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Methods for ablation with radiant energy

InactiveUS20060253113A1Rapid and efficient creationRapid and effective photoablationStentsUltrasound therapyCoaxial catheterTarget tissue
Ablation methods and instruments are disclosed for creating lesions in tissue, especially cardiac tissue for treatment of arrhythmias and the like. Percutaneous ablation instruments in the form of coaxial catheter bodies are disclosed having at least one central lumen therein and having one or more balloon structures at the distal end region of the instrument. The instruments include an energy emitting element which is independently positionable within the lumen of the instrument and adapted to project radiant energy through a transmissive region of a projection balloon to a target tissue site. The instrument can optionally include at least one expandable anchor balloon disposed about, or incorporated into an inner catheter body designed to be slid over a guidewire. This anchor balloon can serve to position the device within a lumen, such as a pulmonary vein. A projection balloon structure is also disclosed that can be slid over the first (anchor balloon) catheter body and inflated within the heart, to define a staging from which to project radiant energy. An ablative fluid can also be employed outside of the instrument (e.g., between the balloon and the target region) to ensure efficient transmission of the radiant energy when the instrument is deployed. In another aspect of the invention, generally applicable to a wide range of cardiac ablation instruments, mechanisms are disclosed for determining whether the instrument has been properly seated within the heart, e.g., whether the device is in contact with a pulmonary vein and / or the atrial surface, in order to form a lesion by heating, cooling or projecting energy. This contact-sensing feature can be implemented by an illumination source situated within the instrument and an optical detector that monitors the level of reflected light. Measurements of the reflected light (or wavelengths of the reflected light) can thus be used to determine whether contact has been achieved and whether such contact is continuous over a desired ablation path.
Owner:CARDIOFOCUS INC

Mobile telephone having a rotator input device

A mobile telephone has a display (240) and a rotator input device (250) comprising a rotatable element and capable of generating commands for browsing and selecting objects on the display. It also has a wireless telecommunication interface to a mobile telecommunications network. A processing device is coupled to the display, the rotator input device and the wireless telecommunication interface. A text-handling software application is executable by the processing device. The processing device is configured, in a first operating mode, to provide first user input by way of the rotator input device (250), said first user input including a number sequence representative of a desired telephone number which is to be reached over the mobile telecommunications network, and to use said first user input when establishing a telephone call connection through the wireless telecommunication interface. Moreover, the processing device is configured, in a second operating mode, to provide second user input by way of the rotator input device, said second user input including a character sequence representative of a desired text, and to forward said second user input to the text-handling software application No numeric or alphanumeric character keyboard is involved in neither of the first and second operating modes.
Owner:NOKIA CORP

Methods, devices and systems for approximation and fastening of soft tissue

This invention provides minimally invasive mechanical instruments that are capable of laparoscopic or endoscopic approximation and fastening of soft tissues in a variety of interventional procedures. The devices of the present invention generally consist of a proximal handle assembly incorporating actuation means, an elongate tubular assembly (which may be flexible, rigid or combinations thereof) and a distal tool assembly incorporating mechanisms for engaging tissue at two or more spaced-apart locations on a tissue surface as well as mechanisms for deploying one or more tissue fasteners to securely hold the tissues in the approximated configuration. Typically the devices are provided in an initial collapsed (i.e. pre-deployed) configuration for insertion into the patient. After being deployed to an expanded configuration, tissue is contacted and engaged at two or more locations, and upon subsequent actuation by the user, at least one of the tissue engagement mechanisms, with tissue engaged, is repositioned by moving it toward another engaged tissue location, thereby approximating the engaged tissue locations near the distal end of the device. A variety of fasteners and fastener delivery mechanisms may be integrated into the devices of the present invention to securely and permanently hold the approximated tissues in the approximated configuration. Devices of the present invention provide surgeons the ability to carry out a variety of interventional procedures in which tissue approximation and fastening is required, in a safer and more efficient manner. Certain embodiments of the present invention enable entirely new minimally invasive tissue approximation and fastening procedures to be performed, such as closure of holes in the gastrointestinal lumen created to provide access to the abdominal cavity during natural orifice transluminal endoscopic surgery (NOTES) or laparoscopic plication gastroplasty procedures that reduce stomach volume from its external surface in the treatment of obesity.
Owner:LONGEVITY SURGICAL
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