132 results about "ChloraPrep" patented technology

Belonging to the technical field of disinfection, the invention discloses a skin disinfection gel to solve the disadvantages of existing disinfection technologies, especially preoperative disinfection technologies. The skin disinfection gel is composed of the following active components by mass: 1.5%-6% of chitosan, 1.5-10% of chitosan oligosaccharide, 2%-8% of baicalin, 0.5%-2% of chlorhexidine, 0.5%-1.5% of sodium alginate, 2%-5% of agarose, and 1.5%-5% of a mint extract. And the disinfection effect is good. The disinfection gel disclosed in the invention can be used for hand disinfection or skin disinfection in sanitary disinfection or preoperative disinfection, and with excellent disinfection effects and lasting function, it has very good application prospects and economic benefits.

The oral formulations of the present invention comprise: (a) chlorhexidine or a salt thereof; (b) a zinc salt; (c) masking and/or flavouring agents, including: (i) a sweetening agent having an immediate but transient effect and (ii) a sweetening agent having a delayed but prolonged effect; and (d) other conventional components of oral formulations. The formulations are, for example, toothpastes, dentifrices, mouthwashes, chewing gum or lozenges.

The invention relates to sterile cleansing solution for women. The cleansing solution is composed of chitosan with a specific molecular weight and deacetylation degree, chlorhexidine, glycerol, acidifier and purified water. The cleansing solution is applied in the environment with hundred-thousand-level cleanliness, the chitosan and the purified water are mixed to form suspension liquid, acidifier is added in the suspension liquid to adjust the pH value to be within the range from 3.8 to 5.8, and chitosan gel is obtained. The chlorhexidine is additionally taken and is dissolved in the glycerol and is added in the chitosan gel, the chitosan gel is evenly stirred, degasification is conducted, filling sealing is conducted and sterilization is conducted, wherein the acidifier is lactic acid or acetic acid or the mixture of hydrochloric acid and acetic acid, and Co-60 irradiation processing or high-temperature damp and hot sterilization is conducted during the sterilization process. The invention further relates to the manufacturing method of the cleansing solution for curing the gynecological disease and the application of the cleansing solution in preparation of medicines for curing women monilial vaginitis, bacterial vaginitis, trichomonas vaginitis or cervicitis, and the sterile cleansing solution for women can be used for daily hygiene care of the vagina of a woman.

The invention provides a foam disinfectant for medical use. The foam disinfectant consists of chlorhexidine acetate, glycerol, alcohol, grape seed essential oil, an emulsifier op, betaine cocoate, tocopherol, lavender essential oil and de-ionized water. The invention also provides a preparation method of the disinfectant. The foam disinfectant prepared by the invention is rich in foam amount, and the volume content of foam is 40-46%; when the foam disinfectant is heat-stored at 52-56 DEG C, only 0.5-1.0% of foam is reduced after 14d; the foam disinfectant is good in disinfecting effect, and when the foam disinfectant is used for disinfecting skin of hands of a human body, a killing rate on escherichia coli, staphylococcus aureus and pseudomonas aeruginosa within 30s is 99.999-100%, and a killing rate on candida albicans reaches 99.99-100%; the foam disinfectant is long in antibacterial duration, and compared with disinfection with simple using of alcohol, the effective antibacterial duration of the foam disinfectant is increased by 2.5-3 times; and the disinfection is high in volatilizing speed, and the disinfection, after being smeared to the hands, volatilizes within 5-7s without residue on the hands.

The invention relates to a chlorhexidine and oligochitosan-containing pharmaceutical composition, wherein the mass proportion of the chlorhexidine to oligochitosan is (0.1-1):1, the chlorhexidine comprises chlorhexidine acetate, chlorhexidine gluconate, chlorhexidine hydrochloride or chlorhexidine citrate, and the molecular weight of the oligochitosan is less than 5,000. The invention further relates to an application of the pharmaceutical composition in preparing a skin or object surface sanitizer, an application of the pharmaceutical composition in preparing an air-atomizing sanitizer, an application of the pharmaceutical composition in preparing an oral cavity sanitizer, an application of the pharmaceutical composition in preparing a vaginal irrigation solution, or an application of the pharmaceutical composition in preparing vaginal gels. According to the chlorhexidine and oligochitosan-containing pharmaceutical composition, the oligochitosan plays a role in obviously improving the antibacterial action of the chlorhexidine.

The invention discloses a Metronidazole, Clotrimazole and Chlorhexidine Acetate Effervescent Tablet and the preparation method. Each tablet has the following proportion of contents: metronidazole 0.2 gram, clotrimazole 0.16 gram, acetic acid chlorhexidine acetate 0.008 gram, fumaric acid 0.108 to 0.162 gram, tartaric acid 0.012 to 0.018 gram, solium bicarbonate 0.12 to 0.18 gram, starch 0.02 to 0.04 gram, dextrin 0.003 to 0.007 gram, hydroxypropyl cellulose 0.007 to 0.013 gram, talc 0.01 to 0.017 gram, sodium dodecyl sulfate 0.01to 0.02 gram, and proper proportion of povidone K30 water solution. According to the preparation method, the components are mixed to produce granule (1) and granule (2); the talc, sodium dodecyl sulfate and the granule (1) and granule (2) are mixed uniformly; granule content is tested and according to the granule content, the tablet weight is identified for tabletting. The invention overcomes the shortages with prior art, enables the acetic acid chlorhexidine acetate to perform functions normally, performs synergistic effects of the three drugs, and greatly enhances the cure rate. Besides, the frothing volume is high, and within storage period, the quality is stable and the drug effects are not affected.

The invention relates to a cooperatively used combination type preparation for cleaning and sterilizing skin after being bitten or scratched by animals. The purpose of the invention is to provide a cooperatively used combination type preparation for cleaning and sterilizing skin after being bitten or scratched by animals with the characteristics of simple preparation, good stability, ease use and good use effect. The technical solution provided by the invention is as follows: the cooperatively used combination type preparation for cleaning and sterilizing skin after being bitten or scratched by animals is characterized in that the combination type preparation comprises a weakly alkaline cleaner and a skin antibacterial spray; the raw materials of the weakly alkaline cleaner include benzalkonium chloride or benzalkonium bromide, 30% dodecyl dimethyl amine oxide solution and polysorbate 20; the raw materials of the skin antibacterial spray include benzalkonium bromide, or benzalkonium chloride, or chlorhexidine, or chlorhexidine acetate, or chlorhexidine hydrochloride, or chlorhexidine citrate, or 20% chlorhexidine gluconate solution and polysorbate 20. The preparation provided by the invention is applied to the treatments of cleaning and sterilizing the skin wounds after being bitten or scratched by dogs, cats and other animals.

The invention discloses a nano iodine-chitosan cervical disease treating membrane agent and a preparation method of the membrane. The treating membrane is prepared by adding plasticizer and adsorbent to chitosan, povidone iodine, dialkyl quaternary ammonium salt and chlorhexidine acetate used as main effective ingredients. The treating membrane disclosed by the invention has killing activity to multiple pathogenic microorganisms, has no irrigation to mucosa, can relieve itching, arrest bleeding and promote the growth of epidermic tissues, can be used for treating colpitis, trichomonas vaginalis, cervicitis, cervical erosion and other gynecological diseases, has better repair action on vaginal and cervical injury, and can effectively prevent the propagation of venereal diseases such as gonorrhoea, syphilis, AIDS (acquired immunodeficiency syndrome) and the like.

The invention relates to the technical field related to elimination of thalli, and particularly provides a preparation for strongly eliminating vibrios and a preparing method of the preparation. On one hand, provided is the preparation for strongly removing vibrios, wherein the preparation comprises the components in percentage by weight: 65-85% of a first guanidine derivative, 2-12% of a second guanidine derivative and the balance being ethanol, wherein the first guanidine derivative is polyhexamethylene guanidine salt and/or polyhexamethylene biguanide salt; and the relative molecular weightof the second guanidine derivative is 500-1500. The vibrios can be effectively removed by utilizing polyhexamethylene guanidine hydrochloride and chlorhexidine hydrochloride under the specific content. The preparation provided by the invention has a strong removal effect on pathogenic vibrios, such as vibrio parahaemolyticus, vibrio anguillarum, vibrio alginolyticus, vibrio cholerae, vibrio fluorescens and the like, has a good cracking effect on aeromonas hydrophila, aeromonas punctata, escherichia coli, salmonella and other gram-negative bacteria, and has a quite high removal rate after being used for 48 hours.

The invention discloses fresh fruit mint mouthwash, and belongs to the technical field of personal care products. The fresh fruit mint mouthwash comprises the following components in parts by weight: 95 to 98 parts of water, 1 to 2.5 parts of glycerin, 0.5 to 1.2 parts of PEG-40 hydrogenated castor oil, 3 to 5 parts of essence, 0.01 to 0.05 part of saccharin sodium, 0.01 to 0.02 part of menthol, 0.01 to 0.3 part of chlorhexidine digluconate, 0.1 to 0.3 part of cetyl pyridinium chloride, 0.05 to 0.3 part of methyl benzoate, 0.05 to 0.3 part of ethyl hydroxybenzoate, 0.05 to 0.3 part of nipasol, 0.01 to 0.3 part of butoben, 0 to 0.005 part of eugenol and 0 to 0.005 part of limonene. According to the mouthwash, bad breath can be effectively removed, fresh breath can be kept persistent, and antibacterial effects and anti-caries effects can be achieved.

The invention discloses a sprayable metronidazole gel composition. The composition comprises metronidazole, water, a water-miscible solvent, carboxymethylcellulose, gamma-type carrageen glycan and 2000-20000 parts of PEG1 (polyethylene glycol 1). The gel composition is high in physical stability, high in salt-resistant capacity and convenient to use.

The invention provides a temperature-sensitive gel for gynecological antibacterial nursing. Based on the total amount of the temperature-sensitive gel for gynecological antibacterial nursing, the temperature-sensitive gel comprises the following components in percentage by weight: 1.2%-17% of a humectant, 0.2%-0.5% of chlorhexidine acetate, 1.11%-9.4% of a traditional Chinese medicine antibacterial compound, 16%-30% of a temperature-sensitive gel, 3.2%-5.2% of a freshener and 0.3%-0.6% of a preservative, 0.3%-5.05% of a lubricant and 46.07%-61.7% of deionized water, and the temperature-sensitive gel is any two of glucomannan, poloxamer 407 and poloxamer 188. Through combination of the chemical bacteriostatic agent and the main bacteriostatic agent, the gynecological antibacterial temperature-sensitive gel has a more milder and more thorough antibacterial effect, the gelation temperature can be adjusted, the gel is convenient to use and more suitable for human body, and all the components are safe and reliable, and the gel is free of irritation to the human body and free of accumulated toxicity.

The present invention discloses a compound of an chlorhexidine acetate local membrane forming gel, which comprises the components of the following weight percentages comprising 0.5 percentage to 7 percentage of alkyl cellulose, 1 percentage to 10 percentage of etherifying agent, 0.5 percentage to 5 percentage of cross linking agent,75 percentage to 90 percentage of dissolvent, 0.01 percentage to 3 percentage of chlorhexidine acetate. The cross linking agent is the saturated fat or the alcoholic acid, the chemical general formula of which is C_nH_2n+2-m-l(OH)_m(COOH)_l. Among the formula, m or n or 1 is the integer and the n is no less than m, which is no less than 2. 1 is no less than 0 and the result of m plus 1 is 4 to 8. The result of n plus 1 is 4 to 8. In the present invention, the compound of the chlorhexidine acetate local membrane forming gel is applied in the treatment of the local infection in the mucosa or the skin. A water drain protective membrane with smooth property, firm property, wear-resisting property and duration property is formed on the surface of the ulcer when the present invention is applied. Compared with all kinds of local formulation of the chlorhexidine acetate, the membrane formed by the gel compound is not likely to experience fracture, dissolution or corrosion. The membrane has properties of long maintenance time and slow releasing of the medicine. The membrane can be effectively maintained in the skin surface for over 8 hours and the membrane can be effectively maintained on the mouth mucosa surface for over 5 hours.

The invention discloses a sterilization and disinfection solution and a preparation method and application thereof. The sterilization and disinfection solution is prepared from the following raw materials in percentage by mass: 2-3% of radix angelicae, 3.5-5% of herba eupatorii, 1-3% of rhizoma atractylodis, 1.5-3% of menthol, 55-70% of ethanol, 2-6% of chlorhexidine acetate and the balance of deionized water. Ethanol with disinfection and sterilization effects in the components destroys cell walls of bacteria, acts on the interior of the bacteria to coagulate and denature proteins of the bacteria, and hinders metabolic functions of the bacteria. Besides, radix angelicae, herba eupatorii and rhizoma atractylodis are further added into the sterilization and disinfection solution, umbrella hydrocarbon and neryl acetate contained in volatile oil of herba eupatorii have an inhibiting effect on influenza viruses, herba eupatorii and rhizoma atractylodis have a good inhibiting effect on bacteria and viruses, 1.5%-3% of menthol is further added, the smell of the sterilization and disinfection solution can be adjusted, and the smell is fresher and more durable; the chlorhexidine acetate isadded in the sterilization and disinfection solution so that the sterilization effect of the sterilization and disinfection solution is further enhanced.

The invention relates to a method for determining chlorhexidine acetate content in a sanitary towel. A dissoluble sample is prepared aiming at a water-insoluble paper sanitary towel product, detection is carried out under the fixed chromatographic condition at the wavelength of 260nm, and result calculation is carried out through an external standard method, so as to obtain chlorhexidine acetate content data in the sanitary towel. By adopting the method, the problem for detecting the chlorhexidine acetate content in the paper sanitary towel product is solved, the method is high in result accuracy, good in repeatability, good in stability, low in operative difficulty index, and applicable to a plurality of aspects such as production quality control, scientific research and the like, and the detection result can be quickly provided in batches.

The invention discloses bath powder for treating fungal infection, which is prepared from the following raw materials in parts by weight: 0.1 to 0.4 part of chlorhexidine acetate, 3 to 10 parts of benzoic acid, 10 to 20 parts of salicylic acid, 10 to 30 parts of boric acid, 2 to 8 parts of cortex phellodendri extract, 2 to 8 parts of cortex dictamni extract, 2 to 8 parts of radix sophorae flavescentis extract, 2 to 8 parts of golden larch bark extract, 0.001 to 0.004 part of essence and 30 to 60 parts of talcum powder. According to the bath powder for fungal infection, the content of acidic substances such as benzoic acid, salicylic acid and boric acid is controlled, so that the proportion of the acidic substances in the bath powder for fungal infection is reduced, the irritation to skin is reduced, and the bath powder for fungal infection cannot cause secondary damage to the skin; through the combined action of acidic substances such as benzoic acid, salicylic acid and boric acid and traditional Chinese medicines such as cortex phellodendri, cortex dictamni, radix sophorae flavescentis and golden larch bark, the anti-fungal effect is enhanced, and through cooperation of chlorhexidine acetate and a traditional Chinese medicine extract, the antibacterial effect on the skin, especially the inhibition effect on fungal infection, is improved.

The invention relates to skin bacteriostasis liquid for feet. Based on 100.0ml as a unit, 1 unit of finished products of the skin bacteriostasis liquid comprise the following raw material components of 45.0-55.0ml of a diacolation extracting solution, 0.4-0.6g of salicylic acid, 0.4-0.6g of benzoic acid, 0.4-0.6g of boric acid, 0.15-0.25g of chlorhexidine acetate, and the balance ethanol water ofwhich the concentration in percentage by weight is 60-70%, wherein the diacolation extracting solution consists of 0.9-1.1g of cortex dictamni, 0.9-1.1g of golden larch bark, 0.9-1.1g of radix sophorae flavescentis, 0.9-1.1g of cortex phellodendri, 0.9-1.1g of common cnidium fruits, 0.9-1.1g of dandelions, 0.9-1.1g of honeysuckle flowers and 0.9-1.1g of fructus kochiae through diacolation extraction and concentration. The skin bacteriostasis liquid for feet is clarified bacteriostasis liquid, is effective for tinea pedis caused by varied fungi, has good effect on smelling feet caused by mass propagation of bacteria, and is good in effect on biting by mosquitoes. An inhibition zone method is adopted for testing the bacterial inhibition of products, and actual product test effects lie in that the bacteriostasis effect is good when 18mm of staphylococcus aureus, 14.92mm of escherichia coli and 13.48mm of candida albicans are adopted.