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6 results about "Hexamidine" patented technology

Hexamidine is an antiseptic and disinfectant. Hexomedine is the trade name of a diisethionate solution (1/1.000) of hexamidine. Hexamidine is used primarily as its diisethionate salt, which is more water-soluble than the dihydrochloride. The dihydrochloride was first synthesized and patented as a trypanocide for May & Baker in 1939. Its amoebicidal properties emerged in the 1990s. The exact mechanism of its biocidal action is unknown, but presumed similar to quaternary ammonium compounds, involving binding to the negatively charged lipid membranes of pathogens. Hexamidine and its shorter congener, propamidine, are used as antiseptics and preservatives in pharmaceuticals and cosmetics. They are particularly used for the topical treatment of acanthamoebiasis (Acanthamoeba keratitis).

Synthesis process of hexamidine dihydroxyethyl sulfonate

The invention belongs to the technical field of organic synthesis, and particularly relates to a novel synthesis process of hexamidine dihydroxyethyl sulfonic acid. The synthesis method comprises the following steps: (1) adsorbing ammonia gas by using the MOFs material; (2) carrying out condensation reaction to prepare an SN1 intermediate; (3) carrying out addition reaction to prepare an SN2 intermediate; and (4) sulfonating and salifying to prepare a final product. The synthesis process provided by the invention is simple to operate, high in safety and less in three wastes, the catalyst can be recycled, the yield of the prepared hexamidine dihydroxyethyl sulfonic acid is greatly improved, the total yield of the product can reach 90% or above, and the purity reaches 99.0% or above.
Owner:QINGDAO SANRENXING CHEM CO LTD

Herbal plant extraction moisturizing essence gel conditioning and soothing formula and production process thereof

The invention discloses a herbal plant extraction moisturizing essence gel conditioning and soothing formula and a production process thereof, and relates to the technical field of cosmetics. According to the formula, water, glycerin and butanediol are used for constructing a triple moisturizing substrate, plant extraction conditioning components such as euglena parvata polysaccharide and myrothamnus flabellifolia extract are compounded, the honeysuckle flower extract and hexamidine bis (isethionate) salt are matched to achieve the mild antibacterial and anti-inflammatory effects, and all the components are combined according to the precise mass percent; according to the production process, the stability of the formula is guaranteed through the temperature control process of high-temperature dissolution, constant-temperature stirring and gradient cooling. The gel can achieve long-acting water locking for 48 hours, effectively inhibit breeding of harmful bacteria such as staphylococcus aureus and escherichia coli, relieve skin slight inflammation, moisten and nourish superficial layer meridians and collaterals of the skin surface and relieve limb acid precipitation caused by sedentariness or dryness, can improve the skin barrier toughness by 25% after being continuously used for 14 days, is clear and moist in texture and free of sticky feeling, does not need to build tolerance, and is free of side effects. The massager is suitable for multiple scenes such as light massage of sedentary people and is suitable for wide people.
Owner:GUANGZHOU YAJIA INNOVATION TECHNOLOGY CO LTD

Hair care composition containing humulus lupulus extract as well as preparation method and application of hair care composition

The invention relates to a hair care composition containing a humulus lupulus extract and a preparation method thereof.The hair care composition containing the humulus lupulus extract is prepared from the humulus lupulus extract, a radix scutellariae extract, caffeine, a chamomile extract, nicotinamide, dipotassium glycyrrhizinate, hexamidine bis (isethionic acid) salt, cyclodextrin, a skin conditioner, polyhydric alcohol and deionized water; by scientifically compounding the humulus lupulus extract, the radix scutellariae extract and caffeine and cooperating with other components in the system, the obtained hair care composition is low in irritation, capable of adjusting scalp grease secretion, capable of achieving an obvious oil control effect, capable of effectively reducing scalp water loss, capable of improving the scalp microenvironment, capable of effectively protecting scalp and resistant to static electricity.
Owner:OPAL COSMETICS HUIZHOU

Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl) butan-2-one, and cosmetic composition containing same

ActiveUS12521329B2BiocideCosmetic preparationsBiotechnologyPiroctone olamine
The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an additional compound chosen from a monovalent or divalent metal salt of pyrithione, piroctone olamine, diazolidinylurea, a hexamidine compound, and imidazolidinylurea,and also to a cosmetic composition containing such a mixture.Application to caring for, making up and cleansing keratin materials.
Owner:LOREAL SA

Composition comprising totarol and hexamidine or derivative or pharmaceutically acceptable salt thereof, and uses of composition

The present invention relates to a composition comprising: totarol; and hexamidine or a derivative or a pharmaceutically acceptable salt thereof, and to uses of the composition, wherein the composition may have an antimicrobial effect, an inflammation-inhibiting effect, and a dandruff-alleviating effect.
Owner:COSMAX INC

Aquaporin 3 (AQP3) mRNA expression promoter

To provide a aquaporin 3 (AQP3) mRNA expression promoter excellent in action effect.SOLUTION: The aquaporin 3 (AQP3) mRNA expression promoter contains nicotinamide as an active ingredient (except a promoter containing a combination of nicotinamide, hexamidine and pentanediol as active ingredients).SELECTED DRAWING: None
Owner:MARUZEN PHARMA