Process for preparing high purity mangiferin

A mangiferin and preparation process technology, which is applied in the field of preparing mangiferin with a purity ≥ 90%, can solve problems such as harmful solvent residues, achieve the effects of expanding production scale, easy process amplification, and avoiding harmful organic solvent residues

Inactive Publication Date: 2006-10-11
广西中医学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The extraction (extraction) methods of the above-mentioned three kinds of mangiferin mainly use liquids such as water, n-ethane, alcohol, dioxymethane, petroleum ether, benzene, ether, and solvent gasoline as extraction solvents, and the result is often other impurities It is extracted together with mangiferin, which requires a post-processing (refining) process; in addition, these processes also have problems such as harmful solvent residues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Fresh mango leaves are dried in the sun, removed impurities, chopped or crushed into coarse powder, extracted twice with 40% ethanol aqueous solution under reflux, each time 10 times the amount × 2 hours, combined extracts, cooled to room temperature, first applied to D101 column, and then Put it on a D900 column, collect the effluent, recover ethanol, and obtain the crude mangiferin. The crude product is heated and dissolved with 55% ethanol, filtered while it is hot, and the filtrate is cooled to room temperature, and the refined mangiferin is precipitated, and the purity of the mangiferin is over 90%.

Embodiment 2

[0018] Fresh almond leaves, dried in the sun, crushed into coarse powder, reflux extracted twice with 55% ethanol aqueous solution, 12 times the amount × 1.5 hours each time, combined extracts, cooled to room temperature, first applied to D101 column, then D301 column, collect the effluent, recover ethanol, and obtain crude mangiferin. The crude product is heated and dissolved with 65% ethanol, the ethanol is recovered and most of the water is evaporated, and the mangiferin is precipitated. This is repeated twice, and the purity of the obtained mangiferin is over 90%.

Embodiment 3

[0020] Dried almond leaves were beaten into coarse powder, refluxed with 65% methanol water and extracted twice, each time 12 times the amount × 2 hours, combined extracts, cooled to room temperature, first D101 column, then D296 column, collected effluent, recovered ethanol to obtain crude mangiferin. The crude product is heated and dissolved with 75% ethanol, the ethanol is recovered and most of the water is evaporated, and the mangiferin is precipitated. This is repeated twice, and the purity of the obtained mangiferin is over 90%.

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Abstract

The invention relates to a process for preparing high purity mango glycosides by using mango leaf or amygdale leaf as the raw material through resin method decolorization. The extracted mango glycosides has a purity higher than 90%.

Description

technical field [0001] The invention relates to a method for preparing mangiferin with a purity ≥ 90%. The process includes several key processes such as alcohol extraction, macroporous resin decolorization, and refining. Background technique [0002] Mangoes and almonds are delicious and nutritious tropical fruits. With the general improvement of people's lives, the planting area is increasing. Especially for mango, for more than 20 years, my country's Guangxi, Guangdong, Hainan, Yunnan and other provinces have continuously introduced and cultivated new varieties, making my country a big mango producer. Guangxi's mango tree planting area exceeds 100,000 hectares, and almond tree planting area is 50,000 hectares. Therefore, the number of mango and almond leaves is also large. Every year, tens of millions of tons of leaves are produced by pruning and weeding out fruit trees. In the past, fruit farmers generally treated mango leaves and almond leaves by burning them as firewo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H17/04
Inventor 邓家刚李学坚王勤
Owner 广西中医学院
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