21 results about "Alizarin" patented technology

The invention provides application of linariin-6-O-glucoside in preparation of a product for preventing and treating osteoporosis, and relates to the field of biological medicine. According to the invention, dyeing experiments of alkaline phosphatase, alizarin red and tartaric acid resistant acid phosphatase prove that the sesaminin-6-O-glucoside has affinity for FPPS receptors, has the capability of promoting bone marrow mesenchymal stem cells to form bone cells, is superior to that of bisphosphate, and can inhibit the generation of osteoclasts; microCT (micro computed tomography) detection results show that the sesaminin-6-O-glucoside has the effect of relieving the osteoporosis and can promote the formation of bone trabecula. According to the application disclosed by the invention, it is proved for the first time that the sesaminin-6-O-glucoside has the effect of resisting osteoclast formation, and meanwhile, the sesaminin-6-O-glucoside also has a better osteogenesis effect, so that a basis is provided for developing the sesaminin-6-O-glucoside as a potential medicine for treating osteoporosis.

The invention relates to the technical field of cotton fabric manufacturing, in particular to a charge transfer and transition bacteriostatic pure cotton non-woven fabric and a manufacturing method thereof.The manufacturing method includes the steps that raw cotton is degreased, opened and carded, base cloth is manufactured through a spunlace method, and the pretreated pure cotton non-woven fabric is obtained after drying and impurity removing; the preparation method comprises the following steps: soaking cotton fibers into a charge transfer transition reagent containing alizarin and waterborne polyurethane, accurately loading through a four-roller unit, and curing through 254nm-365nm ultraviolet light, so that the reagent and the cotton fibers form covalent bonds to realize charge transfer transition. An ultrathin polymer film layer is formed on the cloth cover of the product, million-level electron-hole pairs are contained, the initial bacteriostasis rate exceeds 99%, and a good bacteriostasis effect is still kept after the product is washed with water for 150 times. The antibacterial non-woven fabric adopts a natural antibacterial agent, is free of skin irritation and toxic residues, is environment-friendly in production process, has skin friendliness and mechanical strength, is suitable for medical and hygienic products such as surgical gown and medical dressing, and solves the problems of poor washability, potential safety hazards and the like of the traditional antibacterial non-woven fabric.

The invention belongs to the field of intelligent degradable food packaging materials, and particularly relates to a pH response type intelligent degradable packaging film and a preparation method and application thereof. According to the invention, PBAT / PLA blended resin is used as a degradable matrix, a natural pH sensitive indicator alizarin is used as an intelligent response unit, no auxiliary component is added, and the high-performance pH response type intelligent degradable packaging film is prepared by controlling an alizarin solvent pre-dispersion-gradient mixing process and melt blending parameters. According to the invention, through collaborative proportion optimization of PBAT and PLA, the balance of flexibility and rigidity of the membrane is ensured, a uniformly dispersed microenvironment is provided for alizarin, and the core problem of agglomeration of alizarin in a hydrophobic matrix is solved. The packaging film can visually monitor the corruption degree of perishable food such as fresh chicken breast and aquatic products in real time through color change, the preparation process is simple, the cost is controllable, the safety is high, and a brand new technical path is provided for greenization and intelligentization of food packaging.

This invention discloses a method for preparing and applying a chitosan-nanofibrillar-based smart indicator membrane loaded with anthocyanins and alizarin. The method includes the following steps: mixing beet powder with hydrochloric acid, washing with water until neutral, and drying; adding sodium hydroxide solution, mixing and reacting, washing with water until neutral, and drying; adding sodium chlorite solution, mixing, adjusting the pH to 3-3.5, reacting, and washing with water until neutral to obtain beet fiber; adding water, homogenizing under ultra-high pressure to obtain a beet nano-suspension; adding the beet nano-suspension to a chitosan-acetic acid solution and stirring, then adding glycerol; adding pigments, mixing, and obtaining a membrane solution; ultrasonically degassing, and drying to form a membrane. This membrane, as a food preservation indicator membrane, possesses both the characteristics and functions of food preservation and indicating food freshness; using beet nanofibers as a supplementary material improves the mechanical properties of the chitosan membrane; the addition of alizarin and anthocyanin mixed pigments enriches the color changes of the indicator membrane and improves its stability.

The application discloses a kind of meat preservation and freshness visual double-effect nano intelligent indicating film and preparation method thereof, belong to food packaging storage and detection technical field.The preparation method of the intelligent indicating film includes the following steps: (1) poly-3-hydroxybutyric acid-co-oxyvalerate (PHBV) and ferulic acid are dissolved in chloroform solution;(2) polyvinyl alcohol (PVA), konjac glucomannan (KGM), alizarin (AL) are mixed, and polyvinyl alcohol-konjac glucomannan-alizarin mixed solution is obtained by removing bubble;(3) PH-F solution is dried by electrospinning technology, and PVA-KGM-AL@PH-F double-layer indicating film is obtained.The application prepares meat freshness indicating film with efficient antibacterial performance and high sensitivity color response performance by regulating the pH of film-forming solution.In the intelligent indicating film, alizarin responds to meat spoilage biogenic amine, and the color of indicating film gradually changes from cream (slightly yellow) to light pink or even deep purple;By comparing the intelligent indicating film after reflection with colorimetric card, the freshness of meat can be judged.

The invention discloses a food packaging film with a freshness indicating function as well as a preparation method and application thereof, and relates to the technical field of food packaging materials. According to the packaging film, the alizarin red, the lignin and the guar gum form a synergistic effect, so that the toughness of a network skeleton is remarkably improved, and the negative influence of the alizarin red on the tensile strength of the skeleton is reduced, so that the mechanical comprehensive performance of the food packaging film is favorably improved; moreover, the loading of alizarin red reduces the water vapor permeability of the food packaging film, and is beneficial to improving the barrier property of the packaging film; meanwhile, the alizarin red endows the packaging film with reversible color switching under stimulation of ammonia gas and acetic acid, and real-time monitoring of food freshness changes is achieved; the food packaging film has mechanical toughness and a proper water vapor barrier, is green and safe, has no potential toxic and side effects, can be completely biodegraded, has renewable raw materials, can significantly improve the problem of food waste caused by environmental uncertainty, and is suitable for large-scale popularization and application.

This invention relates to the field of medical dressings, and discloses a composite fiber membrane, its preparation method, and its applications. The composite fiber membrane includes a pH-responsive fiber membrane, a hydrophobic fiber membrane distributed on one side of the pH-responsive fiber membrane, and a hydrophilic fiber membrane distributed on the other side of the pH-responsive fiber membrane. The pH-responsive fiber membrane comprises polyethylene oxide, chitosan, and alizarin dye. This composite fiber membrane exhibits good antibacterial effects and unidirectional moisture-wicking function, and can also change color under different pH conditions, showing great promise for application in the field of medical dressings.

The invention discloses a preparation method of a high-precision developing antibacterial intelligent film developed based on alizarin. The preparation method of the intelligent film comprises the following steps: dissolving alizarin in an ethanol solution to obtain an alizarin ethanol solution; adding polyvinylpyrrolidone and ethyl cellulose, and uniformly mixing to obtain a shell spinning solution; mixing cinnamyl aldehyde and polyoxyethylene with water and ethanol to obtain a core layer spinning solution; and preparing the film by using a coaxial electrostatic spinning technology. According to the invention, the shell layer is a film with moderate hydrophobicity obtained by mixing a hydrophilic material and a hydrophobic material, and alizarin is added as a color developing substance, so that an obvious color developing effect is realized. Cinnamyl aldehyde is added into a core layer solution, so that the film has antibacterial and antioxidant functions; the fibers with the core-shell structure are prepared through the coaxial electrostatic spinning technology, cinnamyl aldehyde can be wrapped, release of cinnamyl aldehyde is slowed down, and the antibacterial effect of the intelligent film is enhanced.

This invention discloses a pH colorimetric membrane for indicating meat freshness, obtained through the following steps: First, konjac glucomannan and polyvinyl alcohol are dissolved separately in distilled water and heated and stirred until dissolved; then, the konjac glucomannan aqueous solution and the polyvinyl alcohol aqueous solution are mixed to obtain a film-forming solution; curcumin and alizarin are added to the film-forming solution, homogenized using a homogenizer, and then ultrasonically treated to remove air bubbles; the solution is poured into a plastic petri dish and dried in an incubator to obtain the pH colorimetric membrane. This invention uses a 3:1 mass ratio of curcumin and alizarin as colorants, resulting in stronger pH sensitivity and more obvious color changes. Furthermore, all raw materials used are derived from natural substances, are safe and non-toxic, and edible. No complex processing of meat samples is required, making the operation simple and low-cost. It has great application potential in meat freshness monitoring and intelligent packaging, and can be applied to the freshness monitoring of various meat products.

The invention relates to a hair dye, in particular to a multifunctional hair dye and a preparation method and application thereof.The preparation method comprises the following steps that S1, alizarin is dissolved in ethyl alcohol, then deionized water is added, stirring and mixing are conducted, and an alizarin ethyl alcohol water solution is prepared; s2, dropwise adding an aldehyde perfume solution into the alizarin ethanol water solution prepared in the step S1, and ultrasonically mixing uniformly to obtain an alizarin-perfume mixed solution; s3, nonferrous metal ions are dissolved in the alizarin-spice mixed solution obtained in the step S2, stirring and uniform ultrasonic treatment are carried out, and an alizarin-spice-nonferrous metal ion solution is prepared. Compared with the prior art, the hair dye disclosed by the invention solves the problem that p-phenylenediamine, ammonia water and the like commonly existing in a traditional hair dye can cause harm to a human body. According to the scheme, polyphenol and perfume are combined through a self-assembly technology to form a stable dye system, the problems are solved, and an innovative solution is provided for the hair dye.

This invention provides a standardized preparation method and kit for double-stained transparent specimens of fish skeletons. Orthogonal experiments were designed for fish of different skeleton types (cartilaginous / boneless) and body lengths (small 5-7cm, medium 7-15cm, large 15-25cm), using factors such as KOH concentration and treatment time. Staining effect, transparency, and tissue integrity were used as indicators. Statistical analysis was used to establish an optimal parameter matrix database covering fixation, transparentization, and staining steps. During preparation, the database can be queried based on fish species and body length to obtain differentiated treatment parameters, achieving standardized operation. This invention also provides a kit containing staining stock solution, basic reagents, and a parameter query unit. This invention transforms double-stained skeleton preparation from experience-dependent to data-driven, significantly improving repeatability and success rate, and is suitable for scientific research, teaching, and demonstration.

This invention relates to a method for preparing a jungle camouflage coating with a large near-infrared simulated water peak. Alizarin green intercalated hydrotalcite (ZnAl-LDHs-AG), bismuth vanadate (BiVO4), and SAR resin synthesized by co-precipitation are mixed in a mass ratio of 3:3:1 to obtain a composite green pigment. This pigment is then mixed uniformly with PVA adhesive and glycerol in a mass ratio of 1:1:1. Finally, the above solution is uniformly coated onto spandex fabric and dried at 160℃ for 10 min to obtain the jungle camouflage coating. The jungle camouflage coating prepared by this invention exhibits four major spectral characteristics: a green peak, a red edge, a plateau, and a water absorption peak, with a spectral similarity of 98.37% to that of green plants. This invention utilizes the synergistic water-locking system constructed by the introduction of SAR and glycerol, forming a stable hydrogen bond network that effectively locks in moisture in the coating, significantly enhancing the characteristic near-infrared water absorption peaks at 1400 nm and 1900 nm. The camouflage coating prepared by this invention is safe and environmentally friendly, has excellent weather resistance, and possesses thermal shielding properties comparable to natural green plants.

The invention provides chitosan for food packaging, a preparation method of the chitosan and a preparation method of a food packaging film, and belongs to the field of food engineering.The preparation method of the chitosan comprises the steps that natural pigment is added into N, N-dimethylformamide, stirring is conducted till the natural pigment is completely dissolved, and a pigment solution is obtained; dissolving chitosan in a glacial acetic acid aqueous solution, and fully swelling to form a transparent solution; dropwise adding the pigment solution into the transparent solution at room temperature, and uniformly stirring and mixing to obtain a mixture; adding a sufficient amount of a formaldehyde solution into the mixture until the reaction is completed, dropwise adding a sodium hydroxide solution to enable a product to form a precipitate, collecting the precipitate, and washing and freeze-drying the precipitate to obtain chitosan powder; wherein the natural pigment comprises curcumin and alizarin. The chitosan prepared by the method can improve the dispersibility of natural pigments in a film, improve the fixation mode of the pigments, avoid migration and loss, improve the light and heat stability of the natural pigments, improve the structural stability and mechanical properties of the film, and realize the double functions of preservation and indication.

This invention discloses alizarin / Al 3+ Application of alizarin / Al ratio fluorescent probe in ciprofloxacin detection 3+ The ratiometric fluorescent probe is composed of alizarin solution, AlCl3 solution, and HEPES buffer. In the presence of ciprofloxacin, upon excitation with light at a wavelength of 355-365 nm, it exhibits red fluorescence at 647-653 nm and blue fluorescence at 433-439 nm. Using red fluorescence as a reference signal and blue fluorescence as a response signal, the ratio of the two fluorescence signals shows a linear relationship with the concentration of ciprofloxacin, which can be used for the quantitative detection of ciprofloxacin. Furthermore, the alizarin / AlCl3 solution... 3+ The ratiometric fluorescent probe changes color from red through purple to blue as the concentration of ciprofloxacin increases, enabling semi-quantitative visual detection of ciprofloxacin. This alizarin / Al 3+ The base ratio fluorescent probe has excellent selectivity and anti-interference ability, which can realize the visual detection and quantitative analysis of ciprofloxacin residues in eggs with good sensitivity and high accuracy.

The application discloses a double-layer pH-sensitive fresh-cut fruit freshness indicating label and a preparation method and application thereof, and belongs to the technical field of fresh-cut fruit freshness monitoring. The preparation method takes a PLA and PEG blended film as a support substrate, takes a CS matrix loaded with alizarin and CEOE as a functional layer, and prepares a double-layer PSILs with a pH response function through a layer-by-layer casting method, and the double-layer PSILs is used in visual monitoring of fresh-cut fruit freshness. The application constructs a multi-layer composite film with a PLA-PEG composite film as a support layer material, the double-layer film exhibits optimal mechanical properties and relatively optimal water vapor barrier properties, and visual monitoring is realized in fresh-cut fruit freshness indication.

The invention relates to the technical field of biochemical medicine, in particular to a dry chemical qualitative detection method and a kit for detecting seminal plasma fructose. The method comprises the following steps: by adopting a room-temperature competitive color development system constructed by 3-quinoline boronic acid and alizarin red S, mixing a sample with a special diluent, and dropwise adding the mixture into the kit pre-loaded with test paper; and the judgment can be completed by comparing colors with naked eyes. The operation threshold and the cost limitation of equipment such as high performance liquid chromatography are avoided; the reaction is carried out under mild conditions, and strong corrosive reagents such as concentrated hydrochloric acid are not used, so that the operation safety is guaranteed; the sample treatment only needs simple dilution, and tedious pretreatment steps such as deproteinization, heating or derivatization are not needed, so that the detection efficiency is improved; the selected 3-quinoline boric acid, alizarin red S and auxiliary materials are conventional easily available chemical reagents, and the problem of obtaining special enzyme raw materials is solved. The technical effects of simplicity, convenience, quickness, safety, low cost and easiness in popularization are realized.

This invention belongs to the field of thin film processing technology, and relates to a colorimetric membrane, its preparation method, and its application. The colorimetric membrane prepared according to this invention comprises, by mass parts, 2.3-2.7 parts sodium alginate, 1.1-1.4 parts rice protein powder, 1.1-1.4 parts gelatin, 1.1-1.4 parts glycerol, 0.2-0.3 parts polydimethylsiloxane, and 0.15-0.25 parts anthocyanins; it may also include alizarin and phenolic acids. The colorimetric membrane of this invention has a wide pH response color gamut and color intensity, and good mechanical properties. The total color difference of the colorimetric membrane of this invention can reach up to 54.19, making the response of the colorimetric membrane material to the alkaline environment during food spoilage more intuitive and discernible. This invention uses specific types of phenolic acids, which significantly improves color stability while maintaining the wide color gamut response of the composite membrane; this stability and enhanced color development provide a guarantee for the long-term reliable application of intelligent packaging in the circulation and storage stages.

The present application belongs to the technical field of borax detection, and particularly relates to a method for improving the detection sensitivity of borax in toys. In the process of detecting the borax content in toys by using alizarin S solution, diphenylcarbazone solution is added as a color developer. By observing the color of the solution after the reaction, it can be quickly screened whether the borax in the toy clay exceeds the limit value of 3750 mg / kg, whether the borax in the crystal mud gel exceeds the limit value of 1250 mg / kg, and the toy products with excessive borax content are screened out. The detection of the borax content in the crystal mud and the toy clay is realized, and the quantitative limits of 0, 1250 and 3750 mg / kg are achieved. The method of the present application can be used for on-site rapid detection, and the operation is simple, which provides convenience for on-site rapid screening and quantification of the borax content.

The invention discloses a preparation method of a co-immobilized laccase-mediator system, which comprises the following steps: mixing and oscillating a laccase solution and a 2-methylimidazole solution, adding a manganese chloride solution, oscillating and uniformly mixing, reacting the obtained mixed solution in a shaking table for a preset time, sequentially adding p-coumaric acid and 2, 4-dihydroxy-2-methylimidazole, reacting for a preset period of time, filtering, washing, and drying to obtain the co-immobilized laccase-mediator system. The preparation method comprises the following steps: adding a laccase-mediator system MnMOF (at) Lac5 (at) M (at) PEG (Polyethylene Glycol) into a reaction kettle, carrying out oscillation reaction on the laccase-mediator system MnMOF (at) Lac5 (at) M (at) PEG and 2, 2-nitrogen-bis (3-ethyl-benzothiazole-6-sulfonic acid) diammonium salt ABTS for 3-5 hours, then adding polyethylene glycol PEG, centrifuging and washing to obtain the co-immobilized laccase-mediator system MnMOF Compared with free enzyme, the PEG modified laccase-mediator co-immobilization system adopted by the invention has the advantages that the enzyme activity is improved by more than two times, and excellent reusability is shown; under the condition of 30 DEG C, the immobilized laccase-mediator system can realize 100% degradation of alizarin red within 15 minutes, and a green and efficient treatment technology is provided for dye degradation; meanwhile, the system has a good application prospect in the fields of sewage treatment, bioremediation and the like.

The invention belongs to the field of packaging materials, and provides a dual-indication intelligent fresh-keeping label film as well as a preparation method and application thereof. The double-indication intelligent fresh-keeping label film comprises an antibacterial fluorescence monitoring layer and a colorimetric response layer which are sequentially stacked in the thickness direction; the antibacterial fluorescent monitoring layer comprises a first base material layer as well as antibacterial nanoparticles and fluorescent nanoparticles which are combined on the first base material layer, and the antibacterial nanoparticles comprise cinnamyl aldehyde and beta-cyclodextrin coating the cinnamyl aldehyde; the fluorescent nanoparticles are supramolecular assemblies which are synthesized by associating and inducing sulfobutyl beta-cyclodextrin and berberine; the colorimetric response layer comprises a second base material layer and alizarin loaded on the second base material layer. The double-indication intelligent fresh-keeping label film provided by the invention integrates visual monitoring and antibacterial and fresh-keeping functions, and can be widely applied to the field of food packaging or meat freshness indication.

The application discloses a hydrogel for improving the precision of photocuring 3D printing and application thereof. The application finds that the precision of photocuring 3D printing can be improved by adding a pigment such as thioflavin T, alizarin yellow R, methylene blue and / or purple cabbage into an ink containing a photo-crosslinking hydrogel such as methacrylated gelatin (GelMA) as a photocuring stabilizer. Based on this, the application provides a hydrogel ink capable of improving the precision of photocuring 3D printing, and by mixing the photo-crosslinking hydrogel with a photo initiator and a photocuring stabilizer in proportion, the entity obtained by printing using the hydrogel ink has higher precision. In addition, the operation of 3D printing using the hydrogel ink is simple, has strong practicability, and is beneficial to the construction of repair materials required in the biomedical field such as tissue engineering.