3 results about "Human thyroid" patented technology

A cricothyrotomy medical training device includes a ribbed tube representative of a human trachea, the ribbed tube having a first end and a second end. A first protrusion extends from the first end of the ribbed tube, the first protrusion being representative of a human thyroid cartilage. A second protrusion extends from the ribbed tube near the first end, the second protrusion being representative of a human cricoid cartilage. The second protrusion is longitudinally spaced between the first end and the second end. A first marking material is disposed at the first and second protrusions for representing a location of human skin. A second marking material disposed between the first and second protrusions to identify a location of a human cricothyroid membrane.

On the basis of a Galpha s-cAMP-PKA signal channel, which plays a normal physiological role in vivo, of thyroid stimulating hormone and the regulation and control effect of the thyroid stimulating hormone on thyroid hormone synthesis, a normal human thyroid follicular epithelial cell line Nthy-ori 3-1 is transformed into a TSHR overexpressed stable cell line for the first time, the expression quantity of TSHR in a cell membrane is obviously increased, and the TSHR expression level is improved; the response sensitivity of the Nthy-ori 3-1 cell to a thyroid stimulating hormone drug is obviously improved; by detecting the synthesis level of cAMP and thyroid hormone before and after the stimulation of the thyroid stimulating hormone, it is verified that the TSHR overexpression Nthy-ori 3-1 cell line established in the research has great superiority for determining the biological activity of the human thyroid stimulating hormone.

The invention belongs to the technical field of medicine, and discloses a novel fumaric acid-chloroacetamide compound ZWH-01 with thyroid cancer resisting activity and a preparation method thereof.The compound is simple in synthetic route, mild and environment-friendly in reaction condition and high in yield, has remarkable growth inhibition activity on human thyroid undifferentiated cancer cells 8505c, and has good application prospects. And moreover, the compound can inhibit the migration and invasion of 8505c cells in a concentration-dependent manner, and has a good application prospect.