New method for preparing liposome

A liposome and new method technology, applied in the field of biomedicine, can solve the problems of loss of drug activity, increased toxicity of preparations, complicated production process, etc.
CN1444927AInactive Publication Date: 2003-10-01SHENYANG PHARMA UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2003-10-01
Estimated Expiration
Not applicable · inactive patent
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Abstract

A process for preparing the liposome of medicine includes such steps as dissolving the lipid in tert-butanol, dissolving the medicine in water, proportional mixing, freeze drying, and hydrating. Its advantages are simple process and high stability.
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Description

Technical field:

[0001] The invention relates to the technical field of biomedicine, in particular it is a new method for preparing liposomes. Background technique:

[0002] Liposomes are closed vesicle-like structures formed by phospholipid bilayers. Liposomes can be classified into unilamellar vesicles, multilamellar vesicles and multivesicular liposomes according to their structure. Liposomes were first discovered in 1965 by the British Bangham. Since then, it has been found that liposomes are of great value as drug carriers, so liposomes have been systematically studied.

[0003] After more than 20 years of exploration, researchers have proposed many valuable liposome preparation methods. At present, the preparation methods of liposomes can be mainly divided into four categories: 1) Based on the film dispersion method, the phospholipids used to form liposomes are dissolved in organic solvents—usually chloroform or chloroform and methanol mixture, and then remove the ...

Claims

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