to realize multi-way metabolism regulation. The weight percentage of each component can be adjusted within a specified range so as to adapt to different physique requirements. Animal experiments prove that the total cholesterol (TC) of serum can be obviously reduced by 21.3-25.8% and the triglyceride (TG) can be obviously reduced by 28.9-34.2% after the traditional Chinese medicine is continuously taken for 4 weeks, and meanwhile, the insulin resistance index (HOMA-IR) can be improved to 16.5-20.3%.
Owner:GUANGZHOU SHANGMEI FUYUAN LIFE TECH GRP CO LTD

Traditional Chinese medicine substitutional tea granules capable of promoting digestion and reducing fat and preparation method of traditional Chinese medicine substitutional tea granules

The invention discloses traditional Chinese medicine substitutional tea granules for aiding digestion and reducing fat and a preparation method thereof, probiotic microcapsules, traditional Chinese medicine lipid nanoparticles and Tibetan tea active ingredients are combined, and the effects of improving digestion and reducing fat are achieved through a triple synergistic mechanism. The probiotic microcapsules are embedded with citrus fibers through the poria cocos extract and then are mixed with the Chinese yam thick soup for freeze-drying, so that the survival rate of probiotics and the intestinal colonization effect are remarkably improved. The rhizoma alismatis and semen cassiae extracts are encapsulated in lecithin / lauric acid / palmitic acid lipid nanoparticles, so that unpleasant odor is covered, slow release is realized, and the metabolic regulation effects of palmitic acid and lauric acid are coordinated. In addition, Tibetan tea is used as a compound substrate, traditional Chinese medicines such as codonopsis pilosula, hawthorn and poria cocos are fused, honey, coix seeds and Chinese yam are used as auxiliary materials for granulation, and medicinal material natural polysaccharide is used for replacing a chemical adhesive. The product has probiotic activity protection, traditional Chinese medicine slow release and tea fragrance palatability, and has remarkable synergistic advantages in the aspects of improving the digestion function and regulating body fat.
Owner:MINXI VOCATIONAL & TECHN COLLEGE +1

Use of polypeptide in preparation of drugs, foods, or health care products for treating obesity and comorbidities thereof

Disclosed is use of a polypeptide in the preparation of drugs, foods, or health care products for treating obesity and comorbidities thereof, which belongs to the technical field of biological medicines. The polypeptide is a human GPR15L polypeptide or a mouse GPR15L polypeptide and a polypeptide conjugate thereof. The treatment of obesity includes: reducing fat accumulation, promoting fat thermogenesis and catabolism, increasing energy consumption, and reducing body weight. The obesity comorbidities include: chronic inflammation, fatty liver, steatohepatitis, metabolic diseases, cardiovascular and cerebrovascular diseases, osteoarticular diseases, Alzheimer's disease, depression, tumors, and skin diseases. A novel mechanism of action reduces blood glucose and body weight, thereby effectively treating obesity and comorbidities thereof.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Lipid-lowering and weight-losing composition with homology of medicine and food as well as preparation method and application thereof

The invention discloses a lipid-lowering and weight-losing composition with homology of medicine and food as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compositions. The composition for reducing fat and losing weight comprises the following raw materials in parts by weight: 10-40 parts of lotus leaves, 20-50 parts of haws, 15-45 parts of poria cocos, 5-35 parts of dried orange peel, 60-130 parts of raspberries, 0-15 parts of fingered citron and 0-15 parts of kudzuvine roots. Compared with a model group, the fat-reducing and weight-losing composition disclosed by the invention has the advantages that the weight of a mouse can be reduced by 12%-15%, the serum total cholesterol level and the leptin level are reduced, the number of fat cells per unit area is increased, the liver adiposis symptom is obviously improved, the expression of heat production factors in epididymal fat and groin fat is up-regulated, and liver toxicity is avoided. The raw materials of the composition for reducing fat and losing weight are all traditional Chinese medicines with homology of medicine and food, so that the composition has no obvious damage to organisms and is safer; the fat-reducing and weight-losing composition can achieve a good weight-losing effect by compounding the raw materials.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Preparation method and application of 2, 5-diketopiperazine derivative

The invention discloses a preparation method and application of a 2, 5-diketopiperazine derivative, and belongs to the field of biological medicine. The preparation method comprises the following steps: by taking 1, 4-diacetyl piperazine-2, 5-diketone (II) as an initial raw material, firstly, carrying out condensation reaction on the initial raw material and isobutyraldehyde to prepare a key intermediate (III); meanwhile, 4-amino-1-butanol (IV) is converted into an intermediate (VI) through acylation and oxidation two-step reaction; and finally, carrying out condensation and elimination reaction on the intermediates (III) and VI to prepare the target compound (I). The preparation method provided by the invention has the advantages of reasonable route design, mild conditions and outstanding stereoselectivity. According to the method, on the basis of easily available raw materials, a product mainly comprising a Z configuration is efficiently constructed through a modular strategy and consistent mild base catalysis conditions. Experimental data show that the compound prepared by the invention can inhibit TG accumulation in nematode bodies and reduce nematode fat accumulation, and can be developed into efficient medicines for preventing and treating obesity.
Owner:OCEAN UNIV OF CHINA

Sugar-controlling and weight-losing functional food cooperatively conditioned by endogenous enzymes of processing raw materials and preparation method thereof

The invention relates to a sugar-controlling and weight-losing functional food cooperatively conditioned by endogenous enzymes of processing raw materials and a preparation method thereof, and belongs to the technical field of food. The raw materials comprise 6-10 parts of white kidney beans, 4-8 parts of lucid ganoderma, 20-40 parts of black-skin and green-kernel black beans, 3-6 parts of mung beans and 40-60 parts of wheat flour / rice flour. A dual biological activation process is adopted: white kidney beans are subjected to low-temperature enzymolysis by yeast powder and probiotic soybean enzymes (1%, 25-35 DEG C) for 2-4 hours to release an alpha-amylase inhibitor, and ganoderma lucidum is subjected to weak-base hydrolysis by sodium bicarbonate (1-3%) for 2-4 hours to activate a triterpenoid glycosidase inhibitor; and performing compound fermentation on the zymolyte and the alkaline hydrolysis product for 2-4 hours, and then adding a cereal base material to activate the endogenous enzyme activity. High fiber combination (more than 15%) is used for prolonging satiety and reducing fat absorption, resistant starch (heat is only 50% of saccharides) is used for inhibiting lipid synthesis, and quadruple synergy (enzyme inhibition is more than 90% / resistant starch / low GI / high fiber) is combined, so that dual effects of postprandial blood sugar reduction and weight control are realized.
Owner:HANGZHOU GREEN SHANGJIA AGRICULTURAL SCIENCE & TECHNOLOGY SERVICE CO LTD

Dietary fiber composition capable of reducing calorie intake and slowing down digestion speed and preparation method of dietary fiber composition

The invention provides a dietary fiber composition capable of reducing calorie intake and slowing down digestion speed and a preparation method thereof, and belongs to the technical field of weight control. The feed additive is prepared from the following raw materials in parts by weight: 18-20 parts of sodium carboxymethyl cellulose, 1-2 parts of lecithin, 15-18 parts of modified konjac glucomannan, 4-8 parts of L-carnitine, 4-8 parts of a white kidney bean extract, 1-2 parts of chlorogenic acid and 3-5 parts of probiotics. The dietary fiber composition capable of reducing calorie intake and slowing down digestion speed, prepared by the invention, regulates fat metabolism in a targeted manner through multiple metabolism, reduces calorie intake, slows down digestion speed, improves glucose metabolism in a body, improves calorie consumption of the body, reduces fat hoarding, improves satiety, reduces food intake, prolongs the duration time of satiety, and has the efficacy of reducing calorie intake and slowing down digestion speed. Therefore, a good body weight control effect is achieved, and wide application prospects are achieved.
Owner:BEIJING XINGFU ENERGY HEALTH TECH CO LTD

A beverage of longan fruit vinegar

PendingCN122375698ABiotechnologyVitamin C
The present application provides a kind of Laumei fruit vinegar beverage, is by Laumei fruit, brewing rice vinegar, yellow granulated sugar, honey proportion (weight ratio is 10:40:5:2) mixed after soaking, add appropriate amount of purified water and be made into.The Laumei fruit is the plant that Hubei Wudang mountain is unique, has generating effect of Xitie, clearing spirit and lowering qi, is called as holy fruit in ancient times, Ming Dynasty emperor Zhu Di also lists Laumei as tribute to the court.Fresh Laumei fruit contains rich phosphorus, iron, calcium, vitamin C, carotene and other nutrients and seventeen kinds of amino acids necessary for human body, has the effect of helping digestion, phlegm, kidney, refreshing, invigorating blood, strengthening body, tranquilizing pain, reducing pressure and reducing fat, also has the health care effect of anti-inflammatory analgesic, eliminating fatigue, detoxification, enhancing immunity, etc.The present application not only improves the utilization value of Laumei fruit, but also greatly improves the nutritional and health care function of Laumei fruit vinegar, low cost, improves the economic benefit, and creates good social benefit.