62 results about "Hexamidine" patented technology

Skin care compositions containing N-acyl amino acid, particularly N-acyl derivatives of Phenylalanine or Tyrosine, their isomers, or their salts; at least one other skin care active selected from sugar amines, vitamin B3, retinoids, peptides, dialkanoyl hydroxyproline, hexamidine, salicylic acid, and phytosterol; and a dermatologically acceptable carrier for the N-acyl amino acid and the skin care active. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the skin care composition of the invention.

The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

Method for regulating the condition of mammalian skin comprising the steps of applying a first personal care composition to an area of skin where regulation is desired, wherein the first personal care composition comprises at least one skin care active selected from the group consisting of niacinamide, salicylic acid, peptides, N-acetyl glucosamine, panthenol, butylated hydroxytoluene, N-acyl amino acid compounds, hexamidine, green tea, ascorbyl glucoside, hexanediol, pentanediol, a skin lightening agent, a heat shock protein potentiator, and mixtures thereof, and delivering energy to the area of skin by contacting the skin with an energy delivery device for a treatment period of at least 2½ minutes, wherein the energy delivery device comprises a skin-contacting surface that is controllably heatable to a temperature of from 37° C. to 50° C.

Personal care compositions containing at an alpha-glucan and / or beta-glucan; at least one additional skin and / or hair care active selected from the group consisting of sugar amine, vitamin B3, retinoids, peptides, phytosterol, dialkanoyl hydroxyproline, hexamidine, salicylic acid, n-acyl amino acid compounds, sunscreen actives, water soluble vitamins, oil soluble vitamins, hesperedin, mustard seed extract, glycyrrhizic acid, glycyrrhetinic acid, carnosine, Butylated Hydroxytoluene (BHT) and Butylated Hydroxyanisole (BHA), menthyl anthranilate, cetyl pyridinium chloride, ergothioneine, vanillin or its derivatives, diethylhexyl syrinylidene malonate, melanostatine, sterol esters, tetrahydrocurcumin, their derivatives, their precursors, and combinations thereof; and a dermatologically acceptable carrier.

Skin care compositions containing dehydroacetic acid, its isomers, salts, and derivatives thereof; at least two skin care actives selected from sugar amines, vitamin B3 compounds, phytosterols, salicylic acid compounds, hexamidines, dialkanoyl hydroxyproline compounds, flavonoids, n-acyl amino acid compounds, and their derivatives, and combinations thereof; and a dermatologically acceptable carrier for the dehydroacetic acid and the skin care actives. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the skin care composition of the invention.

A method of facilitating the cosmetic delivery of a hexamidine compound to keratinous tissue via a composition including the hexamidine compound, including the step of incorporating a thickening agent that is not negatively-charged into the composition.

The invention discloses a preparation method of acne-removal repair stoste containing katsumade galangal seed extract, and belongs to the field of facial care. The acne-removal repair stoste comprisesthe following raw materials in parts by weight: 0.1-4 parts of a katsumade galangal seed extracting solution, 1-10 parts of polyalcohol, 1-10 parts of a moisturizing agent, 0.1-1 part of a thickeningagent, 0.02-0.1 part of a chelating agent, 0.1-1 part of a pH value regulator, 0.5-10 parts of an acne-removal repairing agent, 0.3-8 parts of a skin conditioner, 0.1-1 part of a preservative and thebalance of deionized water. In the invention, by adding various plant herbal acne-removal essences such as the katsumade galangal seed extract, tingia olibanoresin extract, centella asiatica extract,dendrobium stem extract, wild soyabean protein, herba houttuyniae extract, hexamidine di(isethionic acid) salt and the like, the acne-removal repair katsumade galangal seed stoste has the effects ofeffectively inhibiting excessive secretion of sebum, opening blocked pores, killing acne bacilli, eliminating inflammation and repairing damaged skin, so that the skin is recovered to a healthy and natural smooth state; in addition, the acne-removal repair stoste is mild and non-irritating.

The invention provides a fresh and cool oil-control silicon oil-free hair shampoo which is composed of lauroyl collagen amino acid, sodium cocoamphoacetate, cocamidopropyl betaine, decyl glucoside, glyceryl laurate, peg-120 methyl glucose dioleate, stearamide propyl dimethyl ammonium, guar gum hydroxypropyl trimethyl ammonium chloride, polyquaternary ammonium salt-10, peg-7 glyceryl cocoate, hydroxyethylurea, capryloyl glycine, citric acid, allantoin, triethanolamine, hydrolysis avenin, hydrolyzed collagen, ginger root oil, palmitamidopropylamine trimethyl ammonium chloride, hexamidine di(ethylenhydrin-sulfonic acid) salt and a matrix. The invention further discloses a making method of the hair shampoo. The hair shampoo is capable of adjusting hair environments, enabling hair to be at a silicon oil free of small silicon oil deposition state, controlling oil, removing dandruff, making hair fresh and cool, nutrificating scalp and hair, repairing damaged hair, preventing hair dry yellow,hair spitting or hair breakage, and making the hair soft and glary.

Personal care composition including a first skin and / or hair care active cetyl pyridinium chloride; and at least one additional skin and / or hair care active selected from the group consisting of tetrahydrocurcumin, sugar amine, vitamin B3, retinoids, hydroquinone, peptides, phytosterol, dialkanoyl hydroxyproline, hexamidine, salicylic acid, n-acyl amino acid compounds, sunscreen actives, water soluble vitamins, oil soluble vitamins, hesperedin, mustard seed extract, glycyrrhizic acid, glycyrrhetinic acid, carnosine, Butylated Hydroxytoluene (BHT) and Butylated Hydroxyanisole (BHA), ergothioneine, vanillin or its derivatives, diethylhexyl syrinylidene malonate, melanostatine, sterol esters, idebenone, dehydroacetic acid, Licohalcone A, creatine, creatinine, feverfew extract, yeast extract, beta glucans, alpha glucans, their salts, their derivatives, their precursors, and / or combinations thereof; and a dermatologically acceptable carrier. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the personal care composition of the invention.

The invention relates to acne removing cream and a method for preparing the same. The acne removing cream comprises, by weight, steareth-2, lauroyl glutamate, steareth-21, cetyl alcohol, glyceryl stearate, dimethicone, isomerization cetane, capric triglyceride, isopalmitic acid ethylhexyl acrylate, vitamin E, bisabolol, propylene glycol, dipotassium glycyrrhizinate, butanediol, hexamidine (hydroxyethanesulphonic acid) dibasic, EDTA (ethylene diamine tetraacetic acid)-disodium, water, matrine, preservatives, asiaticoside, pH (potential of hydrogen) regulators and thickeners. The acne removing cream and the method have the advantages that various raw materials are mixed with one another, and accordingly facial skin cleaning and care effects can be realized; pimple, acne, papule, pustule and the like on the faces of users can be effectively removed.

The invention discloses a sulfate-anionic-surfactant-free silicone-oil-free shampoo composition. The shampoo composition is composed of 10-45% of anionic surfactant, 8-20% of zwitterionic surfactant, 5-15% of nonionic surfactant, 0.1-3% of conditioner, 0.1-3% of plant extract, 0-1% of preservative, 0.1-1.0% of essence and the balance of deionized water. The shampoo composition comprises one or two of disodium lauryl sulfosuccinate, sodium cocoyl glutamate and sodium lauroyl sarcosine as the main surfactant which is compounded with cocoyl hydroxyl sulfobetaine, lauryl alkyl glycoside and isostearamide monoisopropanolamine. A polyquaternary ammonium salt-10 and a polyquaternary ammonium salt-7 are used as the conditioner; keratin, panthenol and shea butter grease adhesive are matched with the plant extract nutrient; and hexamidine (hydroxy-ethyl sulfonic acid) salt is used as one of the anti-dandruff bactericides. The shampoo composition is free of sulfates and silicone oil, and is capable of well cleaning and conditioning the hair and scalp.

Compositions useful for regulating the condition of mammalian keratinous tissue needing such treatments are provided. An exemplary composition comprises a safe and effective amount of glycyrrhizic acid and / or glycyrrhetinic acid; a safe and effective amount of an active selected from the group consisting of N-acyl amino acid compounds, hexamidine, cetyl pyridinium chloride, ergothioneine, and combinations thereof, and a dermatologically acceptable carrier.

The invention discloses a highly nutritious hair conditioner. The hair conditioner comprises purified water, glyceryl stearate, propanediol, polydimethylsiloxane, Hedera Helix, lanolin, vitamin E, D-panthenol, lavender oil, chitosan, propolis, ginseng, diazolidinyl urea, butylated hydroxytoluene, a Carbomer resin, allantoin and a hexamidine disalt. The highly nutritious hair conditioner of the invention, which adopts various nutrition and conditioning components, prevents hair from the disoperation by extraneous unfavorable factors, repairs damaged hair, and makes healthy and natural hair be rapidly recovered.

The invention provides a bacteriostatic and mite-removing shampoo and a preparation method thereof, and relates to the field of daily chemicals. The bacteriostatic and mite-removing shampoo is prepared from the following raw materials: sodium laureth sulfate, decyl glucoside, behenamidopropyl dimethylamine, cocamide MEA, Polyquaternium-52, Cocamidopropyl betaine, ziziphus joazeiro bark extract, Piroctone ethanolamine salt, Gentian extract, guar hydroxypropyl trimethyl base ammonium chloride, polyquaternary ammonium salt-10, Cnidium Monnieri fruit extract, dimethiconol, amino-terminated Polydimethylsiloxane, plant extract, nicotinamide, etidronic acid, Carbomer, sodium hydroxide, preservatives, flavors, hexamidine bis (hydroxyethanesulphonic acid) salt, menthol and water, wherein the plantextracts are clove bud extract, litsea eubeba extract, thyme extract and lightyellow sophora root extract. The shampoo obtained through the mutual matching of the components and the optimization of the preparation method has good antibacterial and mite-removing effects.

The invention discloses fresh skin acne-mite cream, wherein the fresh skin acne-mite cream is composed of water, ethanol, vitamin B6, vitamin B, vitamin E, allantoin, abietic acid, vitamin C, hexamidine dihydrochloride, sodium hyaluronate, tea-seed oil, egg oil, glycyrrhiza flavonoids, honeysuckle flower extract, ginseng extract, seabuckthorn fruit oil, phellodendron bark extract and aloe extract. The fresh skin acne-mite cream is used for treating acne caused by such reasons as mite and capable of inhibiting sebum overflow of oily skin, alleviating adverse reactions and reducing the formation of pigment impressions; the fresh skin acne-mite cream has the functions of whitening, resisting against wrinkle, slowing the ageing process and brightening the skin and can be also used for performing treatment, moisturization and care on normal skin and reducing the formation of age pigment.

The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. Said methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions.

The invention discloses an amino acid antibacterial agent synergism hexamidine antibiotic composition. The amino acid antibacterial agent synergism hexamidine antibiotic composition comprises one or more of an amino acid pattern antibacterial agent and hexamidine or derivatives. The invention further relates to a preparation method of the composition, and an application of the composition for sterilizing and bacteriostasis of removing dandruff, removing acnes, sterilizing, preventing putrefaction and the like. The antibiotic composition is green, safe and efficient, under the condition of sameantibacterial efficacy, the using amount of the hexamidine and the derivatives thereof can be reduced, the cost is reduced, the irritating and environmental pollution are reduced, and the antibioticcomposition can be used for washing type and remaining type daily chemicals.

The invention discloses cationic bactericidal gel. Each 100 parts of the cationic bactericidal gel is prepared from the following raw materials in parts by weight: 0.05-0.5 part of hexamidine dihydroxyethyl sulfonate, 0.02-0.2 part of benzalkonium chloride, 0.03-0.3 part of cetylpyridinium chloride, 0.5-2 parts of carbomer U20, 0.3-1.5 parts of carbomer U21, 5-10 parts of propylene glycol, 0.5-2 parts of aminomethyl propanol and the balance of water. The invention further discloses a preparation method of the cationic bactericidal gel and a bacteriostatic aloe gel product containing the same. The problem that in the conventional technology, after an anionic carbomer and an anionic bactericide are mixed, a flocculent precipitate is produced is solved; the obtained bacteriostatic aloe gel product not only has the efficacies of activating cell vitality, delaying skin aging, eliminating inflammation, astringing and conditioning skin and the like, but also has good antibacterial and bacteriostatic effects; in addition, after the bacteriostatic aloe gel product is used, the skin feels fresh, cool and non-sticking; and the bacteriostatic aloe gel product is safe and free of side effects.

A deodorant stick having a substituted or unsubstituted 2-pyridinol-N-oxide material and at least one material selected from the group consisting of hexamidine, magnesium carbonate, zinc carbonate, thymol, magnesium hydroxide, dead sea salt, calcium carbonate, polyvinyl formate, salycilic acid, niacinamide, and combinations thereof.

The invention discloses a method for measuring hexamidine, chlorhexidine, and salts thereof in cosmetics. The method comprises the following steps: (1) preprocessing a cosmetic sample; (2) detecting the hexamidine, chlorhexidine, and salts thereof in the cosmetic sample through HPLC (high performance liquid chromatography); (3) drawing a standard curve, and calculating; (4) carrying out confirmatory tests by a LC(liquid chromatography)-MC(mass chromatography) / MC method. The provided method uses HPLC to synchronously measure hexamidine, chlorhexidine, and salts thereof in cosmetics, and is simple, convenient, rapid, and accurate. The detection limit, quantification limit, recovery rate, and precision of the method are all qualified.

The invention discloses herbal plant extraction acne removing essence. The herbal plant extraction acne removing essence includes water, butanediol, glycerol, propylene glycol, glycolic acid, PEG-60 hydrogenated castor oil, ethyl hexyl glycerin, glycerol caprylate, lactobacillus / pear juice fermentation product filtrate, O-cymene-5-alcohol, a phellodendron bark extract, a white willow leaf extract,a Chinese rehmannia root extract, an Indian neem leaf extract, a scutellaria root extract, a wild soybean seed extract, a north American witch hazel extract, a calendula extract, a hexamidine dihydrochloride (hydroxyethyl sulfonic acid) salt, an antiseptic and a coloring agent. According to the herbal plant extraction acne removing essence, the herbal plant extraction acne removing essence is prepared from the components: a plant extraction component and a matched incidental component, skin water and oil balance can be effectively regulated, acne is removed and acne marks are diluted, damagedskin is repaired, and the acne removing essence is natural, mild, good in safety, effective in acne removing effect, simple in preparation process, controllable, low in cost, and suitable for extensive promotion.

The invention discloses a dandruff-removing and hair-washing composition with quick acting. Calculated by weight percent, a formula of the dandruff-removing and hair-washing composition comprises the following components: 5.0 to 50.0 percent of surfactant, 0.1 to 5.0 percent of antidandruff agent, 0.01 to 6.0 percent of salicylic acid or derivative thereof and the balance of water-containing carrier, wherein the antidandruff agent is a mixture of dichlorophenyl imidazole dioxolane and a hexamidine derivative. The invention utilizes the dichlorophenyl imidazole dioxolane to combine with the hexamidine derivative so as to form a complementary antimicrobial spectrum; and the salicylic acid or the derivative thereof attached to the scalp can slowly release the trace salicylic acid under the inherent subacid condition of the scalp, and the trace salicylic acid can generate a mild keratose stripping effect, thereby promoting the quick falling of keratinized scalp cells and creating a condition for the more sufficient contact of the antidandruff agent and microorganisms in the corneum so as to suppress and kill microorganisms (a malassezia yeast) which exists on the scalp and causes dandruffs effectively and finally achieve the aim of controlling the dandruffs.

Compositions useful for regulating the condition of mammalian keratinous tissue needing such treatments are provided. An exemplary composition comprises a safe and effective amount of glycyrrhizic acid and / or glycyrrhetinic acid; a safe and effective amount of an active selected from the group consisting of N-acyl amino acid compounds, hexamidine, cetyl pyridinium chloride, ergothioneine, and combinations thereof; and a dermatologically acceptable carrier.

The present invention relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of a skin care composition comprising:a) a safe and effective amount of a hexamidine compound selected from the group consisting of hexamidine, its salts, and derivatives;b) a safe and effective amount of one or more skin care active selected from the group consisting of sugar amine, vitamin B3, retinoid, peptide, phytosterol, butylated hydroxytoluene and butylated hydroxyanisole, their derivatives, and combinations thereof; andc) a dermatologically acceptable carrier for the hexamidine and the skin care active.In additional embodiments, the above composition is suitable for preventing, retarding, and / or treating dark under-eye circles, puffy eyes, sagging, sallowness as well as spider vessels and / or red blotchiness of skin, promoting skin desquamation, exfoliation, and / or turnover, regulating and / or reducing pore size appearance, preventing / retarding tanning, regulating oily / shiny appearance, preventing, retarding, and / or treating hyperpigmentation in mammalian skin, preventing, retarding, and / or treating itchiness of mammalian skin, preventing, retarding, and / or treating dryness of skin, preventing, retarding, and / or treating fine lines and wrinkles, preventing, retarding, and / or treating skin atrophy of mammalian skin, softening and / or smoothing lips, hair and nails of a mammal, and preventing, retarding, and / or treating the appearance of cellulite in mammalian skin.

Disclosed is herein a composition comprising hexamidines, derivatives thereof, or pharmaceutically acceptable salts thereof; and retinoids, derivatives thereof, or pharmaceutically acceptable salts thereof, as an active ingredient. The composition of the present invention has effects for preventing, improving or treating acne; controlling sebum; pore-controlling; and preventing, improving or treating skin pigmentation. Also, the composition of the present invention could alleviate skin-irritations caused with retinoids by including ceramides.

The invention belongs to the field of cosmetics, and particularly relates to acne removal cream and a preparation method thereof. Cymene-5-alcohol and hexamidine or hexamidine bis(isethionic acid) salts in the acne removal cream are major ingredients for sterilization, inflammation diminishing and acne removal; tagemete and paeonol can be matched for enhancing the acne removal effect; paeonol canpromote the blood circulation of the face skin, can activate the senile surface cells, enables the skin to be white and tender, achieves the anti-aging effect, and particularly has a good effect on whelks; tagemete achieves an obvious allergy inhibition effect through H2 acceptor retardation; the itching symptom can be effectively relieved; a proper proportion of other raw materials such as anti-allergic agents, thickening agents, emulsifying agents, water-retention agents, skin conditioning agents, emollients, penetrants, analgesics, antiallergic agents, preservatives and perfuming agents arematched; the finally prepared acne removal cream has the advantages that the recipe is reasonable; the use is convenient; the acne removal effect is good; the healing restoration is fast; during theacne removal, the effect of promoting the skin wound restoration can be achieved at the same time.

A moistening moisture-retaining anti-inflammation anti-acne camellia seed facial cleanser comprises, by mass part, 30-50 parts of a camellia seed extracted liquid, 15-25 parts of sodium lauryl glutamate, 5-10 parts of cocamidopropyl betaine, 3-6 parts of sodium cocoamphoacetate, 5-10 parts of sodium cocoyl glycinate, 2-5 parts of alkyl glycoside, 0.5-1 part of PEG-120 methyl glucose trioleate, 0.05-0.1 part of disodium ethylene diamine tetraacetate, 4-10 parts of glycerin, 0.5-1 part of water-soluble jojoba oil, 5-10 parts of camellia oil, 0.5-2 parts of polyquaternary ammonium salt-7, 0.05-0.1 part of hexamidine di(hydroxyethanesulphonic acid) salt, 0.1-0.3 part of essence, 0.1-0.3 part of a rhizoma chuanxiong extract, and 10-40 parts of pure water. The camellia seed facial cleanser desensitizes the camellia seed extracted liquid. Through cooperation with a mild cleanser and natural camellia japonica seed oil, the facial cleanser has the face-cleaning, skin-moistening, moisture-retaining, anti-inflammation and anti-acne effect.