The invention discloses a # imgabs 0 # responsive
solvent and application thereof in efficient extraction and circulation of active ingredients of
polygonatum sibiricum, the # imgabs 1 # responsive
solvent is composed of the following components in percentage by
mass: # imgabs 2 # responsive amphiphilic compound,
alkyl primary amine or secondary amine with the
carbon chain length of C12-C16, accounting for 8-25% of the total
mass of the
solvent, and a # imgabs 1 # responsive amphiphilic compound and a # imgabs 2 # responsive amphiphilic compound, accounting for 8-25% of the total
mass of the solvent. The cosolvent is an
ethanol water solution with the
volume concentration of 60%-90% and accounts for 5%-12% of the total mass of the solvent; the initial pH (Potential of
Hydrogen) of the
solvent system is 7.5 to 8.5; the
antioxidant is selected from one or a combination of L-
ascorbic acid and
propyl gallate and accounts for 0.2-0.8% of the total mass of the solvent; the pH value of the solvent is reduced to 6.0-7.2 after # imgabs 3 # is introduced, the polarity parameter logP value is reduced to be larger than or equal to 1.5, and the logP value reversibly recovers to 90% or above of the initial value after # imgabs 4 # is released. The invention further discloses a # imgabs5
response type solvent and application of the # imgabs5
response type solvent in efficient extraction and circulation of active ingredients of
polygonatum sibiricum, and efficient extraction of the active ingredients of
polygonatum sibiricum and reversible recycling of the solvent are achieved.