50 results about "Direct stimulation" patented technology

An apparatus and a method for treating a weight disorder in a subject are provided. The apparatus comprising an implantable device such as an inflatable balloon and electrodes capable of sensing a physiological change associated with food ingestion or hunger and a mechanism adapted for directly stimulating a region such as the duodenum which is responsive to a gastrointestinal satiety agent, such a mechanism can be a drug reservoir containing a drug such as CCK or analogs thereof which is contained within an inflatable balloon being implantable in a stomach of the subject. The apparatus and method provided here combine synergistic approaches to limiting meal size, i.e., chemo and mechano receptor activation of vagal satiety stimuli, electric stimulation of specific vagal pathways and limitations of gastric space.

This novel therapeutic (reparative, etiotropic not merely symptomatolytic) electrostimulatory method hereinafter referred to as Coupled Neuraxial Mesoscopic Desynchronization Electrostimulation Therapy (cNMDET) is comprised of a varied combination of progressively sequenced electrode placements and its clinically targeted areas which are comprised of the CNS [regions of the brain and spinal cord including, but not limited to, the underlying clinicopathologic mechanisms of the ANS] and clinically involved components of the PNS variably coupled in such a manner as to apply this therapeutic electrostimulation (reparative modulation) along the coursing path (longitudinally) of the targeted neural pathway over a segment and / or in its entirety, as well as, the utilization of patterned applications for involved joints, muscles, fascia, ligaments, tendons and areas involved in inflammatory processes of clinical significance accomplished through the application of, preferably, but not limited to, Coupled Neuraxial Transcutaneous Electrical Nerve Stimulation (cNTENS) and Coupled Neuraxial Transcranial Direct Stimulation (ctDCSn).

Untethered micro or nanoscale probes may be dispersed within tissue to be individually addressed through external electromagnetic radiation to create local electrical currents used for direct stimulation, alteration of cellular potentials, or the release or modification of contained or attached chemical compounds.

This system gives the experimenter great flexibility to present spatio-temporal stimulation patterns to a subject. A video configuration file (VCF) editor allows the experimenter to determine the electrical stimulation parameters for each electrode. A Pattern Stimulation software program allows direct stimulation of chosen patterns of electrodes, scaled by the subject's VCF, through a Graphical User Interface. The subject then responds by drawing the outline of the phosphene he or she perceives on a touchscreen. The Pattern Stimulation program saves all of the trial parameters and the parameters of an ellipse fit to their drawing, as well as a raw data file containing the input to the touchscreen is saved. After the experiment, offline image analysis can be performed to obtain a detailed quantitative description of the subject's percepts. Image descriptors can assigned to the touchscreen data; these image descriptors can be used to make formalized comparisons between various experimental conditions. Various types of image descriptors can be used, including simple ellipse fitting, projections of the 2-D drawings onto one-dimensional axes, calculations of Hu moments, PCA, and ICA.

This invention concerns a method for altering an individual's level of consciousness by directing stimulation or inhibition to a CNS locus target region in the individual's brain that is responsible for consciousness.

The invention provides a hangover-alleviating and liver-protecting composition containing rice bran fatty alkanol and a preparation method. The hangover-alleviating and liver-protecting composition comprises the following components: rice bran fatty alkanol and other active components according to a ratio of 1:1 to 1:100, wherein the other active components comprise the following materials in percentage by weight: 30 to 100% of semen hoveniae powder, 0 to 70% of yeast powder, and 0 to 70% of lactobacillus rhamnosus. The hangover-alleviating and liver-protecting composition has the advantages that the rice bran fatty alkanol is compounded with other active components, so that the better hangover-alleviating and liver-protecting effects are realized; the direct stimulation of alcohol to thedigestive tract after drinking is fully alleviated, and the metabolism of the alcohol is accelerated to relieve the damage to the organs and systems of human body by the product of alcohol in the metabolism process of the human body; the hangover-alleviating and liver-protecting composition is prepared into the tableted candy, the processing is convenient, the cost is economic, the marketing is easy, the convenience in use is realized for a consumer, the willing of a consumer is high, and the market application prospect is very broad.

The invention discloses multi-flavor nutrient kadsura longepedunculata chili sauce. The chili sauce disclosed by the invention is prepared from the following raw materials in parts by weight: 120-130 parts of red chili, 8-14 parts of mung bean starch, 12-13 parts of salt, 10-15 parts of Sanhua wine, 8-9 parts of rose flower petals, 7-9 parts of dried meat floss, 11-15 parts of thin sheets of bean curd, 8-9 parts of apples, 0.9-1.2 parts of globeamaranth, 0.9-1 part of loquat leaves and 1.4-2 parts of kadsura longepedunculata. The chili sauce prepared by the preparation method disclosed by the invention is fragrant, mellow and delicious; nutrient components of the chili are preserved to the most extent; the mung bean starch is added to the raw materials, so that after the mung bean starch is pasted, a layer of protective film can be formed on a gastric wall, direct stimulation of the chili to the gastric wall is avoided or reduced, and gastric mucosa is protected; through the addition of food materials of the globeamaranth, the loquat leaves, the kadsura longepedunculata and the like, the chili sauce disclosed by the invention has the health-care functions of benefiting qi for promoting production of fluid, nourishing the kidney, tranquilizing mind, clearing away the lung, regulating the function of the stomach, calming the liver and improving eyesight.

The invention discloses a single-film bone conduction earphone with double functions and double sound effects. A cover without holes is mounted at the opening of an accommodating cavity inside an earphone shell in an embedded mode; an audio cable is mounted and arranged on the opposite side, at the position of the opening of the accommodating cavity, of the earphone shell; a vibration assembly and an audio signal input assembly are mounted in the accommodating cavity in the embedded mode; the audio signal input assembly comprises hollow voice coil windings and an audio signal connecting plate; the vibration assembly comprises a cylinder-shaped concentrating flux plate, annular permanent magnets and a cylinder-shaped permanent magnet; heteropolar surfaces of the cylinder-shaped permanent magnet and the annular permanent magnets are tightly adsorbed to the cylinder-shaped concentrating flux plate; the cylinder-shaped concentrating flux plate is coaxially and seamlessly riveted to a circular vibration sound film on the opposite side of the cylinder-shaped permanent magnet. Through the structural design, the earphone can obtain double sound effects by taking bone conduction as the principal thing and taking air conduction as the auxiliary thing, and has double functions that the earphone is suitable for both hearing normal people and hearing handicapped; the earphone is novel in design and simple in structure, and can effectively alleviate burden and direct stimulation for eardrums to relieve early ear hearing loss.

Circuitry within a semiconductor die is analyzed by applying an electric field without necessarily directly accessing the circuitry. According to an example embodiment of the present invention, an electric field is applied to a semiconductor die and used to stimulate circuitry therein. A photoemission response of the die to the electric field is detected and used to detect an electrical characteristic of the die. This is particularly useful in applications where it is desired to direct stimulation to the die from an external source and to also externally detect a response of the die to the stimulation. In this manner, the die can be tested without necessarily directly contacting the die and, when the electric field is applied in a scanning mode over the die, can be effected without necessarily knowing the location of a defect in the die.

An array of pneumatic stimulating nodes with integral pneumatically operable ANDing is disclosed. These stimulating nodes may be used to convey spatial orientation information to an individual in an attitudinally ambiguous situation via direct stimulation of his skin. The stimulating nodes of the instant invention may be arranged orthogonally in an array if this is convenient, or in a wide range of other configurations. The pneumatic stimulating nodes of the invention are comprised of three layers, and upper layer, diaphragm layer, and a lower layer which may be separately injection molded from suitable materials, for example, urethane thermoplastic elastomer, and fused together using radio-frequency welding techniques to form the complete stimulating array.

A household amblyopia pleoptic therapy and an apparatus thereof are based on the traditional vision stimulation therapy and combines the modern vision physiological study result; under the technical level of light, sound, electricity and digital control, the present invention integrates the direct stimulation of a characteristic light source towards the vision and the indirect stimulation of a sound signal towards the visual cortex organically by the united space sensing exercising action of the eye-hand-pallium of the patient, which ensures that the synchronized activity of the cortical cell input by the amblyopia eye is increased, so as to release the level restriction of the vision at the pallium, promote the vision growth and realize the effective treatment of the amblyopia finally. The clinical observation for a plurality of years shows that the amblyopia pleoptic therapy and the apparatus of the present invention are safe and reliable and the curative effect is good.

The invention relates to an amblyopia vision increase treatment method and the system, which combines the modern visual physiology research results on the basis of the traditional after-image vision increase therapy, the invention can allow patients to organically integrate the direct stimulation of a characteristic light source on the vision and the indirect stimulation of the sound signal on the visual cortex by the eyes-hands-brain cortex combined space perception and the central vision fixation training actions on the light, sound, electric and data controlled technical lever, so as to strengthen the synchronous activities of the input cortex cells of the amblyopia eye, further to relieve the suppression of the vision on the brain cortex level, promote vision development and finally realize the effective treatment of amblyopia. The clinical observations of 2 years show that the improved after-image vision increase therapy is an amblyopia treatment method which is safe, reliable and good in efficacy, and the invention especially has the treatment effect which is significantly better than other methods for the non-center watch type and other refractory amblyopia. The system can not only greatly improve efficacy, but also improve the working conditions of the medical staff and enhance working efficiency.

The invention discloses a tacrolimus nanocrystal and an artificial tear compound and preparation method thereof. Tacrolimus is a nanocrystal. The tacrolimus nanocrystal is prepared through a recrystallization method. The artificial tear compound of the tacrolimus nanocrystal comprises a nanocrystal of tacrolimus as a core and a shell layer covering the core; the shell layer comprises a plurality of double layers, and each double layer comprises a sodium carboxymethyl cellulose layer and a cationic polymer layer from inside to outside in sequence; a cationic polymer is at least one of polyallylamine hydrochloride, polylysine and polyethyleneimine. The compound is prepared by a layer-by-layer self-assembling method. The tacrolimus nanocrystal as hydrophilicity, high bioavailability and low toxicity, and the artificial tear compound of the tacrolimus nanocrystal has the effects of reducing direct stimulation of high-concentration medicine and exerting immunomodulatory anti-inflammatory and lubrication synergy. The tacrolimus nanocrystal and the artificial tear compound and preparation method thereof can be applied to preparation of medicine for treatment of ocular diseases.

An ultraviolet super-continuum source with a fiber-optic may be provided with direct stimulation by a laser having a relatively narrow bandwidth, for example, less than the typical Raman shift in the material of the optical fiber to provide a super-continuum source extending for wavelengths below 400 nanometers.

The invention discloses a chicken peanut chili sauce, prepared from the following raw materials in parts by weight: pigskin, chili, konjac glucomannan, lily, sophora flower, green tea powder, chicken paste, wheatgerm oil, inulin, grape seed powder, day lily, peanut kernel, fennel stem and leaf, radix astragali preparata, fiveleaf gynostemma herb, persimmon leaf, spina date seed, mulberry wine and table salt. The pigskin is treated and is compounded with the konjac glucomannan to form colloidal slurry, and the added colloidal slurry enables the sauce to be more fine, thick and smooth, and enables nutritional ingredients to be more stable and uniform, meanwhile an envelope structure is formed to prevent or reduce direct stimulation of the chili sauce to the stomach wall, the gastric mucosa is protected, the spicy mouth feel of the chili is achieved, the fragrant and smooth taste of the pigskin is also combined, the components of the lily, the sophora flower and the like are combined, while aroma enhancement and taste improvement are realized, the effects of removing dysphoria with smothery sensation and easing mental anxiety are achieved, dysphoria irritation of common chili sauce is eliminated, the chicken peanut chili sauce has the functions of benefiting qi for tranquillization, clearing away heat and toxic materials, promoting urination and facilitating feces excretion, and the like by the synergy of traditional Chinese medicine functional components, and eating limits are eliminated.

The invention discloses fish roe and liquorice wheat-flavored spicy and hot chilli paste which is prepared from the following raw materials in parts by weight: 120-130 parts of red pepper, 8-14 parts of mung bean starch, 12-13 parts of salt, 10-15 parts of Sanhua liquor, 3-4 parts of oatmeal, 12-15 parts of sweet water cans, 13-15 parts of fish roe, 13-14 parts of kiwi fruits, 0.7-1.2 parts of cornflowers, 0.9-1 part of liquorice and 1-2 parts of buckwheat leaves. The chilli paste disclosed by the invention is savory and mellow and delicious and maintains the nutritional components of chilli intact to the maximum extent. As the mung bean starch is added into the raw materials, the mung bean starch which is gelatinized can form a protective film on the stomach wall to prevent or reduce direct stimulation of chilli on the stomach wall and protect the gastric mucosa. Moreover, by adding food materials such as the cornflowers, liquorice, buckwheat leaves and the like, the chilli paste disclosed by the invention is endowed with the health-care functions of tonifying spleen and qi and relieving cough and moistening lung.

The invention discloses a remote control therapeutic instrument which comprises a control unit, a sampling unit and an execution unit; the control unit comprises a central controller, a micro processor which realizes wireless communication with the central controller, a wireless receiving module which is electrically connected with the input interface of the micro processor, and a power transmission module which is electrically connected with the output interface of the micro processor; the execution unit comprises an electromagnetic coil which is arranged on an insulating substrate; both electrode ends of the electromagnetic coil are fixedly connected with raised electrodes which are used for the electrical stimulation of acupuncture points; and the sampling unit comprises an electric sensor, an input interface, an A / D conversion module which is electrically connected with the output end of the electric sensor, and an unlimited transmission module which is electrically connected with the output interface of the A / D conversion module. The remote control therapeutic instrument has the advantages of realizing the electromagnetic simulation therapy of a plurality of acupuncture points of a plurality of patients through remote control, and solving the defects of the traditional direct stimulation of acupuncture or wired electro-acupuncture stimulation that injury is caused, infection is easy to occur, and a patient has fear to acupuncture.

A hearing instrument for direct stimulation of the cochlea of a patient, comprising an audio signal source for providing audio signals, a sound processor for generating auditory nerve stimulation signals from the audio signals, a stimulation assembly to be implanted into the cochlea and comprising an electrode array to be located in the basal part of the cochlea for electrical stimulation of the auditory nerve in the basal part of the cochlea and a plurality of optical fibers extending beyond the electrode array into the apical part of the cochlea for optical stimulation of the auditory nerve in the apical part of the cochlea, and a driver unit for providing the stimulation assembly, according to the auditory nerve stimulation signals from the sound processor, with electric stimulation signals for the electrode array and with stimulation light from at least one light source for the optical fibers.

The invention discloses a novel reverse flow type oxygen supply device which comprises an oxygen supply pipe, a shell, a cavity and an air outlet cover. The shell is communicated with the oxygen supply pipe. The cavity is formed in the shell. The air outlet cover is arranged on the front side of the shell and provided with dense air outlet holes. The cavity comprises a reverse flow cavity body and a back flow cavity body which are mutually communicated. The front side of the cavity is provided with the air outlet cover with the dense air outlet holes, so that air reversely flows through the reverse flow cavity body and forms air masses after coming out of the oxygen outlet cover. The novel reverse flow type oxygen supply device is arranged at the required position, and the human body can move more freely; reserve flow is adopted for forming the air masses instead of air speed with pressure, the air masses from the oxygen outlet holes do not have pressure, have no direct stimulation on people, or do not stimulate the lung or cause inflammation either, expired air of people can be dispersed fast, and the phenomenon that people have difficulty in breathing or feel oppressed can be avoided; the expired air and the air coming out of the air outlet holes of the novel reverse flow type oxygen supply device are difficult to mix together, and therefore people can breath the air smoothly just as they breath the air in the atmosphere.

Disclosed is extraocular electrode array equipment for local electric stimulation of the retina. The equipment comprises an eyeball front stimulation electrode array, an eyeball rear recovery electrode array and a programmable multi-channel micro-current stimulator; the eyeball front stimulation electrode array and the eyeball rear recovery electrode array carry out electric stimulation, the programmable multi-channel micro-current stimulator is connected with the eyeball front stimulation electrode array and the eyeball rear recovery electrode array separately and transmits electric stimulation signals with different parameters according to actual stimulation demands, and a direct stimulation mode is adopted for large-area regional electric stimulation or an interference stimulation mode is adopted for local electric stimulation. The equipment can be used for electric stimulation treatment on the local region of the retina, and can also serve as a stimulation method of a minimally-invasive retinal prosthesis to induce the artificial visual experience with a large field of view.

The invention discloses an uncaria slow-release pill preparation and a preparation method thereof. The uncaria slow-release pill preparation is prepared from 10-40 parts by weight of uncarine or rhomotoxine and 50-90 parts by weight of substrates, wherein the substrates comprise 40-60 parts by weight of hydrophilic substrates and 10-30 parts by weight of hydrophobic substrates. In the invention, the uncaria slow-release pill preparation is slowly released by a slow-release technique so that the fluctuation of plasma drug concentration can be effectively reduced, the phenomenon of 'peak valley' generated from frequent administration of the common preparation can be avoided, the utilization rate of the drug is improved, and medical expenses can be reduced; the uncaria slow-release pill preparation reduces the direct stimulation of the drug to gastrointestinal tracts to reduce the generation of side effects of the drugs and be easier for patients to tolerate, is beneficial to long-term treatment and is more beneficial to the treatment of hypertension. In addition, the process is simplified so that the uncaria slow-release pill preparation process is easy to operate, the uncaria slow-release pill preparation is easy to carry and take, the problems existing in the prior art are solved and the purpose of the invention is achieved.

The present invention discloses a lotus lung moistening and brain strengthening fresh lotus root chili sauce which is made of the following raw materials in parts by weight: red chilies 120-130 parts, mung bean starch 8-14 parts, salt 12-13 parts, Sanhua-flavor type liquor 10-15 parts, lotus roots 10-12 parts, chopped candied jujubes 10-15 parts, matcha powder 8-10 parts, polygonatum odoratum 0.8-1 part, citrus aurantium flowers 1-1.2 parts, castanea mollissima leaves 0.7-1 parts. The prepared chili sauce has mellow taste and maximumly preserves the nutritious ingredients in the chilies. The mung bean starch is added in the raw materials, thus a layer of protective film can be formed on the stomach wall after the mung bean starch is pasted to prevent or reduce the direct stimulation of chilies on the stomach wall and protect gastric mucosa; and the additions of polygonatum odoratum, citrus aurantium flowers, castanea mollissima leaves and other ingredients enable the chili sauce to have health-care functions of improving eyesight and strengthening brain, regulating qi and relieving depression, nourishing yin and moistening lungs, and tonifying stomach and promoting salivation.

The invention discloses shelled shrimp cashew chili sauce for soothing nerves. The shelled shrimp cashew chili sauce is prepared from the following raw materials in parts by weight: 120-130 parts of red chili, 8-14 parts of mung bean starch, 12-13 parts of salt, 10-15 parts of Sanhua wine, 8-10 parts of laver powder, 14-15 parts of shelled shrimps, 16-17 parts of fresh broad beans, 12-15 parts of cashews, 1.5-2 parts of albizia bark, 2.8-3.3 parts of wild chrysanthemums and 2.1-2.7 parts of mulberry fruits. The chili sauce prepared by the preparation method disclosed by the invention is fragrant, mellow and delicious; nutrient components of the chili are preserved to the largest extent; the mung bean starch is added to the raw materials, so that after the mung bean starch is pasted, a layer of protective film can be formed on a gastric wall, direct stimulation of the chili to the gastric wall is avoided or reduced, and gastric mucosa is protected; through the addition of food materials of the albizia bark, the wild chrysanthemums, the mulberry fruits and the like, the chili sauce disclosed by the invention has the health-care functions of nourishing yin, tonifying blood, improving eyesight, promoting salivation and resolving stagnation for tranquilization.

The invention discloses Lotus root powder lemon digestion-helping chilli paste which is prepared from the following raw materials in parts by weight: 120-130 parts of red pepper, 8-14 parts of mung bean starch, 12-13 parts of salt, 10-15 parts of Sanhua liquor, 6-7 parts of potato chips, 11-12 parts of fresh lotus plumules, 7-9 parts of lotus leaf powder, 10-12 parts of lemon juice, 2-3 parts of mango seeds, 0.8-1 part of jasmine and 1-2.1 parts of gordon euryale leaves. The chilli paste disclosed by the invention is savory and mellow and delicious and maintains the nutritional components of chilli intact to the maximum extent. As the mung bean starch is added into the raw materials, the mung bean starch which is gelatinized can form a protective film on the stomach wall to prevent or reduce direct stimulation of chilli on the stomach wall and protect the gastric mucosa. Moreover, by adding food materials such as the mango seeds, jasmine, gordon euryale leaves and the like, the chilli paste disclosed by the invention is endowed with the health-care functions of invigorating stomach and helping digestion, enriching yin and nourishing kidney and regulating qi and opening depression.

The invention discloses a bracelet device with a treatment function. The device comprises a glove body and a smart bracelet. Weak current acts on a hand in a low-frequency mode by the aid of various pulse patterns, muscles and nerve ending sensory receptors in the muscles are directly stimulated by the aid of electrode slices, the muscles can unconsciously contract, so that the muscles and nervesaching due to exhaustion or injury are relaxed, local blood circulation is promoted, and pain can be relieved or soothed.

The invention discloses a light adjusting control system based on a physiological detection technology. The light adjusting control system based on a physiological detection technology includes a fixed control terminal and a mobile detection terminal, wherein the fixed control terminal includes a lighting switch control module, a brightness detection module, a color temperature adjusting module, acolor temperature value input module, a central processing unit, and a wireless reception module; and the mobile detection terminal takes a hand ring as a carrier, and includes a pulse detection module, a microprocessor and a wireless sending module. Through scientific and reasonable system structural design, the light adjusting control system based on a physiological detection technology can intelligent determine whether people falls asleep according to detection of pulse values so as to control the switch of the light, and can provide warmer light when people wakes up at night, so as to reduce direct stimulation to the optic nerve of the user in the darker environment. Besides, the light adjusting control system based on a physiological detection technology has the advantages of being simple in structure, being high in reliability, and having good practical and promotion values.

The invention discloses milk-flavored pericarp blood-enriching chilli sauce which is prepared from the following raw materials in parts by weight: 120-130 parts of red pepper, 8-14 parts of mung bean starch, 12-13 parts of salt, 10-15 parts of Sanhua liquor, 14-15 parts of milk dregs, 7-8 parts of sweet osmanthus, 13-14 parts of grape skin, 13-14 parts of muskmelons, 2.5-3 parts of astragalus membranaceus, 2-2.5 parts of prepared rehmannia roots and 1.6-2.2 parts of cucumber leaves. The chilli sauce disclosed by the invention keeps the nutritional ingredients of chilli intact to the maximum extent. As the mung bean starch is added into the raw materials, the mung bean starch gelatinized can form a protective film on the stomach wall to prevent or reduce direct stimulation of chilli on the stomach wall and protect the gastric mucosa. By adding the food materials such as astragalus membranaceus, prepared rehmannia roots, cucumber leaves and the like, the milk-flavored pericarp blood-enriching chilli sauce disclosed by the invention is endowed with the health-care functions of nourishing yin and supplementing blood and clearing away heat and tonifying qi.

The invention provides a folding-bayonet-type-handle paper drinking cup. The paper drinking cup consists of a cup body, an intermediate junction portion and an annular handle, wherein the two sides of the annular handle are provided with bayonets; the intermediate junction portion is stuck onto the cup body of the paper drinking cup; the junction portion and two annular handle pieces form a whole body, and the joint of the junction portion and the two annular handle pieces is provided with two fold lines which are parallel to each other; the two opposite bayonets are respectively formed in the outer edges of the two annular handle pieces. The folding-bayonet-type-handle paper drinking cup is simple and reasonable in structure, low in cost and easy in processing and packaged transportation; meanwhile, the direct contact between palms and the cup body during use is avoided, and the direct stimulation to the palms caused by too-high or too-low temperature liquid in the cup is prevented.