Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
210results about How to "Achieving High Sensitivity Detection" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Time resolution fluorescence spectral measuring and image forming method and its device
InactiveCN1912587ADifferent temporal resolutionsAchieving high-sensitivity detectionFluorescence/phosphorescencePhotocathodePicosecond
A method of using picosecond scan camera to simultaneously obtain fluorescent light spectrum and fluorescent lifetime of sample includes focusing blue violet light emitted by laser on sample by objective to excite sample single photon, collecting fluorescent from sample then splitting it and focusing it to be image on photoelectric cathode of picosecond scan camera, setting dispersion direction of fluorescent to be the same as slit direction of said camera but to be vertical to scan direction in order to measure out fluorescent lifetime of different light spectrum simultaneously under coaction of scan circuit and image intensifier deflection system.
Owner:SHENZHEN UNIV
Five-dimensional fluorescent microscope imaging technique
InactiveCN1737536AMeasurable fluorescence lifetimeImprove spatial resolutionColor/spectral properties measurementsFluorescence/phosphorescenceMicroscopic imageFluorescence
This invention relates to one method to acquire biology spectrum information and life information and to realize three-dimensional imaging. The invention is characterized by the following: getting multi-photon or single photon triggering of five-dimensional fluorescent microscope imaging information, that is three-dimensional space, one dimensional time and spectrum. This multi-parameter compound measurement and technique, which can satisfy the needs of different layers in study and can realize the flexible made three-dimensional spectrum for measurement.
Owner:SHENZHEN UNIV
Graphene/carbon nanotube network flexible multifunctional strain sensor preparation method
ActiveCN106767374APractical application value is greatImprove tensile propertiesElectrical/magnetic solid deformation measurementCarbon nanotubeMicroheater
The invention discloses a three-dimensional graphene / carbon nanotube network flexible multifunctional strain sensor preparation method. According to the invention, the three-dimensional network of three-dimensional graphene and a one-dimensional carbon nanotube grows through two-step chemical vapor deposition; and the three-dimensional network and an elastic polymer as a flexible substrate are solidified and combined to acquire a flexible wearable multifunctional electronic strain sensor based on the three-dimensional network of the graphene and the carbon nanotube. According to the invention, the electronic strain sensor breaks the limitation relationship between the strainability and the sensitivity of the strain sensor, has an excellent electronic strain sensing performance and the function of a micro heater, realizes high sensitivity detection of human physiological signals and physical activities, shows excellent electronic skin simulation capabilities and a micro heating source application performance, has the advantage of simple process, and can be widely used in many fields such as clinical diagnosis, health monitoring, a robot, an electronic screen, electronic skin, a flexible micro heater and intelligent home.
Owner:NANJING UNIV OF TECH
Silver-poly dopamine-graphene-modified electrochemical sensor and preparation method thereof
InactiveCN102914580AHigh sensitivityImprove conductivityMaterial electrochemical variablesGraphiteElectrochemistry
The invention discloses a silver-poly dopamine-graphene-composite-modified electrochemical sensor which is mainly characterized in that a silver-poly dopamine-graphene composite membrane is coated on the surface of a glassy carbon electrode. A preparation method of the silver-poly dopamine-graphene-composite-modified electrochemical sensor includes: adding silver-poly dopamine-graphene into dimethylformamide for uniform dispersing so that silver-poly dopamine-graphene dispersion liquid is obtained, then coating the dispersion liquid on the surface of the glassy carbon electrode, and evaporating solvent to obtain the needed sensor. A silver-poly dopamine-graphene composite is prepared only by mixing reactants and stirring at the room temperature. The preparation method is simple, mild in reaction conditions and low in cost. The prepared electrochemical sensor has the advantages of high sensitivity, low detection limit and the like, and is capable of achieving rapid sensitivity determination of guanine and adenine, simple to operate, green and environment-friendly.
Owner:XINYANG NORMAL UNIVERSITY
Small ultraviolet frequency sweeping laser-based resonance Raman spectrum detection system and method
ActiveCN104849257AMiniaturizationAchieving high-sensitivity detectionRadiation pyrometryRaman scatteringRaman lineUltraviolet
The invention discloses a small ultraviolet frequency sweeping laser-based resonance Raman spectrum detection system method. The small ultraviolet frequency sweeping laser based resonance Raman spectrum detection system comprises a small ultraviolet frequency sweeping laser, a main controller and a data analysis system, wherein the small ultraviolet frequency sweeping laser is composed of a pulse semiconductor laser assembly, an optical fiber laser assembly and an ultraviolet frequency sweeping optical assembly; the testing point of a detected object is located in a molecular composition of a material, has the intensity of a stokes Raman line of molecules with the ultraviolet frequency sweeping wavelength corresponding to the resonance Raman excitation wavelength is enhanced by tens of thousands to millions of times, and thus, multiple molecules of a sample, having extremely low concentration, can be detected. The system has the beneficial effects that an electronic-optical fiber integrated structure is adopted, so that an ultraviolet frequency sweeping laser source is miniaturized; an acousto-optic tunable filter is adopted, and thus, the ultraviolet laser frequency can be rapidly adjusted; and according to the ultraviolet frequency sweeping resonance Raman method, fluorescence interference is eliminated, the high-sensitivity resonance Raman detection of the multiple molecules of the sample can be achieved through fast frequency sweeping.
Owner:SHANGHAI INST OF TECHNICAL PHYSICS - CHINESE ACAD OF SCI
Method for manufacturing alternating current electrophoresis directionally assembled carbon nanotube array sensing device
InactiveCN101788516AHigh sensitivityHigh selectivityElectrophoretic coatingsMaterial resistanceMetallic electrodeElectrophoresis
The invention discloses a method for preparing an alternating current electrophoresis directionally assembled carbon nanotube array sensing device, which is characterized by comprising the following steps: making a diagram of an alternating-current electrophoresis metal electrode by using a photoetching method or a metal deposition method; growing a graphene film on the alternating-current electrophoresis metal electrode; applying alternating-current electrophoresis to ultrasonically dispersed carbon nanotubes by using the graphene-covered metal electrodes to perform directional assembly to form a carbon nanotube array; removing or oxidating metal tubes in the carbon nanotube array by using an overload current burning method or an ultraviolet lighting method, or simultaneously removing the metal tubes in the carbon nanotube array by combining the two methods; and modifying the directional carbon nanotube array with metal nanometer particles or polymers. The method uses the graphene-covered metal electrode as the alternating-current electrophoresis electrode to prepare a high-performance directional high-intensity carbon nanotube array field effect device, improves the sensitivity and the detection selectivity of the device, and can realize the high-sensitivity portable detection of gas which pollutes the environment.
Owner:SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
Surface enhanced Raman scattering substrate, preparation method therefor and application thereof
ActiveCN103526291AEasy to controlHigh Surface Enhanced Raman EffectPolycrystalline material growthLiquid-phase epitaxial-layer growthCooking & bakingWater baths
The invention discloses a ZnO-Ag surface enhanced Raman scattering substrate and detection of organic pollutants with the substrate. The preparation method for the substrate comprises the following steps: the first step, ITO conductive glass is subjected to ultrasonic cleaning with acetone, alcohol and deionized water one by one and dried in the air; the second step, organic additives are added in a zinc nitrate solution, a first mixed liquid is formed, after the first mixed liquid is stirred for 30 min, an ammonia-water solution with a mass fraction of 25% is dropwisely added in the first mixed liquid, a second mixed liquid is formed, the processed ITO conductive glass from the first step is soaked in the second mixed liquid, after the water bath is at a constant temperature, the ITO conductive glass is placed in a baking box and baked for 60-100 min, a white and uniform ZnO layer is formed on the surface of the ITO conductive glass; the third step, Ag nanoparticles are deposited on the prepared ZnO nanolayer from the second step, and a ZnO-Ag surface enhanced Raman scattering substrate is obtained. The preparation method is simple. The prepared substrate has high sensitivity and good stability and can be used repeatedly.
Owner:INST OF CHEM MATERIAL CHINA ACADEMY OF ENG PHYSICS
Metal oxide-metal-organic frameworks (MOX@MOFs) nanometer core-shell structure one-dimensional array as well as preparation method and application thereof
ActiveCN105510395AHigh Sensitivity DetectionEasy to promoteMaterial resistanceOperating temperatureMicrometer
The invention provides an MOX@MOFs (metal oxide-metal-organic frameworks) nanometer core-shell structure one-dimensional array film which is characterized in that the film thickness is 2 to 4 micrometers, and the film is formed by a one-dimensional MOX@MOFs core-shell structure, wherein the diameter of a core MOX nanowire is 50 to 100nm, the thickness of a shell MOFs can be adjusted between 1nm to 200nm, metal nodes and organic chains of the MOFs can be adjusted. A typical preparation method comprises the steps of setting an MOX face of a ZnO one-dimensional array film downwards, adding into a mixed solution of water in which zinc salt, cobalt salt and organic ligands are dissolved and DMF, sealing a reaction still, then heating for reacting, after reacting, washing the surface of a compound array film, and drying the film in the air. The MOX@MOFs core-shell structure one-dimensional array film provided by the invention has excellent gas-sensitive property, not only can humidity interference be selectively eliminated, but also the working temperature can be reduced and the sensitivity can be improved through a Co catalysis. Meanwhile, the film also has the advantages that the method is simple, and the cost is low.
Owner:FUJIAN INST OF RES ON THE STRUCTURE OF MATTER CHINESE ACAD OF SCI
Photoelectrochemical sensor, and preparation and application thereof
ActiveCN106501336APhotoresponse dropHigh photocurrent responseMaterial analysis by electric/magnetic meansElectron injectionEngineering
The invention relates to a photoelectrochemical sensor, and preparation and application thereof. A preparation method for the photoelectrochemical sensor comprises the following steps: S1, pretreating ITO electro-conductive glass; S2, adding TiO2 nanoparticles onto the ITO electro-conductive glass drop by drop to prepare an ITO / TiO2 electrode; S3, soaking the electrode in a carbon quantum dot solution for 10 h so as to obtain an ITO / TiO2 / CODs electrode; S4, adding chitosan onto the electrode drop by drop so as to obtain an ITO / TiO2 / CODs / CS electrode; S5, adding a glutaraldehyde solution onto the electrode drop by drop; and S6, dropwise adding thrombin aptamer drops, carrying out a reaction at 4 DEG C under a wet condition for 10 to 15 h, continuing adding bovine serum albumin onto the electrode drop by drop after leaching and blow-drying, and carrying out leaching and blow-drying again. The prepared photoelectrochemical sensor can be used for detection of thrombin. According to the invention, the carbon quantum dots with a wide visible light absorption range, good luminosity and high-efficiency electron injection capability are used as a photosensitizer for titanium dioxide, so the obtained composite structure has good response to photoelectric current under visible light. The prepared photoelectrochemical sensor has the advantages of simple operation, low cost, environment friendliness, high sensitivity and good selectivity.
Owner:SHANTOU UNIV
Zirconium-base metal organic frame composite material and preparing method and application thereof
ActiveCN109651621AAchieving High Sensitivity DetectionGood dispersionChemiluminescene/bioluminescenceMaterial electrochemical variablesElectricitySignalling molecules
The invention discloses a zirconium-base metal organic frame composite material and a preparing method and application thereof. By controlling experiment conditions, a UiO-66-NH2 metal organic frame material with the grain diameter of 100 nm is obtained, and serves as a loading matrix, a signal molecule tri-(2,2'-dipyridyl) ruthenium dichloride is embedded in a pore way structure regularly and evenly distributed, a Ru-UiO-66-NH2 material is obtained, loading of silver nanoparticles is conducted through the high specific surface area of the Ru-UiO-66-NH2 material, and the obtained Ru-UiO-66-NH2material is applied to detection of small-molecule hydrogen peroxide with the electrogenerated chemiluminescence detection technology. Through the method, interference of background signals can be avoided, optical signals are stable, and the sensitivity is high.
Owner:ANHUI NORMAL UNIV
Preparation method of hollow Ag-Au alloy complex structure micro-nano array
ActiveCN108277484AEasy to prepareEasy to operateMaterial nanotechnologyRaman scatteringCompound structureMelamine
The invention discloses a preparation method of a hollow Ag-Au alloy complex structure micro-nano array. A silver bowl array prepared on the basis of a PS monolayer crystal colloid temperature and theelectro-deposition technology serves as a secondary template; a bowl hole type array composed of Ag-Au alloy nano-particles is obtained through the chloroauric acid corrosion process, and high-sensitivity detection of 10-9M melamine is achieved. Through electric field distribution of a FDTD software simulating calaculation structure, the simulation result is basically matched with the experimental result. As a result, an Ag-Au BPAN array at the proper Ag-Au ratio has good SERS properties indeed, and the sensitivity and the peak response intensity of the hollow Ag-Au alloy complex structure micro-nano array are much better than those of an existing structure.
Owner:ANHUI NORMAL UNIV
Application of diamond-like carbon film used as matrix in laser desorption ionization mass spectra
InactiveCN101846650AEasy to analyzeEliminate background distractionsMaterial analysis by electric/magnetic meansNatural productDiamond-like carbon
The invention relates to a laser desorption ionization mass spectra, in particular to application of diamond-like carbon film used as matrix in the laser desorption ionization mass spectra; the surface of the diamond-like carbon film is used as an assisting matrix of laser desorption ionization flying time mass spectra, the diamond-like carbon film has high desorption ionization efficiency to compounds with low molecular weight and can not generate background interference of matrix molecules, so as to realize high-efficiency and rapid detection to the compounds with low molecular weight; the laser desorption ionization flying time mass spectra which adopts the diamond-like carbon film as the assisting matrix is a new desorption ionization method without adding any organic matrix, so as toprovide a general, high-efficiency and rapid detection method for the compounds with low molecular weight such as natural products and ecological metabolites, promote the development of analysis of compounds with low molecular weight by the laser desorption ionization flying time mass spectra technology and find new field for the application of the diamond-like carbon film material.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
Method for rapid detection of residual amount of sulfanilamide in food
ActiveCN103760141AAchieving High Sensitivity DetectionReduce distractionsFluorescence/phosphorescenceFluorescamineSulfanilamide
The invention discloses a method for rapid detection of the residual mount of sulfanilamide in food. The method comprises the following steps: firstly enabling the sulfanilamide and fluorescamine to perform derivation reaction, further enriching derivative products by using cloud point extraction, adding a sample enrichment and a standard plate prepared from a sulfanilamide standard product on a thin layer silica gel plate, comparing the fluorescence intensities of the two under an ultraviolet lamp to judge the concentration range of the fluorescamine in a sample, and determining the residual amount of the sulfanilamide in the food, wherein a detection limit of the method is 0.08 micron g / mL. The method disclosed by the invention has the advantages of simplicity in operation, small using amount of organic solvent, high detection sensitivity, short detection time, strong specificity and capability of realizing effective separation from interfering substances, is a simple, convenient, fast and accurate analytical method, does not need large-scale instruments, only needs to configure small-scale instruments and equipment, and further has extensive application prospects.
Owner:KUNMING UNIV OF SCI & TECH
Biosensor for detecting streptomycin based on aptamer and preparation method of biosensor
ActiveCN104764790AHighly specific detectionAchieve recyclingMaterial electrochemical variablesAptamerQuantitative determination
The invention provides a biosensor for detecting streptomycin based on an aptamer. The biosensor comprises a gold electrode, wherein an MB capture probe layer, HAP and an ssDNA layer are sequentially modified on the gold electrode. The invention also provides a preparation method of the biosensor. Based on specific recognition of the aptamer and the target, the sensor has the advantages of high detection speed, low detection limit, high specificity and the like, the defects of the conventional streptomycin detection method can be overcome, and rapid and accurate quantitative determination is realized.
Owner:UNIV OF JINAN
Deoxyribonucleic acid (DNA) fragment amplification and quantitative detection system based on closed reactors
ActiveCN102618439AAvoid Potential Contamination RisksAchieve absorptionBioreactor/fermenter combinationsBiological substance pretreatmentsFluorescenceDNA fragmentation
The invention relates to a deoxyribonucleic acid (DNA) fragment amplification and quantitative detection system based on closed reactors, belonging to the technical field of molecular biology detection systems. The DNA fragment amplification and quantitative detection system comprises an amplification unit. A group of closed reactors are arranged in the amplification unit in a matching way. An exciting light device and a fluorescence detection device are arranged on one side of each closed reactor in a matching way. A transmission device which is used for providing power to the closed reactors is arranged at the bottom of the amplification unit in a matching way. The transmission device is connected with a motor. Two or more than two independent constant-temperature areas at different temperatures are arranged in the amplification unit in a matching way. By adopting the technique, the thermal response of reagent samples is improved, the polymerase chain reaction process is accelerated and the experimental period is greatly shortened; the degradation of DNA enzymes is reduced, the amplification sensitivity, accuracy and reproducibility of the samples are improved and the reagent detection linearity range is expanded; the pollution risk during experiments is reduced; the optical path is shortened and the sensitivity and the low background of optical detection are improved; and the low-cost multi-sample multi-channel detection is realized.
Owner:胡惠平
Method for detecting amoxicillin residual quantity in milk and meat product
InactiveCN102072892AAchieving High Sensitivity DetectionDirect measurement has low sensitivityColor/spectral properties measurementsFluorescence/phosphorescenceQuinoneUltraviolet
The invention discloses a method for detecting amoxicillin residual quantity in milk and meat products. The method includes the following steps: preparing amoxicillin standard aqueous solution; adding a nonionic surfactant; reacting the obtained solution with quinone or alizarin to get a charge transfer system; determining the wavelength scanning range of fluorescence or ultraviolet; further calculating the linear range, working curve and other parameters of the standard solution; processing the sample to be detected by corresponding charge transfer reaction; determining reaction parameters under ultraviolet or fluorescence; and calculating to obtain the amoxicillin residue quantity. The technology further enhances the value of fluorescence intensity or UV absorption by utilizing the sensitizing effect of non-ionic surfactants, thus meets the low-residue testing requirement; simultaneously improves the system stability significantly, makes up the disadvantage of poor detection stability of fluorescence in the earlier application, and is more feasible in the actual detection.
Owner:云南健牛环境监测有限公司
Thrombin detection method based on splitter adapter and water-soluble conjugated polymer
ActiveCN103630517ARealize detectionEasy to detectFluorescence/phosphorescenceEffective energySoluble polymer
The invention discloses a thrombin detection method based on a splitter adapter and a water-soluble conjugated polymer. According to the method, a super-molecular detection platform based on a water-soluble conjugated polymer / nucleic acid adapter is designed by virtue of the sensitivity of the water-soluble polymer on a comformational change of a deoxyribonucleic acid (DNA) chain and according to the characteristics that the nucleic acid adapter has specific binding ability and the like. Two sequences cannot form a G-four-chain structure when thrombin does not exist in a solution or other nonspecific proteins exist in the solution, the distance from a compound to the polymer is small, and thus effective energy transfer between the compound and the polymer can be realized; when the thrombin exists in the solution, the thrombin induces the two sequences to form the G-four-chain structure, and the distance between the compound and the polymer is increased, so that effective energy transfer cannot be carried out. The method disclosed by the invention is simple, convenient and fast, is high in sensitivity and selectivity, and has important significance in the aspect of thrombin detection.
Owner:深圳云安智慧医疗科技有限公司
Construction method and application of electrochemical Faraday cage immunosensor for detecting activity of histone acetyltransferase
ActiveCN108593751AHigh sensitivityAchieving High Sensitivity DetectionMaterial electrochemical variablesWater bathsUltrasonic dispersion
The invention discloses a construction method and an application of an electrochemical Faraday cage immunosensor for detecting the activity of histone acetyltransferase. The construction method comprises the following steps: (1) preparing peptide / Au: respectively taking acetyltransferase p300, polypeptide and acetyl-CoA, fully mixing the taken substances in PBS (0.1 M, pH 7.0), incubating the obtained solution in a constant-temperature water bath, taking and dropwise applying a catalytic reaction to the surface of a gold electrode, and incubating the gold electrode in a 4 DEG C refrigerator; (2) preparing MB&AuNPs@GO-Ab: mixing HAuCl4 and CTAB with water, adding ascorbic acid to the obtained reaction mixture, adding NaOH to obtain CTAB covered AuNPs, centrifuging and purifying the CTAB covered AuNPs, dispersing the purified CTAB covered AuNPs in an equal amount of water, adding GO to the obtained solution, performing ultrasonic dispersion, standing the dispersed solution for later use,adding an acetyl antibody, performing incubation, adding MB, and performing vibration and uniform mixing; and (3) producing the electrochemical Faraday cage immunosensor: taking and dropwise applyingthe MB&AuNPs@GO-Ab to the surface of the peptide / Au, performing incubation at room temperature, and placing the produced sensor in the PBS (0.1 M, pH 7.0) to carry out electrochemical SWV test.
Owner:NINGBO UNIV
A water-dispersible fluorescent polymer nanoparticle with pH value and mercury ion ratio detection function, preparation method and application
InactiveCN104151480BThe synthesis method is simpleEasy to retouchFluorescence/phosphorescenceLuminescent compositionsAminoethyl methacrylateWater dispersible
Owner:HUNAN UNIV OF SCI & TECH
Photovoltaic near and middle infrared double-color detector for Si-based three-dimensional Ge quantum dot crystal
InactiveCN106847952AImprove performanceAchieving high-sensitivity detectionPhotovoltaic energy generationSemiconductor devicesMiddle infraredValence band
The invention relates to a photovoltaic near-infrared and middle-infrared double-color detector for an Si-based three-dimensional Ge quantum dot crystal. The detector structure is a photovoltaic light-emitting diode structure of a PIN or NIP structure, wherein the three-dimensional Ge quantum dot crystal serves as a light absorption region. Strong near-infrared and middle-infrared band light absorption is formed by using efficient ground state micro-strip interband transition and valence band micro-strip sub-band interband transition inside the three-dimensional Ge quantum dot crystal, so that efficient double-color detection for near-infrared and middle-infrared wave bands is realized simultaneously, and the photovoltaic near and middle infrared double-color detector has wide application prospect in the technical field of infrared sensing.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI
Boron-doped carbon-base fluorescent nano material, and preparation method and application thereof
InactiveCN106675555AHigh sensitivityHigh selectivityFluorescence/phosphorescenceLuminescent compositionsDevice materialBoron doped carbon
The invention discloses a boron-doped carbon-base fluorescent nano material, and a preparation method and application thereof. The surface B atom content of the nano material is 11.61%; and a hydrothermal process is utilized to prepare the boron-doped carbon-base (B-Cdots) fluorescent nano material which is used for detecting lead ions and copper ions. The simple hydrothermal synthesis process is adopted to synthesize the high-B-content B-Cdots fluorescent nano material, thereby effectively enhancing the B atom doping content, being beneficial to widening the application range of the carbon-base fluorescent material in environmental detection, solving the technical problem of demands for harsh experimental conditions by the synthesis of the B-doped nano material, and implementing the high-selectivity detection on heavy metal ions. The fluorescent experiment test indicates that the B-Cdots fluorescent nano material has favorable specific effects on Pb<2+> and Cu<2+>, and can implement high-sensitivity detection on the Pb<2+> and Cu<2+>. The product not only can be used for detecting heavy metal ions, but also can be used as a fluorescent probe for other fluorescent sensors and in the fields of pollutant treatment, preparation of fluorescent device materials and composite nano materials, and the like.
Owner:YANCHENG INST OF TECH
Ultrasonic phased array detection system for transitional circular arc inside cavity
ActiveCN102706960AAchieving High Sensitivity DetectionGuaranteed uptimeAnalysing solids using sonic/ultrasonic/infrasonic wavesUltrasoundInstrumentation
The invention relates to an ultrasonic phased array detection system for a transitional circular arc inside a cavity. The system comprises an ultrasonic phased array detector, a detection probe and a positioning device. The system is characterized in that a probe propelling device consisting of an auxiliary operating frame, a balancing weight, a probe clamping block, a fine steel wire and the like is designed. The ultrasonic phased array detection system for the transitional circular arc inside the cavity provided by the invention has the advantages of: 1, ensuring that the centre of curvature of an arc-shaped wafer of the detection probe is concentric with the circular arc detected so that an ultrasonic wave is vertically incident to corner parts of the circular arc detected so as to realize detection with high sensitivity of all parts of the circular arc; 2, ensuring that the probe operates stably in the cavity structure clings to the side wall of the circular arc detected; 3, ensuring coupling of detection by forming a sealed water cavity between the detection wafer of the probe and the circular arc detected through the detection probe and the front and back clamping blocks; and 4, precisely positioning the movement position of the detection probe through the probe positioning device so as to position the defect horizontal position precisely.
Owner:AVIC BEIJING INST OF AERONAUTICAL MATERIALS
Rapid protein analysis and detection device based on whole microfluidic chip closing system
The invention relates to a micro device for performing on-line enrichment, elution, fluorescence labeling and detection on protein, and in particular provides a rapid protein analysis and detection device based on whole microfluidic chip closing system. The device is composed of a micro fluidic controlling system, a miniature laser induced fluorescence detection system, a microfluidic chip, an injection valve, a connecting pipeline, an interface and a data acquisition and processing part. A protein sample is enriched by an enriching column in a chip passage, is subjected to on-line fluorescence labeling operation and elution operation at the same time, and is induced by laser to be subjected to fluorescence detection. The rapid protein analysis and detection device has the advantages that the sample pre-processing process, fluorescence labeling and detection are integrated so as to enable cumbersome steps of an off-line analysis method to be omitted, the sample processing time is greatly shortened and the high sensitivity detection is achieved; the whole device is small in size and low in energy consumption; the microfluidic chip and a micro injection pump are connected through the interface with a special design; a whole fluid system runs in the closing system, the detection requirement under a special condition (such as non-gravity state) can be met. Thereby, the rapid protein analysis and detection device has the very good practical application value.
Owner:DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
One step amplification method of fluorescence detection for mercury ions
InactiveCN105044067AHighly specific detectionAchieve recyclingFluorescence/phosphorescenceAptamerSpecific detection
The invention provides a one step amplification method of fluorescence detection for mercury ions. Detection for the mercury ions is realized on the basis of a principle that the mercury ions can stabilize T-T mismatch in DNA (deoxyribonucleic acid), the specific recognition of a nucleic acid aptamer is used, aptamers of the mercury ions serve as recognition substances to realize the high specific detection for the target mercury ions, reaction speed is improved by using a fluorescence detection method, complexity of the operation is lowered, and fast, simple and flexible detection for the target is realized.
Owner:UNIV OF JINAN
Molecular imprinting microfluidics sensor based on double-annular-fiber-core optical fiber and double-annular-fiber-core optical fiber
InactiveCN103900993ASimple structureReduce volumeOptical fibre with multilayer core/claddingPhase-affecting property measurementsFiberMicrofluidics
The invention provides a molecular imprinting microfluidics sensor based on a double-annular-fiber-core optical fiber and the double-annular-fiber-core optical fiber. The double-annular-fiber-core optical fiber comprises two annular fiber cores and a microfluid channel [4], wherein the first annular fiber core [1] is positioned on the inner wall of an annular wrapping layer [2]; the second fiber core [3] is positioned inside the annular wrapping layer [2]; the microfluid channel [4] is used as a sample sensing field; a molecular imprinting sensitive layer [8] is arranged on the inner surface of the annular fiber core [1]; micro holes [6] and [7] are formed in the surface of the double-annular-fiber-core optical fiber; two micro holes are positioned in one same side of the double-annular-fiber-core optical fiber; the double-annular-fiber-core optical fiber [5] is connected with an incident optical fiber [11] and an emergent optical fiber [12] through optical fiber pull conical points [9] and [10]; the incident optical fiber [11] is connected with an optical fiber coupler [16]; the optical fiber coupler [16] is connected with a light source [17]; the emergent optical fiber [12] is connected with a spectrometer [18]. The sensor is simple in structure and small in size, and can achieve high-selectivity on-line microfluidics detection.
Owner:HARBIN ENG UNIV
Dialysis device and silicon nanowire field-effect tube combined biosensor
The invention relates to a dialysis device and silicon nanowire field-effect tube combined biosensor. The dialysis device and silicon nanowire field-effect tube combined biosensor comprises a dialysisdevice, a silicon nanowire field-effect tube and a signal output computer, wherein the dialysis device is communicated with the silicon nanowire field-effect tube through a thin silica gel flexible pipe; and the silicon nanowire field-effect tube transmits a signal to the signal output computer through a probe. The serum desalting dialysis device and the silicon nanowire field-effect tube are connected into the same pipeline; the dialysis device is used as a filter; the field-effect tube having a double gate structure with a semiconductor silicon nanowire as a channel is used as a signal converter; an antibody corresponding to a tumor marker is used as a biological sensitive element; and therefore, the immediate, label-free and high-sensitivity detection of the serum tumor marker is realized.
Owner:WUXI PEOPLES HOSPITAL
Electrochemical sensor for detecting ATP and preparation method thereof
ActiveCN109596685ALow detection limitAchieve recyclingMaterial electrochemical variablesAptamerSignal amplification
The invention relates to the technical field of the biosensor, and especially relates to a biosensor for detecting ATP by bringing Apt-1 and Apt-2 closer by ATP and using branch HCR amplification signal. A CP-SH layer, an AP layer, a HP1-HP2-HP3-HP4 layer and a [Ru(NH3)6]3+ layer are orderly modified on an electrode; the preparation method comprises the following steps: pre-treating the electrode,modifying the CP-SH layer to an electrode surface; modifying the AP layer to the electrode surface, and modifying the HP1-HP2-HP3-HP4 layer to the electrode surface, and modifying the[Ru(NH3)6]3+ layer to the electrode surface. The high specificity detection of the target object ATP is realized by utilizing the specificity identification of the aptamer; by utilizing the effect of bring two aptamers closer by the ATP, the cyclic utilization of the target object is realized, and the effect of the first-step signal amplification is achieved. And a signal continuous enhancement effect is realizedby utilizing branch HCR.
Owner:UNIV OF JINAN
Wavelength modulation absorption spectrum absorption optical path and gas concentration synchronous inversion method
PendingCN111351770AHigh Sensitivity Absorption Pathlength and Gas Concentration DetectionAchieving high-sensitivity detectionColor/spectral properties measurementsOptical pathOptical pathlength
The invention relates to a wavelength modulation absorption spectrum absorption optical path and gas concentration synchronous inversion method. The method comprises the following steps: (1) acquiringan absorption signal It and a background signal It, 0; (2) obtaining a first harmonic phase baseline value and a first harmonic phase angle differential signal delta theta 1f-0 of which background signals are deducted by adopting a quadrature demodulation method; (3) solving an absorption optical path Labs by adopting a formula; and (4) performing least square method linear fitting on the differential phase angle delta theta 1f-0 of which the background is deducted by adopting the following formula so as to obtain the concentration of to-be-detected gas, according to the present invention, with the method, the defects in the prior art can be overcome, the absorption optical path and the gas concentration can be rapidly and synchronously inverted, the high-sensitivity absorption optical path and the gas concentration detection can be achieved, and the method is especially suitable for the gas detection environment with the obvious noise such as remote measurement and the like.
Owner:HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
Terahertz metamaterial chip for cell invasion and migration unmarked detection
PendingCN109456889ASimple structureEasy to assembleBioreactor/fermenter combinationsBiological substance pretreatmentsCell invasionTerahertz metamaterials
The invention relates to a terahertz metamaterial chip for cell invasion and migration unmarked detection. A cell culture chamber, a porous film and a metamaterial chip layer are integrated, and by alocally enhanced electric field of the terahertz metamaterial in vertical micron distribution, in-situ unmarked detection of quantity of cells penetrating the porous film is performed to assess movement behaviors such as cell invasion and migration. A whole device is simple in structure, convenient to assemble, small in size, easy to integrate and reusable.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV
Method for detecting trace iron ions at high sensitivity
InactiveCN101788492AAchieving high sensitivity detectionStrong and stable fluorescent propertiesChemiluminescene/bioluminescenceRelative standard deviationLinearity
The invention discloses a method for detecting trace iron ions at high sensitivity, which comprises the steps of: searching a proper medium condition of diaminomaleonitrile (DAMN); measuring fluorescence intensities of a coordination compound, the coordination compound and a medium, and the coordination compound and the medium and metal ions; determining hypersensitivity or quenching effect generated by metal ions to the fluorescence of the coordination compound; measuring a linear relation between the concentration of the metal ions and a quenching value; and measuring the content of the metal ions in food. By using characteristic of quenching generated by the iron ions to the fluorescence of the DAMN and the linear relation formed between the fluorescence quenching value (delta F) and the concentration of the iron ions, the method is further used for measuring the content of iron in foods of infant rice flour, milk powder and the like, wherein the detection limit of the iron is 1.5 mu g.L<-1>, and the relative standard deviation is 0.17 percent. Compared with the prior art, the method has the advantages of good selectivity, high sensitivity, simple and convenient use, and the like.
Owner:YANCHENG TEACHERS UNIV
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com