118results about How to "Efficient replication" patented technology

Data management systems and methods that can catalog, store, and protect data from hard disk failure on a mobile or stationary computer, using a computer program and a portable data storage device are provided. The program uses a combination message-digest and check-function based algorithm that can back up, manage, and protect data independent of specific computer operating system or file system. The program can check files for block-level content changes from previously stored data blocks and catalogs and stores only new data blocks. By storing only new data blocks and cataloging information within a comprehensive, backup archive composed of these blocks, the size of each backup is reduced.

A method employing a photolithography mask for producing microtextured antireflective surfaces is disclosed. The photolithography mask is used during the exposure of photoresist to a pattern of ultraviolet light. The exposed photoresist is subsequently processed to obtain a microtextured surface possessing antireflective properties. The antireflective surface profile comprises an array of sub-micron protuberances that may reside in a periodic arrangement, a quasiperiodic arrangement, or in an arbitrary non-periodic arrangement. The antireflective surface is designed for visible light. It may be scaled-up to large areas, and is suitable for replication into inexpensive polymer materials.

The present invention provides systems and methods for efficient data storage, management, and back up. In particular, the present invention provides devices, software, and processes for efficient replication of data.

Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating the oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements.

A system and method for expediting the replication of at least one specified object to a replica in a distributed computer system. A source object of a source replica determines that it has an urgent change to propagate through the distributed system, and informs a replication facility at the source replica of the urgent change. The facility extracts, or is provided with, the change information from that object, and the source replica communicates information representative of the change to a destination replica. A replication facility at the destination replica provides the change information to a destination replica object, which uses the information to make itself consistent with the source replica object.

A method, system, computer system, and computer program product to provide an infrastructure for replicating data across multiple nodes in a network. Changes to data are written to each of a set of mirrored copies of a log on one node. When a storage area containing a portion of one of the mirrored copies of the log becomes full, the storage area is disassociated from the set of mirrored copies. After detaching the storage area, changes are no longer written to the storage area, thereby providing a stable image of that portion of the log data. Log data stored in the storage area are replicated from the storage area to another node. By replicating from a separate detached storage area, log data are replicated without disturbing the disk heads writing changes to each of the set of mirrored copies of the log.

Disclosed herein is data replication and recovery method in an asymmetric clustered distributed file system, which divides the storage space of a data server into main partitions and sub-partitions, and separately manages main chunks and sub-chunks in the main partitions and the sub-partitions, thus efficiently processing chunk replication and recovery. In the disclosed method, when a failure occurs in a data server in an asymmetric clustered distributed file system, a failed partition is reported to all data servers including other partitions of a volume to which the partitions of the failed data server belong. Accordingly, other data servers can simultaneously perform the recovery of chunks using the information of their own main chunks and sub-chunks. As a result, when a failure occurs in a data server, all related data servers can simultaneously participate in data recovery, thus more promptly and efficiently coping with the failure.

A removable medium recording station records medical image data in a format and removable medium that are widely accepted. The removable medium recording station can be used to effectively replace an installed storage device on an existing stand-alone medical image workstation. Storage onto removable media is transformed into an outboard operation. This transformation enables a hospital to migrate existing medical imaging systems to new formats and media without sacrificing a large portion of their initial investment. Additionally, the removable medium recording station can be attached as a peripheral on an existing medical modality network. In this capacity, the removable medium recording station enables an operator on the medical modality network to store medical images in a selected format and on a selected type of removable medium regardless of the proprietary format used by the enterprise level archive server. The removable medium recording station enables a hospital to add new functionality without sacrificing their investment in their enterprise solution.

A low-cost scaleable turnkey system and method for archiving medical image data. The archive system and method permits the selective storing of medical data (including image data) received from a medical modality (e.g., CT, MRI, etc.) onto a removable medium (e.g., DVD or Blu-ray), which may subsequently be placed via robotics in a magazine within the system housing. In addition to directing the archiving of the medical data as described, software components of the archive system permit a specific medium in a magazine to be addressed, retrieved, and read as needed.

A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.

A method and system is provided for copying data between two deduplicating storage systems. A list of unique fingerprints is compiled from the data which will be sent. This list is transmitted to the receiving system during a preliminary data exchange called the preamble. The receiving system replies with a second list which contains the unique fingerprints of the data which either needs to be sent or can be omitted. Which list depends on the size of the list where the smaller list is sent for efficiency and lower bandwidth consumption. A reference list of duplicate blocks being sent is retained on the receiving system until the copy operation is complete. This reference list is used to protect blocks on the receiving system by deferring deletions until the incoming hallow block can reference the duplicate block on the receiver to confirm that is on the target system and should not be deleted.

A novel HIV vaccine is provided. In particular, the vaccine comprises an avirulent and non-cytolytic recombinant HIV wherein the NSS of the virus' envelope glycoprotein is replaced with a non-cytolytic signal sequence and nef gene of the virus is deleted which renders the virus avirulent.

The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.

Recombinant human parainfluenza virus type 1 (HPIV1) compostions, formulations and methods are provided. The recombinant HPIV1 viruses and HPIV1 chimeric and chimeric vector viruses provided according to the invention are infectious and attenuated in permissive mammalian subjects, including humans, and are useful in immunogenic composition s for eliciting an immune responses against one or more PIVs, against one or more non-PIV pathogens, or against a PIV and a non-PIV pathogen. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant HPIV1 genome or antigenome.

A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.

PCT No. PCT / US96 / 07370 Sec. 371 Date Nov. 28, 1997 Sec. 102(e) Date Nov. 28, 1997 PCT Filed May 22, 1996 PCT Pub. No. WO96 / 37625 PCT Pub. Date Nov. 28, 1996Recombinant avian sarcoma leukosis virus (ASLV)-derived retrovirus vectors having an expanded host range are described. The host range is expanded by the replacement of the ASLV envelope gene by an envelope gene from a virus capable of infecting both mammalian and avian cells. The resulting recombinant ASLV-derived retroviral vectors can replicate efficiently in avian cells, infect both avian and mammalian cells in high titer, and are replication-defective in mammalian cells. Thus, they are quite safe and advantageous for use in gene therapy and vaccines.

A data replication method and a storage system are provided. The method is applied to a storage system including a first storage device and a second storage device. According to the method, after determining replication information, a first storage system determines a first replication sub-information and a second replication sub-information according to the replication information, where the replication information is used to indicate data that needs to be replicated by the first storage system to a second storage system in a current replication task. Then, the first storage device replicates data to the second storage system according to the second replication sub-information, and the second storage device replicates data to the second storage system according to the second replication sub-information. According to the data replication method, efficiency of replication performed between the first storage system and the second storage system can be improved.

A method to prepare viruses lacking ion channel activity is provided.

A hydrogen energy supply chain comprises a liquefaction factory, a low-temperature storage tank, a pump, a vaporizer, gas cylinders and hydrogen adding mechanisms. The technological process of the hydrogen energy supply chain has the technical characteristics that hydrogen gas produced through hydrogen production by a hydrogen resource place is liquefied into liquid hydrogen by the liquefaction hydrogen factory, then the liquid hydrogen is conveyed to a hydrogen user market place through a low-temperature storage tank transport means, is pressurized through the pump and is vaporized into high-pressure gaseous hydrogen through the vaporizer, the gaseous hydrogen is loaded to the gas cylinders, and then the gas storage cylinders of hydrogen fuel cells are filled completely to the rated pressure through hydrogen adding machines. According to the hydrogen energy supply chain, hydrogen liquefaction, storage, transport and other proven technologies in the aerospace field of China are used and extended to the downstream, pressurization of the pump and vaporization of the vaporizer are added for obtaining the high-pressure hydrogen gas, and the complete hydrogen energy supply chain is formed with combination of personal authorized patent technology of a gas station.

A simple and highly efficient method for cloning cDNAs including CD27 (SEQ ID NO:28) from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA libraries are disclosed. The cloning method of the invention which has been used to clone genes for cell surface antigens of human lymphocytes, has general application in gene cloning. Cell surface antigens cloned according to the present invention have been purified, and the nucleotide and amino acid sequences determined. These antigens have diagnostic and therapeutic utility in immune-mediated infections in mammals, including humans.

Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.

A method for one-to-multiple copying of data storage medium is provided, applicable to a hard disk copying system to copy the source data in a source hard disk to a plurality of target hard disks. The method includes steps of preparing a source hard disk and a plurality of target hard disks, and placing the target hard disks to hard disk receiving slots of the hard disk copying system; detecting and recording the number and addresses of the target hard disks; and copying the source data in the source hard disk to the target hard disks one by one. The method further includes steps of data compression and decompression to accelerate the data copying process.

A system and method for expediting the replication of at least one specified object to a replica in a distributed computer system. A source object of a source replica determines that it has an urgent change to propagate through the distributed system, and informs a replication facility at the source replica of the urgent change. The facility extracts, or is provided with, the change information from that object, and the source replica communicates information representative of the change to a destination replica. A replication facility at the destination replica provides the change information to a destination replica object, which uses the information to make itself consistent with the source replica object.

The invention provides a method for quickly copying cluster data in a database. According to the method, from a data copying theory of synchronizing and then processing, the atomicity and the inseparability of the database are introduced; a cluster database management device is used for separating different requests submitted by a user into structured query language (SQL) sentences of data atoms and transmitting the SQL sentences to respective servers in a cluster for executing the SQL sentences; and a final execution result is fed back to the user, so that the consistency of the data of each database server in the database cluster is ensured, and the working efficiency of the whole cluster is guaranteed. The requests submitted by the user are classified according to the atomicity and the inseparability of the database, firstly synchronized to the servers in each cluster, processed and executed by free servers in the cluster and fed back to the user, so that the data of each database server can be quickly synchronized; and therefore, the data in the cluster can be quickly copied and the servers can be efficiently managed.

Provided are methods of identifying oligonucleotides having transcriptional or translational activity by integrating ilie oligonucleotide into a eukaryotic cell genome such that the oligonucleotide is operatively linked to an expressible polynucleotide, and detecting a change in expression of the expressible polynucleotide due to the operatively linked oligonucleotide. Also provided are vectors useful for identifying an oligonucleotide having transcriptional or translational regulatory activity according to a method of the invention. In addition, isolated synthetic transcriptional or translational regulatory elements identified according to a method of the invention are provided, as are kits, which contain a vector useful for identifying a transcriptional or translational regulatory element, or an isolated synthetic transcriptional or translational regulatory element or plurality of such elements. Also provided are isolated transcriptional regulatory elements.