42 results about "Isobutyraldehyde" patented technology

The utility model belongs to the technical field of chemical solvent preparation, and particularly relates to a tetrahydrofuran purification device. The utility model provides a tetrahydrofuran purification device. The tetrahydrofuran purification device comprises a feed port, a catalytic hydrogenation reaction part, a gas phase discharge port, a liquid phase discharge port, a heavy component removal tower and an absorption tower. In the application, through the catalytic hydrogenation part, the impurity dihydrofuran in the tetrahydrofuran is hydrogenated to generate the tetrahydrofuran, the impurities n-butyraldehyde and isobutyraldehyde are hydrogenated to generate alcohols which are easily separated from the tetrahydrofuran, through determination, the content of the impurity dihydrofuran in the purified tetrahydrofuran is reduced to 3 ppm or below, the alcohols are separated in the heavy component removal tower, and the content of the tetrahydrofuran in the tetrahydrofuran is reduced to 3 ppm or below. The purity and the quality of tetrahydrofuran are effectively improved, and the purification device structure and the purification process are simple.

This invention belongs to the field of homogeneous catalysis technology, and particularly relates to a method for the hydroformylation of propylene to prepare isobutyraldehyde. The method includes: in the presence of a bidentate P-N ligand and a rhodium metal compound, introducing propylene and syngas to carry out a hydroformylation reaction to prepare isobutyraldehyde. The structural formula of the bidentate P-N ligand is as follows: [Insert structural formula here]. Wherein, R1 is selected from one of C2-C4 alkyl groups, substituted or unsubstituted phenyl groups; R2 is selected from one of hydrogen, C1-C4 alkyl groups, alkoxy groups, substituted or unsubstituted phenyl groups. This method provides a highly active P-N ligand, which, while reducing the amount of rhodium catalyst, maintains high activity and can significantly improve the conversion rate of propylene, as well as the selectivity and yield of isobutyraldehyde.

The application relates to establishment and application of an isobutyraldehyde biosensor and belongs to the technical field of bioengineering. yqhD The RFP report system responding to isobutyraldehyde is established, the yqhC gene is rationally designed, a mutant library is constructed through random mutation by using error-prone PCR, isobutyraldehyde is used as a substrate, and through screening of response concentrations and response thresholds, a YqhC mutant without background fluorescence response, with a wider substrate detection range (0-5 g / L) and higher response intensity (24 times) is obtained, and the YqhC mutant is named YqhCm9. The isobutyraldehyde response element (YqhCm9) and the fluorescent protein report element (RFP) are used to construct a high-efficiency and specific isobutyraldehyde biosensor, real-time monitoring of an isobutyraldehyde production process and screening of an isobutyraldehyde production strain can be carried out.

The application provides a detection device for isobutyraldehyde and application and a method for detecting isobutyraldehyde, relates to the technical field of isobutyraldehyde detection, and comprises an automatic sampling part, a catalytic luminescence reactor and a detection instrument; wherein the catalytic layer of the catalytic luminescence reactor comprises nano barium titanate; the detection device has sensitive response, excellent specificity and better stability to isobutyraldehyde, achieves the technical effects of good reproducibility, rapid response, rapid recovery and repeated detection in a short time, and provides guarantee for long-term online accurate detection of the isobutyraldehyde concentration.

The utility model discloses an isobutyraldehyde dehydration and purification device, which comprises a butyraldehyde isomer separation tower, and is characterized in that the device also comprises a dehydration coalescer and a water stripping tower, mixed butyraldehyde from a stabilization tower enters the dehydration coalescer, is dehydrated by a coalescence filter element in the dehydration coalescer, and then enters the water stripping tower; mixed butyraldehyde is fed into a butyraldehyde isomer separation tower from the top of the dehydration coalescer, isobutyraldehyde at the tower top is condensed by a tower top cooler and then enters a reflux tank to be layered, wastewater is extracted from a lower-layer water phase, isobutyraldehyde is extracted from an upper-layer oil phase, and part of the isobutyraldehyde flows back to the butyraldehyde isomer separation tower; and sending the aldehyde-containing wastewater at the bottom of the dehydration coalescer to a water stripping tower. When the device is used for separating n-butyraldehyde and isobutyraldehyde, moisture in n-butyraldehyde and isobutyraldehyde can be effectively removed under various working conditions, and qualified n-butyraldehyde and isobutyraldehyde can be obtained through separation.

The present invention belongs to the technical field of catalyst preparation, and particularly relates to a bimetallic solid base catalyst for the esterification of isobutyraldehyde and furfuryl alcohol to prepare 2-furylmethyl 2-methylpropionate and its application. First, a layered double hydroxide precursor containing gold and palladium metal atoms is prepared, and then it is calcined at high temperature in a muffle furnace to destroy the ordered layered structure of the layered double hydroxide (LDHs), increasing the surface area and pore volume to obtain a mesoporous structured bimetallic solid base catalyst. The Au-Pd / MgO-Al2O3 bimetallic solid base catalyst prepared by this method can catalyze the esterification reaction of isobutyraldehyde and furfuryl alcohol to prepare 2-furylmethyl 2-methylpropionate. The catalyst preparation method of the present invention is simple, the catalyst cost is low and the stability is high, and excellent catalytic activity and selectivity are demonstrated in the esterification reaction of isobutyraldehyde and furfuryl alcohol to prepare 2-furylmethyl 2-methylpropionate.

The invention discloses a preparation method and application of a 2, 5-diketopiperazine derivative, and belongs to the field of biological medicine. The preparation method comprises the following steps: by taking 1, 4-diacetyl piperazine-2, 5-diketone (II) as an initial raw material, firstly, carrying out condensation reaction on the initial raw material and isobutyraldehyde to prepare a key intermediate (III); meanwhile, 4-amino-1-butanol (IV) is converted into an intermediate (VI) through acylation and oxidation two-step reaction; and finally, carrying out condensation and elimination reaction on the intermediates (III) and VI to prepare the target compound (I). The preparation method provided by the invention has the advantages of reasonable route design, mild conditions and outstanding stereoselectivity. According to the method, on the basis of easily available raw materials, a product mainly comprising a Z configuration is efficiently constructed through a modular strategy and consistent mild base catalysis conditions. Experimental data show that the compound prepared by the invention can inhibit TG accumulation in nematode bodies and reduce nematode fat accumulation, and can be developed into efficient medicines for preventing and treating obesity.

The utility model belongs to the technical field of neopentyl glycol production, and particularly relates to a raw material adding device for neopentyl glycol production. The device comprises a reaction tank body, the top of the reaction tank body is provided with a top cover, the bottom of the reaction tank body is provided with a discharge port, the reaction tank body is internally provided with an inner tank body, the inner tank body is provided with an atomization nozzle, and the bottom of the inner tank body is provided with an atomization mechanism; a feeding hole is formed in the reaction tank body, the feeding end of the feeding hole is connected with a first connecting pipe, and the first connecting pipe is connected with a formaldehyde tank; a discharge hole is formed in the bottom of the reaction tank body, and an adding hole is formed in the reaction tank body. Isobutyraldehyde is contained in the inner tank body, formaldehyde enters the space between the inner tank body and the reaction tank body, the atomizing machine is started, isobutyraldehyde enters the space between the inner tank body and the reaction tank body in an atomized state, other raw materials are added through the adding opening, in the reaction process, liquid dripped into the bottom in the reaction tank body is atomized through the atomizing mechanism, and formaldehyde is added into the space between the inner tank body and the reaction tank body. And the reaction is continuous and sufficient.

The invention provides a continuous preparation method and device of 5-methyl-3-hexene-2-ketone, and relates to the technical field of organic synthesis. The method comprises the following steps: continuously introducing acetone, isobutyraldehyde and a catalyst for mixing, carrying out aldol condensation reaction, continuously discharging the obtained reaction liquid containing 5-methyl-3-hexene-2-ketone, and carrying out liquid-liquid separation to respectively obtain a water phase and an organic phase; the catalyst in the water phase is recycled and reused for the aldol condensation reaction; the organic phase is subjected to rectification, and a recovery raw material and 5-methyl-3-hexene-2-ketone are obtained respectively; the recycled raw material is used for the aldol condensation reaction. According to the method provided by the invention, efficient, stable, controllable, low-energy-consumption, economical, safe and continuous industrial production of the 5-methyl-3-hexene-2-ketone can be realized. According to the invention, the temperature and the stirring speed of aldol condensation reaction are controlled to be 50-200r / min, so that the yield, the selectivity and the purity of the product are improved.

The invention relates to application of a bromoethyl pillar [5] arene crystal material as an adsorbent in n-butyraldehyde adsorption, and belongs to the technical field of adsorption separation materials. The bromoethyl pillar [5] arene crystal material is used as an adsorbent to efficiently adsorb n-butyraldehyde, the structural formula of the bromoethyl pillar [5] arene crystal material is shown in the specification, the chemical property of the bromoethyl pillar [5] arene crystal material is stable, n-butyraldehyde can be separated from gaseous butyraldehyde isomers with the purity of 99.1%, and the bromoethyl pillar [5] arene crystal material can be recycled without losing any performance. Moreover, the separation method of the butyraldehyde isomer is simple in process operation and low in equipment requirement; in addition, rectification operation is not needed, energy consumption is low, energy is saved, and the production cost of n-butyraldehyde and isobutyraldehyde is reduced.

The invention discloses a method for preparing isobutyraldehyde by catalyzing methanol and ethanol through a composite metal oxide catalyst, and particularly relates to a method for preparing isobutyraldehyde by catalyzing methanol and ethanol through an aldol condensation reaction by taking V2O5 as a main metal oxide catalyst. The introduced metal oxides comprise one or more of TiO2, Al2O3, ZrO2, SiO2, La2O3 and Nb2O5, and the composite metal oxide catalyst mainly containing V2O5 is prepared by one or more methods of mechanical grinding and is used for preparing isobutyraldehyde from methanol / ethanol. The method has the advantages that the metal oxide is introduced to optimize the oxygen supply activity and restore the oxidation capacity of the vanadium catalyst, so that the product selectivity is improved.

The invention relates to a food product having an enhanced and improved savoury and / or meaty flavour which is at least partially obtained from a seaweed concentrate or product derived therefrom wherein the food product comprises at least 3, preferably 4 and most preferred all 5 components from the group of 2-methylbutyraldehyde, 5-methylfurfural, furfural, 2(E)-decenal, and isobutyr aldehyde. Also the process is found for making a food product by combining an edible product and flavour product providing a meaty flavour to food products, and the process for making such flavour composition.

The application discloses a method for catalyzing propylene hydroformylation by using a Zn-modified Rh-based molecular sieve catalyst. The method comprises the following steps: placing the Zn-modified Rh-based molecular sieve catalyst and an organic solvent in a high-pressure reaction kettle, replacing the air in the kettle after sealing, then introducing a mixed gas, heating to 60-120 DEG C, and reacting for 0.5-2.0 h under stirring and a total pressure of 1.0-5.0 MPa to obtain n-butyraldehyde and isobutyraldehyde. In the preparation of the catalyst, ethylenediamine is used as a bimetallic complexing agent, and Rh and Zn are controllably co-encapsulated in S-1 molecular sieve crystals through a one-step hydrothermal crystallization method, and the molar ratio of Zn / Rh is continuously adjusted in a wide range of 0.25-8.9. The catalyst has excellent performance under mild reaction conditions and has a good industrial application prospect.

The present application relates to a method for separating high-purity n-butyl aldehyde from mixed butyl aldehyde of carbonyl synthesis product, comprising the following steps: adding reaction inhibitor to the product of carbonyl synthesis reaction after separating catalyst, part of which enters high-pressure rectifying column, and the other part enters low-pressure rectifying column, n-butyl aldehyde product is obtained from the side line of high-pressure rectifying column and the bottom of low-pressure rectifying column, and iso-butyl aldehyde product is obtained from the top of high / low-pressure column. The present application adds reaction inhibitor to improve product purity, solves the problem of easy polymerization of mixed butyl aldehyde by using the characteristics of low-temperature decomposition of butyl aldehyde trimer, separates high-purity n-iso-butyl aldehyde from mixed butyl aldehyde with low energy consumption, and has low equipment investment cost and can create high economic benefits.

The invention relates to the technical field of petrochemical engineering, and particularly discloses a method for co-producing butanol, octanol and neopentyl glycol, which comprises the following steps: synthesizing butyraldehyde from propylene and synthesis gas through two tower reactors under the action of a catalyst, evaporating butyraldehyde, the mixed catalyst and a ligand through a falling film evaporator, and feeding into a membrane separator; according to the method, butyraldehyde is separated from a catalyst and unreacted products in a membrane separator, butyraldehyde obtained through separation enters an n-butyraldehyde and isobutyraldehyde separation tower, isobutyraldehyde is obtained at the tower top, n-butyraldehyde is obtained at the tower kettle, methanol and air generate formaldehyde under the action of an electrolytic silver catalyst, and a 37% formaldehyde solution is obtained through two absorption towers; according to the invention, butanol, isooctanol and neopentyl glycol are integrated through equipment, and the integrated butyraldehyde reaction device, the integrated condensation reaction device and the integrated hydrogenation reaction device are adopted, so that reaction, heat removal and product separation are realized in one reactor, and the effects of saving energy, reducing consumption and saving land are achieved.

The present invention provides a process for preparing neopentyl glycol, the process comprising: feeding a feed stream comprising formaldehyde and isobutyraldehyde into an aldol reactor and subjecting the feed stream to an aldol condensation reaction in the presence of a catalyst to obtain a first reaction product comprising hydroxypivalaldehyde; feeding the first reaction product to an aldol purification column; feeding the upper discharge stream of the aldol purification column to a decanter and separating an organic phase stream comprising unreacted isobutyraldehyde and the catalyst and an aqueous phase stream comprising the catalyst salt; feeding the aqueous phase stream to a saponification reactor to reduce the catalyst salt to a catalyst and recover the catalyst; and feeding the lower discharge stream of the aldol purification column to a hydrogenation reactor and subjecting the lower discharge stream of the aldol purification column to a hydrogenation reaction to obtain neopentyl glycol.

The invention relates to the technical field of building waterproof coatings, and discloses an environment-friendly latent curing agent and a preparation method thereof, an environment-friendly polyurethane waterproof coating raw material composition, an environment-friendly polyurethane waterproof coating and a preparation method thereof. The preparation method of the environment-friendly latent curing agent comprises the following steps: (1) in the presence of a solvent, carrying out first mixing on an aldehyde compound and an amine compound to obtain an intermediate I; the aldehyde compound is a combination of an aldehyde compound I and an aldehyde compound II in a content molar ratio of (1-2.5): 1; the aldehyde compound I is benzaldehyde and / or isobutyraldehyde, and the aldehyde compound II is nonanal and / or capraldehyde; and (2) carrying out dehydration condensation reaction on the intermediate I to obtain the environment-friendly latent curing agent. The environment-friendly polyurethane waterproof coating prepared by the preparation method disclosed by the invention has better environment-friendly performance and also has good mechanical properties.

The invention discloses equipment for manufacturing isobutyric acid and a manufacturing method of isobutyric acid. The equipment for manufacturing isobutyric acid comprises a reaction tank, an air inlet pipe, an air outlet pipe and a stirrer. The gas inlet pipe is connected with the reaction tank and is used for introducing working gas into the reaction tank; and the gas outlet pipe is connected with the reaction tank and is used for guiding the reacted gas out of the reaction tank. The stirrer is arranged in the reaction tank and comprises a hollow shaft and a plurality of blades; the hollow shaft is provided with a first end and a second end which are oppositely arranged, the first end is provided with an air exhaust hole and exposed out of the liquid level of the reaction tank, and the second end is provided with an air exhaust hole and immersed in the liquid level. The other end, opposite to the reaction tank, of the gas outlet pipe is connected with the condenser so as to condense the reaction gas to obtain isobutyraldehyde and tail gas, and isobutyraldehyde can be conveyed back to the reaction tank through the pump to continue the reaction, so that the conversion rate is increased.

The utility model discloses a device for optimizing the structure of a butyl octanol product. The device is characterized in that a side line feed port of a butyraldehyde isomer tower is connected with a feed pipeline, and a tower top discharge port is respectively connected to an isobutyraldehyde hydrogenation unit and an isobutyraldehyde storage tank; a tower bottom discharge hole is connected to an n-butyraldehyde condensation unit; a gas phase extraction opening in the side wall of the tower kettle is connected to a feeding opening of an n-butyraldehyde buffer tank through a gas phase extraction pipeline, an n-butyraldehyde condenser and a first n-butyraldehyde cooler are arranged on the gas phase extraction pipeline, and a discharging opening of the n-butyraldehyde buffer tank is connected to a feeding opening of the n-butyraldehyde tank; and a discharge port of the n-butyraldehyde tank is respectively connected to the n-butyraldehyde hydrogenation unit and the n-butyraldehyde condensation unit through a first branch extraction pipeline and a second branch extraction pipeline. According to the utility model, the structure of the butanol and octanol product can be conveniently and quickly optimized, and any several of high-purity n-butyraldehyde, isobutyraldehyde, n-butyl alcohol, isobutyl alcohol and octanol can be selectively produced according to requirements.

A method for preparing neopentyl glycol, the method including: feeding a feed stream containing formaldehyde and isobutyraldehyde to an aldol reactor and subjecting the feed stream to an aldol condensation reaction in the presence of a catalyst to obtain a first reaction product containing hydroxypivaldehyde; feeding the first reaction product to an aldol purification column; feeding the aldol purification column upper discharge stream to a decanter and separating an organic phase stream containing unreacted isobutyraldehyde and the catalyst and an aqueous phase stream containing a catalyst salt; feeding the aqueous phase stream to a saponification reactor to reduce the catalyst salt to a catalyst and recover the catalyst; and feeding the aldol purification column lower discharge stream to a hydrogenation reactor and subjecting the aldol purification column lower discharge stream to a hydrogenation reaction to obtain neopentyl glycol.

The utility model discloses mixed butyraldehyde separation equipment which comprises a distillation tower, a mixed aldehyde feeding hole is formed in one end of the outer side of the distillation tower in a penetrating manner, three ends below the distillation tower are fixedly connected with a bracket, a reboiler is correspondingly arranged at the outer end of the distillation tower, a connecting pipe is arranged in the reboiler in a penetrating manner, and the connecting pipe is fixedly connected with the bracket. According to the invention, the plurality of tower plates are arranged in the distillation tower and are matched with the heating of the reboiler, so that the n-butyraldehyde in the isobutyraldehyde is gradually reduced, and the n-butyraldehyde at the tower top reaches the lowest content of isomer separation in the tower; the isobutyraldehyde can enter the isobutyraldehyde collecting box through the collecting pipe, rapid separation of the mixed butyraldehyde is completed, the circulating assembly is adopted, the isobutyraldehyde can be used as reflux liquid after being condensed, and the separation efficiency of the isobutyraldehyde is improved.

This invention relates to a method for preparing methyl isopentyl ketone, comprising the following steps: acetone and isobutyraldehyde are mixed and passed through a fixed-bed reaction section packed with a layered metal oxide condensation catalyst; acetone and isobutyraldehyde are recovered by distillation for reuse; the condensation product enters a fixed-bed hydrogenation section, where it reacts with hydrogen under the action of a hydrogenation catalyst to obtain methyl isopentyl ketone. This invention separates the key reaction steps of condensation and hydrogenation. Firstly, the condensation catalyst designed based on the aldehyde-ketone condensation mechanism has higher condensation selectivity, forming the MIAK hydrogenation precursor, thus avoiding the self-condensation reaction of acetone and isobutyraldehyde and also avoiding the conversion of acetone to alcohol.

The application discloses coffee essence, atomized liquid and electronic atomization device, and belongs to the field of electronic atomizers. The coffee essence comprises 2-acetylpyrrole, vanillin, methylcyclopentenolone, maltol, furfuryl acetate, guaiacol, isopentyl alcohol propylene glycol solution, furfuryl mercaptan, 2-ethyl-3,5-dimethylpyrazine, isovaleric acid propylene glycol solution, 2,3,5-trimethylpyrazine, isobutyraldehyde, 2-methyl-3-(methylthio)pyrazine, isoamyl aldehyde, trigonellin, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 5-methylfurfural, dimethyl sulfide, 2-acetylfuran, 5-hydroxyethyl-4-methylthiazole, 2-acetylpyrazine, 4-ethylguaiacol, acetic acid, propionic acid, acetaldehyde propylene glycol solution, 4-methyl-5-(2-acetyloxyethyl)-thiazole and propylene glycol. The coffee essence has good stability, good compatibility and can accurately restore the real coffee roasting aroma.

The invention provides a green n-isobutyraldehyde separation system and a green n-isobutyraldehyde separation method, the separation system comprises an atmospheric tower, a pressurized tower and a flow divider, and the flow divider is connected with the atmospheric tower and the pressurized tower through an atmospheric tower raw material liquid inlet and a pressurized tower raw material liquid inlet respectively. Through efficient heat recovery and unique pipeline design, the energy consumption is remarkably reduced, the separation efficiency is improved, meanwhile, the environmental pollution is reduced, and green separation of n-butyraldehyde and isobutyraldehyde is realized. Compared with the prior art, the invention has obvious progress in the aspects of energy conservation, environmental protection, separation effect and system stability.

This invention belongs to the fields of chemical material synthesis and biomedicine, and provides a method for synthesizing α-ketovaline calcium. This method uses environmentally friendly and low-cost diethyl oxalate as a raw material. The pKa value is precisely controlled through a mixed alkali system to suppress the self-condensation side reaction of isobutyraldehyde. After the condensation reaction at 55-60℃, formic acid is generated through alkaline degradation. Byproducts are completely removed using a 1:1 redox reaction of 30% hydrogen peroxide and formic acid, replacing the traditional high-energy-consuming distillation process. The product yield reaches 78.1%, and the purity is ≥99.8%, demonstrating significant advantages in terms of economy, environmental friendliness, and industrial feasibility.

The application provides a co-production device and process of isobutyraldehyde and n-butyraldehyde, and particularly relates to the technical field of olefin hydroformylation industry. The co-production device comprises a purification device, a hydroformylation device, a falling film evaporator device, a rectifying tower A, a rectifying tower B and a rectifying tower C which are sequentially connected; the bottom of the rectifying tower A is connected with the rectifying tower B; the bottom of the rectifying tower B is connected with the rectifying tower C. The co-production device realizes the production and separation of isobutyraldehyde and n-butyraldehyde simultaneously in one set of co-production device, effectively reduces energy consumption, is simple in equipment, high in production capacity and suitable for large-scale industrial production. Meanwhile, the obtained n-butyraldehyde and isobutyraldehyde products have a purity of more than 99.8 mol%, and a water content of less than 0.1 mol%, are higher in purity and meet the demand of high-end n-butyraldehyde and isobutyraldehyde products on the market.

The present application provides a hydroformylation catalyst and a method for preparing isobutyraldehyde. The hydroformylation catalyst comprises a metal compound and a phosphine-containing ligand containing specific sulfur. The method is: adding a substrate and a hydroformylation catalyst into a high-pressure reaction kettle, then introducing synthesis gas into the high-pressure reaction kettle, heating and reacting to prepare the corresponding formylation product. The catalyst has high regioselectivity, can reduce the n-iso isomer ratio of aldehyde in the product of olefin hydroformylation reaction, realize low n-iso ratio in the process of preparing butyraldehyde by propylene hydroformylation, and has high stability in the reaction.

The application provides a multi-tube parallel filling oxidizer and a preparation method of isobutyric acid, and relates to the field of preparation of isobutyric acid. In the multi-tube parallel filling oxidizer, oxygen and isobutyraldehyde are countercurrently contacted, the contact efficiency is improved, and the oxidation reaction is rapidly reacted; and on the basis of circulating cooling water, an outer circulation heat exchange system is additionally arranged, so that the temperature of reactants can be better controlled, the occurrence of a side reaction is greatly reduced, and the product purity is improved.

The invention relates to a method for separating alcohol mixtures with high water content using an extraction solvent. In particular, the present invention relates to a process for liquid-liquid extraction of a C2-C3 alcohol or a mixture of C2-C4 alcohols from a C2-C3 alcohol or a mixture of C2-C4 alcohols and water with an extraction solvent selected from the group consisting of isobutyraldehyde and n-pentane / dimethylacetal mixtures.

The application relates to the technical field of isobutyraldehyde detection, in particular to application of hydroxyapatite in detection of isobutyraldehyde. The application provides application of hydroxyapatite in detection of isobutyraldehyde, and also provides a preparation method of the hydroxyapatite. It is found that the hydroxyapatite has good responsiveness, specificity, stability and reproducibility in detection of isobutyraldehyde, and the application of the hydroxyapatite is expanded.