67results about How to "Inhibition has" patented technology

The present invention provides a kind of benzothiobiazole substituent formamidine derivative and benzothiobiazole methanamide derivative, their synthesis method and application. Said invention also provides their structure formulae in which 10 formamidine derivatives containing benzo [1,2,3] thiobiazole substituent and 10 substituted benzo [1,2,3] thiobiazole-7-methanamide derivatives. These compounds have the activity for resisting tobacco mosaic virus and inducing tobacco to resist tobacco mosaic virus and microbiostatic action for inhibiting agricultural fungi.

The invention relates to a preparation method of a nutrient soil for promoting succulent plant growth. The invention also relates to the nutrient soil for promoting succulent plant growth. The nutrient soil for promoting succulent plant growth is prepared from the following components in parts by weight: 25 to 39 parts of akadama soil, 5 to 15 parts of pelelith, 5 to 15 parts of enteromorpha, 3 to 10 parts of sargassum thunbergii, 2 to 10 parts of sargassum fusiforme, 5 to 10 parts of folium artemisiae argyi ash, 5 to 10 parts of plant ash, 5 to 15 parts of bentonite, 3 to 10 parts of peach gum, 5 to 10 parts of cortex dictamni radicis, 3 to 8 parts of indigo naturalis, 3 to 9 parts of radix sophorae flavescentis, 1 to 6 parts of radix stemonae, 1 to 7 parts of rhizoma atractylodis macrocephalae, 1 to 8 parts of bone meal, 1 to 4 parts of monopotassium phosphate, and 1 to 4 parts of microelement. The nutrient soil provided by the invention can be beneficial to effectively improving succulent plant growth.

The invention belongs to a method for preparing inula japonica plant extract and applications of the inula japonica extract. The plant material (root, stem, leaves, inflorescence and whole grass) of the inula japonica (including Inula japonica and Inula britannica) is crushed and extracted by a solvent which comprises 95% of alcohol; and the extract solution is concentrated to have the same weight with the inula japonica crushed matters, thus obtaining inula japonica extract. The inula japonica extract has obvious inhibition effects to cucumber botrytis cinerea, alternaria solani, cladosporium fulvum, colletotrichum lagenarium, sphaerotheca fuliginea, pseudoperonospora cubensis, potato phytophthora infestans, tomato phytophthora infestans and rhizoctonia cerialis; wherein the inflorescence extract has strong antibacterial activity. The inula japonica extract extracted by alcohol can be matched with suitable solvent and pesticide adjuvant to prepare britannica lactone emulsifiable solution and britannica lactione micro-emulsion of botanical fungicide. The inula japonica extract has obvious effects for preventing cucumber downy mildew, sphaerotheca fuliginea, tomato gray mold and tomato leaf mould, is especially suitable for prevention and control on the fungi diseases to economical crops such as vegetables and the like, and is a botanical fungicide with nuisanceless.

The invention provides a soil remediation agent applied to salinized land and a preparation method thereof. The soil remediation agent comprises high-molecule organic acids, high-molecule organic acid potassium or high-molecule organic acid calcium, active functional bacteria, water-retaining agents, soil penetrating agents and other additives. According to the soil remediation agent, the solubility of calcium sulfate and calcium carbonate in the soil can be improved and cured calcium ions can be activated through combination of complexation of high-molecule polymers, sedimentation and separation of the soil penetrating agents on saline and alkaline ions in the soil and activation of microorganisms on the soil; the activated calcium ions are used for replacing sodium ions absorbed by soil colloid through ion exchange action; the replaced sodium ions are combined with negative functional groups to form water-soluble complex; the water-soluble complex enters below plowing layer along with irrigation water; the harm to the growth of crops is avoided.

The invention relates to a fruit vinegar beverage containing xylo-oligosaccharide, xylitol and corn peptide, belonging to food beverage. The fruit vinegar beverage comprises the components of purifiedwater (63-83%), xylo-oligosaccharide (crystal, 0.5-2%), ylitol (crystal, 10-20%), corn peptide (dry powder, 1.5-5%) and fermented fruit vinegar with the concentration of 4% (5-10%). The components are mixed at the room temperature, sufficiently dissolved, sterilized by a pasteurism and subsequently encapsulated, thus composing the beverage with different component proportions. The fruit vinegar beverage containing xylo-oligosaccharide, xylitol and corn peptide has the advantages of sobering up, protecting liver, beautifying face, eliminating fatigue, reducing blood pressure, reducing cholesterin, reinforcing immunity, stimulating bowels evacuation and the like, has no additives such as sugar, preservative, essence, pigment and the like, has no side effects with proper drinking, and can bewidely applied to general people and special people who drink wine and have the disease of diabetes.

The present invention discloses a Chinese medicine for curing nongonococcal urethritis and its preparation method. Said medicine is made up by using 6 Chinese medicinal materials of gardenia fruit, astragalus root, hedyotis, ophiopogon tuber, mallow seed and picrasma quassioides as raw material through a certain preparation process. Said medicine has the functions of clearing heat, disinhibiting dampness, boosting qi, nourishing yin and inducing diuresis for treating stranguria, and possesses the action of resisting inflammation, resisting bacteria, raising immunity and stopping pain.

The invention identifies low-expression microRNA (miR-146a) in RA (rheumatoid arthritis) inflammatory cells and confirms that the miR-146a has the effects of inhibiting RA synovial fibroblasts (RASFs)and inflammation.

The invention discloses an extraction method of impatiens balsamina glycan and an application of the impatiens balsamina glycan in preparation of an anti-SARS-CoV-2 drug, and belongs to the technicalfield of medicines. The extraction method comprises the following steps 1, crushing dried impatiens balsamina plants to obtain impatiens balsamina powder, 2, adding deionized water of which the mass is 18-22 times that of the impatiens balsamina powder into the impatiens balsamina powder to obtain a mixed solution, heating the mixed solution, and adding cellulase, amylase and proteolytic enzyme for enzymolysis for 1-1.5 hours to obtain an enzymolysis solution, 3, heating the enzymolysis solution to 100-110 DEG C, keeping the temperature for 1-1.2 hours, and then cooling and filtering to obtaina filtrate, 4, heating and concentrating the filtrate to obtain a concentrated solution, and then dialyzing for 2-3 days to obtain a dialysate, 5, heating, concentrating and centrifuging the dialysate, removing precipitates, adding 95% ethanol with the volume 5-6 times that of the supernatant, standing overnight, and carrying out alcohol precipitation to obtain an alcohol precipitation solution,and 6, carrying out centrifugal treatment on the alcohol precipitation solution to obtain precipitates, and alternately washing the precipitates with absolute ethyl alcohol and acetone for 3-5 times to obtain the washed precipitates, namely impatiens balsamina glycan.

The invention relates to a lettuce planting method, comprising the following steps: soil preparation and fertilization, seed treatment, sowing and seedling raising, seedling management, field planting, and harvesting. The planting method of the invention can increase the content of protein, vitamin A and vitamin E in lettuce, and can reduce pesticides The residues in plants are beneficial to people's consumption.

The invention relates to a spray for treating asthma which contains active ingredients of Chinese medicinal herbs including 5-500g / L of beta-asaricin and pharmaceutically acceptable solvent. The invention has the advantages of less dosage, uniform medicament distribution, quick medicament adsorption speed, prevention of irritation to stomach and intestine, high biological availability, and ease in use.

The invention relates to application of mycophenolate mofetil in preparing a medicine for preventing or treating the foot-and-mouth disease virus infection, and belongs to the technical field of veterinary medicines. The By means of the application, the efficient, safe and quality-controllable foot-and-mouth disease virus medicine can be provided for further controlling the spreading of the foot-and-mouth disease.

An application of tuduranine hydrochloride in preparing the medicines for treating cerebral glioma is disclosed.

The invention belongs to novel application of plantamajoside in resistance of myocardial hypertrophy and particularly relates to application of plantamajoside in preparation of anti-myocardial hypertrophy drugs. An isoproterenol is adopted for inducing a myocardial hypertrophy model of a mouse and an H9c2 cardiomyocyte hypertrophy model, and meanwhile, intervention is carried out on plantamajosidedifferent in concentration; cardiac functions of the mouse are evaluated through ultrasound, the heart of the mouse and the left ventricular are weighed, and the myocardial hypertrophy degree of themouse is evaluated. The area of H9c2 cardiomyocytes is observed by means of fluorescence staining, and results show that plantamajoside has a protection effect on isoproterenol-induced myocardial hypertrophy of the mouse and an inhibitory effect on isoproterenol-induced H9c2 cardiomyocyte hypertrophy. Plantamajoside is expected to be developed for clinical use in the anti-myocardial hypertrophy drugs.

The present invention relates to a new medicinal part of Chinese medicine, namely, the purpose of biliary konoha in preparing antibacterial, anti-inflammatory and analgesic drugs. Studies show that biliary konoha includes alkaloid and flavonoid similar to konoha and these two ingredients have similar antibacterial, anti-inflammatory and analgesic pharmacological activity. The biliary konoha is extracted by water or ethanol of appropriate concentration; the extracted liquid is merged and filtered; the ethanol is washed through a macroporous resin column and the eluate is decompressed, concentrated and dried to obtain the biliary konoha extract including alkaloid and glycoside compounds. The extract mixed with an appropriate number of pharmaceutical auxiliary materials can be manufactured into oral solid dosage such tablet, capsule, granule and pill according to the conventional preparation process; or injection dosage such as water injection and powder injection according to the conventional injection preparation process.

The invention relates to a feed additive for preventing haemorrhagic septicaemia of ictalurus punctatus and further relates to a preparation method of the feed additive for preventing haemorrhagic septicaemia of ictalurus punctatus. The feed additive for preventing haemorrhagic septicaemia of ictalurus punctatus is composed of the following ingredients in parts by mass: 30-36 parts of couch grass root, 23-29 parts of folium artemisiae argyi, 23-29 parts of garlic juice, 21-29 parts of white gourd seeds, 21-29 parts of lophatherum gracile, 20-27 parts of fructus cnidii, 20-27 parts of divaricate saposhnikovia root, 19-27 parts of sanguisorba officinalis, 19-25 parts of lawn pennywort herb juice, 18-26 parts of rodgersia pinnata, 18-26 parts of Japanese pearlwort herb, 17-27 parts of common cephalanoplos herb, 16-25 parts of heartleaf houttuymia herb and the like. The feed additive for preventing haemorrhagic septicaemia of ictalurus punctatus can effectively avoid haemorrhagic septicaemia.

The invention belongs to the technical field of food preservation and particularly relates to a natural mixed bacteriostatic agent and a preparation method thereof. The natural mixed bacteriostatic agent comprises chlorogenic acid, dihydromyricetin and procyanidine. The natural mixed bacteriostatic agent is prepared by the steps of mixing chlorogenic acid, dihydromyricetin and procyanidine in a certain proportion, adding a certain amount of water solution, adequately stirring to dissolve, and regulate the pH value of the solution. The natural mixed bacteriostatic agent has relatively good inhibition effect to 11 different bacteria including staphylococcus aureus, escherichia coli, Shigella flexneri, proteus mirabilis, Pseudomonas aeruginosa and the like and is expected to be used as an environment-friendly, safe and efficient preservative to be applied to food processing.

The invention relates to an organic fertilizer, and in particular relates to an organic fertilizer for planting lettuce. The invention also relates to a preparation method of the organic fertilizer for planting the lettuce. The organic fertilizer for planting the lettuce is prepared from the following components in parts by mass: 28-49 parts of rotten faeces, 10-18 parts of gelidium, 12-20 parts of purslane, 11-16 parts of fennel, 5-13 parts of water chestnut, 8-16 parts ofpotentilla chinensis, 5-17 parts of trace elements, 5-14 parts of moxa leaves, 5-15 parts of folium ilicis purpurea dreg, 5-15 parts of gardenia, 1-6 parts of urea, 2-6 parts of calcium superphosphate and 2-5 parts of compound bacteria. The organic fertilizer for planting the lettuce can be directly applied, and is simple in preparation process and high in utilization rate.

The invention discloses sculellaria barbata glycan, an extraction method thereof, and an application of the sculellaria barbata glycan in the preparation of anti-SARS-CoV-2 drugs, and belongs to the technical field of drugs. The method for preparing the sculellaria barbata glycan comprises the following steps: 1, crushing dried sculellaria barbata plants to obtain sculellaria barbata powder; 2, adding deionized water into the sculellaria barbata powder, adjusting the pH value of the sculellaria barbata powder to 4.6-4.8 to obtain a mixed solution, heating the mixed solution to 50-60 DEG C, then adding cellulase, pectinase and papain, and performing enzymolysis for 35-45 min to obtain an enzymolysis solution; 3, heating the enzymolysis solution to 100-110 DEG C, keeping the temperature for1-1.2 hours, and then cooling and filtering to obtain a filtrate; 4, heating and concentrating the filtrate to obtain a concentrated solution, and dialyzing the concentrated solution with flowing water for 2-3 days to obtain a dialysate; 5, heating, concentrating and centrifuging the dialysate, removing obtained precipitate, adding 95% ethanol with the volume 5-6 times that of the obtained supernatant, and standing overnight for out alcohol precipitation to obtain an alcohol precipitation solution; and 6, carrying out centrifugal treatment on the alcohol precipitation solution to obtain a precipitate, and alternately washing the precipitate with absolute ethyl alcohol and acetone for 3-5 times to obtain the sculellaria barbata glycan.

The invention discloses an extraction and separation method and application of homogeneous morinda citrifolia polysaccharides, belonging to the field of extraction, separation and application of polysaccharides. The invention aims to solve the technical problems that components are easy to damage, consumed time is long, an extraction rate is low and the pharmacological action of the morinda citrifolia polysaccharides is not clear in conventional morinda citrifolia polysaccharide extraction methods. The method comprises the following steps: preparing coarse morinda citrifolia powder; carrying out flash extraction, concentration, alcohol precipitation, concentration and drying to obtain crude morinda citrifolia polysaccharides; carrying out deproteinization treatment and decoloration; and carrying out elution by adopting a DEAE-52 fiber column, and carrying out Sephadex G-75 gel column chromatography so as to obtain five kinds of homogeneous morinda citrifolia polysaccharides. Accordingto the invention, a morinda citrifolia polysaccharide extraction method is improved and optimized, effective components in morinda citrifolia can be reserved to the maximum extent by utilizing a flashextraction method, extraction time is remarkably shortened, and extraction efficiency is greatly improved. It is verified that the homogeneous morinda citrifolia polysaccharides have an inhibiting effect on human hepatoma carcinoma cells (HepG2). The homogeneous morinda citrifolia polysaccharides extracted by the method are applied as bioactive components for inhibiting human hepatoma carcinoma cells to preparation of antitumor drugs.

The invention relate to a chemical synthesis medicine piperinic acid potassium and galactophore breast cancer medicine application thereof. The galactophore breast cancer medicine piperinic acid potassium (GBK), has the constitutional formula of (img file = 'DDA0001120257960000011.TIF' wi = '686' he = '291' / ), the appraisal of pharmacological effect of the galactophore breast cancer medicine piperinic acid potassium proves that, piperinic acid potassium has inhibiting functions for the multiplication of tumor cells, while has no effect on the multiplication of normal cells, therefore, can be developed as a new anti tumor clinical medicine, or be combined with existing anti tumor medicines, and further can be developed to an anti tumor supplementary medicine of low toxicity, and selectivity.

The invention relates to fish feed and especially relates to Siganus oramin mixed feed and a preparation method of the Siganus oramin mixed feed. The Siganus oramin mixed feed comprises, by mass, 23-30 parts of fish meal, 7-15 parts of wheat bran, 8-14 parts of rice bran, 4-9 parts of corn flour, 6-10 parts of fructus forsythia, 3-8 parts of folium isatidis, 3-7 parts of humifuse euphorbia herb, 3-7 parts of pith of Juncus effusus L., 2-5 parts of paris polyphylla, 2-6 parts of fortune eupatorium herb, 1-5 parts of chrysanthemum indicum, 1-4 parts of radix sophorae subprostratae, 2-6 parts of fish oil, 1-4 parts of honey, 1-4 parts of olive oil and 1-4 parts of composite vitamins. Through use of the Siganus oramin mixed feed, Siganus oramin has a low feed coefficient and has high muscle crude protein content and high flavor amino acid content.

The invention relates to fish feeds and especially realtes to a complex feed for elopichthys bambusa larvae. The invention also relates to a preparation method of the complex feed for elopichthys bambusa larvae. The complex feed for elopichthys bambusa larvae disclosed by the invention comprises the following ingredients in parts by weight: 20-30 parts of dried oyster mushroom, 4-13 parts of corn germ cakes, 6-15 parts of rice bran, 5-14 parts of clam powder, 4-13 parts of gemma agrimoninae, 6-14 parts of fruits of rangoon creeper, 5-16 parts of fructus ulmi macrocarpae, 4-14 parts of omphalia lapialia, 5-14 parts of malt, 6-16 parts of asafetida giant fennels, 3-9 parts of semen raphani, 2-9 parts of purslane, 3-10 parts of fish oil, 1-6 parts of honey, 2-6 parts of olive oil and 1-4 parts of complex multi-vitamins. The invention provides a complex feed for elopichthys bambusa larvae according to the energy metabolism model and the nutritional requirements of the elopichthys bambusa larvae, so as to completely replace fish meal. The elopichthys bambusa larvae fed on the complex feed has the advantages of high survival rate, low feed coefficient and high specific growth rate.

The invention relates to a feed, and in particular to a wild goose mixed feed as well as a preparation method of the wild goose mixed feed. The wild goose mixed feed comprises the following components in parts by mass: 21-29 parts of corn, 5-15 parts of bean pulp, 4-15 parts of peameal, 5-14 parts of fish meal, 6-17 parts of cornstalk, 3-11 parts of bitter herb, 5-16 parts of allium macrostemon, 5-14 parts of sedum aizoon, 3-10 parts of cedrela sinensis, 4-15 parts of water shield, 3-15 parts of dandelion, 3-10 parts of portulaca oleracea, 1-6 parts of lysine, 1-5 parts of calcium hydrophosphate, 1-4 parts of methionine and 1-4 parts of trace elements. The feed coefficient of the wild geese fed with the wild goose mixed feed provided by the invention is low, and the wild goose muscle is high in crude protein content, low in crude fat content and high in flavor amino acid content.

The invention discloses a screening method of a drug for resisting retention-state mycobacterium tuberculosis, which utilizes the change of the light absorption value of an enzyme-labeling instrumentdetection reaction system to judge the inhibition function to the activity of protein kinase G in a sample by adding the sample to be measured into an enzyme activity measuring system, thereby screening a drug for resisting the retention-state mycobacterium tuberculosis. The screening method selects the protein kinase G as a target point and is different from the pervious antitubercular drug whichmainly aims at bacteria with active growth and propagation. The invention aims at solving the difficult problem of long-term incubative infection of mycobacterium tuberculosis by aiming at bacteria which exists in host cells for a long time in a retention state.

The invention relates to an antimicrobial peptide activity feed additive for ducks and a preparation method of the feed additive. The feed additive is prepared from a component A and a component B, wherein the component A is prepared by fermenting 300-500 parts by weight of corn flour, 20-30 parts by weight of apple pomace, 10-15 parts by weight of DDGS, 20-30 parts by weight of corn gluten meal and 100-200 parts by weight of bean pulp through a compound fermentation fungicide; the component B is prepared from 15-20 parts by weight of garden burnet, 12-18 parts by weight of folium isatidis, 8-12 parts by weight of herba artemisiae apiaceae, 1-2 parts by weight of herba polygoni avicularis, 1-2 parts by weight of rhizoma acori graminei, 5-7 parts by weight of cordate houttuynia, 5-8 parts by weight of elegant jessamine, 3-5 parts by weight of potmarigold calendula flower and root, 0.5-1 part by weight of radix bupleuri and 50-80 parts by weight of rice bran. The natural, green and safe feed additive is prepared by carefully selecting the natural raw materials and fermenting or extracting.

The invention provides a medical anti-inflammatory and anti-toxic external cream and a preparation method thereof, which relates to an anti-inflammatory and anti-toxic external cream and a preparation method thereof. The medical anti-inflammatory and anti-toxic external cream is prepared from the following raw materials in parts by weight: 10-20 parts of gromwell, 10-20 parts of curcuma, 10-20 parts of phellodendron bark, 10-20 parts of dyer woad leaf, 10-20 parts of isatis, 10-20 parts of honeysuckle, 10-20 parts of forsythia, 10-20 parts of dandelion, 10-20 parts of cyrtomium fortunei, 10-20 parts of rhubarb, 10-20 parts of giant knotweed, 10-20 parts of radix scutellariae, 20-30 parts of borneol, 40-60 parts of propylene glycol, 150-250 parts of glycerol, 40-60 parts of castor oil, 15-25 parts of Tween 80, 15-25 parts of OP 10 and 25-35 parts of methyl cellulose. The cream provided by the invention is a pure Chinese traditional medicine preparation, can directly act on a focus, has good anti-inflammatory and anti-toxic effects, does not have toxic or side effects, and can be used safely and conveniently.

The invention discloses an externally-applied medicament for radical treatment of all types of cancers and difficult and complicated diseases. The treatment on the difficult and complicated diseases such as cancer and the like by using the externally-applied medicament overturns the traditional treatment modes such as oral administration, operation, chemotherapy and the like, and the externally-applied medicament is externally applied to skin acupuncture points to ensure that the components of the medicament osmoses into a body to eliminate tumors and radically treat the cancer. The medicament mainly comprises the following components: Chinese eaglewood, musk, short-pedicel aconite root, broken immortality peach, clematis root, garden balsam seed, common camptotheca fruit, rubixanthin, borax, centipede, pig bile, common selfheal fruit-spike, glaucescent fissistigma root, dragon bone, olive nut, abrus cantoniensis, decumbent bugle herb and the like. Practices prove that the externally-applied medicament has no side effect in the process of treating cancer and tumor, and the cancers and tumor cannot relapse and transfer; and compared with the traditional therapeutic method, an operation is not needed, oral administration is not needed, injection is not needed, chemotherapy is also needed, and correspondingly, the mental pressure of a patient is alleviated.

The invention relates to a fish feed, in particular to a compound feed for maccullochella peelii, and further relates to a preparation method of the compound feed for the maccullochella peelii. The compound feed for the maccullochella peelii comprises the following components in parts by mass: 21 to 32 parts of fish meal, 7 to 15 parts of small trash fish, 5 to 14 parts of pork powder, 6 to 16 parts of soybean meal, 6 to 14 parts of chinese holly, 3 to 9 parts of pollen pini, 4 to 10 parts of rhizoma atractylodis, 3 to 8 parts of walnut kernel oil, 3 to 7 parts of cloves, 2 to 6 parts of sophora japonica, 2 to 8 parts of lithospermum, 3 to 9 parts of rubia cordifolia, 2 to 8 parts of panax notoginseng, 2 to 6 parts of fish oil, 1 to 4 parts of olive oil and 1 to 4 parts of compound vitamins. After the compound feed for the maccullochella peelii is fed, the feed coefficient of the maccullochella peelii is low; the coarse protein content in muscles of the maccullochella peelii is high, the coarse fat content is low, and the flavor amino acid content is high.