The invention discloses an intelligent vehicle-mounted GPS (global positioning system) navigation anti-collision warning system which consists of a GPS navigation module, a speed computation module, a central processing unit, an early warning signal module, an environment sensing module, an infrared distance measuring module, a radar speed distance module, a laser distance measuring module, an ultrasound distance measuring module, an image collecting module, an information processing module, an image processing module, a tail warning device, an audio video system, a display screen and an early warning power amplifier, wherein the speed is detected by the GPS, and the distance is detected by the distance measuring module, dangers which can cause tailgating at the front and at the back of a vehicle can be founded in time, so that a driver can be warned to travel normally and drive safely, functions of GPS navigation and audio video are realized, and no part of a vehicle control system needs to be changed.