The invention discloses essence for a facial mask for moistureizing, replenishing water and repairing skin and a preparation method of the essence. The essence for the facial mask comprises sodium hyaluronate, a soluble protein polysaccharide solution and a saccharide isomer, can act on skin and cuticle to form a water retention protection screen, and besides, can permeate into a derma layer to promote the synthesis of sodium hyaluronate, so as to achieve double effects of moisturizing and replenishing water. The essence for the facial mask also contains natural plant extraction complex liquid, folic acid and soybean fermentation complex liquid, oat beta-glucan and ectoine. Water molecules around cells can be gathered, and a hydration housing having the effects of protecting, nourishing and stabilizing cells is formed outside a cell membrane so as to prevent cell injury. An active immunity system can be activated for reaction, collagen can be synthetized, the immunity of the cells is improved, the release quantity of mast cells and leucocyte histamine with inflammation, can be reduced; and therefore, the effects of protecting and repairing skin and muscle protection screen can be achieved. The production technology of the essence for the facial mask is simple, and large-scale industrialized production is easy to realize.