3results about How to "Achieving High Sensitivity Detection" patented technology

The application discloses a self-powered micro hair-like sensor, which comprises a hair structure, a mechanical structure layer and a substrate; the hair structure is bonded with the mechanical structure layer through a micro assembly process; the mechanical structure layer is provided with a moving platform, a constraint unit and a bridge amplification unit obtained through an etching process; the mechanical structure layer is bonded with the substrate as one of friction layers; the substrate is another friction layer; the moving platform is connected to the root of the hair structure; the moving platform is in a rectangular shape, one set of opposite sides of the rectangular shape are connected with corresponding constraint units respectively, and the other set of opposite sides are connected with corresponding bridge amplification units respectively; and the two bridge amplification units are connected through the corresponding constraint units. The self-powered micro hair-like sensor realizes self-power supply and sensing detection functions based on the frictional volt effect, realizes high-sensitivity detection of physical quantities such as flow rate and acceleration, and effectively improves the portability and power consumption ratio of equipment.

This invention discloses a method and application for designing and screening orthogonal loops based on mesophilic Argonaute, belonging to the field of biosensing technology. It includes the construction of a gDNA screening strategy, the design of orthogonal loops based on mesophilic Argonaute, the batch screening and generation of target gene detection sequences, the construction of polystyrene microsphere readout probes, and a machine vision-based microscopic imaging readout method. This invention screens detection sequences to determine candidate orthogonal gDNA sequences, then generates corresponding guide sequences to guide the mesophilic Argonaute to separate the candidate orthogonal gDNA sequences from the detection sequences. The orthogonal gDNA is then used to further guide the mesophilic Argonaute to perform orthogonal cleavage. Simultaneously, the cleavage substrate sequence is mounted on the surface of functionalized polystyrene microspheres as a readout probe, and readout is performed using machine vision-based microscopic imaging technology, achieving sensitive and multiplex one-pot detection of nucleic acid targets.

The invention discloses a preparation method and application of a zinc oxide nanorod collection material and a nitrous oxide sensing film, and the preparation method at least comprises the following steps: mixing and dispersing a zinc compound, carboxylic acid and a sodium hydroxide solution in a solvent, placing in a closed container, and reacting to obtain the zinc oxide nanorod collection material; the rod aggregate material is of a one-dimensional nano structure; the length of the rod aggregate material ranges from 200 nm to 1500 nm. The nitrous oxide sensor based on the zinc oxide nanorod integrated material is high in sensitivity and good in stability, the power consumption of the sensor in the use process is greatly reduced, and the use portability of the sensor is improved.