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A medical diagnostic instrument includes a housing containing at least one battery and a light source, such as a lamp, for illuminating a medical target. A switch includes a movable member that selectively moves at least one of the battery and the lamp into and out of electrical connection with the other. The instrument is preferably fabricated from a diecast or an extrusion process wherein a thin plastic sleeve member having text and/or graphic materials can be shrink fitted onto an extruded handle.

The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or pathogen infected cells in order to treat and/or eradicate the infection. In particular, the present invention relates to toxic agents which target bacteria at different stages of the bacterial life cycle, which are delivered alone or in combination to bacteria or bacteria-infected cells. The invention relates to toxic agents which are lethal to diseased cells and methods for targeting such toxic agents to a diseased cell in order to treat and/or eradicate the disease. The present invention relates to promoter elements which are pathogen-specific or tissue-specific and the use of such promoter elements to achieve pathogen-specific or tissue-specific expression of the toxic agent(s) and/or ribozyme(s) of the present invention. Specifically, the invention relates to the delivery of one or more toxic gene products, antisense RNAs, or ribozymes, or combination thereof. The invention provides a novel system by which multiple pathogenic targets may be simultaneously targeted to cause the death of a pathogen, or cell infected with a pathogen. Further, the invention has important implications in the eradication of drug-resistant bacterium and bacterial pathogens. The invention provides a novel system by which multiple targets may be simultaneously targeted to cause the death of a diseased cell. The invention also has important implications in the eradication of drug-resistant pathogens and drug-resistant diseased cells (such as cancer cells).

Methods and apparatuses that generate a subtopic identifier identifying a client application within a client device that can support multiple users are described. The client application may be associated with a server application hosted in one or more application servers. Notification services may be registered with the application servers from the client application to forward identifiers associated with the client application for one of the multiple users to the server application to enable the server application to push notification messages to the client device selectively for the client application for that user. When receiving a notification message from the application server, the notification message may be examined to forward the notification message directly to the client application for that user without invoking other applications in the client device if the notification message carries a subtopic identifier of the client application.

A Digital Design Method which may be automated is for obtaining timing closure in the design of large, complex, high-performance digital integrated circuits. The methodincludes the use of a tuner on random logic macros that adjusts transistor sizes in a continuous domain. To accommodate this tuning, logic gates are mapped to parameterized cells for the tuning and then back to fixed gates after the tuning. Tuning is constrained in such a way as to minimize “binning errors” when the design is mapped back to fixed cells. Further, the critical sections of the circuit are marked in order to make the optimization more effective and to fit within the problem-size constraints of the tuner. A specially formulated objective function is employed during the tuning to promote faster global timing convergence, despite possibly incorrect initial timing budgets. The specially formulated objective function targets all paths that are failing timing, with appropriate weighting, rather than just targeting the most critical path. Finally, the addition of multiple threshold voltage gates allows for increased performance while limiting leakage power.

Parental control rules are logically separated from a set of parental control effects. Control rules are responsive to detectible circumstances, including: business relationships between the DVD owner and its content owner, particular presentation location or device, actual viewers present, date or time. Control effects include ways to edit or suppress inappropriate content, including: defacing via sound or video blanking, skipping scenes, presenting alternative scenes, warning of inappropriate scenes, and similar behavior for associated metadata.

Methods and system for providing companion content at a secondary device for a content being rendered on a main device includes establishing a connection between the secondary device and a device that interfaces with the main device so as to enable the secondary device to access and control the content being rendered on the main device. The method further includes detecting data associated with the content being rendered on the main device through the connection, wherein the data includes metadata associated with the content rendered on the main device. The metadata is communicated to a remote application over the internet. The remote application is configured to analyze the metadata to produce communication content that relates to the content rendered on the main device. Companion content for the content being rendered on the main device is obtained from the remote application and rendered on the secondary device while the content is rendering on the main device. The analysis of the metadata detects changes in the content being rendered on the main device which results changes in the obtained companion content that is rendered on the secondary device.

A database management and synchronization program implemented across a peer-to-peer computer network, consisting of a sharing community of user computers. Database record synchronization throughout the sharing community is accomplished by using a synchronization object which contains the information about a change in a specific record or the addition of a new record. The synchronization object is transmitted by a local user computer at any time to a routing agent, which in turn transmits the synchronization object at any time to remote user computers within the sharing community. The synchronization object is then used by the remote user computer to update their database records.

System and method for repeater in a power line network. According to an embodiment, the present invention provides a method for power line communication network. The method includes providing a virtual local area network (VLAN), which VLAN includes at least a repeater, a client, and a gateway. The VLAN is associated with a network encryption key. The repeater is associated with a first identification. The client is associated with a second identification. The gateway is associated with a third identification. The first identification and the third identification are a service identification type. The second identification is a client identification type. The method also includes providing a power line network that is configured to transmit data through OFDM signaling. The method includes sending a first data packet in first format from the client through the power line network. The method additionally includes receiving the first data packet by the repeater through the power line network at through a first network interface.

A cloud service brokerage system includes an electronic cloud service catalog containing cloud service defining information for a plurality of cloud services and a cloud service store coupled to the electronic cloud service catalog. The cloud service store includes cloud service publications each representing cloud service functionality corresponding to one or more of the cloud services. The cloud service store includes a user interface structure enabling generation of cloud service orders each including one or more of the cloud service publications.

A bone conducting headset apparatus (10) that includes a pair of speaker/microphone members (30) (30) mounted at the juncture of a head strap (21) and a neck strap (22) provided with a spring biasing member (23) wherein, the speaker/microphone members (30) (30) are operatively connected to an electronic control member (40) that is provided with means (46) for selectively attaching the electronic control member (40) to a desired article of the user's clothing wherein, the electronic control member (40) is provided with PTT technology, as well as, high noise cut-off (44) directional hearing (48) (48) and selective communication features (42).

A process for utilizing microwaves to heat H₂O within a subterranean region wherein the heated H₂O contacts heavy oil in the subterranean region to lower the viscosity of the heavy oil and improve production of the heavy oil.

A suturing apparatus configured to suture an opening extending through an outer wall of the heart, such as a transapical opening, can comprise an elongate body having a proximal end, a distal end, a tapered or rounded tip, one or more arms, and one or more needles. A handle at the proximal end of the elongate body can be configured to be manipulated from outside of the heart. The elongate body can have a substantially constant outer diameter between the handle and the distal end. The arms can hold portions of suture a distance away from the outer diameter of the elongate body. The arms can be extendable from said body from a retracted position to an extended position. The arms in the extended position can point distally and form an acute angle with a longitudinal axis of the elongate body. The plurality of needles can be movable to pass through heart tissue into engagement with the suture portions held by the arms and back through the heart tissue to draw the suture portions through the heart tissue.

Systems and methods for integrated media monitoring are disclosed. The present invention enables users to analyze how a product or service is being advertised or otherwise conveyed to the general public. Via strategically placed servers, the present invention captures multiple types and sources of media for storage and analysis. Analysis includes both closed captioning analysis and human monitoring. Media search parameters are received over a network and a near real-time hit list of occurrences of the parameters are produced and presented to a requesting user. Options for previewing and purchasing matching media segments are presented, along with corresponding reports and coverage analyses. Reports indicate the effectiveness of advertising, the tonality of editorials, and other information useful to a user looking to understand how a product or service is being conveyed to the public via the media.

This invention is a Collaborative Funding Engine (the Engine) that accurately predicts initial demand for and facilitates the funding of design, research, development and/or delivery of products, and/or services (Outputs). The Engine enables one or a plurality of those (the Customers) who desire specific Outputs to combine their resources in Collaborative Funding Pools (CFPs) to fund the Outputs by an Output producer (the Provider) prior to the Output's creation. The Engine includes a Contingent Purchase Order (CPO) system that creates binding obligations on Providers and Customers contingent upon the CFP reaching a specified level (the Hurdle Level) of participation by Customers. The Engine includes an optional Relative Value Bidding feature that can allow each Customer in a CFP to determine its own price for an Output. As a result, different Customers can pay different prices for the same Output depending upon the Output's relative value to the Customer. The collaborative activity of the Engine is stimulated by its Notification Management Module, which informs Providers and Customers of activity within the Engine.

An electrosurgical pencil for delivering high frequency cutting and coagulation signals from an electrosurgical generator is disclosed. A flexible, elongated, substantially solid pencil housing is provided having a cable receiving end and a blade electrode receiving end opposed from the cable receiving end. A mechanism is provided within the pencil housing for bending of the pencil housing between the cable receiving end and the blade electrode receiving end. Additionally, a mechanism is provided within the electrosurgical pencil for retaining a bent position of the pencil housing. The electrosurgical pencil of the present design may be a foot controlled electrosurgical pencil or may include a manually actuated switch within the pencil housing to form a hand controlled electrosurgical pencil.

Advanced device for the welding training based on simulation with Augmented reality and with remote updates that allows the simulation of: all the industrial welding types—electrode stick (SMAW), MIG/MAG (GMAW, FCAW) and TIG (GTAW)—; all the materials; all the joint types and, also all the welding positions (1Fa 4F, 1G a 6G, 6GR, etc.). It offers an accurate simulation of a real welding equipment thanks to the use of the Augmented Reality technology, which allows the interaction between different elements in several layers. All this is implemented by a monitoring and student evaluating system that allows the teacher to control remotely what is happening in the classroom in real time and without the necessity of being physically present in the training.

For an apparatus effectively providing a real three-dimensional model to a customer, three-dimensional shape data of a target is obtained at a data input section (10). The data is managed by a server which is connected to a network. A suitable formation section (14) is selected to form a real three-dimensional model based on the data. In addition, the formation completion is automatically notified to the customer via a completion display panel (260), a cellular phone (61), or the like.

A combination of several analytical computer-assisted modeling techniques may be used to evaluate the value of a brand, the relative value of competitive brands and may identify the opportunities to increase brand value and the priority of those opportunities. Image/Attitudinal driver analysis, pyramid analysis, probability analysis, trade-off analysis, and other regression techniques may be used in novel combinations to quantify brand development, impacts and the overall estimate of brand value. For example: (1) image driver analysis may be applied to each level of a brand pyramid to understand how to most effectively move customers through to the next level in the pyramid; (2) probability analysis may be used to estimate the impact of each movement through the pyramid; and (3) tradeoff analysis may be used to improve the value customers perceive at any particular level of the pyramid.