The invention discloses the hot processing technology of a cake with stuffing. The cake with the stuffing comprises, by weight, 30%-32% of fresh egg, 18%-25% of white granulated sugar, 22%-24% of wheat flour, 0.8%-1.2% of starch, 5.4%-6.5% of oil, 5%-6% malt syrup, 0.45%-0.58% of strawberry powder, 2.2%-3.93% of sorbitol, 1.2%-1.4% of Tianjin Riken foaming agent, 1.5%-1.91% of glycerin, 0.01%-0.011% of citric acid, 0.08%-0.14% of xanthan gum, 0.3%-0.312% of edible salt, 1.0%-1.4% of inulin, 3.5%-3.9% of water, 0.035%-0.039% of potassium sorbate, 0.015%-0.019% of sodium dehydroacetate, 0.002%-0.0023% of edible essence and 0.00075%-0.00078% of carmine. Before the cake is baked, the stuffing is injected into the cake, the stuffing and a cake body are put into a baking oven together for baking and sterilization, so that the technology is safer than the cool processing technology that the stuffing is injected into the cake body after the cake body is baked and flow line production is facilitated.