207 results about "Glyceric acid" patented technology

The invention provides a non-naturally occurring microorganism having one or more gene disruptions, the one or more gene disruptions occurring in genes encoding an enzyme obligatory coupling 3-hydroxypropionic acid production to growth of the microorganism when the gene disruption reduces an activity of the enzyme, whereby the one or more gene disruptions confers stable growth-coupled production of 3-hydroxypropionic acid onto the non-naturally occurring microorganism. Also provided is a non-naturally occurring microorganism comprising a set of metabolic modifications obligatory coupling 3-hydroxypropionic acid production to growth of the microorganism, the set of metabolic modifications having disruption of one or more genes including: (a) the set of genes selected from: (1) adhE, ldhA, pta-ackA; (2) adhE, ldhA, frdABCD; (3) adhE, ldhA, frdABCD, ptsG; (4) adhE, ldhA, frdABCD, pntAB; (5) adhE, ldhA, fumA, fumB, fumC; (6) adhE, ldhA, fumA, fumB, fumC, pntAB; (7) pflAB, ldhA, or (8) adhE, ldhA, pgi in a microorganism utilizing an anaerobic β-alanine 3-HP precursor pathway; (b) the set of genes selected from: (1) tpi, zwf; (2) tpi, ybhE; (3) tpi, gnd; (4) fpb, gapA; (5) pgi, edd, or (6) pgi, eda in a microorganism utilizing an aerobic glycerol 3-HP precursor pathway; (c) the set of genes selected from: (1) eno; (2) yibO; (3) eno, atpH, or other atp subunit, or (4) yibO, atpH, or other atp subunit, in a microorganism utilizing a glycerate 3-HP precursor pathway, or an ortholog thereof, wherein the microorganism exhibits stable growth-coupled production of 3-hydroxypropionic acid. The disruptions can be complete gene disruptions and the non-naturally occurring organisms can include a variety of prokaryotic or eukaryotic microorganisms. A method of producing a non-naturally occurring microorganism having stable growth-coupled production of 3-hydroxypropionic acid is further provided. The method includes: (a) identifying in silico a set of metabolic modifications requiring 3-hydroxypropionic acid production during exponential growth, and (b) genetically modifying a microorganism to contain the set of metabolic modifications requiring 3-hydroxypropionic acid production.

The invention discloses a metabolism marker for screening and monitoring a colorectal cancer. The metabolism marker is beta-hydroxybutyrate, 5-hydroxytryptamine, lysophosphatidyl choline (C14:0), lysophosphatidyl choline (C16:1), alpha-ketobutyrate, fumaric acid, aspartic acid, 2-octene diacid, glycerin, glyceric acid, tryptophan, aconitate, citric acid, ornithine, glycerol monopalmitate, creatinine, methionine and citrulline. The invention also provides a kit with auxiliary functions of early diagnosis and prognosis monitoring on the colorectal cancer. The application of the micromolecule metabolism marker to monitoring of the colorectal cancer not only greatly improves the accuracy, but also has great guiding significance for development of a subsequent clinical application study.

The invention relates to chitosan gel for women. The chitosan gel for women is obtained by mixing chitosan with specific molecular weight and degree of deacetylation, glycerol, acidifier and purified water in a gelatinization manner and then sterilizing. The chitosan gel for women, provided by the invention, has good adhesive power, uniform colour and lustre and stability, and has the advantages of good curative effect, safety, natural property, good biocompatibility and the like when used for treating monilial vaginitis, bacterial vaginitis, mixed vaginitis, cervicitis, cervical erosion and the like of women. The invention also relates to a preparation method and medical application of the chitosan gel for women.

Described herein is a novel, cost effective, stable and recyclable catalyst composition i.e. A-B-OMS, wherein ‘A’ is selected from noble and transition metals; ‘B’ is selected from alkali or alkaline earth metals; and OMS is octahedral molecular sieve which includes synthetic todorokite (OMS-1) and cryptomelane (OMS-2); and characterization thereof. Further the invention provides base free green process for selective aerobic oxidation of 5-hydroxymethylfurfural (HMF) catalysed by said catalyst composition under optimized reaction conditions to obtain high yield of 2,5-furandicarboxylic acid (FDCA) in a shorter span of time. Invention also provides for selective oxidation of glucose to Gluconic Acid, furfural to furoic Acid and glycerol to Glyceric acid. Invention can also applicable for the selective oxidation of hexoses, pentoses, disaccharides to corresponding acids.

The invention relates to nicotine salt, electronic cigarette oil and a preparation method thereof. The nicotine salt comprises the following components by mass: 20-70 parts of organic acid and 5-70 parts of nicotine, wherein the organic acid is at least one selected from strawberry acid, glyceric acid and fumaric acid. The electronic cigarette oil comprises the nicotine salt, and has the advantages of comfortable throat feeling, moderate strength and comfortable taste.

The invention discloses an edible compound coating antistaling agent for drupes. The edible compound coating antistaling agent belongs to the field of fresh preservation and treatment of fruits and vegetables and is characterized in that chitosan and other auxiliaries are dissolved in a water solution prepared in an acetic acid solution with low concentration. According to the invention, glycerylmonostearate and Tween 80 are added in chitosan coating, thus the connecting strength of antibacterial components is enhanced and, the toughness and air permeability of the coating are improved; and meanwhile, other components in the fresh preservation agent, such as sodium ascorbate, sodium chloride, and the like, have greater bacterial resistance and fresh preservation effects. The edible compound agent, after being applied to coating the drupes, can form a layer of shiny transparent film on the surface of each drupe and achieves the functions of preserving water, reducing bacterial contamination, preventing the growth of microorganisms, resisting oxidation and inhibiting the fruit respiration. The edible compound agent can be widely applied in the storage and fresh preservation of the drupes and achieves greater fresh preservation effects than other methods. The edible compound agent is convenient to prepare and use, requires small equipment investment, occupies a small operation area, and is suitable for industrial batch production.

The invention provides a method for preparing glyceric acid in one step by directly adopting dioxygen catalytic oxidation, which takes glycerine as the raw material, under the condition of the presence of the oxygen and under the action of activated carbon or graphite loaded metallic catalyst, to prepare the glyceric acid in one step in a batch type. The active component of the catalyst is a single reactive metal of Pt, Cu, Fe, Ni, Cr, Zn, Ru, Re, Au, Ag, Mn, and Sn, or a double compound of the above metals or an alloyed bi-component. The method for preparing the glyceric acid ensures the conversion rate of the glycerine to be 70 to 92 percent, and the yield coefficient of the glycerine to be 40 to 66 percent. The method has the good advantages that the cost is low, the percentage yield is high, the performance of the catalyst is steady, the operation is simple, the separation is simple, and no environmental contamination occurs.

The invention discloses polyvinyl chloride synthetic leather for a luggage. The leather comprises a surface layer, a foaming layer, a bonding layer and fluffing cloth. The surface layer is slurry prepared from the following raw materials in parts by weight: 40-50 parts of SG-3 PVC (Polyvinyl Chloride) resin, 70-80 parts of SG-5 PVC resin, 30-35 parts of glycerol triacetate, 10-15 parts of epoxidized soybean oil, 20-25 parts of glycerol triglycerate, 5-6 parts of PVC color cream, 1-2 parts of bimercapto iso-octyl acetate di-n-octyl tin, 5-10 pats of zinc oxide and 5-10 parts of modified attapulgite. Through improvement of formula and process provided by the invention, the flexibility of the synthetic leather is enhanced, and the synthetic leather has a natural and comfortable handfeel similar to that of natural leather. The synthetic leather is not easy to damage or tear within 3-5 years, and suitable for use in lug gages.

A method of preventing or treating infection by a range of fungal pathogens in an animal or plant or stored plant product comprising administering an effective amount of a sugar acid, in particular mannonic acid, gluconic acid or galacturonic. The sugar acid can be delivered by a biocontrol that can manufacture the sugar acid. An exemplified biocontrol is Pseudomonas strain AN5, which is characterized by the capacity to convert aldose to sugar acid. Also disclosed are nucleotide sequences from enzymes in the Pseudomonas PQQ enzyme pathway which may be used to transform microorganisms and plants so that they produce sugar acids at levels sufficient to control the growth or viability of pathogens.

The invention discloses PET (polyethylene glycol terephthalate) fiber/ceramic fiber composite sound absorbing cotton, which is prepared from the following ingredients in parts by weight: 70 to 80 parts of PET fibers, 40 to 50 parts of ceramic fibers, 10 to 15 parts of emulsifying agents OP-4, 5 to 10 parts of peregal O-15, 80 to 100 parts of PP (propene polymer), 30 to 40 parts of SBR (styrene butadiene rubber), 15 to 20 parts of nanometer bauxite, 10 to 15 parts of modified kieselguhr, 2 to 3 parts of stearic acid, 5 to 8 parts of glycerol triglycerin acid ester, 4 to 6 parts of triphenyl phosphate, 2 to 3 parts of microcrystalline wax, 1 to 2 parts of vinyl (beta-methoxyethoxy) trisilane, 2 to 3 parts of zinc stearate, 1 to 2 parts of lead sulfate tribasic, 0.5 to 1.5 parts of anti-aging agents ODA (octyl decyl adipate) and 1 to 2 parts of antioxidants 168. The sound absorbing cotton prepared by the invention has the advantages that the appearance evenness is good, the thickness is uniform, the hand feeling is soft, the product bonding degree is good, the tensile performance is high, the sound absorbing performance is excellent, the flame retardant effect is good, and the like.

The present invention includes a group of novel compounds that are demonstrated to potently and selectively inhibit HIV integrase (IN) activity in vitro and to potently inhibit HIV replication in live, cultured cells at non-toxic concentrations. The novel compounds disclosed include 2,3-di(3,4-dihydroxy-dihydroxydihydrocinnamoyl)-L-tartaric acid, 2,3-di-(3,4-dihydroxybenzoyl)-L-tartaric acid, 2,3-di-(3,4-dihydroxyphenylacetyl)-L-tartaric acid, 2,3-di-(3,4,5-trihydroxybenzoyl-L-tartaric acid, 2,3-dicaffeoyldiamidopropionic acid, 1,2,-dicaffeoyl-L-glyceric acid, bis,-3,4-dicaffeoyldiamidobenzoic acid, di-3,4-dihydroxybenzylidene succinic acid, di-3,4-dihydrodihydroxybenzylidine succinic acid, 2,3-dicaffeoyl-L-serine, bis-dicaffeoyl-L-isoserine and 1,4-dicaffeoyl-L-lysine. Tests of integrase inhibitors with 2′,3′-dideoxycytidine, zidovudine and nelfinavir (protease inhibitor) indicated a potent synergy against reverse transcriptase inhibitor resistant virus. The potential benefit from the addition of integrase inhibitors to combination drug therapies is significant.

A polishing composition for a substrate to be used for a memory hard disk, which comprises the following components (a) to (d):(a) water,(b) at least one compound selected from the group consisting of a polyoxyethylene polyoxypropylene alkyl ether and a polyoxyethylene polyoxypropylene copolymer,(c) at least one compound selected from the group consisting of nitric acid, nitrous acid, sulfuric acid, hydrochloric acid, molybdic acid, sulfamic acid, glycine, glyceric acid, mandelic acid, malonic acid, ascorbic acid, glutamic acid, glyoxylic acid, malic acid, glycolic acid, lactic acid, gluconic acid, succinic acid, tartaric acid, maleic acid and citric acid, and their salts, and(d) at least one abrasive selected from the group consisting of aluminum oxide, silicon dioxide, cerium oxide, zirconium oxide, titanium oxide, silicon nitride and silicon carbide.

The invention relates to sterile cleansing solution for women. The cleansing solution is composed of chitosan with a specific molecular weight and deacetylation degree, chlorhexidine, glycerol, acidifier and purified water. The cleansing solution is applied in the environment with hundred-thousand-level cleanliness, the chitosan and the purified water are mixed to form suspension liquid, acidifier is added in the suspension liquid to adjust the pH value to be within the range from 3.8 to 5.8, and chitosan gel is obtained. The chlorhexidine is additionally taken and is dissolved in the glycerol and is added in the chitosan gel, the chitosan gel is evenly stirred, degasification is conducted, filling sealing is conducted and sterilization is conducted, wherein the acidifier is lactic acid or acetic acid or the mixture of hydrochloric acid and acetic acid, and Co-60 irradiation processing or high-temperature damp and hot sterilization is conducted during the sterilization process. The invention further relates to the manufacturing method of the cleansing solution for curing the gynecological disease and the application of the cleansing solution in preparation of medicines for curing women monilial vaginitis, bacterial vaginitis, trichomonas vaginitis or cervicitis, and the sterile cleansing solution for women can be used for daily hygiene care of the vagina of a woman.

An isolated microorganism that expresses enzymes of the reductive glycine pathway is disclosed. The microorganism is capable of converting formate to pyruvate or glycerate via the formation of glycine and serine. Methods of generating same are further described.

Pozzolanic cement compositions and method manufacturing the same are described. These cement compositions may include a pozzolanic material and an activator based on a salt of glycolic acid, glyceric acid, malic acid, tartaric acid, malonic acid, glutaric acid, maleic acid, formic acid, acetic acid, propionic acid, or butyric acid, a retarder based on hepto-gluconates, sulfate salts, sugars, sugar acids, lignins, and/or an accelerator based on amines. The cement compositions may have less than 10% by weight Portland cement. The pozzolanic cement compositions including these activators, accelerators, and retarders can have improved properties such as longer setting time, better slump retention, and improved strength.

The medical beautifying paste is prepared with tobacco, hickory capsule, grape vine leaf, glossy ganoderma, honeysuckle and other Chinese medicinal materials as main material; and glycerin, glyceric acid, stearic acid, beef tallow, garlic oil, vanseline and other supplementary material, and through mixing and emulsifying. It has the skin care function, obvious curative effect on acne, dermatitis, xerodermia, skin pruritus, etc. and no toxic side effect.

The invention discloses health-maintenance margarine and a preparation method thereof. The preparation method comprises the steps that an oil phase is prepared, wherein natural coconut oil, palm stearin, shea butter, aloe oil, seabuckthorn seed oil and borage oil are evenly mixed, then bisphosphoglycerate, lecithin and vitamin E are added, heating is carried out to enable oils to melt completely, and the oils are mixed evenly for use; a water phase is prepared, wherein fresh common nostoc is crushed, radiated through a microwave oven, water is then added and boiled, common nostoc water extract is obtained after filtration for use, milk powder and salt are added into deionized water and stirred sufficiently, common nostoc water extract of twice weight of the mixture is added, and even water phase is formed through stirring for use; the oil phase and the water phase are added and mixed into an emulsification tank for emulsification according to the weight ratio of 8:2, ascorbyl palmitate is added at the same time and is stirred and emulsified while being added, the emulsified lactescence is placed into a quench kneading machine to carry out tachy-coldness and kneading at the same time, cooling shaping is carried out on the kneaded emulsion matter to obtain the margarine.

The invention discloses a polyethylene and polystyrene compound radiating coating which is prepared from the following raw materials in parts by weight: 10-17 parts of brominated polystyrene, 12-15 parts of a styrene-maleic anhydride copolymer, 6-10 parts of propynol, 90-100 parts of copolymer, 4-7 parts of graphene, 16-20 parts of nano silicon dioxide, 0.2-0.3 part of a saline coupling agent KH560, 700-800 parts of dimethylformamide, 4-5 parts of sodium nitride, 0.04-0.05 part of aluminum trichloride, 1.6-2 parts of a 2-3% sodium ascorbate solution, 1.8-2 parts of a 2-3% copper sulfate solution, 120-130 parts of high density polyethylene, 1-2 parts of diacetone alcohol, 1-2 parts of glycerol triglycerate, 0.6-1 part of diacetone-acryloamide, 0.3-1 part of sp80, 2-4 parts of calcium fluoride and 1-2 parts of magnesium fluoride. The coating disclosed by the invention is blended by polyethylene and polystyrene, so that the surface strength and toughness of the coating are effectively improved and the weather resistance and the antiaging property are improved.

The invention discloses an aging-resistant PP (polypropylene) lunch box. The aging-resistant PP lunch box is prepared from the following raw materials in parts by weight: 80-90 parts of polypropylene, 20-30 parts of bisphenol A type polycarbonate, 20-30 parts of nano-calcium carbonate, 2-4 parts of stearic acid, 5-10 parts of talcum powder, 5-10 parts of carbon black, 10-15 parts of modified attapulgite, 2-3 parts of azodicarbonamide, 1-2 parts of vinyl tris(beta-methoxyethoxy) silane, 0.5-0.8 part of antioxidant CA, 0.5-0.8 part of anti-aging agent MB, 2-4 parts of propanetriol triglycerol acid ester, 1-2 parts of maleic anhydride, 0.5-1 part of zinc borate, 0.4-0.6 part of polyethylene wax and 1-2 parts of isooctyl thioglycolate dimethyl tin. The lunch box produced according to the invention has the advantages of light weight, bright and smooth surface, good chemical resistance, good dimension stability, high temperature resistance, aging resistance, high impact resistance, low breakage rate and the like.

The invention discloses a decontaminant for removing radioactive halogen. The decontaminant for removing the radioactive halogen is composed of the following components, by mass concentration: 0.5 percent to 10 percent of sodium iodide, 0.005 percent to 0.05 percent of iodophor, 0.01 percent to 0.1 percent of sodium dodecyl benzene sulfonate, 0.01 percent to 0.1 percent of glycerate, 0.01 percent to 0.05 percent of sorbitol, 5 percent to 75 percent of absolute ethyl alcohol, and the remain of distilled water. The decontaminant for removing the radioactive halogen is low in decontaminant cost and simple in preparation process, obviously removes the radioactive halogen on the surface of skin and the surface of objects, and has high clearance rate of the radioactive halogen, secondary pollution cannot be caused to environment, application range is wide, no radioactive waste water is generated, transferring of radioactive contamination cannot be caused, and secondary pollution cannot be caused. The decontaminant for removing the radioactive halogen is especially suitable for staff working on radioactive work.

The invention discloses a method for distillation synthesis of biodiesel by an acid-catalyzed reaction, and relates to a biodiesel (fatty acid methyl esters) synthesis technology and process. The method is applicable for all raw materials of oil. The method comprises the following concrete steps that: raw materials of oil, a catalyst and a small amount of methanol are mixed and pre-heated, and then enter an upper part of a catalytic distillation tower; the remaining methanol is pre-heated and enters the tower from a lower part of the tower, wherein overflow tower plates are arranged inside the tower; the rising methanol steam completely reacts with the overflowing raw materials of the oil under an effect of the acid catalyst; the methanol steam and partial water generated from the reaction are separated from the top of the tower; the product, glycerin, the acid catalyst, and the partial water settle on the bottom of the tower; a small amount of the methanol, the water and the catalyst glycerol phase are separated by a separator to obtain a semi-finished product; the semi-finished product is refined to obtain the biodiesel. According to the present invention, on the basis of the existing completely acid-catalyzed synthesis of biodiesel technology, the principle of the catalytic distillation technology is combined, the process for acid-catalyzed distillation synthesis of the biodiesel is provided, the power consumption is reduced, the reaction time is shortened, and the application scope of the raw materials is increased.

The invention provides an environment-friendly refractory material for buildings. The composite material is prepared from the following raw materials: modified phenolic resin, MgO-Al2O3-ZnO nano powder, graphene oxide modified fly ash floating beads, glass wool, expanded graphite, an excitant, a foaming agent, a foam stabilizer, a water reducing agent, perlite, ethylenediamine, adipic acid, polycaprolactone glycol, glycerol triglycerides and polyvinyl alcohol. The refractory material for buildings has the advantages of small heat conductivity coefficient, light weight, high strength, favorablethermal shock resistance, high refractoriness (higher than 1800 DEG C) and the like, thereby having wide application prospects.

The invention provides a marker for determining whether a subject has or will develop glucose impaired tolerance, or will develop type 2 diabetes. The marker includes one or more of glucose, beta-mannose monoglyceride and D-talose, and reaches diagnostic sensitivity was of 96.3%, and specificity of 0%.