29 results about "Glyceric acid" patented technology

A lipid-containing composition, by weight, includes phospholipids, and one or more of vegetable oil, medium-chain triglycerides, antioxidants, and sodium oleate. It has been verified that the various compositions provided by this invention competitively capture protein-bound toxoids in the blood, thereby achieving the purpose of clearing protein-bound toxoids from the blood, especially for patients with liver failure, and also alleviating oxidative stress in patients during dialysis treatment.

Presented herein are plants with altered photorespiratory characteristics. Disruption of transport proteins involved in shuttling glycolate and / or glycerate results in reductions in photosynthetic rates, reduced plant growth and alterations in gene expression and photosynthetic metabolite profiles. Such disruptions are also combined with introduced genes expressing components of alternate photorespiratory enzyme pathways to increase photosynthetic efficiency.

The application discloses a kind of metal ion doped dimanganese trioxide, preparation method and application thereof, manganese salt and metal nitrate are dissolved in glycerol and isopropyl alcohol, the ratio of manganese salt, metal nitrate and glycerol is (0.5-2) mmol: (0.1-0.5) mmol: (4-8) mL, to obtain mixed solution;The mixed solution is kept at 160-200 DEG C, and then the precipitate in the obtained reaction liquid is separated and then washed, dried, to obtain metal ion doped manganese glycerate;Metal ion doped manganese glycerate is calcined at 700-800 DEG C in oxygen atmosphere, to obtain metal ion doped dimanganese trioxide, by metal ion doping, adjust the electronic structure of dimanganese trioxide, improve the conductivity and optimize the ion transmission characteristics, to realize higher specific capacity, longer cycle life and better charge-discharge performance.

The application belongs to the technical field of inorganic nanometer material synthesis, and relates to a molybdenum cobalt telluride heterostructure material and a preparation method and application thereof. A divalent cobalt salt, a hexavalent molybdenum salt and glycerol are co-precipitated in isopropyl alcohol at a temperature of 160-200 DEG C to synthesize molybdenum cobalt glycerate precursor nanospheres; the molybdenum cobalt glycerate precursor nanospheres are heated to 500-600 DEG C in an air atmosphere for annealing and oxidation treatment to obtain molybdenum cobalt oxide; the molybdenum cobalt oxide and a tellurium source are heated to 550-650 DEG C in a mixed atmosphere of inert and reducing gas for annealing and tellurization treatment, and the molybdenum cobalt telluride heterostructure material is obtained. The molybdenum cobalt telluride heterostructure material provided by the application has a kind of strawberry-like structure formed by cross-linking of nanometer particles, and the molybdenum cobalt telluride heterostructure material with the structure has excellent reversibility and fast sodium storage kinetics and exhibits excellent sodium storage performance.

The invention relates to the technical field of daily chemical products and cosmetics, in particular to a scalp repair composition containing epidermis repair polysaccharide and saccharomycetes lysate. The skin repairing composition is prepared from the following raw materials in percentage by mass: 1 to 5 percent of skin repairing polysaccharide; 1%-5% of a yeast lysate; 1%-10% of PEG-5 (Polyethylene Glycol) glycerate triisostearate; and the balance of cosmetically acceptable matrix. The polysaccharide is mannan which is obtained by fermenting Paenibacillus sp.1538, and the weight-average molecular weight of the mannan is 6.15 * 10 < 6 > Da. The specific ultra-high molecular weight polysaccharide is compounded with the saccharomyces cerevisiae extract, and the low-irritation PEG-5 glycerate triisostearate is introduced, so that the compatibility problem that the high molecular weight polysaccharide is easy to flocculate is effectively solved. The composition can form a film immediately, deeply resist inflammation, relieve and repair a physical barrier of scalp, has an excellent synergistic effect, and solves the problem of scalp chemical stimulation injury caused by a traditional surfactant from the source.

The invention relates to the technical field of genetic engineering, in particular to a recombinant bacterium for high-yield serine and application of the recombinant bacterium in fermentation production of serine. The ptsI gene of escherichia coli is knocked out, a glucose PTS system is blocked, glucose transport and phosphorylation and PEP-pyruvic acid associated reaction are relieved, and pyruvic acid is synthesized by reducing serine synthesis precursor 3-phosphoglyceric acid branches. Growth adaptive evolution is further carried out on escherichia coli with the ptsI gene knocked out, an obtained mutant strain is sequenced, the mutation condition is shown in a table 2, and finally the growth rate accelerating chassis bacterium is obtained. Afterwards, by enhancing the expression serine key genes serA, serB and serC of the mutant strain and knocking out serine degradation pathway genes sdaA, sdaB and tdcG, the engineering bacterium for fermentation production of serine is constructed, and the serine yield of the engineering bacterium is remarkably improved.

Process for the preparation of menthanecarbaldehyde, comprising the following steps: - Reaction of menthone with a haloacetic acid ester of the formula XCH2COOR, with X = chlorine or bromine and R = methyl or ethyl, to form the ester of menthaneglycitic acid, - Reaction of the ester of menthaneglycitic acid thus prepared to menthanecarbaldehyde, wherein, in order to react the prepared ester of menthaneglycitic acid to menthanecarbaldehyde, the ester is reacted with a strong base such that the ester is hydrolyzed, and the hydrolysis product, as menthaneglycitic acid or as a salt of menthaneglycitic acid, is decarboxylated after intermediate isolation or without intermediate isolation.

The application discloses brake fluid for One-Box brake-by-wire system and a preparation method thereof, the brake fluid comprises triethylene glycol monomethyl ether borate, glycerol acid ester, triethylene glycol monobutyl ether, tetraethylene glycol monomethyl ether, diethylene glycol, anti-rust agent, antioxidant and pH value regulator. The brake fluid can reduce the friction coefficient to <=0.14 under the SRV test condition, the friction coefficient is reduced by 10% compared with that of traditional brake fluid, the abnormal sound and wear problem caused by poor lubrication of the brake system is effectively solved, and the reliability and safety of the brake system of the new energy vehicle are remarkably improved; in addition, the brake fluid also has low temperature kinetic viscosity (-40 DEG C) <=1000mm 2 / s, the pH value is controlled to be 7.5-8.0, and excellent corrosion prevention performance of the product is ensured.

The invention provides low-viscosity modified natural ester insulating oil and a preparation method thereof, and relates to the technical field of insulating media. Glycerate in the natural ester is converted into short-chain fatty acid ester through transesterification of the natural ester and short-chain alcohol, and then the kinematic viscosity of the product at 40 DEG C is reduced to 8 mm / s or below. According to the prepared low-viscosity modified natural ester insulating oil, the kinematic viscosity is remarkably reduced while excellent biodegradability is reserved, and the bottlenecks of low heat dissipation efficiency, high circulating energy consumption and the like caused by high viscosity of traditional natural ester are effectively overcome; meanwhile, the product also has better low-temperature fluidity and good oxidation stability.

The application discloses a preparation method of a double-shell molybdenum carbide / carbon nanosphere composite wave-absorbing material, which comprises the following steps: preparing molybdenum glycerate nanospheres, preparing polydopamine precursor nanospheres, preparing double-shell hollow structure Mo2C / C nanospheres, and detecting wave-absorbing performance, and the like. Advantages of the application are as follows: during the carbon thermal reduction process, the polydopamine is converted into a carbon skeleton while a reduction reaction occurs with the molybdenum glycerate nanospheres, a layered structure is formed while the molybdenum glycerate nanospheres are converted into molybdenum carbide and a carbon skeleton; a high carbon thermal reduction temperature improves the graphitization degree of the carbon skeleton, which is beneficial to enhancing the dielectric loss capacity of the composite material; the air stored in the double-shell hollow structure improves the inherent impedance of the material; the double-shell hollow structure forms a network structure for confining incident electromagnetic waves, enhances multiple reflection attenuation of the incident electromagnetic waves, and forms a main electromagnetic energy consumption area in the carbon shell, thereby improving electromagnetic energy loss and enhancing wave-absorbing performance.

This invention provides a multi-enzyme cascade catalytic reaction system and its application, belonging to the field of enzyme catalysis production technology. Using glycerol as a raw material, it includes a first module, a second module, and a third module. The first module involves the production of glyceric acid from glycerol under the catalysis of alditol oxidase. The second module contains glyceric acid, ATP, and NAD+. + L-glutamic acid is synthesized into phosphoserine via glycerate kinase, D-3-phosphoglycerate dehydrogenase, and phosphoserine transaminase. The third module involves phosphoserine and nucleophiles being catalyzed by phosphoserine thioylase to synthesize L-cysteine ​​or a non-natural L-α-amino acid. The multi-enzyme cascade catalytic reaction system provided by this invention can catalyze a variety of nucleophiles, yields high products, is low in cost, causes minimal environmental pollution, and is easily industrialized.

The application provides a mycoplasma hyopneumoniae culture medium capable of significantly improving the strain titer and an application thereof, and belongs to the field of veterinary biological products. The mycoplasma hyopneumoniae culture medium is obtained by adding L-asparagine, myo-inositol, arachidonic acid, urea, histamine, sodium pyruvate, valproic acid, glyceric acid, lysophosphatidic acid, L-citrulline, L-glutamine and L-leucine into a KM2 culture medium containing Bama pig serum. The culture medium can significantly improve the growth rate and viable bacterial titer of the mycoplasma hyopneumoniae under a low serum concentration, and reduces the production cost.

The present application relates to a sustained-release pharmaceutical composition of GLP-1 receptor agonist and a preparation method thereof. The composition comprises 0.05-0.5 wt% active ingredient, 45-85 wt% sustained-release agent, and 15-55 wt% viscosity reducer, or comprises 0.05-0.5 wt% active ingredient and 45-99.95 wt% thermal sensitive sustained-release agent. The active ingredient is GLP-1 receptor agonist, the sustained-release agent is polyorthoester, and the viscosity reducer is preferably glycerate compound. The present application also provides a pharmaceutical combination product comprising the sustained-release pharmaceutical composition, and application of the composition in treating metabolic related diseases. The sustained-release pharmaceutical composition has significantly improved pharmacokinetic characteristics, can realize long-acting administration, improve patient compliance, and shows excellent effects in improving blood glucose control, promoting weight loss, and improving blood lipid level.

Provided are a sustained-release pharmaceutical composition of a GLP-1 receptor agonist and a preparation method therefor. The composition contains 0.05 wt% to 0.5 wt% of an active ingredient, 45 wt% to 85 wt% of a sustained-release agent, and 15 wt% to 55 wt% of a viscosity-reducing agent, or contains 0.05 wt% to 0.5 wt% of an active ingredient, and 45 wt% to 99.95 wt% of a thermal sensitive sustained-release agent, wherein the active ingredient is a GLP-1 receptor agonist, the sustained-release agent is a polyorthoester, and the viscosity-reducing agent is preferably a glyceryl ester compound. Further provided are a drug-medical device combination product containing the sustained-release pharmaceutical composition, wherein the drug is the above-described sustained-release drug, and the medical device is a jet microneedle capable of injecting high-viscosity substances, and the use of the composition in the treatment of metabolism-related diseases. The sustained-release pharmaceutical composition has significantly improved pharmacokinetic characteristics, can realize long-acting administration, improves patient compliance, and exhibits good effects in improving blood glucose control, promoting weight loss, improving blood lipid levels, etc.

A lipid-containing composition, by weight, includes phospholipids, and one or more of vegetable oil, medium-chain triglycerides, antioxidants, and sodium oleate. It has been verified that the various compositions provided by this invention competitively capture protein-bound toxoids in the blood, thereby achieving the purpose of clearing protein-bound toxoids from the blood, especially for patients with liver failure, and also alleviating oxidative stress in patients during dialysis treatment.

Presented herein are plants with altered photorespiratory characteristics. Disruption of transport proteins involved in shuttling glycolate and / or glycerate results in reductions in photosynthetic rates, reduced plant growth and alterations in gene expression and photosynthetic metabolite profiles. Such disruptions are also combined with introduced genes expressing components of alternate photorespiratory enzyme pathways to increase photosynthetic efficiency.

This invention provides a recombinant bacterium and its applications. After specific genetic engineering modifications, this recombinant bacterium can synthesize polyhydroxybutyrate (PHB) using one-carbon compounds such as methanol or carbon dioxide as a carbon source. Specifically, the metabolic pathway of the recombinant bacterium, after optimization, enables the efficient synthesis of PHB from methanol as a raw material via metabolic intermediates such as formaldehyde, 3-phosphoglyceric acid, and acetyl-CoA. The recombinant bacterium constructed in this invention can effectively utilize low-cost carbon sources such as methanol or carbon dioxide to produce PHB, and has promising prospects for industrial application.

The application discloses a lithium manganese iron phosphate material and a preparation method thereof. A manganese iron M ternary metal-glycerate precursor is prepared by a solvent-thermal synthesis method, then is mixed with a phosphorus source and a lithium source to perform high-energy ball milling, and finally is subjected to one-time CVD sintering and two-time hot-press sintering to obtain the lithium manganese iron phosphate material. The preparation process can obtain the lithium manganese iron phosphate material with high compactness, excellent electric conductivity and cycle stability, and has high production efficiency and industrial application value.

This invention relates to the field of new materials and fine chemicals, and particularly to a novel manufacturing process technology for glycerol and pyruvate series products based on the coal chemical glycolate raw material route, including glycerol, glyceric acid, glycerate esters, pyruvate, and pyruvate esters. The process is characterized by the use of abundant coal-derived carbon monoxide (syngas), methanol, or formaldehyde, among other readily available C1 raw materials, to produce a simple and efficient series of C3-based products. This technology achieves significant cost reduction and efficiency improvement, and is conducive to the large-scale production of high-value chemicals based on my country's abundant coal resources.

This invention discloses a magnetic nanoprobe and kit for assessing postherpetic neuralgia. The magnetic nanoprobe is a complex formed by thiolized carbonized polymer dots, a chelating agent, superparamagnetic molecules, and 2-phospho-D-glyceric acid. 2-phospho-D-glyceric acid specifically reacts with NSE, dehydrating to generate phosphoenolpyruvate and releasing water molecules. The magnetic nanoprobe is specific for NSE and can be used for assessing postherpetic neuralgia. The kit includes the magnetic nanoprobe and instructions, and can determine the NSE marker content in a single sample, with a detection limit better than 1 pg / mL, thereby achieving effective assessment of postherpetic neuralgia.

The present invention relates to a room-temperature curable transparent polyurea coating composition and an exterior wall waterproofing method using the same. More specifically, the invention relates to a transparent polyurea coating composition in which a first agent and a second agent are mixed in a weight ratio of 1:0.5 to 1.5, wherein the first agent contains 100 parts by weight of a hexamethylene diisocyanate trimer (HDI Trimer) having an NCO content of 10 to 17 weight% and 1 to 20 parts by weight of a plasticizer, and the second agent comprises 100 parts by weight of an aspartic ester mixture in which a first aspartic ester having an amine equivalent of 279 and a second aspartic ester having an amine equivalent of 290 are mixed in a weight ratio of 50 to 70:30 to 50; 0.1 to 1 part by weight of a dispersant; 0.1 to 1 part by weight of an antifoaming agent; 1 to 20 parts by weight of a plasticizer; and 10 to 30 parts by weight of a solvent. The composition comprises 0.1 to 1 weight part of a UV stabilizer; and 1 to 10 weight parts of a room temperature curable additive, wherein the room temperature curable additive comprises 100 weight parts of N-phenyl-p-phenylenediamine; 10 to 30 weight parts of a gum arabic-cysteine ​​polymer; 1 to 10 weight parts of zinc glycerolate; and 1 to 10 weight parts of pyrophyllite, wherein the gum arabic-cysteine ​​polymer comprises the steps of preparing a mixture by mixing dry gum arabic and cysteine ​​in a weight ratio of 1:0.1 to 0.5 and then milling at 300 to 800 rpm for 1 to 4 hours, and washing the mixture to prepare the gum arabic-cysteine ​​polymer, thereby It offers excellent adhesion to exterior concrete surfaces, masonry walls, stone or panels, Dryvit, and exposed steel surfaces. Physical properties such as compressive strength, tensile strength, tear strength, water resistance, corrosion resistance, water resistance, chemical resistance (acid and alkali resistance), abrasion resistance, heat resistance, UV resistance, and durability can be improved. It exhibits excellent storage stability as it does not settle even during long-term storage. Furthermore, these properties are maintained even under harsh conditions (light, heat, and humidity) after application, preventing peeling, delamination, and cracking caused by physical abrasion, erosion, impact, or chemical corrosion. A perfectly transparent film layer can be formed on masonry walls with just a single application using simple manual tools such as brushes, rollers, or airless sprays. The formed transparent film layer allows for the visual identification of cracks or leaks occurring in the structure, facilitating the tracking of leaks, repair, and maintenance. Additionally, as an aliphatic polyurea, it prevents yellowing and radical The present invention relates to a room-temperature curing transparent polyurea coating composition capable of achieving a beautiful appearance without structural destruction caused by attack, and an exterior wall waterproofing method using the same.

The present application belongs to the technical field of biomass catalytic conversion and comprehensive utilization of mineral resources, and particularly relates to an oxidation catalyst and a method for preparing glyceric acid by catalytic oxidation of glycerol. The present application utilizes the components of low-grade lithium ore to prepare a catalyst, activates the synergistic catalytic action of Li, Al, Si and associated K, F and other components in the ore by a composite pretreatment process of intensified mechanical activation-high concentration acid leaching-high temperature step roasting, constructs a Li-Al-Si-K-F composite oxide heterogeneous catalyst, and realizes the efficient conversion of glycerol to glyceric acid in pure water medium with oxygen as the oxidant.

The application provides a CO2 capture method and a CO2 capture device coupled with electrochemical regeneration of hydrogen. The method comprises the following steps: absorbing CO2 in a CO2-containing gas by using an alkaline solution to form a CO2-rich solution; performing acid-base neutralization of the CO2-rich solution and an acidic solution to obtain a neutralization solution and CO2; performing electrolysis of the neutralization solution to obtain a cathode electrolysis product and an anode electrolysis product, wherein the cathode electrolysis product is H2 and the alkaline solution, and the anode electrolysis product is O2 and the acidic solution; and the acidic solution is selected from one or a combination of more than two of the following solutions: pyruvic acid solution, gluconic acid solution, malonic acid solution, tartaric acid solution, glyceric acid solution, oxalacetic acid solution, formic acid solution, isopropionic acid solution, isobutyric acid solution, fumaric acid solution, aconitic acid solution, isocitric acid solution and hexanediol diacid solution. The acidic solution generated by electrolysis can avoid corrosion of the device equipment and reduce the net energy consumption and net cost of the CO2 capture process.

The present application relates to the technical fields of epoxy resin synthesis, and particularly relates to a vegetable oil-based epoxy resin material, a preparation method and application thereof; the present application takes glycerol and fatty acid obtained by hydrolysis and separation of vegetable oil as raw materials; the fatty acid is subjected to esterification reaction with a cycloalkene alkanol compound, and the obtained product is subjected to epoxidation reaction to obtain an epoxy cycloalkyl fatty acid ester first monomer; the glycerol is subjected to esterification reaction with a cycloalkene alkanol compound, and the obtained product is subjected to epoxidation reaction to obtain a tricycloepoxy cycloalkyl glycerol ester second monomer; the first monomer and the second monomer are uniformly mixed and solidified to obtain the vegetable oil-based epoxy resin material; the material has high strength, strong weather resistance, and can be used as an adhesive, a plasticizer, a toughening agent and the like, and has wide application advantages.

The present application relates to the technical field of genetic engineering, and particularly relates to a recombinant bacteria with high yield of serine and application of the recombinant bacteria in fermentative production of serine. By knocking out ptsI gene of Escherichia coli, the present application blocks glucose PTS system, releases the association reaction between glucose transport and phosphorylation and PEP-pyruvate, and reduces the branch synthesis of pyruvate from serine synthesis precursor 3-phosphoglycerate. The present application further carries out growth adaptability evolution on the Escherichia coli with knocked out ptsI gene, and carries out sequencing on the obtained mutant strain, and the mutation is shown in Table 2. Finally, a chassis bacteria with accelerated growth rate is obtained. Then, by enhancing the expression of key serine genes serA, serB and serC of the mutant strain, and knocking out serine degradation pathway genes sdaA, sdaB and tdcG, the present application constructs an engineering bacteria for fermentative production of serine, and the serine yield of the engineering bacteria is significantly improved.

The invention belongs to the technical field of biomass catalytic conversion and comprehensive utilization of mineral resources, and particularly relates to an oxidation catalyst and a method for preparing glyceric acid by catalyzing and oxidizing glycerol through the oxidation catalyst. According to the method, the catalyst is prepared from the components of the low-grade lithium ore, the synergetic catalysis effect of Li, Al, Si, associated K, F and other components in the ore is activated through the composite pretreatment process of enhanced mechanical activation, high-concentration acid leaching and high-temperature step-by-step roasting, the Li-Al-Si-K-F composite oxide heterogeneous catalyst is constructed, oxygen is used as an oxidizing agent, and the high-quality lithium ion battery anode material is obtained. And efficient conversion from glycerol to glyceric acid is realized in a pure water medium.

This disclosure pertains to the field of battery material preparation. It provides a hollow iron phosphate, its preparation method, and its applications. The preparation method uses a specific iron source precursor, namely a spherical ferrous glycerate salt, mixed with a phosphorus source to undergo an anion exchange reaction, continuously forming hollow iron phosphate structures. This preparation method is a template-free method, requiring no additional template agent. Instead, the specific iron source precursor serves as a consumable template. The resulting hollow iron phosphate can be further used to prepare hollow lithium iron phosphate materials, which helps shorten the lithium-ion diffusion path and improve the electrochemical performance of the cathode material.

The present application relates to a kind of biological enzyme strengthening liquid and its preparation method and application, by weight parts, include the following components: crude glycerol 10-40 parts, soybean meal 3-6 parts, corn flour 3-6 parts, yeast fermentation liquor 5-40 parts, inorganic composite carrier 1-5 parts, composite biological bacteria 0.5-2 parts, composite biological enzyme 0.1-1 part and water 10-50 parts;The biological enzyme strengthening liquid of the present application is by a large number of glyceric acid small molecules homogenization carbon source and nutrient factor, and the co-metabolic degradation effect of microorganism is strengthened, with corresponding long-chain alkane degrading bacteria and extracellular enzyme, the decomposition of substrate pollutants is strengthened, trace element and electron donor activate the activity of indigenous bacteria, quickly form the symbiotic, metabolic cooperation of specific flora system, multi-collaboration, and then enhance the system resistance to impact load capacity, the COD degradation effect of oily wastewater is remarkable.

Presented herein are plants with altered photorespiratory characteristics. Disruption of transport proteins involved in shuttling glycolate and / or glycerate results in reductions in photosynthetic rates, reduced plant growth and alterations in gene expression and photosynthetic metabolite profiles. Such disruptions are also combined with introduced genes expressing components of alternate photorespiratory enzyme pathways to increase photosynthetic efficiency.