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47 results about "Hashimoto thyroiditis" patented technology
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Furanopyridine derivatives and methods of use
The present invention relates to furanopyridine compounds having the general Formula I: and stereoisomers, tautomers, solvates, pharmaceutically acceptable salts and derivatives, and prodrugs thereof. The invention also includes pharmaceutical compositions comprising a compound of Formula I, methods of modulating Lck and ACK-1 enzymes and of treating various related diseases and conditions, including inflammation, inhibition of T cell activation, proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, Crohn's disease, lupus, hypersensitivity, type 1 diabetes, psoriasis, dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune diseases, glomerulonephritis, allergic diseases, asthma, hayfever, eczema, cancer, colon carcinoma, thymoma, just to name a few, in a mammal, comprising administering to the mammal a therapeutically effective amount a compound of Formula I, as described above, and methods of manufacturing medicaments comprising the compound of Formula I.
Owner:AMGEN INC
Traditional Chinese medicine combination for treating hashimoto thyroiditis
InactiveCN102670915AProtectiveHas a repairing effectImmunological disordersPlant ingredientsSide effectBefore Breakfast
The invention provides a traditional Chinese medicine combination for treating hashimoto thyroiditis and relates to the technical field of medicines. The traditional Chinese medicine combination for treating the hashimoto thyroiditis is characterized by comprising, by weight, 5-12g of Chinese Angelica, 6-12g of bupleurum, 10-20g of atractylodes macrocephala koidz, 5-15g of poria cocos, 5-7g of honey-fried licorice root, 5-15g of rhizoma cyperi, 5-10g of prunella vulgaris, 5-15g of white paeony root, 10-20g of codonopsis pilosula, 10-20g of astragalus and 10-15g of ligusticum chuanxiong. Raw materials are mixed in a casserole, and an appropriate amount of water is added to fully soak the raw materials; the raw materials is decocted with strong fire to boil, then the raw materials are decocted with soft fire, a liquid medicine is filtered out, an appropriate amount of water is added to dregs of a decoction, the dregs are decocted for half an hour, a liquid medicine is filtered out, and the liquid medicines generated twice are mixed and fully cooled and taken half an hour before breakfast and two hours after supper respectively. Various ingredients of the traditional Chinese medicine combination for treating the hashimoto thyroiditis are pure traditional Chinese medicines which can soothe the liver, regulate vital energy, strengthen spleen, nourish blood, promote blood circulation to remove blood stasis and soften hardness to dissipate stagnation when combined to be used, the protecting and restoring effects on a thyroid gland tissue are achieved, symptoms of a patient are effectively relieved, the effective rate is 92.5%, and adverse reactions and toxic and side effects are avoided.
Owner:王中英
Traditional Chinese medicine for treating Hashimoto's thyroiditis
InactiveCN101152536ALow costCompatibility is simpleDrug compositionsPlant ingredientsDiseaseTreatment effect
A traditional Chinese medicine for curing hashimoto's thyroiditis belongs to a traditional Chinese medicine for curing swollen masses goiter. The components contain: 9g of Chinese thorowax root, 9g of turmeric root tuber, 9g of nutgrass galingale rhizome, 9g of Baical Skullcap Root, 12g of Akebia Fruit, 12g of Bidens bipinnata L., 12g of Tuckahoe, 12g of Peach Seed, 30g of Milkvetch Root, 30g of Isatis Root, 20g of dried date and 6g of sward. The substances in the prescription are made from natural traditional Chinese medicine plus traditional preparing methods. The materials are easy to collect, the prescription and the preparation methods are simple, and the cost of medicine preparation is low. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from hashimoto's thyroiditis, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.
Owner:尹克华
Enzyme-linked immunosorbent assay kit for quantitatively detecting human-serum thyrotrophin receptor antibodies and detecting method
InactiveCN102735850AImprove positive detection rateRealize quantitative determinationBiological testingPhosphateThyroid disorder
The invention discloses an enzyme-linked immunosorbent assay kit for quantitatively detecting a human-serum thyrotrophin receptor antibody and a detecting method. The kit contains a 96 ferment plate precoated with segment fusion protein at the carboxyl terminal of the extracellular domain of a recombinant human thyroid stimulating hormone receptor and the following bottled reagents: phosphate bleaching liquid, confining liquid, sample diluents, thyrotrophin receptor antibody standard liquid, goat-anti-human IgG second antibody labeled with horse radish peroxidase, chromogenic substrate (tetramethyl benzidine), reaction stopping solution and quality-control serum. The invention has the advantages that the detected human-serum thyrotrophin receptor antibodies give priority to a thyroid stimulation blocking antibody, the positive detection rate to patients with hashimoto thyroiditis is high, the detected result is accurate and objective, the method is simple and convenient, and the promotion and the application are easy. The invention has an important significance in diagnosis, guide therapy and curative effect evaluation of the autoimmune thyroid disorders, and has an important clinic reference value in plan making and method selection for treating Graves disease.
Owner:GENERAL HOSPITAL OF TIANJIN MEDICAL UNIV
Medicine for treating hashimoto thyroiditis
InactiveCN103908641ASave antibodyImprove the quality of lifeUnknown materialsImmunological disordersClinical trialAntibody
The invention relates to a medicine for treating hashimoto thyroiditis. The medicine is prepared to a conventional oral preparation from the following components in parts by weight: 30-40 parts of astragalus membranaceus, 15-20 parts of radix curcumae, 15-25 parts of moutan barks, 15-20 parts of curcuma zedoary, 15-20 parts of thunberg fritillary bulb and 30-40 parts of turtle shells. The medicine provided by the invention has the functions of managing Qi and activating blood and reducing phlegm and resolving masses. Pharmacodynamic test and clinical and trial study verify that the medicine provided by the invention not only can reduce the antibody of hashimoto thyroiditis to correct metabolic disorders, but also can relieve unwell symptoms to improve the living quality. The medicine is remarkable in effect of treating hashimoto thyroiditis.
Owner:SHANXI PROVINCE CHINESE MEDICINE RES INST
Oral medicine for treating thyroiditis
The invention discloses an oral medicine for treating thyroiditis. The oral medicine is prepared from the following crude drugs in parts by weight: 20-30 parts of honeysuckle, 20-30 parts of dogwood, 10-20 parts of radix cynanchi bungei, 10-20 parts of plantain herb, 5-15 parts of hirsute gonostegia herb with root, 5-15 parts of hibiscus schizopetalus, 20-30 parts of flowers carthami, 20-30 parts of eucommia ulmoides, 10-20 parts of carissa spinarum L., 5-15 parts of curcuma zedoary, 10-20 parts of poria cocos, 20-30 parts of radix sophorae flavescentis, 5-15 parts of turtle shell, 5-15 parts of root of Chinese pulsatilla and 10-20 parts of seed of cowherb. The oral medicine for treating thyroiditis disclosed by the invention is mainly used for treating hashimoto thyroiditis, and is orally taken twice a day in the morning and evening during treatment; the oral dosage is 5g; 15 days are taken as a treatment course; and the thyroiditis can be cured after 3-4 treatment courses in general.
Owner:徐小琳
Traditional Chinese medicine for treating hashimoto thyroiditis and preparation method thereof
The invention relates to traditional Chinese medicine for treating hashimoto thyroiditis and a preparation method thereof. The traditional Chinese medicine for treating the hashimoto thyroiditis is prepared from, by weight, 8-22 parts of Chinese thorowax roots, 13-27 parts of spica prunellae, 5-17 parts of combined spicebush roots, 4-13 parts of fructus citri sarcodactylis, 3-11 parts of thunberg fritillary bulbs, 13-28 parts of figwort roots, 15-26 parts of radix rehmanniae, 12-27 parts of radix paeoniae alba, 10-26 parts of milkvetch roots, 6-16 parts of angelica sinensis, 5-15 parts of spina gleditsiae, 10-21 parts of herba taraxaci, 6-15 parts of folium isatidis, 5-13 parts of clematis roots and 6-14 parts of radix platycodonis. Water is added in a mixture of Chinese thorowax roots, combined spicebush roots, fructus citri sarcodactylis and angelica sinensis, distillation is conducted to extract volatile oil, inclusion of beta- cyclodextrin is conducted on the volatile oil for standby, dregs of a decoction is mixed with other drugs after distillation, water is added in the mixture, concentration is conducted after the mixture is decocted, concentration is conducted after alcohol precipitation is conducted on a concentrated solution, auxiliary materials are added after concentration, spray drying is conducted, and mixing and granulation are conducted on drug powder, a beta-cyclodextrin inclusion complex of the volatile oil and the like. The traditional Chinese medicine for treating the hashimoto thyroiditis has the effects of regulating Qi, smoothing depression, dissipating phlegm, clearing heat, resolving lumps and removing galls.
Owner:SHANDONG PROVINCIAL HOSPITAL
Use of bulbus fritillariae total alkaloid extract in preparing medicines or health products for preventing and treating Hashimoto thyroiditis
InactiveCN108904685AImprove securityGood curative effectImmunological disordersEndocrine system disorderPharmaceutical drugFritillaria sinica
The invention discloses a new application of bulbus fritillariae total alkaloid extract in preparing medicines or health products for preventing and treating Hashimoto thyroiditis. The bulbus fritillariae total alkaloid is bulbus fritillariae cirrhosae total alkaloid extract and / or sinkiang fritillary bulb total alkaloid extract. The new application proves that the bulbus fritillariae total alkaloid has a good pharmacological function in treating the Hashimoto thyroiditis, the bulbus fritillariae total alkaloid can be used for preparing the medicines or health products for treating the Hashimoto thyroiditis, and a good clinical application prospect is achieved.
Owner:上海复活石医药科技有限公司
Traditional Chinese medicine composition for treating hashimoto thyroiditis
InactiveCN104667172AImprove clinical symptomsAbundant raw materialsInanimate material medical ingredientsImmunological disordersVerbenaTangerine Seed
The invention relates to a traditional Chinese medicine composition for treating hashimoto thyroiditis. By adopting the traditional Chinese medicine composition, the medication problems caused by hashimoto thyroiditis treatment can be effectively solved, and a technical scheme for solving the problems is that the traditional Chinese medicine composition comprises the following components in parts by weight: 12-25 parts of Chinese thorowax root, 10-30 parts of turmeric root-tuber, 10-30 parts of fruit-spike of common selfheal, 10-40 parts of tangerine seeds, 10-30 parts of dragon bone, 10-30 parts of oyster, 10-30 parts of manyflower solomonseal rhizome, 10-30 parts of lotus seeds, 5-20 parts of European verbena, 5-25 parts of Chinese trumpetcreeper flower and 5-20 parts of twig of winged euonymus; and a preparation method of the traditional Chinese medicine composition comprises the following steps: crushing the components into powder, and uniformly mixing. The traditional Chinese medicine composition disclosed by the invention is rich in raw material and scientific in compatibility, follows a prescription formulating principle of monarch, minister, assistant and guide, can support each other, has the effects of soothing the liver and regulating qi, softening hardness and dissipating stagnation, activating blood and dissolving stasis, and dredging collaterals, can be used for effectively improving clinical symptoms of patients suffering from hashimoto thyroiditis, ensures that the purpose of treating hashimoto thyroiditis can be achieved, is convenient to take and good in effect, and is an innovation of medicines for treating hashimoto thyroiditis.
Owner:HENAN UNIV OF CHINESE MEDICINE
Medicinal composition for treating Hashimoto's thyroiditis, and preparation method and use thereof
ActiveCN107158084AClear treatment effectCraft economyImmunological disordersEndocrine system disorderIn vivoActive ingredient
The invention belongs to the fields of traditional Chinese medicines and natural medicine pharmaceuticals, and concretely relates to a medicinal composition for treating Hashimoto's thyroiditis, and a preparation method and a use thereof. The medicinal composition for treating Hashimoto's thyroiditis comprises, by weight, 1 part of snakegourd peel and 1-20 parts of dried figs. The snakegourd peel and the dried figs are preferably selected according to the above weight proportions, and are processed through steps to prepare polysaccharide extract, and pharmaceutically-acceptable or health product-acceptable auxiliary materials are added to prepare a conventional oral preparation. A result of experiments of in vivo and in vivo anti-thyroid cancer pharmacological effects of the extract shows that the polysaccharide extract can reduce the high-titer autoantibodiesTGAb and TPOAb of HT, reduce IL-2, increase IL-4, inhibit the hyperthyroidism of Th1 cell functions and promote the drift of Th1 to Th2 in order to alleviate the Hashimoto's thyroiditis.
Owner:SICHUAN UNIV
Traditional Chinese medicine preparation for treating hashimoto thyroiditis
InactiveCN105381418AProtectiveHas a repairing effectDispersion deliveryUnknown materialsSide effectPatients symptoms
Owner:QINGDAO CHANGANDA PHARMA IND CO LTD
Traditional Chinese medicine composition for treating Hashimoto's thyroiditis
InactiveCN105477493AProtectiveHas a repairing effectUnknown materialsEndocrine system disorderSalvia miltiorrhizaSide effect
The invention discloses a traditional Chinese medicine composition for treating Hashimoto's thyroiditis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 33-46 parts of knoxia root, 31-39 parts of sauropus spatulifolius, 25-36 parts of raw rehmannia root, 22-29 parts of antler, 18-27 parts of salvia miltiorrhiza, 12-27 parts of radix phytolaccae, 8-16 parts of radix linderae, 5-12 parts of kaempferia galamga, 3-9 parts of radix bupleuri, 4-12 parts of atractylodes macrocephala and 5-13 parts of pinellia tuber. According to the traditional Chinese medicine composition for treating the Hashimoto's thyroiditis, various ingredients are all pure traditional Chinese medicines, which have the effects of soothing liver and regulating Qi, invigorating spleen and nourishing blood, promoting blood circulation to dispel blood stasis and softening and resolving hard mass through being used together, so that the traditional Chinese medicine composition plays roles in protecting and repairing thyroid tissue, the symptoms of patients are effectively improved or relieved, the aim of treating early-phase and no-thyroid-dysfunction-accompanied Hashimoto's thyroiditis is achieved, and no adverse reaction and toxic or side effects is caused.
Owner:QINGDAO CHANGANDA PHARMA IND CO LTD
Pharmaceutical composition for treating hashimoto thyroiditis and preparation method thereof
InactiveCN107469035ALow costNo side effectsEndocrine system disorderPlant ingredientsTreatment effectSide effect
The invention discloses a pharmaceutical composition (a formula capable of strengthening body resistance and removing stasis) for treating hashimoto thyroiditis and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of radix ginseng, 30 to 45 parts of radix astragali seu hedysari, 20 to 30 parts of radix et rhizoma salviae miltiorrhizae, 15 to 25 parts of liquorice root, 15 to 25 parts of white paeony root, 5 to 10 parts of dried tangerine peel and 5 to 10 parts of dried ginger. The pharmaceutical composition is prepared from raw materials which are both used as medicines and foods or can be used for health-care products, has no toxic side effect and has low cost. A drug effect test proves that the traditional Chinese medicine composition provided by the invention can be used for effectively repairing shapes of thyroid gland cells, reducing lymphocytes infiltration, remarkably reducing a thyroid autoantibody and a thyroid hormone level, reducing TNF-alpha (Tumor Necrosis Factor-alpha) and raising IL-10 and has a remarkable treatment effect on the hashimoto thyroiditis.
Owner:ZUNYI MEDICAL UNIVERSITY
Traditional Chinese medicine decoction for treating hashimoto thyroiditis
InactiveCN105456864AProtectiveHas a repairing effectDispersion deliveryUnknown materialsSide effectPatients symptoms
The invention discloses a traditional Chinese medicine decoction for treating hashimoto thyroiditis. The traditional Chinese medicine decoction is prepared from the following traditional Chinese medicine raw materials in parts by weight: 33 to 46 parts of radix knoxiae, 31 to 39 parts of sauropus spatulifolius beille, 25 to 36 parts of radix rehmanniae, 22 to 29 parts of cornua cervi pantotrichum, 18 to 27 parts of the root of red-rooted salvia, 12 to 27 parts of pokeberry root, 8 to 16 parts of the root of three-nerved spicebush, 5 to 12 parts of rhizoma kaempferiae, 3 to 9 parts of rhizoma cyperi, 2 to 8 parts of scutellaria baicalensis, 3 to 8 parts of honey-fried licorice root and 2 to 7 parts of herb of pilosella-leaved drymoglossum. According to the traditional Chinese medicine decoction provided by the invention, all components are pure traditional Chinese medicine and are used in combination for soothing liver and regulating Qi, tonifying spleen and nourishing blood, promoting blood circulation to remove blood stasis and resolving hard lump, the traditional Chinese medicine decoction has protection and restoration effects on thyroid tissues, can effectively relieve patient symptoms, and has no adverse reactions and toxic and side effects, the effective rate is 92.5 percent, and the aim of treating early hashimoto thyroiditis without being concomitant with thyroid dysfunctions is realized.
Owner:QINGDAO CHANGANDA PHARMA IND CO LTD
Traditional Chinese medicine for preventing and treating hashimoto thyroiditis and application thereof
The invention discloses a traditional Chinese medicine for preventing and treating hashimoto thyroiditis. The traditional Chinese medicine for preventing and treating hashimoto thyroiditis is composedof the following raw medicinal materials (by weight): 1-10 parts of Fritillaria cirrhosa (or Fritillaria pallidiflora Schrek), 0-10 parts of chinaroot greenbrier, 0-10 parts of Tripterygium wilfordiiHook f, and 0-10 parts of prunella vulgaris. In addition, the invention also discloses application of the traditional Chinese medicine in the preparation of drugs and health products for preventing and treating hashimoto thyroiditis. It shows through laboratory animal and clinical test that the traditional Chinese medicine has good safety and excellent curative effect and can effectively treat hashimoto thyroiditis. The traditional Chinese medicine has a good effect of improving clinical symptoms, has little toxic and side effect and has a good clinical application prospect.
Owner:上海复活石医药科技有限公司
Use of human amniotic epithelial cells in treatment of autoimmune disease
PendingCN110090228AGood treatment effectPluripotentCell dissociation methodsSenses disorderImmunologic disordersUveitis
The invention relates to a use of human amniotic epithelial cells (hAECs) in treatment of autoimmune disease. The invention discloses a method for treating and / or improving the autoimmune disease by using effective dose of the amniotic epithelial cells or cell preparations containing the amniotic epithelial cells alone or in combination with other drugs. The autoimmune disease includes hashimoto thyroiditis, uveitis, lupus erythematosus and the like. The amniotic epithelial cells can be given to patients by local injection or intravenous injection, the dosage range given at each time is about10<3>-10<9> cells, the shortcomings of conventional methods are made up to a certain extent, a good therapeutic effect is generated, and a new clinical treatment scheme is provided for current autoimmune diseases.
Owner:ZHEJIANG UNIV +1
Traditional Chinese medicine composition for treating hashimoto thyroiditis and preparation method thereof
ActiveCN114246918AEnhance secretory functionGood treatment effectPharmaceutical delivery mechanismFungi medical ingredientsMedicinal herbsAutoantibody
The invention belongs to the field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating hashimoto thyroiditis and a preparation method thereof. The traditional Chinese medicine composition is prepared from nine raw medicinal materials including radix astragali, rhizoma atractylodis macrocephalae, poria cocos, polyporus umbellatus, semen coicis, fructus psoraleae, herba taxilli, fructus lycii and rhizoma curculiginis, the medicine property is mild, the compatibility is precise and appropriate, the synergistic effect is achieved, and the traditional Chinese medicine composition can tonify qi, strengthen superficies, invigorate the spleen and tonify Pharmacodynamic experiments show that the composition can significantly reduce the levels of serum inflammatory cytokines IL-6 and IL-12 and the levels of serum thyroid autoantibodies TGAb and TPOAb of rats suffering from hashimoto thyroiditis, significantly improves the secretion function of thyroid, has a good treatment effect on hashimoto thyroiditis, and has good clinical application prospects. The traditional Chinese medicine composition has an exact curative effect on hypothyroidism caused by hashimoto thyroiditis, and has a wide clinical application prospect.
Owner:ZHEJIANG PROVINCIAL PEOPLES HOSPITAL
Pharmaceutic preparation for treating thyroiditis
The invention discloses a pharmaceutic preparation for treating thyroiditis. The pharmaceutic preparation comprises, by weight, 20-30 parts of honeysuckle, 20-30 parts of hairy euphorbia, 20-30 parts of rhizoma picrorhizae, 20-30 parts of poria cocos, 15-25 parts of centella, 15-25 parts of purslane, 15-25 parts of silybum marianum, 15-25 parts of radix bupleuri, 15-25 parts of eucommia ulmoides, 10-20 parts of parasitic loranthus, 10-20 parts of fructus liquidambaris, 10-20 parts of radix sophorae flavescentis, 5-15 parts of golden larch bark, 5-15 parts of radix paeoniae alba and 5-10 parts of inula herb. When the pharmaceutic preparation is prepared, only decocting with water is needed. The pharmaceutic preparation is mainly used for treating the hashimoto thyroiditis; and when treatment is carried out, the pharmaceutic preparation is orally taken two times each day, the oral dosage is 5 g, 15 days serve as one course of treatment, and the thyroiditis can be cured after treatment is carried out for 3 to 4 courses of treatment.
Owner:UNIV OF JINAN
Application of ursodesoxycholic acid
InactiveCN108451958ALower levelImprove diffuse swellingOrganic active ingredientsAntineoplastic agentsDiseaseThyroglobulin
The invention discloses the application of ursodesoxycholic acid or isomers, derivatives, medicinal salts or prodrug molecules thereof to preparation of medicines for treating and / or preventing thyroid diseases. The invention further discloses a pharmaceutical composition comprising the ursodesoxycholic acid. The ursodesoxycholic acid disclosed by the invention can achieve clinical effects of effectively lowering levels of thyroid peroxidase antibodies and thyroglobulin antibodies of patients suffering from hashimoto thyroiditis, obviously reducing thyroid nodules, improving diffuse swelling of the thyroid gland, avoiding abnormal thyroid functions and preventing thyroid cancer, is expected to become a drug for treating clinical thyroid diseases and has a very wide application prospect.
Owner:胡晨波 +1
Noninvasive detection kit for Hashimoto's thyroiditis genes
The invention provides a noninvasive detection kit for detecting Hashimoto's thyroiditis genes. The kit comprises specific primers and DNA (deoxyribonucleic acid) sequencing primers for detecting genotypes of 2 mononucleotide polymorphism sites (A49G on CTLA4 gene and C-509T on IL-4 gene), a PCR (polymerase chain reaction) reaction assembly, a PCR product purification assembly, a DNA sequencing reaction assembly and the like. The kit provided by the invention detects genotypes of 2 mononucleotide polymorphism sites closely related to generation of Hashimoto's thyroiditis to evaluate the attack risk level of Hashimoto's thyroiditis, thereby preventing the generation of Hashimoto's thyroiditis in advance. The sampling method is an oral mucosa cell sampling method which is painless and noninvasive and avoids cross infection. The method has the advantage of accurate and reliable sequencing detection result, does not need to buy expensive imported special instruments, and thus, is easy to popularize.
Owner:解码(上海)生物医药科技有限公司
A kind of medicine for treating thyroiditis and preparation method thereof
InactiveCN108250219BGood treatment effectLose weightOrganic active ingredientsOrganic chemistryDexamethasonePositive control
The invention relates to a compound with a therapeutic effect for thyroiditis, a stereoisomer, prodrug or pharmaceutically acceptable salt, pharmaceutical composition, preparation method and application of the compound. Experimental results show that the compound provided by the invention can improve the situation that the weight of mice with hashimoto thyroiditis induced by the high-iodine waterdescends obviously, and thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TGAb) increase greatly; and the experimental results show that the compound provided by the invention has good therapeutic effect on thyroiditis, particularly hashimoto thyroiditis. The therapeutic effect of the compound provided with the invention is even more remarkable compared with the therapeutic effect of a positive control dexamethasone. Therefore, the compound provided by the invention is suitable for being used as a medicine for treating thyroiditis, particularly hashimoto thyroiditis.
Owner:佳木斯大学附属第一医院
Ultrasonic image hashimoto thyroiditis identification method based on deep neural network
InactiveCN112270682AHigh precisionReduce the amount of parametersImage enhancementImage analysisPattern recognitionComputer vision
The invention provides an ultrasonic image hashimoto thyroiditis recognition method based on a deep neural network, and relates to the technical field of thyroiditis recognition. The ultrasonic imagehashimoto thyroiditis recognition method based on the deep neural network comprises the following steps: a, training a related CNN model by utilizing a thyroid ultrasonic image data set with annotation information; b, segmenting a thyroid region from the original thyroid ultrasound image by using a segmentation model; and c, inputting into the classification model to obtain a final hashimoto thyroiditis classification label. The ultrasonic image hashimoto thyroiditis recognition method based on the deep neural network has the advantages of being high in accuracy and good in generalization performance.
Owner:脉得智能科技(无锡)有限公司 +1
Acupoint application traditional Chinese medicine composition for treating hashimoto's thyroiditis and goiter
ActiveCN110179917AImprove complianceRelieve painImmunological disordersAntineoplastic agentsTaraxacum mongolicumTreatment effect
The invention provides an acupoint application traditional Chinese medicine composition for treating hashimoto's thyroiditis and goiter. The medicinal components of the acupoint application traditional Chinese medicine composition comprises the following ingredients in parts by weight of 1-5 parts of taraxacum mongolicum, 1-4 parts of iphigenia indica, 1-4 parts of clematis terniflora and 1-5 parts of angelica sinensis. The invention further provides the use of the traditional Chinese medicine composition or medicinal preparation to preparation of medicines for treating the hashimoto's thyroiditis and the goiter. According to the acupoint application traditional Chinese medicine composition for treating the hashimoto's thyroiditis and the goiter provided by the invention, through changingthe effect ways of traditional Chinese medicines, adverse reactions of medicines are reduced, the treatment effects of the medicines are reinforced, the pain that a patient orally takes the traditional Chinese medicines for a long term is reduced, and the compliance of the patient is improved.
Owner:上海市嘉定区中医医院
Traditional Chinese medicine composition for treating thyroiditis and preparation method thereof
InactiveCN113616713ASave antibodyPlay a role in reducing swelling and dispelling stagnationHeavy metal active ingredientsImmunological disordersChinese cinnamonChinese herbology
The invention discloses a traditional Chinese medicine composition for treating thyroiditis and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components: ruddle, bryozoatum, lapis chloriti, scutellaria baicalensis, wine-treated rhubarb, semen brassicae, cinnamon, radix paeoniae alba and agilawood. The ruddle, the bryozoatum and the lapis chloriti have the effects of clearing away heat and calming the liver, and calming the adverse-rising energy and reducing phlegm; the scutellaria baicalensis and the wine-treated rhubarb have the effects of clearing away heat and purging pathogenic fire; the radix paeoniae alba has the effects of cooling blood, nourishing blood and promoting blood circulation; the agilawood has the effects of depressing Qi, reducing phlegm and removing stagnation; the semen brassicae has the effects of reducing phlegm and resolving masses; and the cinnamon is used for resisting cold of the medicines. Therefore, the traditional Chinese medicine composition achieves the effects of diminishing swelling and resolving masses by a method of clearing away heat and purging pathogenic fire, reducing phlegm and resolving masses through the synergistic effect of the raw material components, and is capable of reducing an antibody of thyroiditis in serum, so that the traditional Chinese medicine composition has a good treatment effect on hashimoto thyroiditis.
Owner:王高力
A kind of capsule preparation for treating thyroiditis
The invention discloses a capsule preparation for treating thyroiditis, which is prepared from the following raw materials in parts by weight: 25 parts of honeysuckle, 20 parts of Anemarrhena, 20 parts of forsythia, 10 parts of Shegan, 10 parts of Luzon fruit, magnolia 10 parts, 15 parts of Alisma, 25 parts of white peony, 15 parts of Eucommia leaves, 20 parts of Tongcao, 15 parts of roselle, 15 parts of Scrophulariaceae, 10 parts of turtle shell, 30 parts of astragalus, and 15 parts of lotus seeds. The preparation method is as follows: taking various raw materials, mixing, adding water, decocting, filtering, adding water to the filter residue, decocting, filtering, merging, concentrating under reduced pressure, drying, and packing into capsules to obtain the product. The capsule preparation for treating thyroiditis of the present invention mainly treats Hashimoto's thyroiditis. During treatment, it is taken orally twice a day, once in the morning and once in the evening, and the oral dosage is 3 to 5 grams. 15 days a course of treatment. Generally, 3 to 4 courses of treatment can be cured.
Owner:毕学玲
Chinese medicament composition for treating hashimoto thyroiditis
The invention relates to a Chinese medicament for treating hashimoto thyroiditis. The Chinese medicament is prepared from marigold flowers, thorn langguo fruits, popcorn flowers, frangipani, knife ash trees, tangerine kernels, pinellia ternate, inula flowers, lemmaphyllum microphyllum, cortex dictamni, anise and annatto fragrance. The Chinese medicament can be clinically used for treating the hashimoto thyroiditis.
Owner:NANTONG HONGCI PHARMA
Biomarker for detecting autoantibodies with characteristics of different syndromes of hashimoto thyroiditis and application of biomarker
PendingCN113721030AConducive to revealing the essence of the syndromeConducive to revealing the molecular contentAntibody ingredientsDisease diagnosisAutoantibodyBiomarker (medicine)
The invention discloses a biomarker for detecting autoantibodies with characteristics of different syndromes of hashimoto thyroiditis and application of the biomarker. The biomarker is at least one of related autoantibodies of MAP9, IRF9, PLEKHO2, NPM3, DR1, KDM1A, PCGF2, GPCPD1 and IGBP1. The biomarkers for detecting the characteristic autoantibody of the hashimoto thyroiditis liver qi stagnation syndrome are two related autoantibodies, namely MAP9 and IRF9; the biomarkers for detecting the characteristic autoantibody of the syndrome of fire excess from yin deficiency of hashimoto thyroiditis are two related autoantibodies, namely PLEKHO2 and NPM3; the biomarkers for detecting the characteristic autoantibodies of the spleen-kidney yang deficiency syndrome of hashimoto thyroiditis are five related autoantibodies, namely, DR1, KDM1A, PCGF2, GPCPD1 and IGBP1. The serum-related autoantibody markers can reflect the syndrome characteristics of hashimoto thyroiditis, so that the traditional Chinese medicine differentiation is accurate, and the syndrome essence and molecular connotation of hashimoto thyroiditis can be disclosed.
Owner:HENAN UNIV OF CHINESE MEDICINE
A kind of traditional Chinese medicine composition and application thereof for external treatment of Hashimoto's thyroiditis and thyroid nodules
ActiveCN112807409BGood curative effectHigh acceptanceUnknown materialsDrug compositionsPharmaceutical SubstancesMirabilitum
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for externally treating Hashimoto's thyroiditis and thyroid nodules and its application. The Chinese medicine composition is composed of the following raw materials in parts by weight: 3‑15 parts of buffalo horn, 6‑30 parts of astragalus, 3‑6 parts of xanthogonia, 3‑9 parts of Arrowhead mushroom, 6‑30 parts of curcuma, 6‑30 parts of cat’s claw, 4‑9 parts of mirabilite. The present invention also includes the application of the traditional Chinese medicine composition in the preparation of medicines for treating Hashimoto's thyroiditis and thyroid nodules. Its advantages are as follows: each raw material and the weight ratio between them are optimized, and the taste of the medicine conforms to the compatibility of "junchenzuoshi". The clinical test results show that the medicine taste works synergistically with each other. When used for the treatment of Hashimoto's thyroiditis and thyroid nodules, The curative effect is good, the patient acceptability is high, and there is a good application prospect.
Owner:YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
A plasma miRNA marker related to auxiliary diagnosis of Hashimoto's thyroiditis and its application
ActiveCN106119396BImprove stabilityIncreased sensitivityMicrobiological testing/measurementDNA/RNA fragmentationDiseaseBiologic marker
Owner:朱伟
A kind of traditional Chinese medicine composition for treating Hashimoto's thyroiditis
InactiveCN104667172BImprove clinical symptomsAbundant raw materialsInanimate material medical ingredientsImmunological disordersVerbenaTwig
Owner:HENAN UNIV OF CHINESE MEDICINE
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