140results about How to "Reduce fatality" patented technology

An apparatus for preventing occupant injury during accident has various features to ensure safety. A sensor 70, detecting seat belt engagement is provided. In addition, there is a means for varying the tension of a seatbelt 17, depending upon the weight of the occupant 110 and the speed of the vehicle carrying the occupant 110. When the occupant 110 seats on any of the seats 17, the load cell switch 18 will close, allowing the load cell output energy to energize the control module 25. The control module 25 will then enables the counter 50 to count the number of closed load cell switches 18. The control module 25 further enables an optoisolator switch configured with the sensor 70 to then energize a latching relay 80 operatively configured to check the seat belt latching of all occupied seats 10 with closed load cell switches 18, to assure occupants safety. The load cells are configured with strain gauges and temperature sensors to ensure human occupants. Such that, when the switch 18 for the occupied seat 10 is closed, the latching relay 80 circuit is energized so that the seat belt 17 for the occupied seat location is checked for buckling. The latching relay 80 circuit and the counter 50 circuit are operatively configured and closed only when an occupant 110 takes any of the seats 10. The latching relay switch 85 is only energized when the counter circuit 50 is closed.

An underpass under an intersection has a first underground level for pedestrians, accessible by one or more pedestrian accesses from the street level, a second underground level for vehicles, accessible by one or more vehicle accesses from the street level, wherein the first underground level enables pedestrians to safely cross a street underneath the intersection, and contains establishments for the pedestrians, and the second underground level provides vehicle parking. In an embodiment, tunnels connect the levels under adjacent intersections. An improved method has the steps of installing one or more pedestrian levels below ground having pedestrian accesses at selected street corners on the street above, installing establishments in the one or more pedestrian levels, and installing one or more vehicle levels below the pedestrian levels having one or more vehicle accesses at the side of streets above, wherein vehicle levels provide vehicle parking.

The invention relates to a carboxymethyl chitosan microsphere embolization agent. The embolization agent takes carboxymethyl chitosan as raw materials; the carboxymethyl chitosan is subjected to pretreatment, emulsification, cross-linking and dehydration drying to prepare microspheres with three-dimensional network structures. After the microspheres absorb water, the microspheres are smooth in surface and are rich in elasticity, have good biocompatibility and biodegradablity and is suitable for non-permanent vascular embolization.

The invention discloses a design way of primers for in-vitro qualitative detection of newborn inherited metabolic disease genes. The design way comprises the following steps: (1) acquiring relevant disease-causing gene information of inherited diseases: acquiring the relevant disease-causing gene information, including gene location information and mutation site information of a plurality of inherited diseases through an OMIM (Online Mendelian Inheritance in Man) database, and acquiring exon and intron information of relevant genes from an NCBI (National Center for Biotechnology Information) database according to the obtained gene information; (2) designing primers specific to the relevant genes: designing corresponding specific primers F1 and R1 specific to an exon and an exon-intron combination area of each gene. The invention also discloses the first-round PCR (Polymerase Chain Reaction) primer sequence list of syndromic deafness, a first-round PCR primer list of G6PD genes, and a first-round PCR primer sequence list of SLC12A3 genes. The primers can be used for detecting relevant genes of 22 types of common newborn inherited diseases.

A system is provided for logging failures of using seatbelts by occupants of a motor vehicle. The system includes a digital processor, a non-volatile memory, an odometer / speedometer, a clock circuit, seatbelt sensors and a passenger occupancy sensors data. The digital processor utilizes data from the odometer / speedometer for determining the distances travelled by the motor vehicle while occupants were not using seatbelts. The non-volatile memory is configured to record logs for the failures. The digital processor utilizes data from the clock circuit for counting the total times while one or more occupants were not using their seatbelts. The odometer / speedometer verifies that the failures occurred while the motor vehicle was in motion.

A device, system, and method for monitoring tire pressure of a vehicle, involving a sensor having a structure for carrying a primary current to generate a primary electromagnetic field; and a pressure target module having a structure for inducing a secondary current to generate a secondary electromagnetic field when disposed in a vicinity of the sensor during a revolutionary incident.

The invention discloses a preparation method of frozen yoghourt. The preparation method comprises the following steps of: (1) milk preparation: adding skim milk powder, cane sugar, trehalose, sodium glutamate, colloid stabilizer and essence into water to prepare milk; (2) homogenization; (3) sterilization; (4) cooling; and (5) adding direct lactic acid bacteria the weight of which accounts for 0.001-0.5% of the overall weight of the milk to the milk which is processed in the step (4), thus obtaining yoghourt after fermentation for 4-72 hours at the temperature of 37-44 DEG C. The preparation method has the following advantages that after freezing storage, the character of the yoghourt is stable after the yoghourt is unfrozen and no flocculence of protein exists; the original shelf life of the yoghourt is prolonged; the fatality rate of lactic acid bacteria of the yoghourt is reduced during freezing storage and unfreezing.

The invention relates to preparation and application of Dendrobium officinale, aiming to provide preparation of a medicine using Dendrobium officinale polysaccharide as a drug effective component, and application of the medicine for preventing or treating hypertension and apoplexy. The invention discloses the application of Dendrobium officinale in preparation of the medicine for preventing and treating hypertension or apoplexy, and extract, granules, tablets, capsules and oral liquid based on the polysaccharide and preparation methods thereof. The invention proves that the Dendrobium officinale polysaccharide is the effective component of Dendrobium officinale in preventing and treating cardiovascular and cerebrovascular diseases. By using the Dendrobium officinale polysaccharide as the special-purpose medicine, compared with Dendrobium officinale which is not extracted, the Dendrobium officinale polysaccharide has the advantages of quick medicine efficacy, large dose effect range and obvious effect.

An automatic generation method of a cable component optimizing structure of a mechanical and electrical product is characterized in that a wiring space of the mechanical and electrical product to be wired is discretized and preprocessed to obtain discrete points in the wiring space, giving the discrete points weight values according to usability by the usability weight method, introducing the weights into a genetic algorithm evaluation function, solving cable structures by the genetic algorithm evaluation function, using the initialized clustering method according to the characteristics of the cable structures to ensure the initialized clustering theory that all cable structures can be covered. On this basis, hybrid mutation operation of the algorithm is modified, and lethality of hybridized individuals is reduced by introducing secondary hybridization. In addition, local convergence of the algorithm is avoided by the elitism selection strategy, and the ideal cable structure of the mechanical and electrical product is obtained. The automatic generation method solves the field of research and development of the mechanical and electrical products, labor and material source waste and low efficiency caused by too much dependency on experience in cable design are avoided, and the algorithm is efficient and feasible.

System and method for generating notifications when a person is in a driving state, in a non-driving state, and optionally a destination arrival notification so that interested parties, such as family members, friends and / or co-workers, can make informed and proactive decisions to not call or text the person while driving is described. With push notifications, interested parties can thus make informed decisions and purposely delay making a phone call or texting a driver until after they have arrived at their destination and are no longer driving. As a result, drivers are not needlessly distracted, significantly improving road safety.

The relative position of one vehicle vs. another vehicle, both driving in a vehicular environment, is determined using vehicular communications based on the IEEE 802.11 standard. The relative position determination is performed in a measuring vehicle using data provided by a measured vehicle through IEEE 802.11 communications carried through beacons as well as GPS or other location data and local map information

The invention provides a RNA probe capable of simultaneously detecting multiple neonatal hereditary diseases and a qualitative detection method in vitro of multiple neonatal genetic metabolic diseases, and the detection method provided by the invention is used for reducing the detection cost. Specifically, the invention discloses a RNA probe capable of simultaneously detecting multiple neonatal hereditary diseases, and the design method of the RNA probe comprises the following steps: 1) obtaining exon regions of genes corresponding to the neonatal genetic metabolic diseases; 2) regulating an oligonucleotide design principle. 1760 oligonucleotide sequences of the RNA probe provided by the invention are specifically as shown in table 1. The invention further provides a kit containing the RNA probe, and the kit can be used for simultaneously detecting multiple neonatal hereditary diseases.

The invention discloses a human serum amyloid A1 and a preparation method and an application thereof. The invention further discloses a polymer of the human serum amyloid A1 and a polypeptide fragment of the human serum amyloid A1. The human serum amyloid A1, the polymer and the polypeptide fragment disclosed by the invention have the capabilities of inhibiting the expression of inflammatory cytokines, and can be used for inhibiting inflammations and treatment inflammation-relevant diseases.

The invention discloses a compound heartleaf houttuynia herb bacteriostatic Chinese medicinal film and a preparation method thereof. The Chinese medicinal film consists of the following components in part by volume: 15 to 25 parts of chitosan, 5 to 100 parts of Chinese medicinal active ingredients and 1 to 2 parts of glycerin, wherein the Chinese medicinal active ingredients comprise the following raw materials in part by volume: 28 to 55 parts of heartleaf houttuynia herb extract, 20 to 40 parts of Mongolian dandelion herb extract and 5 to 15 parts of Chinese gall extract. The Chinese medicinal film has different degrees of bacteriostatic effects on staphylococcus aureus, staphylococcus epidermidis and Escherichia coli.

The invention relates to a preparation method of a chitosan microsphere. The preparation method of the chitosan microsphere comprises the following concrete steps: causing an oil phase to flow at a certain flow rate in an oil phase pipeline; vertically injecting a chitosan aqueous phase into the oil phase pipeline from an aqueous phase pipeline at a low speed; separating the chitosan aqueous phase into liquid drops with uniform size by virtue of a shearing force of an oil phase fluid, wherein the liquid drops flow into a container filled with crosslinking agent emulsion along with an oil phase; crosslinking and solidifying to obtain microspheres while stirring; and separating and drying, so that the chitosan microsphere is obtained. The chitosan microsphere prepared by adopting the preparation method has the characteristics of small particle size and high uniformity, safety and effectiveness of embolism in an interventional therapy can be improved, clinical operability can be enhanced, the clinical safety accident rate can be reduced, excessive screening is not needed to be carried out on the chitosan microsphere product to remove microspheres which are not in target particle size, the production cost is reduced, and the production efficiency is improved.

The invention relates to chitosan microspheres. The microspheres are solid spheres which have smooth surface and uniform granularity and are formed by crosslinking of chitosan and a crosslinking agent, wherein the grain diameter of each microsphere is 50-1200 mu m, preferably 50-600mu m, and further preferably 150-300mu m; and the grain diameter difference is not more than 20 percent, and preferably not more than 10 percent. The microspheres provided by the invention have the characteristics of small grain diameters and high uniformity, and are capable of improving the safety effectiveness of embolism in interventional therapy, reinforcing the clinical operability, reducing the clinical safety accident rate and reducing the production cost.

The invention discloses a preparation method of magnetic chitosan nanoparticles and application of the magnetic chitosan nanoparticles. The magnetic chitosan nanoparticles are synthesized by tightly encapsulating superparamagnetic particles with water-soluble chitosan. The magnetic chitosan nanoparticles disclosed by the invention are simple, environment-friendly and fast in synthesis; the size and the magnetic-particle covering amount can be regulated and controlled; the magnetic chitosan nanoparticles have relatively high biocompatibility and stability; and considered from the size and the relaxation rate, the magnetic chitosan nanoparticles have relatively large application potential in the medical fields of early diagnosis of tumors and evaluation of image tracking curative effects as a magnetic resonance imaging contrast agent.

A triangular retractable safety marker provides motorists and motorcyclists with advance warning of disabled vehicles and / or work zone areas. The device has been designed to withstand reasonable winds through the use of two base supports, a lower portion and two sets of lower, middle and upper risers. The risers allow for the device to easily expand to height consistent with traffic engineering design standards for triangles when in operation and then compact when it is in storage. The two base supports in are designed not only to provide the necessary structural stability but to also open and close about the retractable risers thus providing for additional compactness. The upper part of the lower portion along with the two sets of lower, middle and upper risers have reflective decals affixed to them to correspond with standard triangle design.

System and method for generating notifications when a person is in a driving state, in a non-driving state, and optionally a destination arrival notification so that interested parties, such as family members, friends and / or co-workers, can make informed and proactive decisions to not call or text the person while driving is described. With push notifications, interested parties can thus make informed decisions and purposely delay making a phone call or texting a driver until after they have arrived at their destination and are no longer driving. As a result, drivers are not needlessly distracted, significantly improving road safety.

The invention relates to an application of antifolic in constructing a mouse model with neural tube defects (NTDs). Specifically, an anti-folic acid metabolism drug is adopted for intervening a pregnant mouse to generate folic acid dysbolism and cause abnormal embryonic development of the mouse, thereby constructing a mouse model with NTDs. The method adopted by the invention has simplicity of operation, good repeatability, high teratogenesis rate and stable effect, and simulates an animal model close to human on the pathogenesis of NTDs by obstructing normal metabolism of folic acid, thereby facilitating further studies on congenital anomalies, especially NTDs.

A portable distress light signal device generates a visual S.O.S. distress signal indication visible from a significant distance away. Indicia including the letters “SOS” are disposed on either side of the device. A first set of light emitting diodes (LEDs) are disposed on both sides of the unit, each positioned within the interior of the region defined by each letter of the “SOS” indicia. A second set of LEDs, preferably of substantial power and luminosity, is likewise disposed on both sides of the unit, within the interior of the “O” portion of the “SOS” indicia. A power cord and power plug couples the unit to a source of electrical power, such as the cigarette lighter socket or 12-Volt accessory socket of an automobile or other vehicle. Powerful permanent magnets are preferably disposed about at least the bottom and right side edges of the housing, permitting the driver of an automobile to rapidly secure the unit to a ferromagnetic surface of the vehicle, such as the driver-side door or roof, in both cases with the SOS indicia oriented in horizontal orientation for easy recognition by passersby. Hazard warning stripes are disposed about the front and back sides of the housing for further enhanced visibility. Upon the application of power to the unit, an internal microcontroller repeatedly switches power to both the first and second sets of LEDs on and off causing them to pulse in a repeated sequence that corresponds to the S.O.S. signal in international Morse code.

The invention discloses a cerebral stroke CT image segmentation method, which comprises the following steps of: overturning an ischemic cerebral stroke CT image, and preprocessing an original CT image and the overturned CT image; constructing twin multistage encoders, calculating the feature difference of each stage of the two encoders by a calculation module, and fusing features by using a multistage feature fusion module; constructing a shared decoder; designing a joint loss function, and training an optimal segmentation model on the training set; and finally, performing ischemic cerebral apoplexy infarction segmentation on a test set of an unknown segmentation label by using the trained segmentation model. According to the invention, the feature difference calculation module is used to calculate the feature difference of each level of two encoders, and the multi-level feature fusion module is used to fuse the global and local features; the infarction in the CT image can be accurately segmented, and technical support and reference are provided for improving the ischemic stroke diagnosis efficiency and accuracy and reducing the fatality rate and disability rate.

The invention relates to a preparation method of an Alzheimer's disease animal model. The method comprises the following preparation steps: siRNA using animal brain abcg4 as target gene is designed; through the experiment, the target sequence of the specific siRNA which can interfere the expression of abcg4 is GTGAGAAGCAAGAGGTGAA, the siRNA is dissolved with PBS; and an healthy animal is selected, 240mu g / kg (weight) of siRNA is injected in the lateral ventricle of the animal once by using a stereotaxic apparatus, and the animal model is obtained after 48 hours. By adopting the method for preparing the animal model, the time is short and the damage to the experimental animal is not serious.

The invention provides a method of preparing an osteoporosis model of a zebra fish and an alizarin red dyeing method thereof. According to the modeling method provided by the invention, a juvenile zebra fish or an adult zebra fish is treated by using a high concentration Fe<3+> solution to obtain the osteoporosis model. The model has obvious and prominent characteristics of osteoporosis, and can be used for screening various drugs for treating osteoporosis in a broad spectrum. The dyeing method provided by the invention optimizes the alizarin red dyeing method of the juvenile zebra fish or the adult zebra fish, and the dyeing effect of the zebra fish, especially the adult zebra fish, is improved, so that the adult zebra fish can be used for preparing the osteoporosis model.

The invention discloses an application of baicalein to the preparation of a drug for preventing and / or treating nasopharyngeal carcinoma. The application firstly proves that baicalein can remarkably inhibit a viral protein EBNA1 on which an Epstein-Barr virus exists, and a cell can become a normal cell due to tumor virus loss caused by overlow existing quantity of the protein in the cell. Baicalein can be favorably used for treating precancerous lesion, the conversion of severe rhinitis to nasopharyngeal carcinoma is effectively stopped, and the application has important significance for treating the precancerous lesion of nasopharyngeal carcinoma and reducing the occurrence rate and fatality rate of nasopharyngeal carcinoma.

The invention discloses an early gastric cancer screening system and method. The system comprises a questionnaire analysis module, a gastric function quadruple analysis module, a historical analytical result query module, a user permission management module and a login password changing module. Through the system, it is possible for rural common doctors to carry out professional screening and evaluation of gastric cancer in association with questionnaire, and screening is fast, simple and low in cost. It is recommended that a patient under high questionnaire risk to take a blood test and an examination for four gastric functions, scoring is made according to examination results, and the gastric cancer risk level is then comprehensively evaluated in connection with the score of the questionnaire; through the method, it is possible to effectively and quickly screen patients under high gastric cancer risk, it is possible to effectively increase the utilization rate of medical resources based on reduced medical burden of people, and the system and method are significant to the increase in diagnostic and cure rate of early gastric cancer and the decrease in disability rate and lethality rate.

The method relates to novel application of PAK3 as a biological marker of a neuroendocrine tumor. Through protein expression level detection of PAK3 on thymic carcinoid, pheochromocytoma, parathyroid adenoma, pituitary tumor, adrenal adenoma, cell strains of islet cell tumor, cell strains of small cell lung cancer and other neuroendocrine tumor tissues and cells, the PAK3 highly expresses and covers neuroendocrine tumors common in clinics and relates to each tissue and gland of body; the novel application initially finds that the PAK3 is relevant to tumors, in particular to the neuroendocrine tumor; the novel application discloses that the PAK3 can obviously increase the transferring capacity of the cell and shows that the PAK3 plays an important role in the developing process of the neuroendocrine tumor; and the result shows that the PAK3 can be used as the biological marker of the neuroendocrine tumor.

The invention relates to application of mycophenolate mofetil in preparing a medicine for preventing or treating the foot-and-mouth disease virus infection, and belongs to the technical field of veterinary medicines. The By means of the application, the efficient, safe and quality-controllable foot-and-mouth disease virus medicine can be provided for further controlling the spreading of the foot-and-mouth disease.

The present invention relates to a mirror and mirror system which can be used in connection with large vehicles, such as school buses, to provide the driver of such vehicles with the ability to view the entire side of the vehicle. While such vehicles currently include side view mirrors attached to the front of the vehicle, these mirrors contain blind spots, such as the area immediately in front of the rear wheel of the vehicle. The current invention overcomes such blind spots by attaching a second mirror to the rear portion of the vehicle that provides a forward view from the rear of the vehicle, including a view of such blind spots. Such front and rear mirrors may be aligned so that the view of the rear mirror is portrayed within the view of the front mirror. As such, the present invention provides the driver with a complete view of the passenger side of the vehicle.

The invention provides application of an antibiotic substitute drug melatonin in preventing the infection of meningitis escherichia coli pathogens on child patients. Meningitis-type escherichia coli is separated and identified from muscovy duck cerebrospinal fluid, a meningitis model of 3-week-old ICR mice is constructed for the first time by utilizing the strain, and the successful construction of the mouse meningitis model is evaluated from the aspects of neurological symptom scoring, mortality difference statistics, the damage degree of a blood-brain barrier, expression of meningitis-related inflammatory factors and the like respectively. With antibiotics as references, the mice are treated with the melatonin and the four combined antibiotics respectively, one week later, the disease onset conditions of the meningitis mice are detected, results show that through the melatonin and the combined use of the antibiotics, the neurological symptoms of the meningitis mice can both be reduced, the survival rate of the meningitis mice is increased, integrity keeping of the blood-brain barrier is promoted by the melatonin, the invasion of inflammatory cells into the central nervous systemis reduced, the disease onset of the meningitis in the mice is prevented through the function of the brain-gut axis, and a new antibiotic substitute and treatment strategy are provided for preventingneonatal meningitis diseases.