3 results about "Combined antibiotics" patented technology

The present invention relates to a composition for preventing or treating periodontal disease and a dental composite antibiotic ointment composition. The composition for preventing or treating periodontal disease according to the present invention comprises minocycline and metronidazole as effective ingredients.

This invention discloses a strain of *Lactobacillus johnsonii* that regulates the colonic endocannabinoid system and its applications, belonging to the field of microbial technology. This invention is the first to discover and verify that *Lactobacillus johnsonii* strain LJEH8 can significantly promote the expression of DGLβ in colonic epithelial cells and colonic tissue, thereby effectively regulating the colonic endocannabinoid system. This strain provides a new potential target and microbial resource for the prevention and intervention of intestinal diseases, and has good application prospects. Animal experiments show that in a model of intestinal flora disorder induced by combined antibiotic treatment, colonization of *Lactobacillus johnsonii* LJEH8 can significantly restore colonic DGLβ protein levels, confirming its stable and effective regulatory function in vivo.