156 results about "Curcuma aromatica" patented technology

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating liver depression and spleen deficiency syndrome metabolism-related fatty liver disease, which is prepared from the following raw materials in parts by weight: 8 to 10 parts of ginseng, 10 to 15 parts of radix bupleuri, 10 to 15 parts of radix curcumae, 6 to 9 parts of ginger processed pinellia, 6 to 10 parts of fructus amomi, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of semen hoveniae, 10 to 15 parts of radix rehmanniae, 8 to 10 parts of rhizoma polygoni cuspidati and 6 to 9 parts of lignum dalbergiae odoriferae. The traditional Chinese medicine composition is used for treating the metabolism-related fatty liver diseases from the aspects of liver depression, spleen deficiency and phlegm-blood stasis, starts from the core pathological chain of liver depression, spleen deficiency, phlegm-dampness and blood stasis, has the functions of soothing the liver, tonifying the spleen, resolving dampness, reducing fat and promoting blood circulation to remove meridian obstruction, and is particularly suitable for patients with liver depression, spleen deficiency and metabolism-related fatty liver diseases. Clinical tests prove that the traditional Chinese medicine composition has a good treatment effect on patients with liver depression and spleen deficiency syndrome metabolism-related fatty liver diseases, the total effective rate reaches 94% or above, and the traditional Chinese medicine composition is mild in medicine property, good in safety, stable in curative effect, not prone to relapse and suitable for being taken for a long time.

The invention discloses curcuma wenyujin sesquiterpene synthase CwTPS8 as well as a coding gene and application thereof, and belongs to the technical field of plant genetic engineering, the amino acid sequence of the curcuma wenyujin sesquiterpene synthase CwTPS8 is shown as SEQ ID NO.1, the nucleotide sequence of the gene for coding the curcuma wenyujin sesquiterpene synthase CwTPS8 is shown as SEQ ID NO.2, and the nucleotide sequence of the gene for coding the curcuma wenyujin sesquiterpene synthase CwTPS8 is shown as SEQ ID NO.1. The curcuma wenyujin sesquiterpene synthase CwTPS8 can be used for preparing beta-caryophyllene, alpha-humulene and other curcuma wenyujin sesquiterpenoids by taking farnesyl pyrophosphate FPP as a substrate, and the technology can be used for subsequently producing the sesquiterpenoids through a microbial cell factory. Meanwhile, a foundation is laid for heterologous synthesis and further development and utilization of sesquiterpenoids such as beta-caryophyllene and alpha-humulene.

This invention relates to the field of traditional Chinese medicine preparation technology, and discloses a Qingfu Chaijin granule, its preparation method, and its application. The Qingfu Chaijin granule comprises the following traditional Chinese medicine raw materials in parts by weight: Bupleurum chinense 8-12 parts, Cyperus rotundus 8-12 parts, Citrus reticulata peel 8-12 parts, Salvia miltiorrhiza 12-18 parts, Curcuma longa 8-12 parts, Angelica sinensis 8-12 parts, Ligusticum chuanxiong 5-8 parts, Foeniculum vulgare 8-12 parts, Amethyst 25-35 parts, Artemisia argyi 5-8 parts, Cistanche deserticola 8-12 parts, Epimedium brevicornu 8-12 parts, and Rehmannia glutinosa 8-12 parts. The invention also discloses the application of the aforementioned Qingfuchaijin granules in the preparation of drugs for relieving or treating dysmenorrhea caused by qi stagnation and blood stasis. By scientifically optimizing the compatibility ratio of Qingfuchaijin granules and combining it with a reasonable preparation process design, the resulting Qingfuchaijin granules have been significantly improved in terms of stability, user experience, and performance. The use of dry granulation or spray drying-dry granulation combined technology effectively reduces the initial moisture content of the granules, significantly reduces the hygroscopicity of the granules, and improves the storage stability of the product.

The invention provides a method for breeding curcuma aromatica through a liquid culture medium and application of the curcuma aromatica, and belongs to the technical field of plant culture.The method comprises the following steps that 1, curcuma aromatica seeds are taken, cleaned and then sequentially disinfected through ethyl alcohol, soaked in a sodium hypochlorite solution, soaked in sterile water and flushed, and disinfected seeds are obtained; (2) inoculating the disinfected seeds to a liquid culture medium, and performing germination culture on the sterile seeds on the liquid culture medium to obtain sterile tissue culture seedlings; and (3) cutting the sterile tissue culture seedlings into stem sections of 2-3cm, inoculating the stem sections with at least one pair of axillary buds to the liquid culture medium with the same composition in the step (2), and carrying out subculture on the tissue culture seedlings. The method provided by the invention has a good tissue culture effect on radix curcumae, can simultaneously realize excellent culture effects in four aspects of germination rate of seeds, average germination rate of tissue culture seedlings, growth height and differentiation rate, and has extremely high research value and application prospect.

The invention relates to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-15 parts of pericarpium citri reticulatae viride; 5-15 parts of szechwan chinaberry fruit; 5-15 parts of the root of three-nerved spicebush; 5-15 parts of radix angelicae dahuricae; 10-20 parts of herba lycopi; 10 to 20 parts of herba patriniae; 4 to 8 parts of frankincense; 4 to 8 parts of myrrh; 5 to 15 parts of rhizoma corydalis; 10 to 20 parts of caulis spatholobi; 5 to 15 parts of diverse wormwood herb; 10 to 20 parts of cowherb seed; 5-15 parts of radix curcumae; and 4-8 parts of fennel. The traditional Chinese medicine composition can significantly improve the symptoms of chronic prostatitis, regulate the syndromes of traditional Chinese medicine and improve the life quality of patients, and has good safety and patient compliance.

This invention relates to the field of traditional Chinese medicine (TCM) technology. The invention provides a TCM composition for treating glaucoma and its preparation method, comprising the following components in parts by weight: 18-28 parts of Cassia seed, 12-18 parts of Lycium fruit, 12-18 parts of Eriocaulon buergerianum, 10-15 parts of vinegar-processed Cyperus rotundus, 10-15 parts of mulberry leaf, 10-15 parts of Ligusticum chuanxiong, 8-12 parts of Polyporus umbellatus, 5-8 parts of Pueraria lobata, 5-8 parts of Akebia quinata, 3-5 parts of Curcuma longa, 3-5 parts of Indigo naturalis, and 2-4 parts of prepared licorice root. The TCM composition of this invention has a strong effect in lowering intraocular pressure, improving retinal blood supply, and preventing optic nerve atrophy caused by glaucoma; simultaneously, the processing method maximizes the retention of the active pharmaceutical ingredients. Furthermore, the technical solution of this invention achieves a dual improvement in efficacy and safety, and also reduces the recurrence rate and side effects.

The invention discloses a traditional Chinese medicine for treating leucoderma and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. Comprising medicine for oral administration, astragalus membranaceus, codonopsis pilosula, bighead atractylodes rhizome, rhizoma smilacis glabrae, Chinese yam, fructus psoraleae, angelica sinensis, buffalo horn shreds, dogwood, salvia miltiorrhiza, red paeony root, safflower carthamus, ligusticum wallichii, peach kernel, polygonum multiflorum, eclipta alba, white mulberry root-bark, divaricate saposhnikovia root, radix bupleuri, scutellaria baicalensis, curcuma aromatica, fingered citron, rhizoma cyperi, felwort, parched white peony root, tribulus terrestris, gardenia, radix angelicae and rhizoma typhonii. The external immersion liquid comprises fructus psoraleae, radix angelicae, cortex dictamni, radix polygoni multiflori, borax, rhizoma typhonii, semen cuscutae, flos carthami and white spirit. Through oral administration for regulating qi and blood, tonifying liver and kidney, dredging meridians and collaterals and consolidating root, external application for dredging local parts and promoting pigment, internal and external synergism and simultaneous treatment of both symptoms and root causes, the traditional Chinese medicine is especially suitable for middle-aged and elderly patients with qi and blood deficiency, deficiency of liver and kidney and qi stagnation and blood stasis type leucoderma.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for relieving depression and clearing collaterals and a preparation, a pharmaceutical composition and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 6-12 parts of radix bupleuri, 9-15 parts of radix curcumae, 6-12 parts of rhizoma acori graminei, 3-9 parts of fructus gardeniae, 3-9 parts of polygala tenuifolia, 9-15 parts of radix paeoniae rubra and 9-20 parts of cortex albiziae. The traditional Chinese medicine composition provided by the invention can be used for remarkably improving depression-like behaviors of mice with depression, reversing synaptic injury and improving the expression of synaptic associated proteins SYP and PSD-95. The anti-depression mechanism of the traditional Chinese medicine composition is that the traditional Chinese medicine composition has the effects of synergistically inhibiting activation of microglial cells and reducing the level of proinflammatory cytokines such as Tnf alpha, Il1beta and Il6, so that neuroinflammation is remarkably inhibited, and the traditional Chinese medicine composition has the advantages of novel formula, definite mechanism and definite curative effect for treating depression, particularly patients with anxiety and dysphoria symptoms.

The invention relates to an automatic preparation method and device of a medicament for treating liver cirrhosis. A traditional Chinese medicine decoction is prepared from the following raw materials in parts by weight: 10 parts of radix astragali, 5 parts of radix notoginseng, 15 parts of radix salviae miltiorrhizae, 10 parts of rhizoma atractylodis macrocephalae stir-fried with bran, 10 parts of poria cocos, 10 parts of fructus aurantii stir-fried with bran, 15 parts of vinegar turtle shell, 5 parts of vinegar schisandra chinensis, 15 parts of vinegar tortoise shell, 10 parts of peach kernel, 10 parts of radix curcumae, 15 parts of Chinese lobelia and 20 parts of phyllanthus urinaria. An automatic preparation device of the liver cirrhosis treatment medicament is applied, and the method comprises the following steps: S1, filling; s2, performing soaking; s3, decocting first; s4, group decoction; s5, later operation is carried out; s6, squeezing; a standardized decoction process aiming at a specific liver cirrhosis treatment prescription can be executed in a single container through exquisite mechanical linkage and automatic control in a whole process without manual intervention, and a specific traditional Chinese medicine formula (astragalus membranaceus, vinegar turtle shell and the like) is deeply combined with an automatic operation process of the device, so that a set of optimized preparation process is formed.

The invention relates to an Angong bezoar pill and a preparation method thereof. The Angong bezoar pill contains 0.2 part of a bionic rhinoceros horn biological agent, 0.1 part of the bionic rhinoceros horn biological agent, 0.025 part of musk, 0.05 part of pearl, 0.1 part of cinnabar, 0.1 part of realgar, 0.1 part of coptis chinensis, 0.1 part of scutellaria baicalensis, 0.1 part of cape jasmine, 0.1 part of radix curcumae and 0.025 part of borneol for compatible use. The similarity between the core chemical components of the bionic rhinoceros horn biological agent and the natural rhinoceros horn reaches 95% or above, and the composition and content of active substances meet the drug effect requirements.

The invention discloses a traditional Chinese medicine for treating haemorrhoids, which comprises the following raw materials: borneol, centipeda minima, pepper, radix sophorae flavescentis, seaweed, rheum officinale, radix curcumae, radix angelicae, perilla leaf, mint, prepared myrrh and realgar. The composition design, pathogenesis and pathology distinguishing and channel tropism logic are strict and reasonable, and the effects of relieving pain and stopping bleeding, softening hardness to dissipate stagnation, removing slough and promoting tissue regeneration and treating both symptoms and root causes can be achieved when hemorrhoids are treated. The traditional Chinese medicine composition has the advantages of simple preparation process, quick effect of relieving pain and stopping bleeding and short curing time, can be used for treating hemorrhoids at different disease positions such as internal hemorrhoids, external hemorrhoids and mixed hemorrhoids, and can also be used for treating constipation, rectocele, anal abscess, rectal cancer, anal eczema and other related anorectal diseases.

The traditional Chinese medicine comprises (1) radix puerariae, (2) radix angelicae sinensis, (3) radix salviae miltiorrhizae, (4) radix codonopsis, (5) radix astragali, (6) fructus perillae, (7) fructus ziziphi jujubae, (8) radix bupleuri, (9) radix scutellariae, (10) flos carthami, (11) radix curcumae, (12) radix et rhizoma rhei, (13) pericarpium zanthoxyli, (14) radix glycyrrhizae, (15) radix ophiopogonis, (16) fructus schizandrae, (17) radix aconiti carmichaeli, (18) radix ginseng, (19) poria cocos, (20) gypsum, (21) oyster, (22) cassia twig and (23) semen plantaginis. Or extracts of the above components, the amount of the extracts being equivalent to the amount of the raw materials of the corresponding components. The invention aims at the clinical curative effect of amyotrophic lateral sclerosis diseases with different pathological manifestations. The medicine can be combined with western medicines for use.

The invention discloses a novel traditional Chinese medicine honeyed pill for treating alopecia, and relates to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: radix rehmanniae praeparata, angelica sinensis, raw radix paeoniae alba, semen cuscutae fried with wine, radix saposhnikoviae, gastrodia elata, ligusticum wallichii, radix ophiopogonis, asparagus cochinchinensis, radix bupleuri, radix puerariae, cassia twig, radix curcumae, caulis spatholobi and other traditional Chinese medicines which are subjected to superfine grinding and then are matched according to a specific proportion. The preparation process comprises the steps of crushing; refining honey; and mixing and waking up the medicine. The traditional Chinese medicine composition has the following effects: the composition takes effect at multiple targets: up-regulating hair follicle survival promoting factors and down-regulating inflammatory mediators; the process has the advantages that the stability of pills is improved by controlling the viscosity of refined honey; the clinical application has the advantages that the cure rate of severe alopecia totalis is improved compared with the traditional prescription The recurrence rate is low after the medicine is stopped for one year. The formula is mainly used for treating alopecia, alopecia areata, sticktight and alopecia totalis.

The invention discloses a traditional Chinese medicine composition for treating anxiety insomnia. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of rhizoma coptidis, 3-6 parts of cortex cinnamomi, 5-8 parts of fructus aurantii immaturus, 5-10 parts of radix curcumae, 5-8 parts of radix polygalae, 5-10 parts of fructus schizandrae, 5-8 parts of rhizoma chuanxiong and 1-3 parts of borneol. The traditional Chinese medicine composition can be used for preparing an external preparation navel patch, and the navel patch can be absorbed through the Shenque acupoint to play a whole regulation role. The navel patch disclosed by the invention has a remarkable curative effect on anxiety emotion caused by heart-kidney disharmony and qi stagnation and secondary anxiety insomnia symptoms such as difficulty in falling asleep, vexation, insomnia, dreaminess and easy awakening, is safe and convenient to use, provides a new solution for an external treatment method of anxiety insomnia, and has relatively high application and popularization values.

The invention discloses a traditional Chinese medicine composition for treating gallstone and a preparation method thereof, and relates to the technical field of traditional Chinese medicine compositions, and the traditional Chinese medicine composition for treating gallstone is characterized by comprising the following components: lysimachia christinae hance, endothelium corneum gigeriae galli, lygodium japonicum, radix curcumae, corn stigma and szechwan chinaberry fruit. Clinical and experiments prove that the traditional Chinese medicine composition can effectively eliminate clinical symptoms of gallstone, and can correct liver function and dyslipidemia, relieve the inflammation level, regulate abnormal metabolism of cholesterol-bile acid, remarkably promote dissolution and discharge of gallstone and inhibit recurrence of gallstone. The traditional Chinese medicine composition not only can effectively prevent and treat gallstone and remarkably relieve clinical symptoms of patients, but also can reduce the treatment cost and avoid pain caused by operations, and has a wide application prospect.

The invention discloses a traditional Chinese medicine composition for treating fatty liver and reducing hepatitis B virus load. The traditional Chinese medicine composition is prepared from the following raw material medicines: prepared rehmannia root, rhizoma polygonati (processed), radix asparagi, schisandra chinensis, hawthorn leaf, glossy privet fruit, oriental wormwood, radix curcumae, illicium verum and salvia miltiorrhiza. According to the technology of the invention, liver treatment is a preparation based on compatibility of traditional Chinese medicine syndrome differentiation in which liver, spleen and kidney are treated at the same time, fat in the liver can be effectively removed, damage of hepatitis B virus to the liver can be reduced, hepatitis B virus reproduction can be effectively inhibited, the load of hepatitis B virus can be reduced, and multiple curative effects of liver treatment, liver nourishing and liver protection can be realized; the traditional Chinese medicine composition is superior to other treatment medicines and treatment technologies for fatty liver in modern medicine. The method can be widely applied to the fields of medicines, functional foods, health-preserving and health-care products, common foods and beverages and the like.

The invention discloses a traditional Chinese medicine ointment containing deer sinew powder and tortoise shell powder and a preparation method thereof. The traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 5-10 parts of deer sinew powder, 3-6 parts of deer tortoise shell powder, 8-12 parts of radix bupleuri, 8-12 parts of radix curcumae, 10-15 parts of spica prunellae, 10-15 parts of bulbus fritillariae thunbergii, 8-12 parts of radix angelicae sinensis, 6-10 parts of rhizoma chuanxiong, 5-8 parts of frankincense, 5-8 parts of myrrh, 100-150 parts of vaseline and 20-30 parts of beewax. According to the invention, the defects of limited effect, single curative effect, shallow action level, poor long-term effect and the like due to the adoption of conventional medicinal materials for soothing liver, regulating qi, promoting blood circulation and removing blood stasis in the use process of the existing external ointment are overcome.

The invention provides a method for identifying and detecting a phlegm stasis and arthralgia dredging prescription. The method comprises three modules of construction of a characteristic chromatogram of a medicinal material and optional thin-layer chromatography identification and effective component content determination. The construction of the characteristic spectrum adopts a diethyl ether-ethyl acetate two-stage segmented extraction UPLC analysis strategy, so that the interference of complex components is overcome, and the overall chemical characteristics of the compound can be comprehensively represented; thin-layer chromatography identification provides a specific identification method for medicines such as coptis chinensis, curcuma wenyujin and vinegar-processed rhizoma corydalis; and the content determination adopts a high performance liquid chromatography to detect the effective components chlorogenic acid, salvianolic acid B, glycyrrhizic acid and berberine hydrochloride. According to the invention, a multi-dimensional and configurable quality control system is constructed, the comprehensive quality control of the phlegm stasis and arthralgia dredging prescription from qualitative and overall characterization to quantitative analysis is realized, the specificity is strong, and the result is reliable.

The invention relates to the technical field of preparation and application of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating Alzheimer's disease and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 9-30 parts of astragalus membranaceus, 9-30 parts of codonopsis pilosula, 6-10 parts of herba epimedii, 9-15 parts of rhizoma polygonati, 3-10 parts of rhizoma acori graminei, 3-10 parts of polygala tenuifolia, 6-12 parts of dendrobe, 3-6 parts of rhodiola rosea, 3-10 parts of radix curcumae, 9-15 parts of cortex lycii radicis, 3-9 parts of Hubei fritillary bulb, 3-10 parts of radix angelicae, 3-10 parts of pericarpium citri reticulatae and 3-10 parts of fresh ginger. The traditional Chinese medicine composition provided by the invention accords with the traditional Chinese medicine treatment concept of tonifying deficiency and filling marrow, inducing resuscitation and soothing nerves, dredging collaterals and eliminating evil, and tonifying spleen and assisting transportation, not only can relieve damage of neurons, but also can reverse alzheimer disease related disorder signal channels in neuronal cells, microglial cells and astrocytes.

The application provides a traditional Chinese medicine composition for preventing and treating ketosis of dairy cows, an oral liquid, a preparation method and application thereof, and belongs to the field of veterinary products. Active ingredients of the application include the following raw materials in parts by weight: 30-40 parts of rhizoma polygonati, 20-35 parts of cortex lycii, 15-25 parts of curcuma, 15-25 parts of rehmannia glutinosa, 5-15 parts of dioscorea, 5-15 parts of chicory, 5-15 parts of taraxacum, 5-10 parts of motherwort, and 5-10 parts of citrus reticulata. The composition of the application is reasonably matched, has synergistic effects, fully plays the role of each medicine, and has obvious effects on preventing and treating ketosis of dairy cows.

The invention relates to the technical field of pharmaceutical preparations, in particular to a myocardial protection traditional Chinese medicine composition capable of clearing heat, promoting blood circulation and removing blood stasis, a preparation and a preparation method and application of the myocardial protection traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 5-15 parts of gentiana acuminata, 10-20 parts of salvia miltiorrhiza, 5-15 parts of angelica sinensis, 10-20 parts of gynostemma pentaphylla, 5-15 parts of rhodiola rosea, 3-10 parts of hematoxylon, 5-15 parts of radix paeoniae rubra, 3-10 parts of lumbricus, 3-10 parts of radix curcumae, 10-20 parts of astragalus membranaceus, 3-10 parts of ginseng, 5-15 parts of radix ophiopogonis, 3-8 parts of schisandra chinensis and 3-8 parts of liquorice. According to the traditional Chinese medicine compound provided by the invention, through the synergistic effect of clearing heat, promoting blood circulation, removing blood stasis, tonifying qi and nourishing yin, the synergistic effect can be achieved more comprehensively aiming at the pathogenesis of heat-blood stasis intermingling. The traditional Chinese medicine composition has remarkable advantages in the aspect of treating myocardial ischemia reperfusion injury, the curative effect of the traditional Chinese medicine composition depends on complete monarch, minister, assistant and guide compatibility, and the overall medicine effect can be reduced if part of components are lost.

The application provides a method for breeding radix curcumae in liquid medium and application thereof, and belongs to the technical field of plant culture. The method comprises the following steps: (1) taking radix curcumae seeds, washing, and then sequentially using alcohol disinfection, sodium hypochlorite solution immersion, sterile water immersion and washing to obtain disinfected seeds; (2) inoculating the disinfected seeds into liquid medium, and culturing the sterile seeds on the liquid medium to obtain sterile tissue culture seedlings; (3) cutting the sterile tissue culture seedlings into stem segments with a length of 2-3 cm, each of the stem segments having at least one pair of axillary buds, and inoculating the stem segments into the liquid medium of the same composition in step (2) to carry out tissue culture seedling subculture. The method has good tissue culture effect on radix curcumae, can simultaneously achieve excellent cultivation effects in the germination rate of seeds, the average germination rate of tissue culture seedlings, the growth height and the differentiation rate, and has high research value and application prospect.

The invention discloses a curcuma aromatica quality prediction method and system based on morphology and chromaticity, relates to the technical field of traditional Chinese medicine quality detection, and aims to solve the problem that an existing quality evaluation method cannot realize rapid, objective and scientific field quality evaluation. The method comprises the following steps: S1, acquiring form dimension data and component dimension data; s2, carrying out correlation analysis on the acquired data, and determining a correlation rule between a morphological chromaticity index and a chemical index; s3, taking the form dimension data as input and the cost dimension data as output, and constructing a prediction model which comprises an original feature model and an enhanced feature model; and S4, dynamically allocating weights of the original feature model and the enhanced feature model, and performing weighted average on prediction results of the original feature model and the enhanced feature model to obtain a prediction value. According to the method, the curcuma aromatica quality evaluation can be rapidly, objectively and intelligently realized by constructing the prediction model based on the form and the chromaticity.

The invention discloses an anti-cervical cancer nano targeting tablet based on a traditional Chinese medicine compound and a preparation method thereof. The nano targeting tablet is prepared from the following raw materials in parts by weight: centipede, bungarus parvus, syngnathus, scorpio, nidus vespae, leech, ground beeltle, frankincense, myrrh, dandelion, rhizoma cyperi, radix bupleuri, fructus aurantii, cortex phellodendri, angelica sinensis, radix curcumae, poria cocos, bighead atractylodes rhizome, radix paeoniae alba, cortex albiziae, Chinese yam, oldenlandia diffusa and selfheal. According to the invention, active ingredients of the traditional Chinese medicinal materials are retained and enriched to the maximum extent through a modern extraction technology, the curative effect of the original formula is ensured to be retained to the maximum extent, and through a folic acid receptor, CD44 receptor and pH sensitive triple targeting mechanism, the medicine is enriched in cervical cancer tissues, the local medicine concentration is improved, the system toxicity is reduced, and accurate targeting delivery is realized.

This invention relates to a choleretic traditional Chinese medicine composition, its preparation method, and its application, belonging to the field of traditional Chinese medicine preparation technology. The microcapsules prepared from this choleretic traditional Chinese medicine composition consist of a core and a coating. The core contains a traditional Chinese medicine extract, pregelatinized starch, sodium alginate, and croscarmellose sodium. The coating contains hydroxypropyl cellulose and hydroxypropyl methylcellulose E5, PEG4000, and talc. The traditional Chinese medicine extract is made from Artemisia capillaris, Lysimachia christinae, Rheum palmatum, Scutellaria baicalensis, Taraxacum mongolicum, Forsythia suspensa, Curcuma longa, Curcuma longa, Bupleurum chinense, Citrus aurantium, and Aucklandia lappa. This choleretic traditional Chinese medicine composition has the effects of promoting bile flow and expelling gallstones, detoxifying and reducing swelling, with a stable drug release rate, definite efficacy, and few toxic side effects. It can be used for the prevention and / or treatment of acute and chronic gallstones and / or cholecystitis.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating lung diseases and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following raw materials: codonopsis pilosula, astragalus membranaceus, white mulberry root-bark, oyster, salvia miltiorrhiza, houttuynia cordata, loofah sponge, angelica sinensis, ligusticum wallichii, peach kernel, lumbricus, radix stephaniae tetrandrae, radix peucedani, radix stemonae, spina gleditsiae, radix curcumae and acanthopanax. Based on the'lung-intestinal axis' theory, by tonifying qi and lung, clearing heat and eliminating phlegm, promoting blood circulation and dredging collaterals, relieving cough and asthma and remodeling intestinal flora of a patient, the level of inflammatory factors is reduced, and the risk of acute exacerbation is reduced. Clinical application shows that the traditional Chinese medicine composition can effectively improve the clinical symptoms of patients, reduce the levels of IL-1beta, IL-6 and TNF-alpha and regulate the intestinal flora structure, and has good treatment potential.

The application discloses a traditional Chinese medicine composition for treating coronary heart disease combined with anxiety and depression and a preparation method of the traditional Chinese medicine composition. The composition comprises the following components in parts by weight: American ginseng powder 3-10 parts, panax notoginseng powder 3-6 parts, amber powder 1-2 parts, curcuma zedoaria powder 3-10 parts and hypericum perforatum powder 1-5 parts. The composition can effectively treat coronary heart disease combined with anxiety and depression.

The invention provides an eighteen-ingredient turbidity-dissolving composition as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The eighteen-ingredient turbidity dissolving composition comprises the following components in parts by weight: 90 to 130 parts of astragalus membranaceus, 45 to 65 parts of ginseng, 45 to 65 parts of poria cocos, 45 to 65 parts of bighead atractylodes rhizome, 45 to 65 parts of cortex magnoliae officinalis, 45 to 65 parts of fructus aurantii, 90 to 130 parts of radix puerariae, 45 to 65 parts of rhizoma alismatis, 45 to 65 parts of lotus leaves, 45 to 65 parts of folium mori, 90 to 130 parts of coptis chinensis, 45 to 65 parts of ginger, 45 to 65 parts of radix curcumae, 45 to 65 parts of salvia miltiorrhiza, 45 to 65 parts of hawthorn, 45 to 65 parts of semen cassiae, 45 to 65 parts of angelica sinensis and 45 to 65 parts of honey-fried licorice root. The 18 components are matched with one another and have a synergistic effect, so that the excellent technical effects of reducing blood fat and regulating the content of cAMP are achieved; the eighteen-component turbidity-dissolving composition is prepared into a medicinal preparation to be taken by patients with hyperlipidemia syndromes, and the medicinal preparation is effective in final treatment.

The invention discloses a preparation method, and particularly relates to equipment for preparing paste for relieving depression and stabilizing mind and a preparation method of the paste for relieving depression and stabilizing mind. 8 parts of radix curcumae; 12 parts of salvia miltiorrhiza; 10 parts of Chinese angelica; 8 parts of ligusticum wallichii; 15 parts of radix paeoniae alba; 5 parts of liquorice; 7 parts of fructus aurantii; 6 parts of green tangerine peel; 6 parts of pericarpium citri reticulatae; 4 parts of radix scutellariae; 4 parts of moutan bark; 10 parts of hawthorn; and 8 parts of platycodon grandiflorum. The strategy of dosing in batches and decocting in sections ensures that all the medicinal materials release effective components at the most appropriate temperature and time, and the situation that volatile components are lost due to long-time high temperature is avoided, so that the overall medicine effect extraction rate is increased. The precise temperature control, vacuum concentration and time-phased dosing strategy effectively avoids the adverse effects of high temperature, overlong decoction and other process conditions on the active ingredients, so that the drug properties of the medicinal materials are fully retained and played in a balanced manner.

The invention discloses a pharmaceutical composition for adjuvant therapy of nodular diseases and a preparation method thereof, and relates to the technical field of medicines.The pharmaceutical composition is prepared from, by weight, 1-10 parts of cordycepin, 10-20 parts of spica prunellae extract, 10-30 parts of plant extract for softening hardness to dissipate stagnation and 15-30 parts of functional auxiliary materials; the cordyceps nucleoside is a nucleoside component of which the purity is greater than or equal to 98%; the mass ratio of oleanolic acid to ursolic acid in the prunella vulgaris extract is 3: 1, and the total content of oleanolic acid and ursolic acid is greater than or equal to 12%; the hard lump resolving plant extract is an extract of thunberg fritillary bulb, radix scrophulariae, oyster powder, seaweed, kelp, radix curcumae and radix bupleuri; the functional auxiliary material is formed by compounding at least three of a filling agent, a disintegrating agent, a suspending aid and an adhesive according to an equal mass ratio; the multiple raw materials are scientifically proportioned to play a synergistic role, the preparation process is standardized, active ingredients are reserved, indexes of finished products are stable, and large-scale production and adjuvant therapy of the nodular diseases can be achieved.