100 results about "Tert-Butanol" patented technology

The invention discloses a preparation method of linolenic acid structural ester with synergistic biological activity, and relates to the technical field of linolenic acid structural ester preparation.The preparation method comprises the steps that specific lipase is prepared through rhizopus wei, and after an SBA-15 molecular sieve is treated, the lipase is fixed to prepare a composite catalyst; the preparation method comprises the following steps: after hydroxyl protection of quercetin, esterifying quercetin with EPA to obtain quercetin-EPA ester; esterifying glycerol and linolenic acid in the presence of a composite catalyst and microwaves, and purifying to obtain an intermediate product; carrying out microwave catalytic ester exchange on the intermediate product and quercetin-EPA ester in tert-butyl alcohol through a composite catalyst to obtain a crude product; and removing impurities from the crude product by a urea adduction method, and carrying out molecular distillation graded purification, column chromatography, deodorization and filtration to obtain a final product. According to the invention, linolenic acid, quercetin and EPA are combined through molecular design to form a compound structure ester with a multi-target effect, and the linolenic acid, quercetin and EPA achieve functional complementation through a synergistic effect, so that the biological activity of the compound structure ester is enhanced.

The invention relates to the technical field of organic synthesis, in particular to 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine as well as a synthesis method and application of the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine. The synthesis method comprises the following steps: (1) synthesizing 2-chloro-3-fluoro-4-iodine-5-methylpyridine from 2-chloro-3-fluoro-5-methylpyridine and an iodine elementary substance to obtain 2-chloro-3-fluoro-4-iodine-5-methylpyridine; (2) synthesizing 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine, the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride, the tripotassium phosphate and the (2-formyl phenyl) boric acid, and further synthesizing the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde from the 2-chloro-3-fluoro-4-iodo-5-methylpyridine and the 1, 1-bis (diphenylphosphine) ferrocene palladium dichloride. And (3) synthesizing the 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine by using the 2-(2-chloro-3-fluoro-5-methylpyridine-4-yl) benzaldehyde and sodium tert-butoxide. The 4-chloro-1-methyl-6H-heterochromene [3, 4-c] pyridine compound constructed by the invention can be used for detecting the content of pesticide residue glyphosate.

This invention discloses a catalyst for the alkylation of tert-butanol with styrene to prepare tert-butylethylbenzene and ethylbenzene, its preparation method, and its application. The catalyst consists of a support and active components loaded on the support. The active components are oxides of rare earth metals and high-valence oxides of transition metals. The support is H-β zeolite. The mass contents of the oxides of rare earth metals and high-valence oxides of transition metals on the support are 3-5% and 2-4%, respectively. This invention makes a breakthrough in the reaction mechanism by loading rare earth metals and transition metals onto a β-molecular sieve and using tert-butanol and styrene as raw materials for alkylation. This avoids the polymerization of styrene (raw material) and the dimerization of isobutylene (intermediate product), reduces the generation of by-products, and makes the catalytic process controllable.

The invention discloses a ruthenium metal complex and a preparation method and application thereof, and belongs to the technical field of organic metal synthesis. The preparation method of the ruthenium metal complex specifically comprises the following steps: (1) under anhydrous and anaerobic conditions, adding ethylene glycol monoethyl ether and RuCl3.H2O into a reaction flask, introducing CO, heating, and reacting; (2) continuously heating, reacting and cooling; and (3) adding 3-chloro-2-methylpropan-1-ene, uniformly mixing, heating, stirring, cooling, adding a potassium tert-butoxide tetrahydrofuran solution, heating until boiling, stirring again, stopping heating, reacting, filtering, cleaning a filter cake with tetrahydrofuran, removing the solvent from the filtrate to obtain a reddish brown oily liquid, and condensing to obtain a Ru (tmm) (CO) 3 product, namely the ruthenium metal complex. The ruthenium metal complex prepared by the method has the advantages of high yield (62.8%), high purity (99.6%), low synthesis cost and simple synthesis steps.

This application relates to the field of organic synthesis technology, specifically disclosing a process for preparing tert-butyl vinyl ether. The raw materials include solid tert-butanol, acetylene, tetrahydrofuran solvent, and potassium hydroxide catalyst, supplemented with auxiliary materials such as type 3A molecular sieves and activated alumina adsorbents. The preparation method involves: after dehydration and purification of the raw materials, the materials are introduced into a reaction vessel; temperature and pressure are controlled, and the reaction endpoint is monitored using an infrared spectrometer; byproducts are quenched and acetylene is recovered; the process involves multi-stage condensation, water washing to remove impurities, distillation separation, and solvent purification and recycling, with simultaneous integration of waste heat recovery and continuous material feeding. The tert-butyl vinyl ether prepared by this process, as an important fine chemical intermediate, can be used in coatings, adhesives, and polymer material modification, possessing advantages such as high purity and good stability. The preparation method achieves efficient utilization of materials and energy through multi-stage synergistic linkage, combining the advantages of green environmental protection, continuous and stable operation, and high resource utilization.

The invention relates to the technical field of synthesis of carbon nitride flame-retardant materials, and particularly discloses a synthesis method of melam, which comprises the following steps: by taking cyanuric chloride as a raw material, carrying out ammoniation and coupling to obtain a bis-triazine intermediate, and carrying out sealed ammoniation on the bis-triazine intermediate by using ammonia water to obtain melam; the optimal potassium tert-butoxide enables the BDCAT to be obtained at the yield of more than 60% in the second-step reaction, the ammonia water ammoniation process used in the third-step reaction is relatively safe, the synthesis method is simple and efficient, and the harsh requirement of a high-temperature and high-pressure method on equipment is avoided.

This invention discloses a bicyclic [2.1.1]hexene compound and its preparation and application. The invention uses bicyclic [1.1.0]butanone and phosphate ester as starting materials, and potassium tert-butoxide tetrahydrofuran solution as base. The reaction is carried out under reflux at 80°C to obtain the bicyclic [2.1.1]hexene compound. The prepared compound has certain transpeptidase inhibitory activity and can effectively inhibit the infection and spread of Staphylococcus aureus.

This invention provides an intelligent control system and method for the production of tert-butane without catalytic reduction, belonging to the field of tert-butane production control. The intelligent control system includes a host computer and sensing and execution mechanisms electrically connected to the host computer. The sensing mechanisms include a TDLAS analyzer installed at the top outlet of the reactive distillation column, NIR analyzers installed at the tert-butanol inlet of the mixing preheater and the side outlet of the reactive distillation column, temperature sensors installed at the top, bottom, and side outlet of the reactive distillation column, flow meters installed at the feed inlet, top outlet, and reflux inlet of the reactive distillation column, and multiple pressure sensors spaced at equal intervals along the height of the reaction section. The execution mechanisms include electrically operated regulating valves installed at the feed inlet and reflux inlet of the reactive distillation column. The control system integrates multiple sensors and execution mechanisms, enabling closed-loop intelligent control of the entire process.

This invention relates to the technical field of imiquimod synthesis, specifically to catalysts, methods, and applications for imiquimod synthesis. The invention employs a lipase-immobilized lipase complex carrier to catalyze a transesterification reaction, using vinyl isobutyrate as the acyl donor and tert-butanol as the solvent. The hydroxyl group of 3-(4-amino-1H-imidazo[4,5-C]quinoline-1-yl)-2-methylpropane-1-ol is converted to an isobutyl side chain. Following enzymatic catalysis and pH adjustment, hydrolysis is performed to release the isobutyl group, further generating imiquimod and isobutyric acid. The lipase selectively catalyzes transesterification, avoiding side reactions, and the ester bond is rapidly hydrolyzed to the target product under acidic conditions.

The invention discloses a preparation method of 1-amino-2-cyano-1-cyclopentene, which comprises the following steps: 1, preparing a mixed solution, namely mixing a first organic solvent with super alkali in a protective gas atmosphere, heating by adopting a nano infrared energy-saving electric heating coil, stirring, uniformly mixing and dissolving to obtain the mixed solution; the super base is selected from one of potassium tert-butoxide, sodium tert-butoxide, sodium ethoxide, sodium methoxide and sodium hydroxide; 2, cyclization reaction: dropwise adding adiponitrile into the mixed solution, and continuously carrying out infrared heat preservation reaction for 3-8 hours to obtain a reaction solution of 1-amino-2-cyano-1-cyclopentene; 3, cooling crystallization and filtration: cooling the reaction liquid to-10-5 DEG C, standing for crystallization, and carrying out pressure filtration in a protective gas atmosphere to obtain an ACCP crude product and a filtrate; and 4, recrystallizing and refining to obtain a pure product. The method is mild in reaction condition, low in energy consumption, good in product yield and high in product purity, solves the problems of high solvent toxicity, low yield and high environmental protection pressure in the prior art, and is suitable for production of medicine and pesticide intermediates.

This invention relates to a method for preparing a bimetallic cyanide (DMC) catalyst, comprising a reaction of an aqueous solution of a cyanide-free metal salt, an aqueous solution of a basic metal cyanide salt, an organic complexing ligand, and optionally a component forming a complex, wherein the metal cyanide salt is one or more compounds selected from potassium hexacyanocobalt(III), potassium hexacyanoferrate(II), potassium hexacyanoferrate(III), calcium hexacyanocobalt(III), and lithium hexacyanocobalt(III), wherein the organic complexing ligand is one or more compounds selected from dimethoxyethane, tert-butanol, 2-methyl-3-buten-2-ol, 2-methyl-3-butyn-2-ol, ethylene glycol mono-tert-butyl ether, and 3-methyl-3-oxetane-methanol, and wherein the basic metal cyanide salt used has an alkalinity between 0.700 wt% and 3.000 wt% sodium hydroxide (NaOH) based on the total weight of the basic metal cyanide salt used, determined by titration as disclosed in the experimental section. Another subject of the invention includes a bimetallic cyanide catalyst (DMC) obtainable by the method according to the invention, and the use of said DMC catalyst in the preparation of polyoxyethylene polyols.

The invention relates to the technical field of tert-butyllithium preparation, in particular to a tert-butyllithium preparation method which comprises the following steps: preparing raw materials, dissolving lithium and washing oil, mixing the raw materials to start reaction, dropwise adding a modifier, carrying out heat preservation treatment, cooling, settling and taking clear liquid. According to the method, trace impurities on the surface of lithium are removed in the pretreatment link, the PVP coating can block contact of water, oxygen and lithium in a long-acting mode, lithium is prevented from going bad in the earlier stage of storage and reaction, and meanwhile the compatibility of lithium and organic solvents such as n-pentane is enhanced; the interference of impurities on the reaction can be eliminated in a high-purity state of the chlorinated tert-butane, byproducts such as lithium tert-butoxide are prevented from being generated, the moisture in the system is strictly limited by deep dehydration, a stable anhydrous environment is provided for synthesis of the tert-butyllithium, and the reaction efficiency is guaranteed; the operation of deep dehydration and impurity removal by activated aluminum oxide creates a high-cleanliness solvent system for the reaction, avoids the action of water and polar impurities with tert-butyllithium or reaction intermediates, and prevents product decomposition or impurity generation.

The invention discloses a method for recovering a tert-butyl acetate dealcoholization tower top material. Aiming at the problem that tertiary butanol and diisobutylene in a dealcoholization tower top material are unbalanced in proportion and cannot be directly recycled, the method comprises the following steps: adding a specific entrainer (such as methanol) into the material, and carrying out azeotropic distillation in a tertiary butanol recycling tower by utilizing the characteristic that the entrainer and diisobutylene form a lower-boiling-point azeotrope. An azeotrope of the entrainer and diisobutylene is extracted from the tower top, and an enriched tert-butyl alcohol material which can be directly recycled is obtained from the tower bottom. According to the method, only one rectifying tower unit is needed, the technological process is simple, the azeotrope which is difficult to treat through a traditional method is successfully separated, efficient recycling and cyclic utilization of the tert-butyl alcohol are achieved, it is not needed to purchase the tert-butyl alcohol to adjust the proportion, production raw material consumption and separation energy consumption of the tert-butyl acetate are remarkably reduced, and remarkable energy-saving and consumption-reducing benefits are achieved.

The invention relates to the technical field of organic synthesis, in particular to a synthetic method of 2, 5-dibromobenzoquinone, which takes hydroquinone as an initial raw material and comprises the following two steps: step 1, adding 0.5-2% (based on the mass of hydroquinone) of a phase transfer catalyst (such as tetrabutylammonium bromide) into a glacial acetic acid solvent, reacting with bromine at 10-15 DEG C to generate 2, 5-dibromohydroquinone, and reacting for 2-4 hours at the temperature of 10-15 DEG C to obtain 2, 5-dibromohydroquinone; after the reaction, stably storing an intermediate under the protection of inert gas; 2, oxidizing the 2, 5-dibromohydroquinone into 2, 5-dibromobenzoquinone at the temperature of 45-50 DEG C by taking acetonitrile as a solvent and adopting a tert-butyl hydroperoxide (TBHP)-sodium nitrite composite oxidant (the molar ratio is (10: 1)-(15: 1)); meanwhile, glacial acetic acid and acetonitrile mother liquor generated in the reaction process are subjected to vacuum rectification recovery (the acetonitrile recovery rate is greater than or equal to 90%, and the glacial acetic acid recovery rate is greater than or equal to 88%) for recycling. The invention solves the problems of more brominated byproducts, low oxidation efficiency, solvent waste and unstable intermediate in the prior art.

Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH4) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.

This invention discloses a beetle-based nanocellulose aerogel and its preparation method, belonging to the field of oil-water separation materials technology. The invention utilizes a hydrophilic framework formed by chemical crosslinking of lignocellulose nanofibers and polyvinyl alcohol with glutaraldehyde; oleophilic protrusions are formed by coating montmorillonite with graphene; the hydrophilic framework is immersed in a tert-butanol suspension containing the oleophilic protrusions, followed by freeze-drying to obtain the beetle-based nanocellulose aerogel. Due to the heterogeneous structure of the beetle, the hydrophilic framework enables high-speed transport of the aqueous phase, while the oleophilic protrusions efficiently capture and demulsify oil droplets. The synergistic effect of these two mechanisms achieves an ultra-high throughput greater than 10,000 L / m³. ‑2 h ‑1 With a separation efficiency of up to 95%, it effectively alleviates the trade-off between permeation flux and separation efficiency in traditional oil-water separation materials.

The invention relates to the technical field of chemical engineering, in particular to a preparation method and application of a lithium aluminum tri-tert-butoxyhydride-tetrahydrofuran solution. Industrial-grade tert-butyl alcohol is purified through molecular distillation to obtain purified tert-butyl alcohol, the purified tert-butyl alcohol and anhydrous tetrahydrofuran are mixed to prepare a tert-butyl alcohol-tetrahydrofuran solution, and then the tert-butyl alcohol-tetrahydrofuran solution is prepared into the lithium aluminum tri-tert-butoxyhydride-tetrahydrofuran solution. The method comprises the following steps: mixing a lithium aluminum hydride solid with anhydrous tetrahydrofuran, and stirring to obtain a lithium aluminum hydride-tetrahydrofuran suspension; conveying the tert-butyl alcohol-tetrahydrofuran solution and the lithium aluminum hydride-tetrahydrofuran suspension into a microchannel reactor with ultrasonic waves through a double-plunger metering pump, and reacting to obtain a product solution; and stirring the product solution, adding 2, 6-butylated hydroxytoluene, and filtering to obtain a lithium aluminum tri-tert-butoxy hydride-tetrahydrofuran solution. The continuous flow reaction is assisted by ultrasonic waves, high-efficiency and high-selectivity preparation is realized, and a stable solution product is obtained.

The invention belongs to the field of small molecule synthesis, and particularly relates to a synthesis method of 4-methyl-4, 7-diazaspiro [2.5] octane hydrochloric acid. According to the synthetic route provided by the invention, the target product can be synthesized by only three steps, and the reaction safety and the yield are remarkably improved by optimizing the preparation process of the key intermediate compound 2 and the compound 3 and adopting potassium tert-butoxide and tetraisopropyl titanate to respectively replace dangerous reagents as catalysts. The method is easy and convenient to operate and suitable for industrial production, and an efficient way is provided for synthesis of medical intermediates.

The invention discloses bionic Al2O3 porous ceramic with a bidirectional gradient structure and a preparation method of the bionic Al2O3 porous ceramic, and belongs to the field of ceramic material preparation. Aiming at the problem that a multi-directional gradient structure is difficult to construct by a traditional freezing casting technology, bidirectional gradient regulation and control of a pore structure and components along a freezing direction and a magnetic field direction are realized through a synergistic effect of magnetic field assisted freezing casting and a non-aqueous solvent system. The porous ceramic takes Al2O3 as a matrix, is doped with 3wt.%-9wt.% of Ni powder as a magnetic additive, and takes tert-butyl alcohol (TBA) as a solvent to form bidirectional gradient distribution: the pore diameter and the wall thickness in the freezing direction change in a gradient manner; gradient distribution of a Ni enrichment area (pore orientation parallel magnetic field) and a Ni depletion area (pore orientation parallel freezing direction) is formed in the magnetic field direction. The preparation method comprises the steps of slurry preparation, magnetic field-assisted directional solidification, freeze drying and high-temperature sintering. The method is simple and controllable in process, and is suitable for the fields of biomedical bone repair, environmental filtration, battery energy and the like.

Provided is a 3, 5, 5-trimethylhexanoic acid composition which contains 3, 5, 5-trimethylhexanoic acid and tertiary butanol, and which has a deuterated toluene-converted concentration of more than 0 to 400 volume ppb (inclusive) as measured by smelling gas chromatography / mass spectrometry after heating in an air atmosphere at 80 DEG C for 4 weeks. The composition has low reproductive toxicity even if stored for a long period of time. (Measurement Condition). The 3, 5, 5-trimethylhexanoic acid composition is concentrated. And measuring the concentrated sample by smelling gas chromatography using a column in which the stationary phase is dimethyl polysiloxane, and analyzing the structure of the measured components by a mass spectrometry detector.

The invention relates to a preparation method of a kaolinite-Zr-MOF material, in particular to a preparation method of a kaolinite-Zr-MOF material for removing phosphate radicals and tetracycline in a water body, and the preparation method comprises the following steps: S1, preparing silanized kaolinite; s2, preparing an MOF composite material, then adding a FeCl solution, raising the temperature to 120 DEG C, and maintaining the temperature for 30-40 minutes to obtain a product 5; and S4, cooling the product 5 to room temperature, centrifuging, taking supernate, retaining a fixed product, washing the fixed product with tert-butyl alcohol / water, and freeze-drying to obtain the kaolinite-Zr-MOF material. In the scheme, toxic solvents such as DMF are not adopted in the whole process, only solvents such as terephthalic acid, acetic acid and tert-butyl alcohol are adopted, and compared with the prior art, the method is more environmentally friendly. The method has a good removal effect on phosphate radicals and tetracycline.

The invention discloses application of a boron and alkali metal salt composite synergistic system in ring-opening polymerization and copolymerization, and belongs to the field of polymer synthesis. The invention provides a dual-core or multi-core boron Lewis acid-base pair catalytic system, and particularly relates to a QC-B1 / potassium tert-butoxide / 18-C-6, CAT-B2 / potassium tert-butoxide / P5Cl and POSS-B8 / potassium tert-butoxide / P5Cl acid-base composite system, which can efficiently and controllably realize the copolymerization of epoxide and CO2 and the homopolymerization of epoxide. And carrying out copolymerization on the epoxide and CO2 to obtain the low-molecular-weight and end-functionalized polycarbonate. According to the invention, the synthesis of polycarbonate is realized by adopting a potassium alkoxide / ether or potassium alkoxide / phosphazene salt composite system and binuclear or multi-nuclear organic boron, and the problems of complex synthesis and high price of onium salt and phosphazene base halogen and phosphazene in the prior art are solved.

The invention provides a high-performance environment-friendly alcohol-based fuel. The fuel is prepared from, by weight, 80-90 parts of methanol, 2-8 parts of ethanol, 3-5 parts of tert-butanol, 0.01-0.08 part of sodium bromide, 1-2 parts of glycerin and 2-5 parts of xylene. The burning calorific value of the high-performance environment-friendly alcohol-based fuel can exceed 9000 Kcal / kg, which can meet the temperature requirement of boiler burners and large drying hearths. The fuel has a wide raw material source and a low price, and emits a small amount of harmful gas and causes little environmental pollution after burning, which achieves the purposes of energy saving and emission reduction.

The utility model discloses a continuous production device for preparing sodium tert-butoxide by using a supergravity reactor, which comprises the supergravity reactor and a liquid sodium storage tank, and a discharge port of the liquid sodium storage tank is connected with a liquid sodium feed port of the supergravity reactor through a first transfer pump; the system further comprises a tertiary butanol storage tank, a discharge port of the tertiary butanol storage tank is connected with a shell pass feed port of the heat exchanger through a second transfer pump, and a shell pass discharge port of the heat exchanger is connected with a tertiary butanol gas inlet of the supergravity reactor. And a discharge port of the supergravity reactor is connected with a feed port of the film evaporator. The high-efficiency mass transfer and mixing process of the supergravity reactor improves the reaction rate, can save a large amount of energy, and has the advantages of more uniform reactants and better reaction effect. The device adopts liquid sodium as a raw material to replace traditional solid sodium, the raw material is purer, the total alkali content of the product is higher, and the free alkali content is lower. The device adopts the film evaporator for drying, is simple in process operation, small in occupied space and high in efficiency, and can achieve continuous production of drying while reacting.

This invention provides a molded catalyst for the selective oxidation of isobutylene / tert-butanol and its preparation method. The molded catalyst comprises an active component and a hydroxysilicate, wherein the active component includes a molybdenum-bismuth-based composite metal oxide. In the catalyst preparation process, this invention improves the mechanical strength of the molded catalyst body after pore-expansion treatment by adding layered hydroxysilicates as a lubricant and reinforcing agent, resulting in a structurally stable molded body. This catalyst can selectively catalyze the selective oxidation of isobutylene / tert-butanol to produce valuable products with high selectivity.

The invention discloses a method for preparing bacterial nanocellulose from animal slaughtering tail water, and relates to the technical field of biological manufacturing. The method comprises the following steps: carrying out centrifugation, alkaline proteolysis, inactivation and membrane filtration pretreatment on the animal slaughter tail water to obtain a filtrate; mixing the filtrate, a glucose solution and absolute ethyl alcohol under a sterile condition, inoculating acetobacter xylinum, and carrying out static culture to obtain a bacterial cellulose wet film; performing soda boiling purification and high-pressure microjet homogenization treatment on the wet film to obtain bacterial nano cellulose aqueous dispersion; the preparation method comprises the following steps: carrying out surface grafting on bacterial nano cellulose and nano TiO2 through a silane coupling agent to introduce double bonds, carrying out ternary free radical copolymerization with a dodecafluoroheptyl methacrylate monomer, and carrying out tertiary butanol replacement and freeze drying to prepare the bacterial nano cellulose material. According to the method, high-value utilization of slaughter tail water is achieved, and the hydrophobicity and swelling resistance of the product are effectively improved through surface chemical modification.

This invention discloses a method for synthesizing α-hydroxycarboxylic acid compounds. The method includes the following steps: adding a reaction substrate, a photosensitizer, and a base to a dry reaction tube; then adding a solvent and additives under a CO2 atmosphere; and reacting under visible light irradiation. After the reaction is complete, the reaction system is acidified and quenched, and then purified to obtain the product, the α-hydroxycarboxylic acid compound. The photosensitizer includes Ir(ppy)2(dtbbpy)PF6 and 3DPA2FBN; the base is potassium tert-butoxide, cesium carbonate, or potassium tert-valerate; the additives are N,N-diisopropylethylamine and chlorosilane; and the reaction substrate is an aldehyde or ketone compound. This invention provides a highly efficient and selective synthesis of α-hydroxycarboxylic acid compounds under visible light induction and a CO2 atmosphere. The reaction conditions of this invention are mild, the reactant range is broad, the selectivity is good, and it can be scaled up to the gram scale.

The application relates to the technical field of synthesis of carbon nitride flame-retardant materials, and particularly discloses a synthesis method of melam, which comprises the following steps: taking cyanuric chloride as raw material, carrying out ammoniation and coupling to obtain a double-triazine intermediate, and then carrying out sealed ammoniation with ammonia water to obtain melam; and preferably, potassium tert-butylate is used to make the second step reaction obtain BDCAT with a yield of more than 60%; and the third step uses an ammonia water ammoniation process which is relatively safe; the synthesis method is simple, efficient, and avoids the harsh requirements of high-temperature and high-pressure methods on equipment.

The application relates to the technical field of amide preparation, and discloses a method for preparing amide through photocatalytic oxidation and amination. The method comprises the following steps: under visible light irradiation, a nitrogen source is reacted with a hydrocarbon compound in the presence of a photocatalyst and an additive, and after post-treatment, amide is obtained; wherein the photocatalyst is a photoactive carbazole compound; the additive comprises alkaline substances and acidic substances; and the hydrocarbon compound is selected from one or more of C3-C11 chain alkanes, C3-C11 cycloalkanes and C3-C11 alkyl-substituted aromatic hydrocarbons. According to the method, a C-C bond in a low or medium hydrocarbon compound is directly oxidized and aminated to break and synthesize chain amide or lactam through photocatalysis. The method has mild reaction conditions, avoids the use of a high-pressure mercury lamp or other ultraviolet lamps, avoids the generation of tar and coke under ultraviolet conditions, and avoids the use of a large amount of alcohol additives such as t-butyl alcohol.

This invention discloses a novel method for preparing 8-(2-hydroxybenzamido)octanoic acid in the field of biomedical technology. The method uses 2-hydroxybenzaldehyde and 8-aminooctaldehyde as raw materials, chloroform as solvent, and tert-butanol peroxide as oxidant, to prepare 8-(2-hydroxybenzamido)octanoic acid via an oxidation-free radical reaction. The route provided by this invention is concise, the conditions are mild, and the product yield is high, offering a general new method for the preparation of 8-(2-hydroxybenzamido)octanoic acid.