Application of mycophenolate mofetil in preparing medicine for preventing or treating foot-and-mouth disease virus infection

A foot-and-mouth disease virus and mycophenolate mofetil technology, applied in antiviral agents, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the increased risk of virus strain introduction, the threat of foot-and-mouth disease prevention and control, and the difficulty of specific treatment of foot-and-mouth disease And other issues

Inactive Publication Date: 2019-05-14
LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
View PDF0 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has been found that the virus includes 7 serotypes including A, O, C, Asian I, and South African I, II, and III. At the same time, each serotype is divided into multiple subtypes, which can be used for specific treatment of foot-and-mouth disease. come with great difficulty
In addition, in recent years, the risk of introduction of foreign strains has increased, posing a major threat to the prevention and control of foot-and-mouth disease in my country

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of mycophenolate mofetil in preparing medicine for preventing or treating foot-and-mouth disease virus infection
  • Application of mycophenolate mofetil in preparing medicine for preventing or treating foot-and-mouth disease virus infection
  • Application of mycophenolate mofetil in preparing medicine for preventing or treating foot-and-mouth disease virus infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1. Experimental materials

[0028] 1.1 Cells, Animals, Viruses and Drugs

[0029] IBRS-2 cells were preserved by our research group; 3-day-old suckling mice were purchased from the Experimental Animal Farm of Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences. FMDV (O / MY98 / BY / 2010 and A / GDMM / CHA / 2013) was preserved and provided by the National Foot-and-Mouth Disease Reference Laboratory; MMF was purchased from MCE Company and prepared in DMSO.

[0030] 1.2 Reagents

[0031] DMEM, fetal bovine serum FBS, and trypsin medium were purchased from Gibco; MTS detection kit was purchased from Abcam; TRIZOL was purchased from Invitrogen; SYBRPremix Ex Taq Ⅱ The kits were purchased from Bao Biological Engineering (Dalian) Co., Ltd.; RIPA lysate, BCA method protein quantification kit, SDS-PAGE gel preparation kit, ECL were purchased from Biyuntian Company; BSA and PVDF membranes were purchased from BioRad Company; Tween-20 and Tween-80 were purchase...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to application of mycophenolate mofetil in preparing a medicine for preventing or treating the foot-and-mouth disease virus infection, and belongs to the technical field of veterinary medicines. The By means of the application, the efficient, safe and quality-controllable foot-and-mouth disease virus medicine can be provided for further controlling the spreading of the foot-and-mouth disease.

Description

technical field [0001] The invention relates to the technical field of veterinary medicines, in particular to the application of mycophenolate mofetil in the preparation of medicines for preventing or treating foot-and-mouth disease virus infection. Background technique [0002] Foot-and-mouth disease is an acute and severe infectious disease caused by foot-and-mouth disease virus, which mainly infects artiodactyls such as pigs, cattle, sheep and various wild animals, causing huge economic losses. Because of the seriousness of its impact, the World Organization for Animal Health lists foot-and-mouth disease as the first class A infectious disease, and my country's Ministry of Agriculture also lists it as the first class of animal diseases. The causative agent of foot-and-mouth disease, foot-and-mouth disease virus (FMDV) is a non-enveloped single-stranded positive-sense RNA virus belonging to the family Picornaviridae FMDV. It has been found that the virus includes 7 seroty...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/5377A61P31/14
Inventor 常惠芸龚美娇李世芳邵军军赵付荣常艳燕张永光
Owner LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap