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Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions

Disclosed and claimed are a method for the purification of polysaccharide-protein conjugate vaccines by ultrafiltration in a saturated solution of ammonium sulfate. The ultrafiltration method of the present invention provides an efficient, readily scalable method for removal of unbound polysaccharides from polysaccharide-protein vaccines, thereby improving the purity and consistency of the polysaccharide-protein vaccines.
Owner:AVENTIS PASTUER LTD

Method for zooming image

The present invention discloses a method for zooming image, and the method is implemented to an electronic device having a touch panel. When the touch panel of the electronic device detects that touch points on the touch panel are pressed simultaneously, and one of touch points is moved thereon, then the electronic device will determine whether to zoom in or out an image displayed on the electronic device according to the moving direction of the touch point, and determine to zoom in or out the image in a proportion according to the moving distance of the touch point. Thus, the image displayed on the electronic device can be zoomed in / out by the operation of touch points at the touch panel.
Owner:INVENTEC APPLIANCES CORP

Body cavity observation apparatus

A body cavity observation apparatus comprising:a treatment tool to be inserted into a body cavity of a subject with an insertion tool as a guide,an observation section attached to an opening of a body wall of the subject, a monitor for displaying the body cavity captured by the observation section, anda marker position-detecting device for detecting a position of a marker part applied to the treatment tool or insertion tool from an image showing the body cavity captured by the observation section; whereinthe marker position-detecting device comprises:a pixel extracting device for extracting a group of pixels in the same color as color of the marker part from the image, anda calculation device for calculating a position of the barycenter of the group of pixels as a position of the marker part.
Owner:FUJIFILM CORP

Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon

The invention is based on the discovery that certain membranes, which include side chains or molecular “brushes” having, for example, tertiary amino functional groups, can be used as highly effective filters to capture viruses / virus particles from liquids without removal of proteins. New methods based on this discovery include removing viruses from liquids such as blood or plasma, removing viruses from pharmaceuticals, concentrating and / or purifying viruses, e.g., for use in gene therapy, and producing recombinant viruses in new bioreactors. The invention also includes new methods of therapy or adjunct therapy for viral infections, in which a patient's blood or plasma is filtered through the membranes to remove viruses to reduce the viral load. The invention also includes new bioreactors and viral filters containing the membranes.
Owner:THE GENERAL HOSPITAL CORP

Nucleic acid amplification method

InactiveUS20050136443A1Low complementaritySpecificity of PCR is improvedMicrobiological testing/measurementRecombinant DNA-technologyA-DNAThermus thermophilus
A DNA amplification method of amplifying DNA by PCR comprises a process of preparing a mixed solution for PCR reaction by mixing a template DNA, a primer DNA, a RecA protein derived from Thermus thermophilus (T. th. RecA protein) and a phage T4 gene 32 protein, and a process of amplifying DNA by subjecting the prepared mixed solution for PCR reaction to PCR reaction.
Owner:AISIN SEIKI KK

Composite material containing modified basalt fiber and polymer and preparation method thereof

The invention provides composite material containing a modified basalt and a polymer and a preparation method thereof, wherein the main components of the composite material contains: 1200-1300 parts of polymer, 700-800 parts of modified basalt fiber, and 5-50 parts of surfactant coupling agent. The method, by means of the mechanical force, supersonic wave and electromagnetic force synthetic effect of the surfactant or coupling agent, comprises: uniformly dispersing the polymer and the modified basalt fiber into a solvent to prepare a uniform and stabile mixture, adding another solvent into the mixture, implementing the cladding or wrapping to the modified basalt fiber while precipitating the polymer from the mixture, and then forming the composite material of the modified basalt fiber containing polymer. The composite material can be used for preparing asphalt with excellent performances, the method has the advantages of low cost, simple operation and easy enlargement, and the method makes it easy for the modified basalt fiber to be uniformly dispersed in the polymer.
Owner:长沙北美孚新材料科技有限公司

Mobile phone application program window mode displaying and operating method

The invention discloses a mobile phone application program window mode displaying and operating method. The method comprises the steps of calling out a multi-window sidebar containing a plurality of application program icons on a mobile phone screen, choosing the application program icon to be operated in the multi-window sidebar, operating the chosen application program icon to call out an application program window mode corresponding to the chosen application program icon and operating an application program window. By means of the mobile phone application program window mode displaying and operating method, a user can quickly and conveniently process a third part application program in the short time through a small screen window mode.
Owner:GUANGDONG OPPO MOBILE TELECOMM CORP LTD

Method for preparing length-diameter-ratio nano-silver wire by pH-value regulation solvothermal method

The invention relates to a method for preparing a length-diameter-ratio nano-silver wire by a pH-value regulation solvothermal method. The method comprises the following steps of: preparing the following ethylene glycol solution, namely an ethylene glycol solution A of silver nitrate or silver acetate, an ethylene glycol solution B of polyvinyl pyrrolidone (PVP), an ethylene glycol solution C of water-soluble chloride and concentrated acid D; mixing the components according to a certain amount and fully stirring to form a final mixed solution; moving the final mixed solution into a reaction kettle; placing in an oven for reaction for a certain time; taking the reaction kettle out and cooling to room temperature to obtain mother liquid of the nano-silver wire; adding alcohol into the mother liquid for diluting, and removing supernatant liquor to obtain a precipitate; and repeatedly performing centrifugal separation, and thus obtaining nano-silver wire dispersion liquid uniformly dispersed in the alcohol. The method is simple, high in efficiency and low in cost, and can prepare high-quality nano-silver wires within a wider range of reaction condition; and prepared products are high in length-diameter ratio, good in length uniformity and low in impurity content.
Owner:JIANGSU NANOWELL ADVANCED MATERIALS SCI&TECH

Plasma method for preparing nano carbon material using coal liquefied residue as raw material

The invention discloses an arc plasma torch preparing nanometer charcoal fibrous material method, which comprises the following steps: placing untreated leavings of liquefying coal directly in direct current arc plasma torch to carry on heat-treatment; using nitrogen for arc working gas under atmosphere pressure; getting nanometer charcoal fibrous material after 120-175 seconds, wherein there is no need to add in any activators in preparing process. The method is characterized by the following: the craft route is simple; the raw material is the waste of coal hydrogenant liquefaction craft; it's a good way to use coal liquification leavings to prepare high-added value, functional carbon material; the nanometer charcoal fibrous material can be used for accelerating agent, catalyst carrier, lithium ion secondary cell anode material, double-layer capacitor electrode, highly effective active solid, release agent and construction reinforced materials.
Owner:DALIAN UNIV OF TECH

Method for Controlling the Display of a Touch Screen, User Interface of the Touch Screen, and an Electronic Device using The Same

A method for controlling a display of a touch screen, a user interface of the touch screen, and an electronic device using the same are disclosed. The method comprises: displaying at least one mode selection on the display of the touch screen, wherein each one of the at least one mode selections corresponds to a gesture control mode; receiving a selection command for selecting one of the at least one mode selections; entering the gesture control mode corresponding to the selected mode selection; receiving a gesture control command adapted for the entered gesture control mode; and executing a specific operation according to the gesture control command.
Owner:ACER INC

Camera snubber assembly

A method and system for limiting the motion of components such as the optics of a camera are disclosed. The system can comprise a stage and a snubber assembly for controlling motion of the stage in six degrees of freedom. For example, the snubber assembly can permit movement in one translational degree of freedom while substantially limiting motion in the other five degrees of motion so as to facilitate focusing and / or zooming of a camera while inhibiting misalignment of the optics and while providing some protection against shock and vibration. Such motion control can be achieved while mitigating costs associated with precision manufacturing of the snubber assembly.
Owner:DIGITALPTICS MEMS

Method and device for simultaneously measuring droplet position, particle sizes and complex refractive index

The invention relates to technology for simultaneously measuring multi-phase flow particles online through multi-parameter, and aims to provide a method and a device for simultaneously measuring droplet positions, particle sizes and a complex refractive index. The method comprises the following steps of: (1) dividing a highly coherent continuous laser beam into two beams after spatial filtering and collimating beam expansion, wherein one beam radiates particles in a detected flow field region, and the other beam is used as a reference beam; (2) mixing scattered light of a lateral 30-degree to 90-degree region of particles in the detected flow field region and the attenuated reference beam to perform interference so as to form a hologram, storing the hologram in a computer after being recorded by a digital camera through an imaging device; (3) acquiring a series of reconstructed images of the detected particles along the depth direction by utilizing digital reconstruction technology; and (4) identifying the reflective spot and the refractive spot of the particles from the reconstructed images by utilizing digital image processing technology so as to acquire space coordinates and scattered light intensity ratios. Compared with rainbow measurement technology, the measurement method has the advantages that: a light path system of the measurement device is relatively simple and is easy to implement.
Owner:ZHEJIANG UNIV

Asymmetrical Adapters And Methods Of Use Thereof

A pair of asymmetrical, partially double-stranded oligonucleotide adapters are provided wherein the pair of adapters comprise a first asymmetrical oligonucleotide adapter comprising a single-stranded 3′ overhang and a second asymmetrical double-stranded oligonucleotide adapter comprising a single-stranded 5′ overhang and at least one blocking group on the strand of said second asymmetrical oligonucleotide adapter that does not comprise the 5′ overhang. Also provided are a pair of double-stranded Y oligonucleotide adapters and a pair of double-stranded bubble oligonucleotide adapters and methods of using said asymmetrical adapters for amplification of at least one double stranded nucleic acid molecule, wherein the amplification produces a plurality of amplified nucleic acid molecules having a different nucleic acid sequence at each end are also described. Also provided is a method for exponentially amplifying one strand in a double-stranded nucleic acid molecule. Also provided are methods for preparing libraries of paired tags using COS-linkers. Also provided are cleavable adapters comprising an affinity tag and a cleavable linkage, wherein cleaving the cleavable linkage produces two complementary ends. Methods of using the cleavable adapters to produce a paired tag library are also described.
Owner:LIFE TECH CORP

Spherical porous silicon/carbon composite material as well as preparation method and application thereof

The invention discloses a spherical porous silicon / carbon composite material as well as a preparation method and application thereof. The spherical porous silicon / carbon composite material is structurally characterized in that a SiOx / C matrix, graphite with small particle size and a conductive agent are dispersed in porous amorphous carbon, wherein the average particle diameter is 12-25mu m; the method comprises the following steps of carrying out first coating on a SiOx raw material with powder pitch, and performing heat treatment so as to obtain a SiOx / C material; then performing ball milling by use of a wet method so as to reduce the particle diameter of powder, adding a carbon source adhesive, the graphite with the small particle diameter and the conductive agent, and performing high-speed dispersion, thereby obtaining pulp; and finally performing spray granulation and sintering on the pulp, thereby obtaining the final spherical porous silicon / carbon composite material. According to the invention, SiOx is dispersed in cracking carbon, the graphite and the conductive agent, so that SiOx volume expansion during a charge / discharge process is buffered, and the conductibility is enhanced; by virtue of the porous structure, the imbibition rate and cycle performance of the material can be effectively improved; by virtue of bitumencarb coating and high-heat treatment performed in advance, SiOx is prevented from being directly contacted with an electrolyte, and furthermore, the stability and first efficiency of the silicon / carbon material are improved.
Owner:ZHONGTIAN ENERGY STORAGE TECH

Controllable crystalline form titanium dioxide and graphite alkene composite material with high efficient photoelectricity activity and preparation method thereof

The invention discloses controllable crystalline form titanium dioxide and a graphite alkene composite material with high efficient photoelectricity activity and a preparation method thereof. The composite material is formed by mixing TiO2 powder and graphite alkene or scattering the TiO2 powder in oxidized graphite alkene dispersing agents to perform hydro-thermal reaction. The mass ratio of TiO2 powder and graphite or graphite alkene is 1:1 to 500:1. The preparation method is simple, low in cost and environmental-friendly. The controllable crystalline form titanium dioxide and a graphite alkene composite material with high efficient photoelectricity activity can control crystalline form of the obtained TiO2 according to the ratio of alcohol and water or amount of titanium sources. When the amount is amplified, the controllable crystalline form titanium dioxide and a graphite alkene composite material with high efficient photoelectricity activity have good performances. After the graphite alkene is composed, photocatalysis is greatly improved. All obtained products are applied to fields of dye sensitization solar cells, catalysts, lithium ion cells, sensing and the like.
Owner:NANJING UNIV OF TECH

Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes

Methods for preparing cell lines that contain plant artificial chromosomes, methods for preparation of plant artificial chromosomes, methods for targeted insertion of heterologous DNA into plant artificial chromosomes, and methods for delivery of plant chromosomes to selected cells and tissues are provided. In particular, plant artificial chromosomes that are substantially composed of repeated nucleic acid units of varying amounts of heterochromafin and euchromatin are provided. Also provided are methods of using plant and animal artificial chromosomes in the production of valuable transgenic plants. Methods for identifying plant genes encoding particular traits using artificial chromosomes and for producing an acrocentric plant chromosome also are provided.
Owner:CALYX BIO VENTURES +1

Catalyst used for methanation of carbon dioxide, preparation method therefor and applications thereof

The invention provides a catalyst used for methanation of carbon dioxide, a preparation method therefor and applications thereof. The catalyst employs precious metal Ru or Rh as a main catalytic activity component, employs one or more selected from elements of the I and II main groups and the II, III and VII subgroups as auxiliary agents, and employs one or more selected from SiO2, TiO2, Al2O3, CeO2 and ZrO2 as carriers. The above catalyst is used in graininess or the carriers, the auxiliary agents and the activity component are subjected to coating (wall loading) on a whole structural catalyst and metal honeycombs. The catalyst has characteristics of high activity and selectivity and wide temperature and pressure operation windows. The catalyst can be used for hydrogenation methanation removal of CO2 in a space station, then generated H2O is subjected to electrolysis, and circulation supply of oxygen is achieved. The catalyst also can be used for processes of other CO2 conversion utilization of coal-made natural gases and process gases and the like and new energy development and energy saving and emission reduction are achieved.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Preparation method of polymer porous membrane for removing water pollutants

The invention relates to the technical field of separation membranes and discloses a preparation method of a polymer porous membrane for removing water pollutants. The preparation method comprises the following steps of blending cyclodextrin and a membrane preparation material, and adding a cross-linking agent into the mixture to fix the cyclodextrin to the membrane material so that repeated use is avoided, cyclodextrin is lost from the polymer porous membrane, a selective separation function of the polymer porous membrane is lost and polymer porous membrane hydrophility is changed. The polymer porous membrane has a substantial capability of adsorption and removal of organic pollutants such as phenols and aromatic amines (aromatic substances) in water, has good heavy metal ion removal effects, has high separation efficiency and low pressure drop, is convenient for regeneration, can be massively produced and used easily, and can be widely used in an ecological protection water purification treatment system and a water treatment system.
Owner:CHINA PETROLEUM & CHEM CORP +1

Method for preparing activated carbon by utilizing direct coal liquefaction residue

InactiveCN102153081AExpand sourceImprove coal liquefaction technologySolid waste disposalAcid washingCarbonization
The invention provides a method for preparing activated carbon by utilizing direct coal liquefaction residue as a raw material. The method includes the steps as follows: (1) adding smashed direct coal liquefaction residue together with KNO3, KOH and absolute alcohol into water, stirring to be uniform under room temperature, and later drying the obtained mixture to obtain a dry material; (2) placing the prepared dry material in a carbonization furnace, conducting preoxidation in the atmosphere of air, conducting carbonization-activation in the atmosphere of inertia gas, and then obtaining coarse activated carbon; and (3) acid-washing and deashing the prepared coarse activated carbon to obtain finished activated carbon. The method is simple in preparation process route, uses conventional equipment and has universality to the raw material. The obtained activated carbon has not only characteristics of high specific surface area, developed micropores and low ash content, but also controllable output, higher productivity, suitability for production in batches, and better technological and economic benefits.
Owner:CHNA ENERGY INVESTMENT CORP LTD +2

Nucleic acid detection

ActiveUS20100227320A1Rapid and sensitive detectionRapid and sensitive and improved enrichment and detectionMicrobiological testing/measurementFermentationNucleic acid detectionNucleotide
This invention provides methods and kits for enriching and / or detecting a nucleic acid with at least one variant nucleotide from a nucleic acid population in a sample. Methods employ the use of enriching primers and bridge-probes for enriching and detecting target nucleic acids. Extension of the enriching primer permits amplification of the target nucleic acid having the variant nucleotide.
Owner:360 GENOMICS

Flexible lithium ion battery black phosphorus nanosheet-graphene composite film anode, and preparation thereof

The invention belongs to the field of electrochemistry battery, and more specifically relates to a black phosphorus nanosheet-graphene composite film anode used for flexible lithium ion batteries, and a preparation method thereof. According to the preparation method, high purity and large scale black phosphorus blocks are synthesized via mineral substance assistant vapor transporting method with high efficiency; a large amount of clean and high quality black phosphorus sheets are prepared in water via ultrasound treatment; the clean and high quality black phosphorus sheets and high conductive graphene nanosheets prepared via intercalation stripping method are subjected to mixing ultrasonic dispersion; and flexible high-strength laminated composite film is prepared via vacuum filtration. The preparation process of the flexible high-strength laminated composite film is simple and controllable; large scale low cost preparation can be realized; black phosphorus nanosheets are high in capacity, graphene is high in electrical conductivity, and the black phosphorus nanosheets and graphene both possess two-dimensional structures high in flexibility and strength, so that problems the black phosphorus is poor in electrical conductivity and stability are solved, lithium ion battery capacity, cycling stability, and entire energy density are increased, and lithium ion battery electrode integrated flexible design is realized.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI +1

Method for preparing nanometer carbon fiber/foam coal through taking coal liquefaction residues as raw materials

The method for preparing nanometer carbon fiber / foam coal through taking coal liquefaction residues as raw materials belongs to the scientific and technological field of coal materials of the scientific and technological branch of inorganic non-metallic materials. The method takes the coal liquefaction residues as the coal source of the foam coal, and compounds metallic / foam coal compound materials through the supercritical foaming method or the formwork method, and prepares the nanometer carbon fiber / foam coal compound materials through the chemical vapor deposition of organic matter. The method fully utilizes the characteristics of metallic accelerating agent containing abundant coal organic matter, iron-contained compound and the like in the coal liquefaction residues, and prepares metallic / foam coal compound materials, and the nanometer carbon fiber completely covers on the surface of the foam coal after the chemical vapor deposition. The novel nanometer carbon fiber / foam compound materials have the structural characteristics of solid foam and hollow nanometer carbon fiber. And the method is expected to be used in the fields of catalyzer and a catalyzer carrier, a fuel battery electrode material, high-effective sorbent of a fixed bed reactor and the like.
Owner:DALIAN UNIV OF TECH

Apparatus and method for preparing microparticles

Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.
Owner:ALKERMES INC

Synthesis method of noble metal nano particles

The invention discloses a synthesis method of noble metal nano particles, which comprises the following steps: dissolving soluble noble metal salt and surfactant polyvinyl pyrrolidone in ethanol at room temperature, wherein the mass ratio of the noble metal salt to the polyvinyl pyrrolidone is (1:5)-(1:20); adding a reductive amount of NaBH4, and then adding n-dodecanethiol; and carrying out centrifugal separation, precipitating, and washing to obtain the noble metal nano particles. By using ethanol as the solvent, the invention is safe, environment-friendly, green and non-poisonous, thereby reducing the environmental pollution and the harm to a human body, and being beneficial to environmental protection; the synthesis process is completed at room temperature without any heating step, thereby saving the energy and ensuring that the whole preparation process is very simple and convenient; and no special equipment is required, and the process is high in repeatability, thereby being beneficial to realizing large-scale production.
Owner:NORTHWEST UNIV

Mesoporous graphene foam as well as preparation method thereof

The invention belongs to the technical fields of a novel material as well as preparation, and particularly relates to mesoporous graphene foam as well as a preparation method thereof. The invention realizes hydrothermal preparation of a magnesium oxide texture structure and preparation of the mesoporous graphene foam by using textured magnesium oxide as a template. The mesoporous graphene foam material has abundant mesoporous structures and excellent electric property and can be used as an electrode material of batteries and supercapacitors, so that the energy density and the power density of the batteries or the supercapacitors are expectedly improved to a great extent. The cycling stability of the mesoporous graphene foam material is increased, and the mesoporous graphene foam material combined with materials with high draw ratio or the mesoporous graphene foam material can soften energy storage apparatuses. The advantages have important meaning for realization of commercialization of a new generation of energy storage apparatuses for electromobiles and development of smaller, lighter and flexible portable mobile power supplies. The business prospect is wide. Meanwhile, preparation processes of the high temperature hydrothermal method and a fluidized bed can realize engineering enlargement, so that the method is expected to be industrialized.
Owner:TSINGHUA UNIV

Method and device for preparing low-tar combustible gas through biomass gasification

ActiveCN101906323AHigh cracking rateMake up for the problem of low conduction rateGranular/pulverulent flues gasificationFixed bedCombustible gas
The invention discloses a method and a device for preparing a low-tar combustible gas through biomass gasification. The method comprises the followings steps of: pulverizing and gasifying biomass, and rapidly separating obtained gasification gas products and biomass char; heating and activating the biomass char in a microwave field; catalytically cracking tar in the gasification gas products by introducing the gasification gas products to pass through a treated biomass char layer, and carrying out secondary reaction on the gasification gas and the biomass char to produce the combustible gas. The device comprises a spiral-flow gasifier 1, a fixed bed reactor 2 and a microwave generator 3 which are connected through ducts, and the middle part of the fixed bed reactor is connected with the microwave generator 3 through a microwave duct 11. The microwave technology is applied to tar cracking, so that the problem of low heat transfer speed due to porous and loose biomass char is solved. Meanwhile, the cracking rate of tar and the secondary reaction activity between the char and the gasification gas are increased by using the 'hot spot effect' of microwaves. The device has the advantages of strong adaptability, simple and compact structure and easy enlargement.
Owner:GUANGZHOU INST OF ENERGY CONVERSION - CHINESE ACAD OF SCI
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