16results about "Iodine compound active ingredients" patented technology

Provided herein are methods for providing personalized nutritional supplementation to a subject. Also provided are compositions of personalized nutritional supplementation for subjects in need thereof.

It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphosphocholine analogs are compounds having the formula:or salts thereof, wherein n is an integer from 12 to 24; and R2 is —N+(CH3)3. The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, R1 includes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection / imaging applications, R1 includes a detection moiety, such as a fluorophore or a radioactive iodine isotope.

The application discloses a stable liver cancer embolism emulsion of raltitrexed drug gel and a preparation method and application thereof, and belongs to the field of pharmaceutical preparations. The emulsion is composed of iodized oil embolism agent and raltitrexed drug gel; the raltitrexed drug gel is a nanofiber network hydrogel formed by self-assembly of raltitrexed molecules in an aqueous phase through ultrasonic treatment, and simultaneously serves as an active pharmaceutical ingredient and an emulsion stabilizer. The iodized oil and the raltitrexed drug gel are physically mixed and injected through a three-way valve to form a stable oil-in-water emulsion or a water-in-oil emulsion, and any additional chemical surfactant or cosolvent is not needed. The emulsion has excellent physical stability, and can effectively solve the problems of easy aggregation and sedimentation of a traditional iodized oil emulsion and increased systemic toxicity caused by drug burst release. The emulsion has good embolism effect and drug release behavior, can significantly inhibit tumor growth, and has a wide clinical transformation prospect.

A nutritional composition, a preparation method therefor, and uses thereof are provided. The nutritional composition has the following raw materials in the pre-determined mass ratios: 257-295 parts of proteinaceous substances, 383-395 parts of fatty substances, 632-770 parts of carbohydrates, 58-60 parts of dietary fiber substances, 4.7-5.6 parts of complexed trace minerals, 106-119 parts of complexed major minerals, 10.7-12.9 parts of multi-vitamins, 6.21-7.62 parts of choline bitartrate, 0.986-1.1 parts of L-carnitine, and 0.42-0.762 parts of taurine.

The present disclosure concerns a composition for treating arthritis. The composition comprises astaxanthin, a seaweed calcium composition, collagen, calcium fructoborate, a Terminalia chebula extract, and a palm fruit extract. The present disclosure is also related to a method for treating arthritis, comprising administering a composition of the present disclosure to a subject to alleviate a symptom of arthritis.

The present invention provides a gel-forming ophthalmic composition comprising povidone iodine, a steroid, a polysaccharide polymer gelling agent, water, and suitable excipients for ophthalmic preparations. This composition is not only stable, but also can effectively kill a variety of pathogens, rapidly alleviate associated signs and symptoms, and treat ocular diseases.

A method is provided for treating CD33-positive hematopoietic malignancies such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with mutations such as FLT3, IDH1, IDH2, NMP1, and / or MLL1 gene mutations using combination therapy comprising one or both of a radiolabeled CD33 targeter and a drug-conjugated CD33 targeter, and one or more targeted therapies such as FLT3, IDH, and menin inhibitors.

Provided herein are methods for providing personalized nutritional supplementation to a subject. Also provided are compositions of personalized nutritional supplementation for subjects in need thereof.

The present invention is directed to a pharmaceutical product which includes a liquid formulation comprising levothyroxine or a pharmaceutically acceptable salt thereof. The formulation of the present invention includes a cyclodextrin, water, and an amine, and has a pH above the buffering range of the amine. The liquid formulation of the invention is stable and ready-to-use.

The present invention provides a nutritional composition comprising a pre-treated Lactobacillus reuteri as a probiotic bacterial strain. The nutritional composition can be particularly rich in vitamins and minerals and can be used to improve the muscle condition of a subject, in particular the muscle strength of an infant, toddler or child.

Hydrolyzed collagen compositions are described that are used for treatment of impaired tissue including mucosal tissue or to prevent damage to healthy tissue. These compositions function to treat mucosal tissues found in the digestive, urinary, respiratory and reproductive systems. Oral or topical, site-specific delivery of the compositions may be via liquid, spray, gel, powder, tablet, capsule, or sheet form.

To provide: a pharmaceutical dialysate for maintaining physiological levels of thiosulfate ions in a subject undergoing hemodialysis; and a method of producing the pharmaceutical dialysis solution.SOLUTION: A thiosulfate ion-spiked pharmaceutical dialysate comprises sodium thiosulfate, water, an acid concentrate solution, and a bicarbonate concentrate solution, wherein the thiosulfate ion-spiked pharmaceutical dialysate has a pH greater than about 7.0, wherein a concentration of thiosulfate ions in the thiosulfate ion-spiked pharmaceutical dialysate is 100 micromolar or less, and wherein the thiosulfate ion-spiked pharmaceutical dialysate is used to be administered to the subject together with one or more of copper, fluoride ions, iodine, iron, manganese, magnesium, nitrite ions, phosphorus, selenium, and zinc.SELECTED DRAWING: Figure 1

The present invention relates to nutrient-based solid form formulations comprising (a) a mineral or vitamin (b) a phospholipid, (c) a first agent selected from (c-i) carrageenan and (c-ii) acacia gum, and, optionally, (d) a sucrose ester and / or (e) a starch of plant origin. Furthermore, the present invention relates to compositions comprising at least one of said formulations and their use in treating deficiencies of said minerals and / or vitamins. Finally, the present invention relates to methods for preparing said formulations or compositions.

The invention relates to the use of an antibiotic-free antimicrobial feed additive in a method of improving the health of animals and / or reducing methane production of animals. The invention also provides an antimicrobial composition which is used at a low concentration, an antimicrobial composition which has a low ratio of iodide ions to hydrogen peroxide, and uses of these compositions as antimicrobial agents. The invention also provides the use of an antimicrobial composition in combination with an antibiotic as an antimicrobial agent.