17results about How to "Good synergistic effect" patented technology

The invention discloses a composition with homology of medicine and food and application thereof in relieving physical fatigue, the composition is selected from at least two of ginseng, maca and green tea, and the obtained composition can synergistically regulate oxidation resistance, calcium ion metabolism and energy metabolism, synergistically improve the ATP content and glycogen level of an organism, accelerate removal of lactic acid and urea nitrogen and improve the physical fatigue. And the synergistic effect of the ginseng, the maca and the green tea is better than that of single use of the ginseng, the maca and the green tea. The composition provided by the invention is verified by a standard method of a health-care food function test and evaluation method (2023 edition), and is proved to have a remarkable effect of relieving physical fatigue.

The invention belongs to the technical field of cable harness manufacturing, and discloses a visual auxiliary manufacturing platform and method for cable assembly, and the platform comprises a station operation platform, a small RFID tool cabinet, a large RFID tool cabinet, a station terminal, a secondary central control terminal, and a code scanner. The station operation platforms are provided with workbenches for cable assembly, the secondary central control terminal is connected with the station terminals of the plurality of station operation platforms, each station terminal comprises a display and a host, and the displays provide input, management and display of tools, tasks and parts for operators; the secondary central control terminal provides a dispatch task for the station terminal, and monitors the use of tools, the progress of the task and the consumption of parts through the station terminal; the ID is used for acquiring information of tools and parts; the large RFID tool cabinet is commonly used by a plurality of station operation platforms. A digital technical means and an intensive production mode are adopted, automatic and informationized technological equipment is fused, the technological content of aviation cable manufacturing is improved, and human influence factors are reduced.

The present invention belongs to the field of nanomaterials, and specifically discloses a folic acid-stabilized silver-platinum bimetallic quantum dot-based nanozyme FA@Ag‑Pt QDs, wherein the bimetallic core-shell quantum dot mimetic enzyme has the advantages of high catalytic efficiency, good stability, monodispersity and rapid separation, and exhibits good simulated peroxidase catalytic activity. The FA@Ag‑Pt QDs material is first reduced by fully mixing folic acid with silver ammonium ions through a simple "one-pot synthesis method", so that the two are controllably modified together through non-covalent self-assembly or coordination bonds, and then chloroplatinic acid is added to modify platinum on the surface of nanosilver particles to obtain the method, which is simple in steps, easy to operate, mild in reaction conditions, and suitable for large-scale production. The FA@Ag‑Pt QDs mimetic enzyme prepared by the present invention has good simulated peroxidase catalytic activity, and has great application value in the fields of environmental water, food, and medicine.

A synthesis and an application of a phosphatase degrader, belonging to the field of chemical medicine. The phosphatase degrader is a compound represented by formula I, or a salt thereof, or a deuterated compound thereof, or a stereoisomer thereof, or a solvate thereof, or a hydrate thereof, or a prodrug thereof. The compound can be used as a phosphatase degrader, especially as an SHP2 protein degrader, can treat malignant diseases such as tumors, and has good application prospects.

The invention relates to sleeping milk and a preparation method thereof. The sleeping milk is prepared from the following raw materials: raw milk, theanine, casein hydrolysate, alpha-lactalbumin, sucrose fatty acid ester, glyceryl monostearate, glyceryl distearate, buffer salt and a compound extract, the compound extract comprises a combination of an oat kernel extract, a lotus seed extract, a red date extract and a banana extract. According to the invention, the theanine, the casein hydrolysate, the alpha-lactalbumin and the composite extract are combined for use, and the oat kernel extract, the lotus seed extract, the red date extract and the banana extract are added, so that the four components can interact with one another and have mutual normal-phase influence; the product has an excellent synergistic promotion effect in the aspects of soothing the nerves and helping sleep, and can further improve the sleep-soothing effect of the product after being added into the dairy product.

The invention belongs to the field of biological medicine, and discloses a mesenchymal stem cell-derived exosome and active factor secretion composition and a directional preparation method thereof. According to the method, umbilical cord tissues of healthy mammals are used as raw materials, primary stem cells are separated through enzymolysis, and amplification and passage are conducted to 3-5 generations through an alpha-MEM culture medium; a serum-free induction culture medium containing multiple functional components is adopted for directional induction, a conditioned culture medium is collected, gradient centrifugation and ultrafiltration concentration are performed, and the protein concentration is calibrated to be 2 mg / mL, so that a finished product is obtained. The product can synergistically realize moisturizing, anti-wrinkle and tightening effects. Specifically, the exosome and active factor secreted composition is a composite system which is obtained by separating and concentrating mesenchymal stem cells from a conditioned medium of the mesenchymal stem cells after the mesenchymal stem cells are directionally induced by the method and is mainly composed of the exosome, growth factors self-secreted by the stem cells, cell factors and macromolecular active protein.

The invention relates to the technical field of skin care product raw materials, and particularly discloses an anti-aging composition and a preparation method thereof, the anti-aging composition comprises the following components by mass: 9-10 parts of a composite extract; 4.7 to 5.3 parts of a cell metabolism activator; 0.9 to 1.1 parts of a preservative; 84.6 to 86.4 parts of a solvent; the composite extract is prepared by compounding a dendrobium officinale stem extract, a snow lotus herb extract, a cistanche deserticola extract and a ganoderma spore extract. The anti-aging tea has the advantage of having a better anti-aging effect.

The present invention relates to Lactobacillus rhamnosus, Bifidobacterium longum, and Lactococcus lactis, which are novel lactic acid bacteria. The strains according to the present invention have high utility as a medicine or food and, in particular, can be used for preventing, treating, or relieving inflammatory diseases and neurological diseases, due to having an excellent antioxidant effect, inflammation-relieving effect, nerve-improving effect, cognition-improving effect, intestinal microbiota imbalance-improving effect, etc. In addition, the present invention can be used for regulating and enhancing immunity by increasing the activity of the immune system through immune function-improving and immunity-enhancing effects.

The invention discloses an application of benzalkonium bromide and chlorhexidine in prevention and treatment of plant diseases, and discloses a benzalkonium bromide and chlorhexidine compound composition which has a relatively good synergistic effect in prevention and treatment of the plant diseases and has a very good application prospect.

The application discloses a water-based rust conversion agent, which comprises the following raw materials in parts by weight: water-based styrene-acrylic emulsion 45-55 parts, nano-lotus clay coordination compound liquid modifier 15-20 parts, nano-barium sulfate coordination agent 5-9 parts, rust conversion agent 3-6 parts, defoaming agent 3-5 parts and film-forming aid 1-3 parts. The application has strong wetting and penetrating functions, can penetrate to the bottom of a rust layer to passivate or convert the rust layer, and is suitable for the following fields: steel bar corrosion prevention in a construction site, steel structure workshop manufacturing and maintenance, color steel tile manufacturing and corrosion prevention renovation, shipbuilding, large equipment manufacturing and maintenance, storage tank manufacturing and the like.

This invention relates to a combination of gemcitabine-[phenyl-benzoxy-l-alaninyl]-phosphate (chemical name: 2'-deoxy-2',2'-difluoro-d-cytidine-5'-o-[phenyl(benzoxy-l-alaninyl)] phosphate) (NUC-1031) and a platinum-based anticancer agent selected from cisplatin, picoplatin, lipoplatin, and triplatin. The combinations are useful in the treatment of cancer, particularly gallbladder and bile duct cancer and bladder cancer.

This invention describes a modified silicate-polyurethane two-component grouting reinforcement material, comprising component A and component B, which are mixed in a 1:1 volume ratio before use. Component A, by mass percentage, consists of the following components: water glass: 94%; glycerol: 1%; glyceryl ester compounds: 1%; silane coupling agent: 1%; water: 3%. Component B, by mass percentage, consists of the following components: polymethylene polyphenyl polyisocyanate PM-200: 65%; dibutyl phthalate (DBP): 35%. This invention utilizes the synergistic effect of glyceryl ester compounds and silane coupling agents. The glyceryl ester compounds reduce the interfacial tension between the aqueous and oil phases and promote the uniform dispersion of the silane coupling agent. The silane coupling agent forms a chemical bridge between the inorganic and organic phases, enabling the originally incompatible aqueous and oily agents to form a homogeneous and compatible system. The resulting solidified body has a compressive strength of 24.6 MPa and a bond strength of 3.8 MPa, making it suitable for seepage prevention and sealing in underground engineering and for surrounding rock reinforcement.

The present application relates to the technical field of metal material surface protection, and in particular, relates to a preparation method of a blue laser cladding additive nickel-copper-based eutectic high-entropy alloy offshore wind power protection material. As one of the core pillar industries of global energy transformation, offshore wind power is long-term served in the extreme marine environment of high temperature, high humidity and high salt mist. The corrosion protection problem of key structural components (such as tower foundation, flange connecting surface, main shaft bearing, gear box shell, etc.) directly determines the operation safety and service life of the wind turbine generator. The present application combines innovative alloy composition design with advanced blue laser cladding technology to prepare a eutectic high-entropy alloy protection layer with excellent mechanical properties and corrosion resistance, providing a new technical solution for long-term protection of offshore wind power equipment. It belongs to the key technical innovation in the cross field of high-end equipment manufacturing and surface engineering.

Provided are a bispecific antibody combination and a use thereof. The bispecific antibody combination comprises a bispecific antibody I and a bispecific antibody II. The bispecific antibody I comprises a CD3-targeting domain and a tumor-associated antigen-targeting domain, and the bispecific antibody II comprises a 4-1BB-targeting domain and a tumor-associated antigen-targeting domain. Further provided are a pharmaceutical composition, a test kit, a kit of parts and an administration device containing the same, and a method of treating cancer by using the same. The concomitant use of the bispecific antibodies not only reduces the exhaustion of T cells, but also significantly facilitates tumor killing at a later stage. Moreover, the concomitant use of the bispecific antibodies, especially when targeting different epitopes of the same tumor-associated antigen or targeting different tumor-associated antigens, produces a strong synergistic killing effect. The use of the bispecific antibody combination and the pharmaceutical composition containing the same provides a potential clinical solution for effectively treating solid tumors.

The present invention discloses a nano-silica sol-enhanced sodium carbonate-activated slag regeneration mortar and a preparation method thereof. In the mortar composition of this scheme, sodium carbonate is used as an activator, which has the advantages of widely available raw materials, small corrosiveness and shrinkage cracking, high later strength, low energy consumption and cost, etc.; and the nano-silica sol in the component can well make up for the shortcomings of slow coagulation speed and low early strength caused by sodium carbonate-activated slag, and at the same time can strengthen the interface transition zone of recycled fine aggregate, significantly improve the strength and bonding performance of the mortar; slag and recycled fine aggregate are both solid wastes, which can improve the utilization rate of solid wastes and reduce landfill and land occupation, which is beneficial to environmental governance and protection. On the one hand, the present invention can significantly reduce the emission of greenhouse gases such as carbon dioxide; on the other hand, it can promote the utilization of solid wastes, alleviate the shortage of natural sand and gravel, achieve significant economic, environmental and social benefits, and has broad prospects for promotion and application.

The invention relates to the technical field of skin care products, and particularly discloses a skin-tightening and anti-wrinkle mask liquid capable of penetrating into the bottom of skin to replenish water. Comprising the following components: a pH regulator, a chelating agent, a humectant, a surfactant, an aromatic, a preservative, a composite extract, a skin conditioner, a solvent, an emulsifier and a thickener, the composite extract is prepared by compounding a wild soybean germ extract, a rhodiola crenulata root extract, a myrothamnus flabellifolia leaf / stem extract, a dendrobium stem extract, an aloe barbadensis leaf extract, a radix sophorae flavescentis root extract, a Ningxia wolfberry fruit extract and a purple coneflower root extract. The moisturizing mask has the advantages that water is quickly replenished, and meanwhile, skin moisture is not prone to loss.

This invention discloses a non-contact method for preserving pork using a composite essential oil emulsion combined with an electrostatic field and modified atmosphere packaging. The prepared composite essential oil nanoemulsion is packaged in polyethylene packaging, and the chilled pork is preserved using an electrostatic field synergistic with modified atmosphere packaging. A simple ultrasonic method is used to prepare a composite essential oil nanoemulsion composed of composite essential oils and Tween 80. This prepared emulsion and cooled, acid-removed pork are then placed in an O2 atmosphere. 2 CO 2 N 2 The product is stored in modified atmosphere packaging bags of polyethylene at 4±1℃. This invention can effectively control the increase in total bacterial count, volatile basic nitrogen, and pH of chilled pork during storage, better maintain the product's textural properties, color, and sensory quality, and extend the shelf life of chilled pork by 4-6 days.