427 results about "Cinnamic acid" patented technology

The invention belongs to the technical field of microorganisms, and particularly relates to pseudomonas monteilii BDLZ-3 and application thereof in relieving continuous cropping obstacles of crops. The invention discloses a strain of pseudomonas monteilii BDLZ-3, the preservation number of which is CGMCC (China General Microbiological Culture Collection Center) No.34349. The pseudomonas monteilii BDLZ-3 is separated and screened from the nature for the first time, phenolic acid autotoxic substances generated in the ginseng continuous cropping obstacle process can be efficiently degraded, the degradation rate of benzoic acid can reach 95.36%, various phenolic acids such as vanillic acid, cinnamic acid, palmitic acid and gallic acid can be effectively degraded, and the degradation spectrum is wide; when the pseudomonas monteilii BDLZ-3 is applied in a field, the content of benzoic acid in soil can be effectively reduced, meanwhile, the occurrence of ginseng root diseases can be controlled to a certain extent, the prevention and treatment effect reaches 41.23%, the growth indexes such as root length and root thickness are remarkably improved, and the yield increasing effect is achieved.

The invention discloses streptomyces bulbus as well as a multifunctional fungicide and application thereof. According to the invention, firstly, a strain of Streptomyces tauricus zhanshen-LZ-12 is separated and screened from straw returning soil, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.34456. The invention also discloses a preparation method of the Streptomyces tauricus zhanshen-LZ-12. The strain has the functions of degrading cellulose, decomposing protein, fixing nitrogen, resisting salt, degrading phenolic acid autotoxic substances (benzoic acid, p-hydroxybenzoic acid and cinnamic acid) and the like. Bacterial powder obtained after fermentation of the bacterial strain is uniformly mixed with bacillus bacterial powder to obtain the multifunctional bacterial agent, and when straw returning or composting is carried out, the multifunctional bacterial agent is adopted, straw decomposition can be accelerated, soil ecology can be improved, crop growth can be promoted, and the stress resistance of crops can be enhanced.

The invention discloses fresh and wet sweet potato vermicelli and a preparation method thereof, the fresh and wet sweet potato vermicelli comprises the processing raw materials of sweet potato starch, domestic drinking water, an acidity regulator and a fresh-keeping preservative, the usage amount of the fresh-keeping preservative is 0.05-0.6% of the weight of the starch raw material, and the preparation method comprises the following steps: weighing the raw materials of the fresh and wet vermicelli, preparing starchy sauce, preparing dough, mixing slurry, curing and forming, and the like, thereby obtaining the fresh and wet sweet potato vermicelli. Aging the cured vermicelli for 1-2.5 hours in an environment of 10-1 DEG C, so as to obtain aged vermicelli; and cutting the aged vermicelli into strips, performing vacuum packaging, and performing pasteurization to obtain the product. In the preparation process of the fresh and wet sweet potato vermicelli, potassium cinnamate, thymol and aloe extract are added as fresh-keeping preservatives. The method overcomes the problem that chemical preservatives such as sodium dehydroacetate cannot be added into the fresh and wet sweet potato vermicelli, and prolongs the shelf life of the fresh and wet sweet potato vermicelli.

The invention belongs to the technical field of forest chemical industry and natural perfume extraction and separation, and particularly discloses a superheated steam distillation separation and recovery method for perfume components in cinnamon oil rectifying still residues. The method comprises the following steps: processing the cinnamon oil rectifying still residues by adopting a steam distillation method taking normal-pressure superheated steam as a desorption medium, carrying out condensation cooling and phase separation on distilled oil-water mixed gas, and collecting oily liquid or crystalline solid containing cinnamon spice components, and carrying out one or more physical isolation methods such as freezing crystallization, vacuum fractionation or rectification, recrystallization and the like to obtain natural cinnamon monomer spices such as o-methoxycinnamaldehyde, o-methoxycinnamic acid, phenethyl alcohol and the like. The method has the advantages of low equipment investment, simple and feasible operation, low production cost, clean and pollution-free process, good operation safety, high industrial application feasibility and the like.

The invention relates to the technical field of power cables, and provides a high-toughness corrosion-resistant power cable which comprises a conductor, and an insulating layer, an armor layer and a sheath layer are sequentially arranged on the outer side of the conductor. The sheath layer comprises the following raw materials in parts by weight: 35-45 parts of polyethylene, 35-45 parts of methyl vinyl silicone rubber, 35-48 parts of nitrile rubber, 6-8 parts of a plasticizer, 20-30 parts of filler, 1-2 parts of an antioxidant, 1-2 parts of a vulcanizing agent and 10-13 parts of a functional aid; the functional additive is prepared from the following raw materials: zinc oxide, cinnamic acid and cyclohexenecarboxylic acid. According to the technical scheme, the problem of poor toughness of the sheath layer of the corrosion-resistant power cable in the prior art is solved.

The invention provides a composite catalyst and a preparation method thereof, and a synthesis method of a p-methoxy cinnamate compound. The composite catalyst comprises a carrier modified by a modifier, and a metal salt and a choline substance loaded on the carrier. In the presence of the composite catalyst provided by the invention, a Claison-Schmidt condensation reaction of an aromatic aldehyde compound and an acetate compound is catalyzed to obtain the p-methoxycinnamate. The composite catalyst provided by the invention has the advantages of high reaction activity and selectivity, stable catalyst structure, difficult loss of active components, realization of cyclic application of the catalyst, no need of frequent replacement of the catalyst, simple operation, facilitation of continuous industrial production, substantial increase of the equipment utilization rate, and realization of industrial production. By using the composite catalyst provided by the invention, the p-methoxy cinnamate compound can be prepared under relatively mild reaction conditions, and the composite catalyst has no corrosion to equipment, does not generate waste water and waste salt, and is green and environment-friendly.

The invention relates to a polishing pad for polishing a silicon carbide wafer as well as a preparation method and application of the polishing pad. The polishing pad is prepared from the following raw materials in parts by weight: 10 to 15 parts of silicone oil, 25 to 35 parts of polyurethane prepolymer, 1 to 3 parts of anionic chain extender, 0.001 to 0.004 part of first catalyst and 2 to 5 parts of modified organic silicon microspheres. The chitosan quaternary ammonium salt and the cinnamic acid are adopted to modify the epoxy group organic silicon elastomer powder, and the modified organic silicon microspheres with high rigidity and high interface bonding force are prepared, so that the wear resistance and the storage modulus of the polishing pad are remarkably improved, and the requirement for high-precision polishing of silicon carbide wafers is met.

The invention belongs to the technical field of industrial silane preparation, and provides a natural silane rotor and a preparation method and application thereof.The preparation method comprises the steps that a pyridoxal phosphate solution and a 4-amino ethyl cinnamate solution are mixed and then react to obtain pyridoxal phosphate cinnamyl ester; and mixing the pyridoxal phosphate cinnamyl ester solution and the amino silane solution, and reacting to obtain the natural silane rotor. The silane rotor has a good conjugated structure, is stable in chemical structure, can be stored for a long time, is good in light stability, and is not liable to cause a photobleaching phenomenon. Besides, conjugated single and double bonds capable of freely rotating exist in the molecular structure, a typical flexible intramolecular rotation characteristic is presented, the conjugated structure can freely rotate in a dilute solution, a surface sightseeing signal is weak, the free rotation phenomenon is limited in a thick solution, the surface sightseeing signal is strong, and the surface sightseeing signal is strong. Therefore, the device can be used as a molecular tool for monitoring the change of the thin consistency of the silane, and can provide real-time, lossless and visual detection support for the development of a silane modulation process.

The invention discloses a preparation method of ethyl 4-chloroacetoacetate, and belongs to the technical field of compound synthesis. The method comprises the following steps: by taking diketene as a raw material, adding a polymethylsilsesquioxane polymerization inhibitor into a dichloromethane solvent, introducing chlorine at low temperature, carrying out chlorination reaction to generate 4-chloroacetoacetic acid, then esterifying the 4-chloroacetoacetic acid with absolute ethyl alcohol to obtain a crude product, and finally distilling and purifying to obtain the product. The preparation method is characterized in that a polymethylsilsesquioxane polymerization inhibitor is added before chlorination reaction, the polymerization inhibitor is prepared by grafting a functional monomer containing a 3, 5-di-tert-butyl-4-hydroxycinnamic acid structure onto surface-ethenylated polymethylsilsesquioxane microspheres, and the polymethylsilsesquioxane polymerization inhibitor has both steric hindrance and free radical capture capability. The method can effectively inhibit the self-polymerization and copolymerization tendency of diketene, intermediates and products in a reaction system, obviously reduces the generation of by-products such as dichloro and polychloro, enables the product to be high in yield and good in purity, and meets the quality requirements of high-end medical intermediates.

The present invention relates to the technical field of inks, and discloses a degradable water-based ink and a preparation method thereof. In the present invention, a DCPD petroleum resin reacts with 4-mercaptohydrocinnamic acid through a thiol-ene addition reaction to obtain a modified petroleum-based resin. Using diallylamine, mercaptopropyltriethoxysilane, 1,6-dibromohexane, epichlorohydrin, etc. as raw materials, through a thiol-ene addition reaction, a substitution reaction, and a quaternization reaction in sequence, a polysilane epoxy-based gemini quaternary ammonium salt is obtained. The epoxy group in the polysilane epoxy-based gemini quaternary ammonium salt undergoes a ring-opening reaction with the hydroxyl group in polyvinyl alcohol to obtain modified polyvinyl alcohol. Finally, the modified petroleum-based resin, modified polyvinyl alcohol, polylactic acid, defoamer, dispersant, etc. are stirred and mixed evenly to obtain a degradable water-based ink. The degradable water-based ink prepared in the present invention is experimentally proven to have good antibacterial properties and adhesion.

The present relates to compounds of formula (I) as defined herein. The compounds are suitable for protection against ultraviolet (UV) radiation. Further, the present invention is concerned with compositions comprising at least one compound of formula (I) and uses of said compounds as UV filters and light stabilizing agents.

The invention relates to a silica gel material and a preparation method thereof, and belongs to the technical field of high polymer materials. The silica gel material comprises the following components in parts by weight: 80-120 parts of vinyl silica gel, 10-25 parts of vinyl silicone oil, 15-25 parts of reinforcing filler, 3-6 parts of a modified antibacterial agent, 1-3 parts of a modified flexibilizer, 2-6 parts of a foaming agent and 2-6 parts of a cross-linking agent, a quaternary ammonium salt pre-product in the modified antibacterial agent permeates bacterial cell walls, reacts with proteins of cell membranes and adsorbs bacteria through electrostatic interaction, carbazole is combined with anions on the surfaces of the bacteria to destroy bacterial proteins, and cinnamic acid inhibits protein synthesis; a maleimide group in the modified toughening agent enhances the flexibility of a molecular chain, improves the toughness of the material, also improves the glass transition temperature and the melting point of the material, and prevents the material from embrittlement in a high-temperature environment, and polyurethane enhances the toughness of the material; the silica gel material prepared by the invention not only has a good antibacterial effect, but also has excellent heat resistance and toughening performance.

The invention relates to the technical field of traditional Chinese medicine detection, in particular to a characteristic spectrum construction method, a characteristic spectrum and a detection method of traditional Chinese medicine granules. The traditional Chinese medicine granules comprise protocatechuic aldehyde, hydroxysafflor yellow A, salvianolic acid B, cinnamic acid and cinnamaldehyde; the construction method comprises the following steps: taking protocatechuic aldehyde, hydroxysafflor yellow A, salvianolic acid B, cinnamic acid and cinnamaldehyde reference substances, and preparing a mixed reference substance solution; preparing a test solution from the traditional Chinese medicine granules; and respectively carrying out liquid chromatographic analysis on the mixed reference substance solution and the test solution to obtain the characteristic chromatogram of the traditional Chinese medicine granules. Wherein the liquid chromatographic analysis conditions comprise that a phosphoric acid solution is used as a mobile phase A, acetonitrile is used as a mobile phase B, and gradient elution is carried out. The problem that the quality of traditional Chinese medicine particles is difficult to control is solved.

The invention discloses a thin-layer chromatography identification method for cinnamon and ginger in vitality-preserving granules, and belongs to the technical field of pharmaceutical analysis. Aiming at the problems of step-by-step detection, serious cinnamic acid tailing and dependence on toxic solvents in the existing method, the method comprises the following steps: dissolving vitality-preserving particles in water, carrying out ultrasonic treatment, extracting filtrate by using absolute ether, merging extract liquor, evaporating to dryness, and dissolving by adding ethyl acetate to obtain a test solution; preparing a cinnamon reference medicinal material solution and a cinnamic acid and 6-gingerol reference substance solution; a silica gel GF254 thin-layer plate is adopted, petroleum ether-normal hexane-ethyl formate-formic acid is used as a developing solvent for developing, and inspection is conducted under the ultraviolet light of 254 nm and the ultraviolet light of 365 nm respectively. Cinnamon and ginger can be synchronously identified, spots are clear and free of trailing, no toxic solvent exists, durability is high, cost is low, and an accurate and reliable basis can be provided for quality control of the vitality-preserving granules.

The present invention provides A ceramide compound, comprising: a structure of general formula I or an enantiomer or diastereomer of general formula I:in which:R1 is selected from the condensation residues of ferulic acid, sinapic acid, abscisic acid, sotretinoin, tretinoin, fusidic acid, royal jelly acid, sorbic acid, caffeic acid or trans-cinnamic acid;R2 is selected from one of the following structures:—C15H29, —C15H31, —C15H27, —CHOHC14H27, —CHOHC14H29.The present disclosure also provides a ceramide compound containing conjugated carboxylic acid, preparation method therefor and application thereof. The invention reacts functional carboxylic acid with sphingosine base to obtain a class of ceramide compound with novel structure. The introduction of physiologically active molecular fragments of functional carboxylic acids into ceramides will enhance the original efficacy of this type of molecules and also improve the physical and chemical properties of ceramide compound. For example, improving the antioxidant properties of ceramide compound.

The invention relates to a pharmaceutical composition, the pharmaceutical composition contains an effective amount of active ingredients and pharmaceutically acceptable auxiliary materials, and the active ingredients comprise mangiferin, glycyrrhizic acid and cinnamic acid. The invention also relates to an application of the pharmaceutical composition in preparation of a medicine for treating or improving diseases, wherein the diseases are rheumatoid arthritis; the pharmaceutical composition contains an effective amount of active ingredients, and the active ingredients comprise mangiferin, glycyrrhizic acid and cinnamic acid. The pharmaceutical composition disclosed by the invention can be used for remarkably improving the severity of rheumatoid arthritis of a rat suffering from adjuvant-induced rheumatoid arthritis. And almost no adverse reaction or side effect exists.

The invention discloses a sugar derivative of hydroxycinnamic acid as well as a preparation method and application thereof in cosmetics. Specifically, the invention provides a sugar derivative of hydroxycinnamic acid. The compound is shown as a formula I in the specification. Compared with original hydroxycinnamic acid, the sugar derivative of hydroxycinnamic acid has better water solubility and stability, and has one or more effects of oxidation resistance, whitening, soothing, moisturizing, ultraviolet absorption and the like; when the composition is applied to cosmetics, light aging damage of skin can be relieved, and skin color can be brightened; .

The application discloses application of 2-amino isophthalic acid (2-AIA) as a MALDI matrix in characterization of oligosaccharide additives in food. The skeleton structure of 2-AIA has a strong ultraviolet absorption group and a protonation site, which is beneficial to laser energy transmission and desorption ionization process of the measured object. Meanwhile, 2-AIA has multiple polar functional groups, which can effectively enhance the directional combination of the hydroxyl group of 2-AIA and oligosaccharide, and improve the anti-interference ability of impurities in a complex system. In addition, 2-AIA and a traditional organic matrix alpha-cyano-4-hydroxycinnamic acid (CHCA) are combined as a binary matrix (CHCA / 2-AIA), which can play a synergistic role of the double matrix, significantly improve the detection sensitivity of oligosaccharide. On the other hand, the combination of CHCA and 2-AIA with different pH values can significantly improve the uniformity of the co-crystallization, and improve the accuracy and reproducibility of quantitative detection.

To provide a sebum secretion-inhibiting composition containing, as an effective ingredient, 3, 4, 5-trimethoxycinnamate thymol ester, or a stereoisomer, pharmaceutically acceptable salt, hydrate or solvate thereof.SOLUTION: The disclosed compositions can inhibit sebum secretion of skin or scalp exerting useful effects such as prevention or amelioration of seborrheic dermatitis, seborrheic scalp inflammation, prevention or amelioration of acne, or pore-shrinking.SELECTED DRAWING: Figure 1

The invention discloses an indole styryl oxadiazole bridging compound with toxoplasma gondii resisting activity, which is formed by bridging three pharmacophores of 3-indoleacetonitrile, oxadiazole and cinnamic acid. The invention relates to the technical field of antiparasite, and has the beneficial effects that the compound provides a new chemical entity for development of toxoplasma gondii resistant drugs, opens up a new direction for design of the antiparasite drugs, has a wide application prospect, and is suitable for industrial production. Particularly, the gene has an important transformation value in the aspects of immunodeficiency patient treatment and toxoplasma gondii prevention and control in the livestock breeding industry.

The invention belongs to the field of medicinal chemistry, and particularly relates to a peanut endogenous polypeptide Hypogin derivative and application thereof. The method comprises the following steps: firstly, carrying out structure simplification on a Hypogin endogenous peptide, searching an active fragment, and designing and synthesizing a series I of Hypogin derivatives; a Hypogin derivative with good activity in the series I is selected to be combined with cinnamic acid, and a series II compound is designed and synthesized. Research finds that the II-1 compound can well inhibit growth of sclerotium rolfsii mycelia, and also finds that I-12 affects a signal channel of sclerotium rolfsii PI3K, and potential targets are GPCR, RTK and PI3K of sclerotium rolfsii. Cytotoxicology tests show that II-1 has low human LO2 hepatotoxicity and conforms to the development direction of green bactericides. The Hypogin derivative disclosed by the invention has bacteriostatic activity, can be used as a basis for development of small peptide bacteriostatic agents, and has a good application prospect.

The invention belongs to the technical field of biological enzymes, and particularly relates to olefine acid reductase and application thereof in synthesis of indole-3-propionic acid. The invention relates to a clostridium sporogenes source cinnamic acid reductase, which is characterized in that the amino acid sequence of the clostridium sporogenes source cinnamic acid reductase is as shown in SEQ ID NO: 1. The clostridium sporogenes source cinnamate reductase is obtained by screening different enzyme sources, and compared with the previously reported acrylate reductase, the clostridium sporogenes source cinnamate reductase does not need the assistance of electron transfer protein, can reduce the energy load of an engineering bacterium host and promote the generation efficiency of a target product, and has a good industrial application prospect.

The invention relates to a process for the manufacturing of biobased 3-methyl-delta-valerolactone (3MdVL) and 3-methyl-1,5-pentanediol (3MPD) via one- pot hydrogenation of anhydromevalonolactone (aMVL) in the presence of a Raney- Nickel catalyst. The hydrogenation occurs without solvent at a temperature from 120ºC-180ºC, preferably at 130ºC-170ºC and a pressure between 15-30 bar, preferably at a pressure between 18 and 22 bar. The hydrogenation time may vary between 3 and 25 hours, preferably between 6 and 24 hours.

The invention discloses a corrosion-resistant polypropylene insulated cable and a preparation process thereof, and belongs to the technical field of cables. The corrosion-resistant polypropylene insulated cable sequentially comprises a cable core, a wrapping layer, an inner sheath layer, an armor layer and an outer sheath layer from inside to outside, the inner sheath layer and the outer sheath layer are both made of a corrosion-resistant polypropylene cable material; the corrosion-resistant polypropylene cable material is prepared from the following raw material components: polypropylene, POE (Polyolefin Elastomer), a plasticizer, a composite flame retardant, a heat-conducting filler, a lubricant, an ultraviolet light absorber and a nucleating agent, the composite flame retardant is prepared from the following raw materials: cyanuric chloride, 4-hydroxymethyl-1-oxo-1-phospha-2, 6, 7-trioxabicyclo [2.2. 2] octane, hydroxyl N-alkoxy hindered amine, ethidene diamine and N-(2-aminoethyl) maleimide; the heat-conducting filler is prepared from the following raw materials: graphene oxide, a silane coupling agent, boron nitride and 3, 5-di-tert-butyl-4-hydroxycinnamic acid; the corrosion-resistant polypropylene insulated cable prepared by the invention is relatively good in corrosion resistance, heat dissipation performance, flame retardance, thermo-oxidative aging resistance and mechanical property.

To provide a rubber composition to be a raw material of a vulcanized rubber excellent in steering stability and wet grip performance when used as a rubber part of a pneumatic tire, especially a pneumatic tire for motor sports.SOLUTION: A rubber composition comprising 100 parts by mass of a rubber ingredient containing at least a diene rubber, 0.1 to 10 parts by mass of a cinnamic acid compound having a hydroxyl or methoxy group-substituted aromatic ring, and 40 to 140 parts by mass of carbon black having a nitrogen-adsorption specific surface area of 140 to 250m2 / g. The cinnamic acid compound is a naturally occurring compound and is preferably at least one of 3, 4-dihydroxycinnamic acid and 3, 4-dimethoxycinnamic acid.SELECTED DRAWING: None

The invention relates to the technical field of preparation of composite packing materials, and particularly discloses a carbon-based stone-plastic composite packing material based on industrial solid waste as well as a preparation method and application of the carbon-based stone-plastic composite packing material. Comprising the following steps: S1, preparing the following raw materials in parts by weight: 90-96 parts of polyvinyl chloride, 5-10 parts of functionalized core-shell particles, 8-10 parts of sulfhydrylated bamboo fibers, 0.8-1.2 parts of a lubricant, 1.5-3.5 parts of a heat stabilizer, 0.2-0.4 part of a photoinitiator and 10-12 parts of an organic solvent; s2, preparing a mixed material; functionalized core-shell particles and sulfhydrylated bamboo fibers are added, outer layers of the functionalized core-shell particles are prepared by modifying titanium dioxide structures through KH-560 and then chemically bonding the modified titanium dioxide structures with alpha-methylcinnamic acid, cores are pretreated coal gangue, and the pretreated coal gangue not only has high specific surface area and active hydroxyl, but also can be chemically bonded with the sulfhydrylated bamboo fibers, so that the specific surface area of the core-shell particles is increased, and the specific surface area of the core-shell particles is increased. Heavy metal ions in the composite packing material can be effectively adsorbed, and the mechanical property is improved.

The present invention belongs to the technical field of pathogen control, and particularly relates to a cinnamic acid oxime ester compound, a preparation method and an application thereof. The cinnamic acid oxime ester compound has a structural formula as shown in Formula I: The preparation method of the compound of the present invention is simple in operation and easy to obtain raw materials. The compound has broad-spectrum bactericidal activity, and particularly has obvious inhibitory effects on Botrytis cinerea of tomato, Valsa mali of apple tree and Gaeumannomyces graminis of wheat, and can be used as a bactericide for the prevention and control of the above plant diseases.

The invention relates to an aroma-carrying multifunctional paper-based material and application thereof, and the aroma-carrying multifunctional paper-based material is prepared by a method comprising the following steps: reacting a carboxylic acid aroma substance with a chlorination reagent to prepare an acyl chloride derivative; the carboxylic acid flavor substance is p-methoxycinnamic acid or a combination of cinnamic acid and p-methoxycinnamic acid; mixing the obtained acyl chloride derivative with plant pulp and a catalyst, and carrying out esterification reaction to obtain carboxylic acid flavor substance grafted plant pulp; and making paper by taking the obtained carboxylic acid aroma substance grafted plant pulp as a raw material to obtain the aroma-carrying paper-based material. Specific carboxylic acid flavor substances are firmly connected to a plant fiber skeleton in a covalent bonding manner, so that long-acting slow release of fragrance can be realized, and the problems of easiness in volatilization, short fragrance retention time and the like in a traditional physical adding manner are effectively solved; meanwhile, the physical characteristics and combustion characteristics of the paper-based material prepared from the chemically modified cellulose are also optimized and improved, so that an idea is provided for developing a novel functional paper-based material.

[Problem] To provide a matsutake primordium having a high methyl cinnamate content and a method capable of obtaining such a matsutake primordium having a high methyl cinnamate content at an artificially high yield. [Solution] Cells having the ability to form a primordium that have been isolated from matsutake fruiting bodies are cultured in a medium containing a protein degradation product and having a specific phenylalanine concentration.

The present invention discloses an ion regulator, a preparation method and an application thereof. The ion regulator is formed by hydrogen bonding carboxylic acid and protein; the carboxylic acid is one or more of acrylic acid, crotonic acid and cinnamic acid; the protein is one or more of whey protein, soy protein and collagen. The ion regulator of the present invention can bind to cations in water to prevent scaling and avoid oil pipe corrosion; the ion regulator of the present invention belongs to the carboxylic acid compound and can effectively regulate the formation of agglomerated particles, while the low-charge organic matter in the hydrogen-bonded protein macromolecules can chelate with divalent cations, thereby stabilizing the ions in the fluid, controlling its agglomeration process, and thus preventing scaling. At the same time, the ions are combined to form nanoparticles, so that the size of the agglomerated particles can be controlled, and the agglomerated particles can be used for plugging, turning high-valent ions into "waste".