60 results about "Tert-Butanol" patented technology

The invention relates to the technical field of organic synthesis, in particular to 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine as well as a synthesis method and application of the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodine-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and an iodine elementary substance to obtain 2-chloro-3-fluoro-4-iodine-5-methylpyridine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine, the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride, the tripotassium phosphate and the (2-formyl phenyl) boric acid, and further synthesizing the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine and the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride. And (3) synthesizing the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine by using the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine compound constructed by the invention can be used for detecting the content of pesticide residue glyphosate.

This invention discloses a catalyst for the alkylation of tert-butanol with styrene to prepare tert-butylethylbenzene and ethylbenzene, its preparation method, and its application. The catalyst consists of a support and active components loaded on the support. The active components are oxides of rare earth metals and high-valence oxides of transition metals. The support is H-β zeolite. The mass contents of the oxides of rare earth metals and high-valence oxides of transition metals on the support are 3-5% and 2-4%, respectively. This invention makes a breakthrough in the reaction mechanism by loading rare earth metals and transition metals onto a β-molecular sieve and using tert-butanol and styrene as raw materials for alkylation. This avoids the polymerization of styrene (raw material) and the dimerization of isobutylene (intermediate product), reduces the generation of by-products, and makes the catalytic process controllable.

This application relates to the field of organic synthesis technology, specifically disclosing a process for preparing tert-butyl vinyl ether. The raw materials include solid tert-butanol, acetylene, tetrahydrofuran solvent, and potassium hydroxide catalyst, supplemented with auxiliary materials such as type 3A molecular sieves and activated alumina adsorbents. The preparation method involves: after dehydration and purification of the raw materials, the materials are introduced into a reaction vessel; temperature and pressure are controlled, and the reaction endpoint is monitored using an infrared spectrometer; byproducts are quenched and acetylene is recovered; the process involves multi-stage condensation, water washing to remove impurities, distillation separation, and solvent purification and recycling, with simultaneous integration of waste heat recovery and continuous material feeding. The tert-butyl vinyl ether prepared by this process, as an important fine chemical intermediate, can be used in coatings, adhesives, and polymer material modification, possessing advantages such as high purity and good stability. The preparation method achieves efficient utilization of materials and energy through multi-stage synergistic linkage, combining the advantages of green environmental protection, continuous and stable operation, and high resource utilization.

This invention provides an intelligent control system and method for the production of tert-butane without catalytic reduction, belonging to the field of tert-butane production control. The intelligent control system includes a host computer and sensing and execution mechanisms electrically connected to the host computer. The sensing mechanisms include a TDLAS analyzer installed at the top outlet of the reactive distillation column, NIR analyzers installed at the tert-butanol inlet of the mixing preheater and the side outlet of the reactive distillation column, temperature sensors installed at the top, bottom, and side outlet of the reactive distillation column, flow meters installed at the feed inlet, top outlet, and reflux inlet of the reactive distillation column, and multiple pressure sensors spaced at equal intervals along the height of the reaction section. The execution mechanisms include electrically operated regulating valves installed at the feed inlet and reflux inlet of the reactive distillation column. The control system integrates multiple sensors and execution mechanisms, enabling closed-loop intelligent control of the entire process.

This invention relates to the technical field of imiquimod synthesis, specifically to catalysts, methods, and applications for imiquimod synthesis. The invention employs a lipase-immobilized lipase complex carrier to catalyze a transesterification reaction, using vinyl isobutyrate as the acyl donor and tert-butanol as the solvent. The hydroxyl group of 3-(4-amino-1H-imidazo[4,5-C]quinoline-1-yl)-2-methylpropane-1-ol is converted to an isobutyl side chain. Following enzymatic catalysis and pH adjustment, hydrolysis is performed to release the isobutyl group, further generating imiquimod and isobutyric acid. The lipase selectively catalyzes transesterification, avoiding side reactions, and the ester bond is rapidly hydrolyzed to the target product under acidic conditions.

The invention discloses a preparation method of 1-amino-2-cyano-1-cyclopentene, which comprises the following steps: 1, preparing a mixed solution, namely mixing a first organic solvent with super alkali in a protective gas atmosphere, heating by adopting a nano infrared energy-saving electric heating coil, stirring, uniformly mixing and dissolving to obtain the mixed solution; the super base is selected from one of potassium tert-butoxide, sodium tert-butoxide, sodium ethoxide, sodium methoxide and sodium hydroxide; 2, cyclization reaction: dropwise adding adiponitrile into the mixed solution, and continuously carrying out infrared heat preservation reaction for 3-8 hours to obtain a reaction solution of 1-amino-2-cyano-1-cyclopentene; 3, cooling crystallization and filtration: cooling the reaction liquid to-10-5 DEG C, standing for crystallization, and carrying out pressure filtration in a protective gas atmosphere to obtain an ACCP crude product and a filtrate; and 4, recrystallizing and refining to obtain a pure product. The method is mild in reaction condition, low in energy consumption, good in product yield and high in product purity, solves the problems of high solvent toxicity, low yield and high environmental protection pressure in the prior art, and is suitable for production of medicine and pesticide intermediates.

This invention relates to a method for preparing a bimetallic cyanide (DMC) catalyst, comprising a reaction of an aqueous solution of a cyanide-free metal salt, an aqueous solution of a basic metal cyanide salt, an organic complexing ligand, and optionally a component forming a complex, wherein the metal cyanide salt is one or more compounds selected from potassium hexacyanocobalt(III), potassium hexacyanoferrate(II), potassium hexacyanoferrate(III), calcium hexacyanocobalt(III), and lithium hexacyanocobalt(III), wherein the organic complexing ligand is one or more compounds selected from dimethoxyethane, tert-butanol, 2-methyl-3-buten-2-ol, 2-methyl-3-butyn-2-ol, ethylene glycol mono-tert-butyl ether, and 3-methyl-3-oxetane-methanol, and wherein the basic metal cyanide salt used has an alkalinity between 0.700 wt% and 3.000 wt% sodium hydroxide (NaOH) based on the total weight of the basic metal cyanide salt used, determined by titration as disclosed in the experimental section. Another subject of the invention includes a bimetallic cyanide catalyst (DMC) obtainable by the method according to the invention, and the use of said DMC catalyst in the preparation of polyoxyethylene polyols.

The invention relates to the technical field of tert-butyllithium preparation, in particular to a tert-butyllithium preparation method which comprises the following steps: preparing raw materials, dissolving lithium and washing oil, mixing the raw materials to start reaction, dropwise adding a modifier, carrying out heat preservation treatment, cooling, settling and taking clear liquid. According to the method, trace impurities on the surface of lithium are removed in the pretreatment link, the PVP coating can block contact of water, oxygen and lithium in a long-acting mode, lithium is prevented from going bad in the earlier stage of storage and reaction, and meanwhile the compatibility of lithium and organic solvents such as n-pentane is enhanced; the interference of impurities on the reaction can be eliminated in a high-purity state of the chlorinated tert-butane, byproducts such as lithium tert-butoxide are prevented from being generated, the moisture in the system is strictly limited by deep dehydration, a stable anhydrous environment is provided for synthesis of the tert-butyllithium, and the reaction efficiency is guaranteed; the operation of deep dehydration and impurity removal by activated aluminum oxide creates a high-cleanliness solvent system for the reaction, avoids the action of water and polar impurities with tert-butyllithium or reaction intermediates, and prevents product decomposition or impurity generation.

The invention discloses a method for recovering a tert-butyl acetate dealcoholization tower top material. Aiming at the problem that tertiary butanol and diisobutylene in a dealcoholization tower top material are unbalanced in proportion and cannot be directly recycled, the method comprises the following steps: adding a specific entrainer (such as methanol) into the material, and carrying out azeotropic distillation in a tertiary butanol recycling tower by utilizing the characteristic that the entrainer and diisobutylene form a lower-boiling-point azeotrope. An azeotrope of the entrainer and diisobutylene is extracted from the tower top, and an enriched tert-butyl alcohol material which can be directly recycled is obtained from the tower bottom. According to the method, only one rectifying tower unit is needed, the technological process is simple, the azeotrope which is difficult to treat through a traditional method is successfully separated, efficient recycling and cyclic utilization of the tert-butyl alcohol are achieved, it is not needed to purchase the tert-butyl alcohol to adjust the proportion, production raw material consumption and separation energy consumption of the tert-butyl acetate are remarkably reduced, and remarkable energy-saving and consumption-reducing benefits are achieved.

The invention relates to the technical field of organic synthesis, in particular to a synthetic method of 2, 5-dibromobenzoquinone, which takes hydroquinone as an initial raw material and comprises the following two steps: step 1, adding 0.5-2% (based on the mass of hydroquinone) of a phase transfer catalyst (such as tetrabutylammonium bromide) into a glacial acetic acid solvent, reacting with bromine at 10-15 DEG C to generate 2, 5-dibromohydroquinone, and reacting for 2-4 hours at the temperature of 10-15 DEG C to obtain 2, 5-dibromohydroquinone; after the reaction, stably storing an intermediate under the protection of inert gas; 2, oxidizing the 2, 5-dibromohydroquinone into 2, 5-dibromobenzoquinone at the temperature of 45-50 DEG C by taking acetonitrile as a solvent and adopting a tert-butyl hydroperoxide (TBHP)-sodium nitrite composite oxidant (the molar ratio is (10: 1)-(15: 1)); meanwhile, glacial acetic acid and acetonitrile mother liquor generated in the reaction process are subjected to vacuum rectification recovery (the acetonitrile recovery rate is greater than or equal to 90%, and the glacial acetic acid recovery rate is greater than or equal to 88%) for recycling. The invention solves the problems of more brominated byproducts, low oxidation efficiency, solvent waste and unstable intermediate in the prior art.

Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH4) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.

This invention discloses a beetle-based nanocellulose aerogel and its preparation method, belonging to the field of oil-water separation materials technology. The invention utilizes a hydrophilic framework formed by chemical crosslinking of lignocellulose nanofibers and polyvinyl alcohol with glutaraldehyde; oleophilic protrusions are formed by coating montmorillonite with graphene; the hydrophilic framework is immersed in a tert-butanol suspension containing the oleophilic protrusions, followed by freeze-drying to obtain the beetle-based nanocellulose aerogel. Due to the heterogeneous structure of the beetle, the hydrophilic framework enables high-speed transport of the aqueous phase, while the oleophilic protrusions efficiently capture and demulsify oil droplets. The synergistic effect of these two mechanisms achieves an ultra-high throughput greater than 10,000 L / m³. ‑2 h ‑1 With a separation efficiency of up to 95%, it effectively alleviates the trade-off between permeation flux and separation efficiency in traditional oil-water separation materials.

The invention relates to the technical field of chemical engineering, in particular to a preparation method and application of a lithium aluminum tri-tert-butoxyhydride-tetrahydrofuran solution. Industrial-grade tert-butyl alcohol is purified through molecular distillation to obtain purified tert-butyl alcohol, the purified tert-butyl alcohol and anhydrous tetrahydrofuran are mixed to prepare a tert-butyl alcohol-tetrahydrofuran solution, and then the tert-butyl alcohol-tetrahydrofuran solution is prepared into the lithium aluminum tri-tert-butoxyhydride-tetrahydrofuran solution. The method comprises the following steps: mixing a lithium aluminum hydride solid with anhydrous tetrahydrofuran, and stirring to obtain a lithium aluminum hydride-tetrahydrofuran suspension; conveying the tert-butyl alcohol-tetrahydrofuran solution and the lithium aluminum hydride-tetrahydrofuran suspension into a microchannel reactor with ultrasonic waves through a double-plunger metering pump, and reacting to obtain a product solution; and stirring the product solution, adding 2, 6-butylated hydroxytoluene, and filtering to obtain a lithium aluminum tri-tert-butoxy hydride-tetrahydrofuran solution. The continuous flow reaction is assisted by ultrasonic waves, high-efficiency and high-selectivity preparation is realized, and a stable solution product is obtained.

The invention discloses application of a boron and alkali metal salt composite synergistic system in ring-opening polymerization and copolymerization, and belongs to the field of polymer synthesis. The invention provides a dual-core or multi-core boron Lewis acid-base pair catalytic system, and particularly relates to a QC-B1 / potassium tert-butoxide / 18-C-6, CAT-B2 / potassium tert-butoxide / P5Cl and POSS-B8 / potassium tert-butoxide / P5Cl acid-base composite system, which can efficiently and controllably realize the copolymerization of epoxide and CO2 and the homopolymerization of epoxide. And carrying out copolymerization on the epoxide and CO2 to obtain the low-molecular-weight and end-functionalized polycarbonate. According to the invention, the synthesis of polycarbonate is realized by adopting a potassium alkoxide / ether or potassium alkoxide / phosphazene salt composite system and binuclear or multi-nuclear organic boron, and the problems of complex synthesis and high price of onium salt and phosphazene base halogen and phosphazene in the prior art are solved.

The invention provides a high-performance environment-friendly alcohol-based fuel. The fuel is prepared from, by weight, 80-90 parts of methanol, 2-8 parts of ethanol, 3-5 parts of tert-butanol, 0.01-0.08 part of sodium bromide, 1-2 parts of glycerin and 2-5 parts of xylene. The burning calorific value of the high-performance environment-friendly alcohol-based fuel can exceed 9000 Kcal / kg, which can meet the temperature requirement of boiler burners and large drying hearths. The fuel has a wide raw material source and a low price, and emits a small amount of harmful gas and causes little environmental pollution after burning, which achieves the purposes of energy saving and emission reduction.

The utility model discloses a continuous production device for preparing sodium tert-butoxide by using a supergravity reactor, which comprises the supergravity reactor and a liquid sodium storage tank, and a discharge port of the liquid sodium storage tank is connected with a liquid sodium feed port of the supergravity reactor through a first transfer pump; the system further comprises a tertiary butanol storage tank, a discharge port of the tertiary butanol storage tank is connected with a shell pass feed port of the heat exchanger through a second transfer pump, and a shell pass discharge port of the heat exchanger is connected with a tertiary butanol gas inlet of the supergravity reactor. And a discharge port of the supergravity reactor is connected with a feed port of the film evaporator. The high-efficiency mass transfer and mixing process of the supergravity reactor improves the reaction rate, can save a large amount of energy, and has the advantages of more uniform reactants and better reaction effect. The device adopts liquid sodium as a raw material to replace traditional solid sodium, the raw material is purer, the total alkali content of the product is higher, and the free alkali content is lower. The device adopts the film evaporator for drying, is simple in process operation, small in occupied space and high in efficiency, and can achieve continuous production of drying while reacting.

The invention discloses a method for preparing bacterial nanocellulose from animal slaughtering tail water, and relates to the technical field of biological manufacturing. The method comprises the following steps: carrying out centrifugation, alkaline proteolysis, inactivation and membrane filtration pretreatment on the animal slaughter tail water to obtain a filtrate; mixing the filtrate, a glucose solution and absolute ethyl alcohol under a sterile condition, inoculating acetobacter xylinum, and carrying out static culture to obtain a bacterial cellulose wet film; performing soda boiling purification and high-pressure microjet homogenization treatment on the wet film to obtain bacterial nano cellulose aqueous dispersion; the preparation method comprises the following steps: carrying out surface grafting on bacterial nano cellulose and nano TiO2 through a silane coupling agent to introduce double bonds, carrying out ternary free radical copolymerization with a dodecafluoroheptyl methacrylate monomer, and carrying out tertiary butanol replacement and freeze drying to prepare the bacterial nano cellulose material. According to the method, high-value utilization of slaughter tail water is achieved, and the hydrophobicity and swelling resistance of the product are effectively improved through surface chemical modification.

This invention discloses a method for synthesizing α-hydroxycarboxylic acid compounds. The method includes the following steps: adding a reaction substrate, a photosensitizer, and a base to a dry reaction tube; then adding a solvent and additives under a CO2 atmosphere; and reacting under visible light irradiation. After the reaction is complete, the reaction system is acidified and quenched, and then purified to obtain the product, the α-hydroxycarboxylic acid compound. The photosensitizer includes Ir(ppy)2(dtbbpy)PF6 and 3DPA2FBN; the base is potassium tert-butoxide, cesium carbonate, or potassium tert-valerate; the additives are N,N-diisopropylethylamine and chlorosilane; and the reaction substrate is an aldehyde or ketone compound. This invention provides a highly efficient and selective synthesis of α-hydroxycarboxylic acid compounds under visible light induction and a CO2 atmosphere. The reaction conditions of this invention are mild, the reactant range is broad, the selectivity is good, and it can be scaled up to the gram scale.

The application relates to the technical field of amide preparation, and discloses a method for preparing amide through photocatalytic oxidation and amination. The method comprises the following steps: under visible light irradiation, a nitrogen source is reacted with a hydrocarbon compound in the presence of a photocatalyst and an additive, and after post-treatment, amide is obtained; wherein the photocatalyst is a photoactive carbazole compound; the additive comprises alkaline substances and acidic substances; and the hydrocarbon compound is selected from one or more of C3-C11 chain alkanes, C3-C11 cycloalkanes and C3-C11 alkyl-substituted aromatic hydrocarbons. According to the method, a C-C bond in a low or medium hydrocarbon compound is directly oxidized and aminated to break and synthesize chain amide or lactam through photocatalysis. The method has mild reaction conditions, avoids the use of a high-pressure mercury lamp or other ultraviolet lamps, avoids the generation of tar and coke under ultraviolet conditions, and avoids the use of a large amount of alcohol additives such as t-butyl alcohol.

The invention belongs to the technical field of fine chemical engineering, and particularly relates to a synthesis method of (E, Z)-2, 6-nonadien-1-ol and (E, Z)-2, 6-nonadienal. The method comprises the following steps of: reacting cis-leaf alcohol serving as a starting material with phosphorus oxybromide to generate cis-1-bromo-3-hexene, reacting the cis-1-bromo-3-hexene with magnesium metal to obtain cis-3-hexenyl Grignard magnesium bromide, reacting the cis-3-hexenyl Grignard magnesium bromide with formaldehyde to generate cis-4-heptene-1-alcohol, oxidizing the cis-4-heptene-1-alcohol with sodium hypochlorite under the catalysis of a catalyst 2, 2, 6, 6-tetramethylpiperidine oxide to obtain cis-4-heptene-1-aldehyde, and separating the cis-4-heptene-1-aldehyde from the cis-4-heptene-1-aldehyde. The preparation method comprises the following steps: reacting (E, Z)-2, 6-nonadienoic acid methyl ester with methoxyl formyl methylene triphenyl halophosphine in the presence of potassium tert-butoxide to obtain (E, Z)-2, 6-nonadienoic acid methyl ester, reducing the (E, Z)-2, 6-nonadienoic acid methyl ester with NaBH4 to obtain (E, Z)-2, 6-nonadien-1-ol, and finally oxidizing the (E, Z)-2, 6-nonadienal with sodium hypochlorite under the catalysis of a catalyst 2, 2, 6, 6-tetramethylpiperidine oxide to obtain (E, Z)-2, 6-nonadienal. The method is environment-friendly, low in cost and suitable for industrial production.

This invention relates to the field of pharmaceutical preparations, specifically to a method for preparing a lyophilized bortezomib for injection. The method for preparing a lyophilized bortezomib for injection provided by this invention includes preparing bortezomib mannitol ester and preparing a lyophilized bortezomib for injection. The preparation of bortezomib mannitol ester includes the following steps: adding mannitol to purified water and stirring to dissolve it to form a mannitol solution; adding tert-butanol to the mannitol solution and stirring until homogeneous to form a mixture; adding bortezomib to the resulting mixture and stirring until completely dissolved to form a bortezomib mannitol ester solution; filtering the resulting bortezomib mannitol ester solution, dispensing the filtrate into stainless steel trays, and placing them in a lyophilization chamber; lyophilizing, collecting the lyophilized powder, and obtaining bortezomib mannitol ester. This invention effectively overcomes the problems of foreign matter in lyophilized bortezomib preparations and poor clarity after reconstitution.

This invention discloses a method for preparing organothioether compounds, using thiophenol compounds and olefins as raw materials, and reacting them with an alkalizing agent and a catalyst in a solvent under blue light irradiation at room temperature. The method involves using a tert-butanol salt to abstract a hydrogen atom at the S-position of R-thiophenol, generating an R-thiophenol anion. Under light irradiation, the R-thiophenol anion loses electrons to generate an R-thiophenol free radical. The R-thiophenol free radical then passes through Fe... 3+ The method involves catalytic reaction with olefins to yield organosulfur ethers. This well-designed method does not rely on halogens, is relatively reactor- and environmentally friendly, achieves a yield of up to 65%, and is cost-effective. It provides a novel approach for the synthesis of organosulfur ethers and shows promise for industrial applications.

The present application relates to the technical field of organic synthesis, and particularly relates to 4-chloro-1-methyl-6H-isochromeno[3,4-c]pyridine and a synthesis method and application thereof. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodo-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and iodine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridin-4-yl)benzaldehyde from 2-chloro-3-fluoro-4-iodo-5-methylpyridine, 1,1-bis(diphenylphosphino)ferrocene palladium dichloride, potassium phosphate and (2-formylphenyl)boronic acid; and (3) synthesizing 4-chloro-1-methyl-6H-isochromeno[3,4-c]pyridine from 2-(2-chloro-3-fluoro-5-methylpyridin-4-yl)benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-isochromeno[3,4-c]pyridine compound constructed by the present application can be used for detecting the content of the pesticide glyphosate.

This invention relates to the deposition of an alumina etch stop layer. It is characterized by a dielectric constant (k) less than about 7 (e.g., between about 4 and 6) and a density of at least about 2.5 g / cm³. 3 (For example, between approximately 3.0 and 3.2 g / cm³) 3 An alumina film (between metal and dielectric layers) is deposited on partially fabricated semiconductor devices as an etch stop layer. A deposition method that does not cause oxidative damage to the metal is used to deposit the film. Deposition involves reacting an aluminum-containing precursor (e.g., trialkylaluminum) with an alcohol and / or alkoxyaluminum. In one implementation, the method involves flowing trimethylaluminum into a processing chamber housing a substrate with exposed metal and dielectric layers; cleaning and / or evacuating the processing chamber; flowing tert-butanol into the processing chamber and reacting it with trimethylaluminum to form an alumina film; and repeating these process steps until a film of the desired thickness is formed.

The invention provides a molecular sieve membrane based on a nutrient-rich solution as well as a preparation method and application of the molecular sieve membrane, and belongs to the technical field of inorganic molecular sieve membrane materials and membrane separation. According to the method, a high-nutrition reaction system is constructed, the composition of a silicon source and an alkali source is accurately regulated and controlled, rapid nucleation and efficient growth of molecular sieve crystals are realized in a relatively short time, and the high-crystallinity molecular sieve seed crystal is prepared; then uniformly loading the seed crystal on the surface of the porous support body to form a continuous and compact seed crystal layer; and then carrying out short-time hydrothermal growth by utilizing the eutrophic reaction liquid, and rapidly constructing the molecular sieve membrane with a complete structure and controllable thickness. The preparation method disclosed by the invention is simple and efficient, the preparation period of the molecular sieve membrane is effectively shortened, alternation and dense accumulation among crystals are promoted, and the generation of membrane defects is remarkably reduced. The prepared molecular sieve membrane shows excellent separation performance in pervaporation separation application of water and low-molecular-weight and low-polarity organic solvents (such as acetonitrile, ethanol, acetone, isopropanol, tetrahydrofuran, n-butyl alcohol, tert-butyl alcohol and dimethyl carbonate), and has a good industrial application prospect.

The invention discloses a recovery method of ester peroxide waste, and belongs to the technical field of organic peroxide recovery. The method comprises the following steps: firstly, carrying out low-temperature freezing-inert gas protection treatment, adding a stabilizer to obtain a pretreated waste material, effectively inhibiting decomposition from three dimensions of reducing reaction activity, isolating decomposition-assisting substances and chemically capturing free radicals, and providing a preliminary stable environment for unstable ester peroxide waste materials; the method comprises the following steps: accurately removing acid by using a saturated sodium bicarbonate solution, removing water by using anhydrous magnesium sulfate, filtering and washing, removing tertiary butanol, ketones, alkanes and other small molecular impurities by using a membrane technology, finally obtaining a purified ester peroxide product through reduced pressure rectification, and adding a stabilizer into the product for protection. The recovery method provided by the invention adapts to the characteristics of high sensitivity and impurity complexity of the tert-butyl peroxide ester waste, and simultaneously solves the three core problems of safety, recovery efficiency and product purity in the recovery process.

The application discloses a low interfacial tension high-stable foam system for controlling the mobility of CO2 flooding of thick oil, which comprises 0.05-0.5% of a foaming agent, 0.01-1% of a thick oil active inducer and the rest of water in percentage by mass; the foaming agent is compounded by a non-ionic surfactant and an ionic surfactant at a mass ratio of 5:1-1:5; and the thick oil active inducer is one or more of sodium carbonate, ammonium carbonate, potassium carbonate, sodium hydroxide, sodium tert-butoxide, sodium tetraborate, sodium ethoxide, ethylenediamine, diisopropyl alcohol amine and triethylamine. The application can form high-stable foam in the CO2 channeling channel of the thick oil reservoir containing residual oil, effectively inhibit CO2 channeling and expand the CO2 sweeping efficiency; the application can reduce the interfacial tension between the foam system and the thick oil, and further improve the oil washing efficiency of the thick oil reservoir; and the application can use the thick oil active inducer to enhance the foam system to improve the recovery efficiency and reduce the system cost.

This invention belongs to the field of nanomaterials, specifically relating to a method for exfoliating two-dimensional layered nanomaterials. The method involves ultrasonically dispersing layered nanomaterial powder in a precursor solution, controlling the solution pH, allowing it to stand, filtering, and collecting the filtrate. The precursor-two-dimensional layered nanomaterial mixture is then heated in a water bath, the solution pH is adjusted, stirred, centrifuged at high speed, and the filtrate is discarded. Following vacuum distillation, washing, and drying, the two-dimensional layered nanomaterials are obtained. The layered nanomaterials refer to graphitic carbon nitride nanosheets. The precursor is prepared by the following steps: a 1 mol / L solution of tert-butanol and tert-butylamine is prepared as a carrier; N,N-dimethylformamide and dimethyl sulfoxide are mixed uniformly; benzoyl peroxide is added slowly while stirring to the carrier prepared in step A1 to obtain the precursor. The two-dimensional graphitic carbon nitride nanosheets obtained by this invention have the characteristics of high yield and large specific surface area.

The invention belongs to the technical field of chemical synthesis, and discloses a preparation method of a medical intermediate, and the name of the specific compound is 3, 3-difluoro-4-oxopiperidine-1-carboxylic acid tert-butyl ester monohydrate. A brand new synthesis route is provided, and the six-step synthesis method comprises the following steps: taking 2, 4-dimethoxybenzylamine as an initial raw material, dropwise adding ethyl acrylate at the temperature of 30-40 DEG C, and stirring for reaction to obtain an intermediate 1; continuously adding benzotriazole, dropwise adding a 37% formaldehyde aqueous solution, and obtaining an intermediate 2 under the condition of room temperature; continuously adding zinc powder, controlling the temperature of the room, dropwise adding trimethylchlorosilane and ethyl bromodifluoroacetate, and stirring and reacting at room temperature to obtain an intermediate 3; continuously adding one of sodium methoxide, sodium ethoxide or potassium tert-butoxide, and stirring at room temperature to completely react to obtain an intermediate 4; adding a 16% sodium hydroxide solution while stirring, heating to 95-100 DEG C, and stirring for reaction to obtain an intermediate 5; controlling the temperature to be 10-20 DEG C, dropwise adding trifluoroacetic acid, and stirring at room temperature to react completely; and performing post-treatment on the reaction liquid to obtain a product. And a green, safe and high-yield kilogram-level process easy for industrial production is established. A stable and cheap intermediate source is provided for innovative drugs, the yield is increased, and the competitiveness of the innovative drugs is improved.

This application discloses a multi-electron transfer polynuclear quinoxaline derivative and its synthesis method and application, relating to the field of electrochemical energy storage. The method involves dissolving cyclohexanehexaone octahydrate and 4,5-dichloro-1,2-phenylenediamine or 4-chloro-1,2-phenylenediamine in a mixed solution of glacial acetic acid and anhydrous ethanol. The solution is refluxed and stirred at high temperature under N2 protection for 24 hours. The product is then refluxed and stirred at high temperature in dilute nitric acid for 3 hours to obtain intermediate products HATN-HC or HATN-TC. HATN-HC or HATN-TC, potassium tert-butoxide, mercaptopropionic acid, manganese dioxide, and 15-crown ether-5 are added to anhydrous ethanol. The mixture is stirred and reacted at 70°C under N2 protection for 24 hours. The product is filtered, washed, and acidified, then dried at 60°C in a vacuum oven to obtain HATN-HSPA or HATN-TSPA. The application of the multi-electron transfer polynuclear quinoxaline derivative in alkaline aqueous organic flow batteries is also discussed.