The invention relates to a method for preparing grapheme through oxidation reduction and belongs to grapheme preparation technique. The method specifically comprises the following steps: a modified Hummer method is used for preparing graphite oxide, and an oscillator is adopted for shaking and peeling off single layer graphite oxide softly. During the step of preparing grapheme through reduction, compared with kinds of conventional major reducing agents, the method has the advantages that the reduction procedures and conditions are optimized, and further the grapheme with excellent performance is obtained. In the invention, by optimizing the preparation technique and conditions, the grapheme, which is large in size, is single-layered, is excellent in electrical conductivity and has high quality is obtained, and the method has the characteristics of low cost, high product yield and easiness in industrialization.