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67 results about "PDMS stamp" patented technology

PDMS stamps are pieces of polydimethylsiloxane (PDMS), a silicone, that have been patterned usually against a master to form a relief pattern used in soft lithography. This PDMS stamp can be used in either its current form as a relief surface for techniques such as microcontact printing or can also be attached to an external source by tubing so that liquid may be passed through channels on its surface. In this second case it will often be laminated to a surface so that chemistry can be performed on that surface producing a pattern of the PDMS stamp on to the surface. Alternatively a PDMS stamp can be laminated to a second piece of PDMS to form a contained device. It is possible to pattern PDMS with nanometre resolution. PDMS stamps can be procured from some commercial sources such as Research Micro Stamps. Many techniques have been developed to modify the basic setups to perform a range of tasks such as assays on small volumes. These kinds of devices are often referred to as microfluidic devices. Because of the small dimensions of these devices flow is laminar not turbulent which can lead to many useful properties; however, this reduces the ability of fluid streams to mix.

Device for establishing single-cell level connection between neurons and growth connecting method

The invention discloses a device and a method for establishing single-cell level connection between neurons; the device comprises a basement whose upper surface is provided with protein band, and the region outside the protein band at the basement is covered by a polyether F127 layer; a PDMS stamp which is covered to the upper surface of the basement and whose lower surface is provided with a micro-groove unit; the micro-groove unit comprises: a linear type intermediate groove and at least one linear type side groove which is arranged at the left side or/and the right side of the intermediate groove, the middle section of the side groove does not intersect with the intermediate groove, and two end sections outside the middle section of the side groove incline to the direction away from the intermediate groove; the groove end is provided with a vertical hole channel; the protein band intersects with the groove without superposition; neurons are sent into the channel and only adhere to the protein band, the neurite directionally grows along the protein band without branching, thereby obtaining single-line connection of neuron single-cell level; the structure is simple, the operation is easy, and the orderly growth of the neurite can be controlled, and the electrical signal transduction between the neurocytes can be precisely studied, furthermore, the invention provides foundation support for manufacturing of bio-sensors.
Owner:THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA

PDMS elastomer micro-nano processing method based on surface oxidation control transfer printing

The invention discloses a PDMS elastomer micro-nano processing method based on surface oxidation control transfer printing. The PDMS elastomer micro-nano processing method comprises the following steps: preparing a PDMS film with an adjustable thickness to serve as a transfer printing substrate by using a pouring method or a spin coating method; preparing a PDMS film with a surface microstrucutre to serve as a transfer printing stamp by using a replica casting method; carrying out a surface oxidation treatment on the substrate or the stamp, importing a cohesive energy difference between the PDMS stamp and the planar PDMS substrate to obtain a hard / soft or soft / hard stamp-substrate combination, and simultaneously carrying out a surface activation treatment and a heating treatment on the combination to improve the contact adhesion of the two; taking off the stamp, generating cohesive energy breakage on the soft party during the separation to transfer PDMS ink to the hard party, so as to obtain a PDMS film with complex, precise and controllable concave or convex patterns on the surface. The PDMS elastomer micro-nano processing method disclosed by the method is simple and convenient to operate, low in cost, and is used for avoiding the defects of limited applicable range of other related technology and simple processing patterns.
Owner:TIANJIN UNIV

Device and method for arranging a plurality of cells at same plane and controlling cells

The invention discloses a device and a method for arranging a plurality of cells at the same plane and controlling the cells, comprising: a thin film with micro-hole arrays which is located at the upper surface of a base; a PDMS stamp whose lower surface is provided with a micro-groove unit and is coated on the thin film; the micro-groove unit comprises: an intermediate groove and a left-side groove and a right-side groove which are located at the left side and the right side of the intermediate groove; the middle sections of the left-side groove and the right-side groove are parallel to the intermediate groove; the both end sections except for the middle sections of the left-side groove and the right-side groove slant towards the direction away from the intermediate groove; the end of the groove is provided with a vertical through hole which is communicated with the corresponding groove; the holes of the thin film are all located in the micro-groove of the stamp; and a micro-pipeline is provided with different cell suspensions, the cell grows in the micro-pipeline and adheres to the micro-pipeline; the stamp is removed to realize the co-culture of a plurality of cells at the same plane; and then the thin film is removed to realize the free movement of the plurality of co-cultured cells at the same plane; the method is simple to operate, the used material is cheap, and the invention can be used for high-throughput screening of useful drugs for cells.
Owner:重庆龙翼生物科技有限公司

PDMS elastomer micro-nano processing method based on crosslinking control control transfer printing

The invention discloses a PDMS elastomer micro-nano processing method based on crosslinking control control transfer printing. The PDMS elastomer micro-nano processing method comprises the following steps: preparing a PDMS film to serve as a transfer printing substrate by using a pouring method; preparing a PDMS film with a surface microstrucutre to serve as a transfer printing stamp by using a replica casting method; importing a cohesive energy (soft / hard) difference between the PDMS stamp and the planar PDMS substrate by different crosslinking agent contents in the process of preparing the substrate and the stamp; and simultaneously carrying out an OP treatment on the prepared substrate and the stamp for 0.5 min, immediately adhering the substrate and the stamp, and carrying out a heating treatment to improve the contact adhesion of the substrate and the stamp, taking off the stamp, generating cohesive energy breakage on the soft party during the separation to transfer PDMS ink to the hard party, so as to obtain a PDMS film with concave or convex patterns on the surface. The PDMS elastomer micro-nano processing method disclosed by the method is simple and convenient to operate, low in cost, and is used for avoiding the defects of limited applicable range of other related technology and simple processing patterns.
Owner:TIANJIN UNIV

Preparation method of flexible semiconductor device

The invention belongs to the field of semiconductor manufacture, and discloses a preparation method of a flexible semiconductor device. The method includes: firstly, an inorganic semiconductor film is grown on an inorganic semiconductor substrate, then a semiconductor device based on the inorganic semiconductor film and an isolation medium layer are prepared, a groove is then etched so that the bottom of the semiconductor device maintains suspended, and finally the semiconductor device is transferred to a flexible substrate via a PDMS seal technology. The method is completely compatible with the current mainstream microelectronics technology, and the performance of the device can be effectively guaranteed via the semiconductor device prepared based on inorganic semiconductor materials; besides, the method can be widely applied to the preparation of flexible semiconductor devices of different kinds, such as light emitting diodes (LED) or field effect transistors (FET), the method can even be directly applied to the realization of flexible circuits, batch production of flexible circuit chips can be realized via the integration of the flexible packaging process, and the application values are very important.
Owner:SHANGHAI INTEGRATED CIRCUIT RES & DEV CENT +1

Preparation method and application of polyelectrolyte compound with stress response and patterned micro-nano structure

The invention relates to a preparation method and application of a polyelectrolyte compound with a stress response and a patterned micro-nano structure, in particular to a preparation method and application of the polyelectrolyte compound. The invention aims to solve the problems that an existing humidity sensor is expensive, and a compound sensor cannot realize industrial production and is not provided with relative humidity, acidity and other detection indexes. The preparation method comprises the following steps of (1) preparing a patterned PDMS stamp; (2) preparing the polyelectrolyte compound; (3) pressurizing, keeping warm and transferring to obtain the polyelectrolyte compound with the stress response and the patterned micro-nano structure. The polyelectrolyte compound with the stress response and the patterned micro-nano structure is used as an intelligent super perspective material and a stress responsive scattering medium for application, is used for detecting life food quality, and is used for a humidity sensor. According to the preparation method provided by the invention, the polyelectrolyte compound with the stress response and the patterned micro-nano structure can be obtained.
Owner:HARBIN INST OF TECH +1
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