The invention discloses an integral demodulation method of MF-TDMA non-uniform multi-carriers, and relates to related technologies such as filtering, extraction, digital reconstruction, and modulation and demodulation of digital signal processing in a communication field. Different from an integral demodulation method of uniform channel branches based on a multi-phase filter group, the non-uniform channelization technology based on a total reconstruction modulation filter group is adopted, and flexible reconstruction and integral demodulation of non-uniform TDMA signals with multi-path different symbol rates at any frequency point can be realized in a certain bandwidth by means of processing of an analysis filter, a comprehensive filter and the like. According to the invention, the integral demodulation of the non-uniform multi-path TDMA signals in an FPGA is realized, the number of processing paths is larger, the realization complexity is low, and the cost of a central station demodulator is lowered; in addition, when the method is applied to a central station of a large-capacity TDMA satellite communication system, the system is more flexible in networking processing mode, is higher in processing capability and is compatible with a uniform multi-carrier integral demodulation function.