120 results about "Carbamide peroxide" patented technology

Composition and methods that include potassium nitrate for whitening and/or reducing tooth sensitivity. The dental compositions may optionally include a dental bleaching agent, such as hydrogen peroxide or carbamide peroxide. The dental compositions may be applied directly to the person's teeth, or they may be loaded into a comfortable fitting, flexible, thin-walled dental tray and placed over the person's teeth. In that case, the dental compositions will include a tackifying agent, such as carboxypolymethylene, dispersed within a solvent, which assists the composition in retaining the dental tray over the person's teeth as a result of the adhesive properties of the dental composition rather than due to mechanical interlocking of the tray over the person's teeth. The dental compositions may further include anticariogenic and antimicrobial agents.

Composition and methods that include potassium nitrate for whitening and/or reducing tooth sensitivity. The dental compositions may optionally include a dental bleaching agent, such as hydrogen peroxide or carbamide peroxide. The dental compositions may be applied directly to the person's teeth, or they may be loaded into a comfortable fitting, flexible, thin-walled dental tray and placed over the person's teeth. In that case, the dental compositions will include a tackifying agent, such as carboxypolymethylene, which assists the composition in retaining the dental tray over the person's teeth as a result of the adhesive properties of the dental composition rather than due to mechanical interlocking of the tray over the person's teeth. The dental compositions may further include anticariogenic and antimicrobial agents.

PCT No. PCT/CN97/00004 Sec. 371 Date Sep. 17, 1998 Sec. 102(e) Date Sep. 17, 1998 PCT Filed Jan. 20, 1997 PCT Pub. No. WO97/25968 PCT Pub. Date Jul. 24, 1997The invention relates to a tooth-whitening varnish composition, comprising 6-20% of carbamide peroxide, 2-9% of film forming agent and 77-88% of volatile organic solvent, based on the total weight of the composition. The volatile organic solvent is selected from ether, ethylacetate, ethyl alcohol, or acetone. The film forming agent is artificial or natural material selected from cellulose, polyvinyl, butyral, coumarone resin or shellac. The composition can rapidly form films on dry tooth surfaces, and a remarkable tooth-whitening effect can be obtained.

The decomposer film product has a polymeric decomposer layer, a cover layer for protecting the decomposer film from the surroundings and a releasable support liner, which is removed prior to use. The polymeric decomposer film contains a water-soluble or water-insoluble polymeric adhesive material and a decomposition accelerator, which acts to decompose an effective ingredient, such as a steroid hormone, of a worn or unused transderamal patch, when the effective ingredient releasing layer of the patch adheres to the polymer film, so that the pharmaceutical effective ingredient comes into contact with the decomposition accelerator by diffusion. The decomposition accelerator includes a chemically oxidizing substance, preferably urea peroxide, manganese (III) acetate or iron (III) citrate. The water-insoluble polymeric adhesive material is preferably an acrylates adhesive. The water-soluble polymeric adhesive material is preferably polyvinyl alcohol, polyvinyl pyrrolidone, a cellulose derivative or a polyacrylic acid.

The invention provides a single phase whitening dentifrice that includes (i) a whitening agent selected from the group consisting of hydrogen peroxide, a bound peroxide and a solid peroxide (ii) an abrasive and (iii) a substantially anhydrous orally acceptable carrier, for example, polyethylene glycol. The bound peroxide may be hydrogen peroxide and a polymer and/or any peroxide compound and a porous cross-linked polymer, such as polymers of polyvinyl pyrrolidone, polyacrylates, a polymethacrylates, and a polyitaconates. The solid peroxide may be sodium perborate or urea peroxide. The invention also provides methods of whitening the tooth surfaces by contacting the surface with the composition.

Dental bleaching compositions, for example in the form of liquids, gels, creams, pastes and ointments, comprising a peroxide releasing compound and from 1% to 35% by weight of a potassium-containing compound such as potassium nitrate, wherein the potassium nitrate is present in a safe and effective amount to prevent tooth hypersensitivity in the patient during the bleaching process. The potassium nitrate contemplated by the invention is compatible with peroxide yielding bleaching compounds such as peroxide, carbamide peroxide, calcium peroxide, zinc peroxide, magnesium peroxide and sodium perborate. Potassium nitrate is complimentary and synergistic with the peroxide bleaching agents contemplated by the invention and enhances the release of oxygen to the tooth enamel. Also contemplated are methods of bleaching teeth comprising application of the dental bleaching compositions of the invention.

A substantially anhydrous gel useful for bleaching teeth comprising: (i) at least 25% by weight of organic polyol; (ii) less than 3% by weight polyacrylic acid thickening agent; (iii) at least 10% by weight carbamide peroxide (or a chemically equivalent amount of another bleaching agent, such as 3% by weight hydrogen peroxide); (iv) neutralizing agent; (v) chelating agents; (vi) desensitizing agent; and (vii) miscellaneous ingredients such as Cirtoxain(R) and flavorants. The organic polyol is preferably glycerin. The polyacrylic acid thickening agent is preferably a carbomer. The desensitizing agent is preferably potassium nitrate, strontium chloride, potassium citrate, strontium nitrate, or a similarly effective alkali or alkaline earth metal salt of an organic or inorganic acid.

The present invention is a formable dental treatment tray utilizing poly(2-ethyl-2-oxazoline) and a gelatinous active. Blending of the active is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with an active ingredient, such as a peroxide like hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition. The gels are applied to an appropriate backing and dried to a gelatinous state. In use, the active is hydrated and regains adhesiveness. Then the tray is pressed and formed around a user's dental arch to form the customizable tray. Multiple active ingredients may be used, with or without peroxide, for accomplishing desired treatment regimens.

The invention relates to the technical field of fertilizers, in particular to a slow-release fertilizer for potatoes. The slow-release fertilizer for the potatoes comprises the following components in parts by weight: 30-50 parts of nitrogen-phosphorus-potassium compound fertilizer, 8-12 parts of fulvic acid potassium, 8-15 parts of urea phosphate, 2-4 parts of citric acid, 3-8 parts of EDTA-Zn, 8-10 billion/g of bacillus subtilis, 1.8-6.4 parts of a carbamide peroxide-beta-cyclodextrin inclusion compound, 0.8-4.8 parts of a controlled release agent, 1.2-3.6 parts of a water-retaining agent and 6-12 parts of a soil conditioner. The slow-release fertilizer for the potatoes is long in effective period, loss of fertilizer caused by volatilization and leaching can be greatly reduced, and the limited fertilizer and water can be fully absorbed and utilized by plants to achieve integrated water and fertilizer and improve soil. The slow-release fertilizer provided by the invention has excellent water retention and slow-release performance, the fertilizer element utilization is improved, the environmental pollution is reduced and the crop growth is promoted.

The invention provides a chemiluminescent substrate solution, which comprises the following components: 0.2-1.2g/L of Luminol, 0.1-5g/L of cinnamic acid, 0.05-0.6g/L of 4-iodophenylboronic acid, 0.05-0.6 g/L of p-iodophenol, 5-50ml/L of dimethylformamide (DMF), 2.5-7.5 g/L of polyvinyl alcohol (PVA), 5-15g/L of polyvinyl pyrrolidone (PVP), 1.5-5g/L of polyethylene glycol 600 (PEC -600), 1-10g/L of ethylene diamine tetraacetic acid (EDTA), 400,000-4,000,000 unit/L of gentamicin sulfate, 0.1-1.0g/L of carbamide peroxide and 0.1mol/L of tris buffer solution with a pH vale being 9.0. The chemiluminescent substrate solution is a solution which can be directly used, and maintains wide linear detection range, good stability and high sensitivity, thus solving the problem that a traditional chemiluminescent substrate solution consists of a solution A and a solution B which are stored separately; and after the solution A and the solution B are isovolumetrically mixed for 10 minutes, signal values are decreased sharply, the detection range is narrowed and the stability is poor. In addition, the chemiluminescent substrate solution provided by the invention is easy to prepare, low in cost and simple to operate, environmentally friendly, and non-toxic and harmless to human bodies and the like.

The invention discloses a synthetic method of ciprofibrate. The method comprises the following steps: taking styrene as a starting material; obtaining the ciprofibrate by the processes of cyclization, acylation, Baeyer-Villiger oxidation, alcoholysis, alkylation and hydrolysis, wherein an acylation reagent adopted in the acylation process is R1COCl; the R1 is C4-C12 alkyl. Fatty acyl chloride of which a hydrocarbyl structure is a long chain is adopted in acylation reaction, so that the steric hindrance is increased, the reaction activity of acyl chloride is reduced, the content of the produced ortho-position isomer is smaller than 0.2% and superior to that of acetyl chloride reaction (the content of the ortho-position isomer is 0.5-1%), the yield and the purity of the product are improved, and meanwhile, a room-temperature reaction condition is adopted, so that the energy consumption of production is reduced. Urea peroxide instead of hydrogen peroxide is used as an oxidant in the Baeyer-Villiger oxidation, and acetic acid is used instead of acetic anhydride, so that the reaction condition is milder, and the operation is more controllable.

This invention relates to a method for preparing high-stability carbamide peroxide. The method comprises: (1) adding urea and stabilizer into 25-40 wt. % H2O2; (2) stirring so that urea is completely dissolved, and drying to obtain carbamide peroxide crystals. The stabilizer is a mixture of zinc tartrate, tartaric acid and dodecyl benzenesulfonate at a weight ratio of (1-2) : (45-49): (45-50). The mol ratio of urea to H2O2 is 1: (1.0-1.2). The method has such advantages as high yield, simple process, no wastes and high product stability, and is suitable for mass production.

The present invention provides a single-component TMB coloration liquid, which is formed by mixing a liquid A and a liquid B, wherein urea hydrogen peroxide is dissolved in a citric acid-sodium citrate buffer liquid to prepare the liquid A, and polyvinyl alcohol, polyvinyl pyrrolidone, TMB and glycerol are dissolved in a citric acid-sodium citrate buffer liquid to prepare the liquid B. Compared with the single-component TMB coloration liquid in the prior art, the single-component TMB coloration liquid of the present invention has the following advantages that: the stability of the coloration substrate in the solution can be maintained, the operator can be protect from being away from organic solvent hazard, the damage on the environment can be reduced, the stable aqueous solution system can be formed, and the single-component TMB coloration liquid can be stored for 24 months at a temperature of 2-8 DEG C.

Dental bleaching compositions, for example in the form of liquids, gels, creams, pastes and ointments, comprising a peroxide releasing compound and from 1% to 35% by weight of a potassium-containing compound such as potassium nitrate, wherein the potassium nitrate is present in a safe and effective amount to prevent tooth hypersensitivity in the patient during the bleaching process. The potassium nitrate contemplated by the invention is compatible with peroxide yielding bleaching compounds such as peroxide, carbamide peroxide, calcium peroxide, zinc peroxide, magnesium peroxide and sodium perborate. Potassium nitrate is complimentary and synergistic with the peroxide bleaching agents contemplated by the invention and enhances the release of oxygen to the tooth enamel. Also contemplated are methods of bleaching teeth comprising application of the dental bleaching compositions of the invention.

The invention provides a stable HRP (Horseradish Peroxidase) enzyme-catalyzed chemiluminescence substrate solution as well as a preparation method and application thereof. Typically, the stable HRP enzyme-catalyzed chemiluminescence substrate solution is prepared from two components including a chemiluminescence substrate solution A and a chemiluminescence substrate solution B, wherein the solution A is prepared from luminol, p-imidazophenol, sodium tetraphenylborate, dimethylformamide (DMF), sulfobutyl-beta-cyclodextrin, a light stabilizer and a Tris buffering solution with a certain concentration; and the solution B is prepared from polyvinylpyrrolidone (PVP), urea peroxide and the Tris buffering solution. With the adoption of the chemiluminescence substrate solution provided by the invention, the problems of an existing chemiluminescence substrate that the platform phase is short, the stability is relatively poor, the luminous intensity is low, the sensitivity is low and the background is relatively high can be solved.

The present invention is the use of Poly(2-ethyl-2-oxazoline) in the creation of peroxide gels for various applications. Such applications include bleaching of hair, teeth, laundry or any other bleachable item. Blending of the gel is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with a peroxide such as hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition.

As a TMB (Tetramethylbenzidine) color-developing liquor on the market has defects of being poor in stability, short in storage time, high in color-developing background, low in sensitivity, and the like, the invention provides an efficient and stable TMB color-developing liquor. The efficient and stable TMB color-developing liquor is characterized by comprising the following components according to molar concentration or by weight percent: TMB with molar with the concentration of 1.2mmol/L, H2O2 with the molar concentration of 3.1mmol/L, 0.3% of trito X-405, 0.5% of urea peroxide, sodium acetate with the molar concentration of 0.2mol/L, L<+>-tartaric acid with the molar concentration of 0.027mol/L. The efficient stable TMB color-developing liquor is a TMB single-phase color-developing liquor, and not required to be mixed before use, so that errors in the artificial operation process can be reduced; a nonionic surfactant is introduced, so that the single-phase TMB color-developing liquor can be stably stored for a long time.

The invention provides a roughing solution for a diamond-copper composite and a surface nickel plating method of the diamond-copper composite. The roughing solution is composed of, by weight, 1%-10% of nitrite, 1%-10% of strong base, 0.2%-0.6% of alcohol amine, 0.1%-0.8% of carbamide peroxide, 0.1%-0.6% of ferrate and 78%-97.6% of water. The surface nickel plating method comprises the steps that the surface of the diamond-copper composite is subjected to roughing, oil removal, activation, acid pickling and chemical nickel plating in sequence, and according to roughing, chemical roughing is carried out on the diamond-copper composite in the roughing solution. Strong oxidant and strong base are mixed in the roughing solution, so that the problem of a copper biting reaction existing in traditional acidic roughing solution treatment is solved, impurities on the surface of the diamond-copper composite can be oxidized and dissolved, and various organic substances and inorganic substances can be adsorbed; therefore, the effect that the surface of the diamond-copper composite is clean, roughed and hydrophilic can be achieved, and the plating efficiency and quality are improved.

A multi-film delivery system for a multi-component tooth whitening, desensitization and remineralization composition is disclosed which comprises a first orally dissolvable film made of a liquid-soluble or liquid dispersible polymer system containing a peroxide activation compound or complex and desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, and a separate second undissolvable film containing a tooth whitening peroxide compound, such as hydrogen peroxide or carbamide peroxide, stabilizers and thickeners, and/or desensitizing agents and/or remineralizing agents and/or anti-inflammatory agents, which, when applied together on teeth surfaces, the peroxide activation compound/complex on the first film activates the peroxide compound on the second film, and accelerates the release of active bleaching radicals for accelerated whitening action. The first and second films are maintained separate from one another until application. The first orally dissolvable film is placed on a surface of the tooth, then immediately hydrates thereby becoming gelatinous upon contact with saliva, and initiates its adhesiveness, the second undissolvable film is then placed on top of the first orally dissolvable film, the peroxide activation compound/complex on the first film reacts with the tooth whitening peroxygen compound on the second film and accelerates the release of active bleaching radicals for rapid whitening action. The dissolution of the first dissolvable film is controlled by interaction with the fluid or liquid contained in the whitening composition on the second undissolvable film.

The invention relates to a domestic tooth whitener, which overcomes the defects that a domestic tooth whitener has long wearing time, more sensitivity and undefined effect when the domestic tooth whitener is used for treating tetracycline pigmentation teeth, dental fluorosis, and pigment teeth of smoke, lecanorine and the like. The product is a whitening system using urea peroxide as a main component which is added with an activator, a desensitizer and a thickening agent for strengthening the viscosity. Therefore, the product greatly reduces the sensitivity of a patient and the wearing time of a denture base, and reduces the opportunity for reducing the activity of the whitener which is diluted by slobber. Thus, the whitener achieves the exact whitening effect.