373 results about "Choline chloride" patented technology

The invention belongs to the technical field of medicines, and particularly relates to a composition for improving obesity and promoting cardiovascular health as well as a preparation method and application thereof. The composition is prepared from the following components in parts by weight: 5 to 20 parts of glycine betaine, 1 to 5.5 parts of choline chloride, 0.5 to 4 parts of L-theanine, 1 to 15 parts of alpha-ketoglutarate calcium, 0.5 to 3 parts of black ginger extract, 0.05 to 0.25 part of black pepper extract, 0.5 to 3 parts of ginkgo leaf extract and 1 to 6 parts of black garlic juice powder. According to the invention, the eight components are selected and are scientifically combined in an optimal quantity ratio range, and the prepared composition can better reduce the inflammation level of a body, regulate abnormal blood fat, improve the lipid metabolism disorder state and effectively reduce impulsive diet behaviors, so that comprehensive improvement of obesity and cardiovascular related risks is realized, and the health-care effect of a human body is improved. The body is effectively assisted to maintain metabolic health.

The application belongs to the technical field of deep eutectic solvents, and particularly relates to a ternary deep eutectic solvent and preparation and application thereof. The ternary deep eutectic solvent is composed of choline chloride, 5-sulfosalicylic acid and gamma valerolactone according to a molar ratio of 1:4:(3-25). The strong hydrogen bond network structure between the green solvent system first destroys the ester bond between lignin and hemicellulose, then cuts off the beta-O-4 bond between lignin molecules, so as to separate lignin. Meanwhile, the deep eutectic solvent can improve the stability of carbon cations due to the conjugation effect between the lone pair electrons on the heteroatom oxygen and the central carbon in the molecular structure of gamma valerolactone, so as to inhibit the condensation reaction of lignin.

The invention discloses a method for synthesizing eutectic gel by in-situ extraction of lignin, and belongs to the technical field of gel materials.The method comprises the steps that choline chloride and acrylic acid are mixed, heated in an oil bath and stirred, and a eutectic solvent is obtained; cooling the solvent, adding dried and crushed wood powder, heating in an oil bath, extracting to obtain a mixed solution, and centrifuging to obtain supernate; adding a cross-linking agent and an initiator into the supernate, heating, stirring, and cooling to room temperature to obtain a pre-polymerized solution; and pouring the pre-polymerized liquid into a polytetrafluoroethylene mold, and carrying out ultraviolet curing to obtain the target gel. According to the method, the natural structure and active groups of the lignin are reserved to the maximum extent, the method is low-carbon, energy-saving, green and sustainable, in-situ lignin and a polymerization network cooperate, the gel is endowed with higher mechanical strength, environmental stability and functional diversity, and the limitation of existing lignin doped gel is broken through.

The invention relates to the technical field of aquatic product preservation, and discloses a natural eutectic solvent for maintaining the quality of frozen penaeus vannamei boone and application, the natural eutectic solvent is composed of choline chloride, sorbitol and water, the molar ratio of choline chloride to sorbitol is (1-5): (1-5), and the mass of water is 15-25% of the total mass of choline chloride and sorbitol. The invention also provides an application of the solvent, and the application comprises the following steps: soaking the penaeus vannamei meat in the solvent, and then freezing and storing the penaeus vannamei meat. A supramolecular network system is constructed through hydrogen-bond interaction between choline chloride and sorbitol, growth of ice crystals in the freezing storage process is inhibited, a protein structure is stabilized, and loss of unfrozen juice is reduced, so that the quality of the penaeus vannamei, such as texture, color and flavor, is maintained. The natural deep-eutectic solvent is natural and safe in component, low in heat, simple to prepare and convenient to apply, the application limitation of a traditional anti-freezing agent is solved, and the natural deep-eutectic solvent has a good industrial prospect.

The invention relates to the field of plant growth regulators, in particular to a conditioner group for improving the grain quality and the rice quality of direct seeding rice and a preparation and use method thereof.The preparation method of a conditioner in the initial heading stage comprises the following steps that 1, 6-benayl aminopurine is dissolved in a diluted hydrochloric acid solution in a assisted mode, and a 6-benayl aminopurine solution is obtained; step 2, adding choline chloride into the solution obtained in the step 1, stirring to obtain a mixed solution, transferring the mixed solution into a volumetric flask, and adjusting the pH value; 3, abscisic acid powder is dissolved with absolute ethyl alcohol, volume metering is carried out after dissolution to form a stock solution, and then PH adjustment is carried out. Two conditioners are included and sprayed in the initial heading stage and the full heading stage respectively, glumous flower degeneration can be reduced, the photosynthetic production capacity of the upper three leaves after flowering can be improved, assimilation substances are promoted to be transferred to grains, especially the filling state of vulnerable grains is improved, and the yield of the seedlings is increased. Finally, the grain number, the maturing rate, the grain weight and the yield are improved, meanwhile, the head rice rate of rice can be improved, and the protein content is reduced, so that the palatability of rice is improved.

The invention provides a preparation method of a stable-size and high-strength laminated timber, which comprises the following steps of: mixing boric acid and choline chloride, and heating and melting at 90 DEG C to form a uniform, stable and transparent liquid, so as to obtain a deep eutectic solvent DES; the preparation method comprises the following steps: under the vacuum degree of-0.1 MPa, dipping wood veneers in DES, performing high-temperature steam sterilization treatment under the condition of 121 DEG C, assembling the veneers subjected to multi-layer treatment according to a rift-grain mode, and performing hot pressing at 160 DEG C to obtain the laminated timber with stable size and high strength. The prepared laminated timber has dimensional stability and good mechanical properties, has structural applicability of direct contact with a moisture environment, and has the advantages of mildew resistance, corrosion resistance, flame retardance and the like.

The invention relates to the technical field of microbial fermentation, in particular to a fermentation medium for producing oxytetracycline. According to the fermentation culture medium, a corn starch-molasses-wheat hydrolyzed sugar composite carbon source, a soybean cake powder-corn steep liquor-yeast extract composite nitrogen source and a choline chloride-betaine-L-lysine precursor accelerant in a specific proportion are used as a core innovative system, and a form regulating agent, a defoaming agent and inorganic salt are cooperatively added. Through the synergistic effect of multiple components, the fermentation titer and yield of oxytetracycline are remarkably improved, the fermentation period is shortened, the generation of heteroacid is effectively inhibited, the mycelium form is optimized, and the oxytetracycline fermentation medium is suitable for industrial large-scale production of oxytetracycline.

The application discloses a method for selectively extracting metals from waste ternary lithium batteries by using a eutectic solvent. The method uses a eutectic solvent DES synthesized by choline chloride and oxalic acid as an extraction agent, quotes dimethyl sulfoxide DMSO and water as diluents, introduces a circulation and extraction step on the basis of metal element series immersion, i.e. extracts lithium oxalate from the leaching solution with ethanol and recycles the DES by fractional distillation, and makes innovations in recycling of metal lithium and recycling of the DES. The application has the advantages of high efficiency extraction, high precision purification, innovative extraction of lithium element and innovative recovery of the reagent DES.

The invention discloses a method for efficiently preparing high-activity hericium erinaceus polysaccharide from waste in the edible mushroom industry, and belongs to the technical field of deep processing of edible mushrooms and recycling of waste. The method comprises the following steps: carrying out steam explosion pretreatment on hericium erinaceus waste mushroom residues, and carrying out synergistic compatibility on the hericium erinaceus waste mushroom residues, tea residues, bean residues and citrus residues which are subjected to specific enzymolysis to prepare a liquid fermentation culture medium; a two-stage control strategy is adopted for submerged fermentation of hericium erinaceus liquid, and hypha proliferation and polysaccharide synthesis conditions are optimized; and after fermentation is finished, extracting and purifying mycelium polysaccharide by adopting a choline chloride-lactic acid eutectic solvent system. According to the method, high-valued utilization of the edible fungus chaff and various agricultural byproducts is achieved, the content of beta-(1-> 3)-D-glucan in the prepared hericium erinaceus polysaccharide is larger than or equal to 55%, the immunocompetence (IC50) reaches 32 micrograms / mL, the hericium erinaceus polysaccharide is remarkably superior to commercially available products, and the hericium erinaceus polysaccharide can be directly used as functional food and medicine raw materials. The process is green and efficient, and has remarkable economic and environmental benefits.

The invention provides nano cellulose as well as a preparation method and application thereof. The preparation method comprises the following steps: (1) carrying out heating reaction on a mixed solution containing a biomass material and a eutectic solvent, and filtering to obtain fibers; (2) mixing the fiber with a solvent, and performing ultrasonic treatment to form the nano cellulose; wherein the eutectic solvent comprises a hydrogen bond donor and a hydrogen bond acceptor, the hydrogen bond donor is selected from 2-aldehyde acetic acid and / or chloroacetic acid, and the hydrogen bond acceptor is selected from choline chloride. The preparation method provided by the invention can effectively reduce the cost and energy consumption for synthesizing the nano cellulose.

The invention discloses a chlorphenesin coupling crystallization-adsorption purification method based on a deep eutectic solvent, and belongs to the technical field of chemical purification. According to the technical scheme, the method comprises the following steps: S1, mixing crude chlorphenesin with supercritical CO2, and extracting to obtain pretreated chlorphenesin; s2, dissolving the pretreated chlorphenesin in a choline chloride-glycerol DES system, adding an adsorbent after sufficient dissolution, cooling, and separating out chlorphenesin. The technical problems that an organic solvent is used in an existing chlorphenesin purification method, and the solvent is inflammable, toxic, large in dosage, long in purification time and high in energy consumption are solved, and the chlorphenesin coupling crystallization-adsorption purification method based on the eutectic solvent is safe, environmentally friendly, capable of improving production efficiency and high in product purity and yield.

The invention belongs to the technical field of plant active component extraction and purification, and particularly provides a plant extract purification method based on a deep-eutectic solvent. A plant extract purification method based on a deep-eutectic solvent comprises the following steps: firstly, crushing and grinding a plant to be extracted to obtain fine powder, then heating and uniformly mixing choline chloride, modified amino acid and lewis acid to prepare the deep-eutectic solvent, then mixing the fine powder, the deep-eutectic solvent and water according to a certain solid-to-liquid ratio, and uniformly mixing to obtain the plant extract based on the deep-eutectic solvent. And carrying out ultrasonic extraction at a certain temperature to obtain an extracting solution, and finally purifying. According to the method, the saponin component in the soapberry can be effectively extracted, the saponin yield is high, and the purity is high.

The utility model relates to the technical field of choline chloride production, and discloses a vibrating screen for choline chloride powder production, which comprises a screening box body, a feeding pipe is fixedly mounted on the wall surface of the top end of the screening box body in a penetrating manner, and a screening assembly for screening choline chloride powder is arranged in the screening box body. The screening assembly comprises a screening frame and a screening plate, a driving mechanism used for vibrating the screening frame and the screening plate is arranged on the inner wall of the rear end of the screening box body and comprises a driving motor, a driving rod and a cam, grooves are formed in the top end wall faces of the left side and the right side of the screening plate correspondingly, and positioning plates are fixedly installed in the two grooves correspondingly. Through the arrangement of the screening frame, the screening plate, the vertical rods and the first pressure springs, the screening frame and the screening plate ceaselessly bounce up and down and conduct vibration screening on raw materials, through the arrangement of the clamping mechanisms, the screening frame and the screening plate are convenient to disassemble, and therefore follow-up cleaning work can be conveniently conducted on the screening plate.

The invention provides a stepped directional extraction method of fucoidan, and relates to the technical field of extraction of active ingredients of algae. The method comprises the following steps: pretreating brown algae powder by microwaves and ultrasonic waves, mixing the pretreated brown algae powder with a deep eutectic solvent, and carrying out ultrasonic extraction to obtain algin; the eutectic solvent is composed of choline chloride and lactic acid according to the molar ratio of 1: (1-3). According to the method disclosed by the invention, a microwave-ultrasonic synergistic wall-breaking coupling deep-eutectic solvent extraction process is adopted, so that the yield of algin is increased to 73.2%, meanwhile, an additional toxic chemical chelating agent does not need to be added, the effect of effectively adsorbing heavy metal ions is achieved, and the biological safety and commercial value of the product are greatly improved.

The invention relates to a double-layer colorimetric sensing array for visually monitoring freshness of meat products in real time and a preparation method and application thereof, and belongs to the technical field of food nondestructive testing. The preparation method of the double-layer colorimetric sensor array for real-time visual monitoring of the freshness of the meat product comprises the following steps: adding carboxymethyl cellulose into water for dissolving, and adding anthocyanin to prepare an anthocyanin solution; then mixing the anthocyanin solution with the deep eutectic solvents with different concentrations, uniformly stirring to obtain a mixed solution, standing, defoaming and drying to obtain a colorimetric sensing array indicating layer; the deep eutectic solvent is prepared from choline chloride and histidine; and carrying out electrostatic spinning on the upper surface of the colorimetric sensing array indication layer by adopting an electrostatic spinning mode to obtain the double-layer colorimetric sensing array. The sensor has excellent stability and sensitivity under a high-humidity condition, and also has the advantages of good reusability, portability, visualization, no damage, biodegradability and the like.

The present application belongs to the technical field of fruit by-product processing, and particularly relates to a method for extracting cellulose, pectin and polyphenol from pear by-product. The present application utilizes the thermo-mechanical-chemical effect of steam explosion to treat the pear by-product through steam explosion, so that most of hemicellulose and lignin can be removed, and the cellulose, pectin and polyphenol can be efficiently and rapidly extracted, thereby shortening the production cycle of the cellulose, pectin and polyphenol and improving the efficiency. Furthermore, the present application uses a combination of choline chloride and ethanol as a low eutectic solvent, and compared with other types of hydrogen bond acceptors and hydrogen bond donors, the polyphenol extraction effect is the most significant. The present application provides a method for laying a foundation for further development and utilization of pear residue cellulose, pectin and polyphenol, and improves the comprehensive utilization rate of pear processing by-products.

The invention discloses self-adhesion anti-water-loss gelatin ionic gel with high ionic conductivity as well as a preparation method and application of the self-adhesion anti-water-loss gelatin ionic gel, and belongs to the technical field of polymer ionic gel. The self-adhesion anti-water-loss gelatin ionic gel with high ionic conductivity is prepared from gelatin and a non-aqueous solvent, wherein the non-aqueous solvent is a choline chloride-sodium pyrrolidone carboxylate non-aqueous solvent or a betaine-sodium pyrrolidone carboxylate non-aqueous solvent. In the preparation process, water is not added as a solvent, water loss is not likely to happen in the use process, and the stability of mechanical performance and electrical performance is easy to maintain; the gelatin ionic gel prepared by the invention has the characteristics of water loss resistance, self-adhesion, reusability, ionic conductivity, in-situ polymerization, patterning and the like, can conformally form gel on the surface of skin through an in-situ polymerization method, and has the advantages of high skin adaptability, good stretchability, high sensitivity, capability of being directly written by ink for patterning and the like.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a preparation method of a traditional Chinese medicine external preparation for arthralgia based on blood circulation promoting and blood stasis removing, which comprises the following steps: extracting ferulic acid from angelica sinensis and ligusticum wallichii by adopting a supercritical CO2 fluid extraction process; extracting safflower, frankincense and other medicinal materials to obtain a synergistic active ingredient extract; the ferulic acid is used as a first hydrogen bond donor to react with lauric acid used as a temperature-sensitive phase change hydrogen bond donor and choline chloride used as a hydrogen bond acceptor, and the temperature-sensitive bioactive ternary eutectic solvent is prepared; loading the synergistic active ingredient extract in the solvent at low temperature to form a medicine mother solution; and finally, mixing the medicine mother liquor with auxiliary materials to prepare the external preparation. Ferulic acid in medicinal materials serves as a structural unit of a functional solvent, the solvent prepared under the mild condition has biological activity and temperature-sensitive phase change characteristics, a medicine storage cavern can be formed on the skin surface in situ, long-acting slow release and efficient transdermal absorption of active ingredients are achieved, and the curative effect and safety of a preparation are improved.

The present disclosure describes topical ketorolac compositions that comprise a eutectic solvent, such as choline chloride and propylene glycol, and methods and uses thereof. The compositions of the present disclosure are capable of delivering an effective amount of ketorolac through the skin and are believed to be useful in treating inflammation and / or pain, such as gout.

The invention relates to the technical field of material testing and analysis, and discloses a quantitative determination method for effective components in a traditional Chinese medicine capsule, which comprises the following steps: mixing choline chloride and ethylene glycol to prepare a deep eutectic solvent system; the traditional Chinese medicine capsule is placed in the eutectic solvent system, a composite frequency ultrasonic field is applied, a sound pressure amplitude step is generated by alternately switching a first working frequency and a second working frequency, and the eutectic solvent system is driven to complete solvent exchange in the medicine powder micropores; according to the method, the diffusion equilibrium of a microscopic interface is broken through the physical suction effect generated by sound pressure step, a solvent saturation dead zone in the compact particles is eliminated, and on the basis of integration of extraction and purification, the extraction and purification efficiency is greatly improved. And the accuracy and the stability of quantitative response signals are improved.

The application discloses a method for preparing goldfish feed from fermented abalone viscera powder, and comprises the following steps: preparing fermented abalone viscera powder, including raw material pretreatment, strain activation, anaerobic fermentation and final treatment; preparing a formula of the goldfish feed, including fermented abalone viscera powder, spirulina powder, fish meal, soybean meal, rice bran, wheat flour, fish oil, alpha-starch, soybean lecithin, calcium dihydrogen phosphate, vitamin premix, mineral premix, betaine, garlicin, VC-phosphate, lysine and choline chloride; and preparing the goldfish feed, including accurate batching, uniform mixing, moisture adjustment and molding, grading granulation, drying and cooling and grading screening. The fermentation and feed preparation process is simplified, the complicated enzymolysis-fermentation combined process is abandoned, no professional technical personnel are needed, and the household breeders can prepare the feed through simple equipment, and the enterprises can mass-produce the feed; the formula is optimized for goldfishes in different growth stages, is suitable for multiple goldfishes such as golden goldfish and grass goldfish, and has high application flexibility.

The application belongs to the technical field of starch chemical modification, and particularly relates to a preparation method of acetylated distarch phosphate. The method comprises the following steps: mixing starch with a deep eutectic solvent composed of choline chloride, glycerol and a small amount of water, adding a phosphate crosslinking agent and a delayed-release alkalizing agent for crosslinking reaction after pH adjustment, performing acetylation reaction by adding acetic anhydride or vinyl acetate after cleaning by alcohol solvent replacement, and finally obtaining the product through neutralization, washing, dehydration and drying. The process utilizes the deep eutectic solvent to control water activity and particle structure, and combines the slow-release alkali source to maintain a stable reaction environment, so that the crosslinking and acetylation are uniformly carried out, and the side reactions and residual salt load are effectively reduced. The obtained acetylated distarch phosphate has stable substitution degree, uniform particle structure and excellent performance in freeze-thaw stability, and is suitable for multiple fields such as papermaking, textile and oil field additives.

The invention discloses a method for demethylating a lignin derivative, which comprises the following steps of: adding the lignin derivative into an acidic eutectic solvent, stirring and reacting for 0.1-72 hours at 60-200 DEG C, cooling after the reaction is finished, and extracting and separating a product by adopting an organic solvent and water. The acidic deep eutectic solvent is composed of hydrogen bond acceptor choline chloride and hydrogen bond donor p-toluenesulfonic acid, citric acid, oxalic acid dihydrate and the like, the reaction condition of the conversion process is mild, the deep eutectic solvent can be recycled, the cost is reduced, the method is environment-friendly, and the obtained demethylation product can be used as chemicals or can be further converted to prepare materials. And the method has relatively high economical efficiency and application prospect.

The invention discloses a method for preparing benzoyl peroxide gel and application, and belongs to the technical field of medicine preparation. The preparation method comprises the following steps: preparing a ternary eutectic solvent by taking choline chloride, glycerol and benzoic acid as raw materials, mixing benzoyl peroxide with the ternary eutectic solvent to obtain a benzoyl peroxide system, and mixing the benzoyl peroxide system with a gel system on the basis to prepare the benzoyl peroxide gel with relatively high stability, storage stability and antibacterial activity.

This invention belongs to the field of organic agriculture, specifically a biological agent for promoting wheat photosynthesis and its preparation method. Addressing the problems of existing biological agents having relatively simple components, low absorption and utilization efficiency by wheat ears, and a tendency to reduce nitrate reductase activity, nitrogen utilization, and chlorophyll content in wheat leaves, the following solution is proposed: the biological agent comprises the following raw materials in parts by weight: 50-65 parts of yield-enhancing amine, 15-20 parts of choline chloride, 10-15 parts of diethylaminoethanol hexanoate, 5-10 parts of brassinolide, 3-5 parts of p-chlorophenoxyacetic acid, 1-3 parts of calcium diphenylureasulfonate, 2-5 parts of trace agents, and 2-4 parts of ethylene glycol styraldehyde. The biological agent of this invention can promote better photosynthesis in wheat, enhance nitrate reductase activity, and improve nitrogen utilization.

The application discloses a method for preparing a microalgae-based CO2 solid adsorbent by using a deep eutectic solvent hydrothermal treatment, which comprises five steps, (1) preparing an algal liquid and a deep eutectic solvent; (2) mixing and stirring choline chloride and an organic acid; (3) separating after hydrothermal reaction; (4) heating under a nitrogen environment and then cooling to room temperature; (5) mixing KOH, heating under a nitrogen environment, cooling to room temperature and washing with hydrochloric acid. The porous carbon prepared by the method has a large specific surface area and an ultramicroporous structure, and the surface is rich in nitrogen and oxygen functional groups. The porous carbon obtained has a CO2 adsorption capacity of 4.50 mmol / g under the conditions of 25 DEG C and 1 bar, and a CO2 adsorption capacity of 6.14 mmol / g under the conditions of 1 bar and 0 DEG C.

The application belongs to the technical field of crop cultivation, and particularly relates to application of choline chloride and aspartic acid in improving crop yield and quality and a method thereof. The crop seed is pretreated by using a mixed solution of the choline chloride and the aspartic acid to improve the crop yield and quality. Compared with water soaking, soaking the seed by using the mixed solution of the choline chloride and the aspartic acid can significantly improve the yield and quality of mung bean, and therefore the application of the choline chloride and the aspartic acid in improving the crop yield and quality is proposed.

The invention relates to the technical field of grease processing, and discloses a method for increasing the sn-2 DHA content in schizochytrium limacinum triglyceride. The method comprises the following steps: adding a metabolic regulator into a fermentation culture solution containing schizochytrium limacinum, carrying out fermentation culture until the total fermentation time is more than 120 hours, and collecting a grease product, the metabolic regulator is selected from at least one of choline chloride, inositol and lysophosphatidic acid. According to the method provided by the invention, the lipid metabolic flux of schizochytrium limacinum can be effectively regulated and controlled, and directional enrichment of DHA to the sn-2 site of triglyceride is remarkably promoted, so that the yield and content of sn-2 DHA are improved.

The invention discloses a carbon dioxide capturing agent based on organic amine as well as a preparation method and application thereof. The carbon dioxide capturing agent is prepared from the following raw materials in parts by weight: 60 to 80 parts of organic amine, 10 to 20 parts of octanoic acid, 3 to 7 parts of carbon powder, 5 to 10 parts of urea, 10 to 20 parts of polyethylene glycol 400, 1.8 to 4 parts of polyethylene glycol monooleate, 2 to 4.05 parts of choline chloride and 40 to 60 parts of solvent. The absorption performance and regeneration effect of the capture agent on carbon dioxide can be improved.

This invention relates to a whitening extract from geranium, its preparation method, and its application, belonging to the field of plant extract preparation and cosmetic technology. The extraction method includes: preparing a eutectic solvent by mixing choline chloride and citric acid in a molar ratio of 2:1 to 4:1, and adjusting the water content to 30-70%; mixing geranium raw material powder with the eutectic solvent at a material-liquid ratio of 1:5-15 (g / mL), and performing ultrasonic-assisted extraction; concentrating the extract under reduced pressure and then freeze-drying to obtain a geranium whitening extract with a total flavonoid content of 1-4 mg / g, a total polyphenol content of 3-6 mg / g, and anthocyanin content of 1-3 mg / g. This extract can be used to prepare cosmetics or topical skin preparations with whitening, brightening, antioxidant, or pigmentation-improving effects, as well as a tyrosinase activity inhibitor. This invention provides a green and efficient method for extracting the whitening active ingredients from geranium.