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49 results about "Paris polyphylla" patented technology

Paris polyphylla is an Asian species of flowering plant native to China, Taiwan, the Indian Subcontinent, and Indochina. It produces spider-like flowers that throw out long, thread-like, yellowish green petals throughout most of the warm summer months and into the autumn. In the fall, the flowers are followed by small, scarlet berries. It is a perennial, which slowly spreads, is fully hardy in Britain, and survives in leafy, moist soil in either complete or partial shade.

Hemostatic active component, active component and composition of ball medicine paris polyphylla and application of hemostatic active component and composition

The invention belongs to the technical field of phytochemistry and medicines, and discloses a hemostatic active component from paris polyphylla Franch., an active ingredient, a composition and application of the hemostatic active component, the active ingredient and the composition. The active component mainly contains steroid saponin. The invention also relates to a compound with hemostatic activity, and the compound is 21-hydroxy polyphyllin VII. The active component, the active ingredient and the hemostatic active compound provided by the invention are obtained by extracting a paris polyphylla plant material. Experiments show that the active component and the active ingredient of the paris polyphylla pall have a remarkable hemostatic effect and can be used as a medicine for treating hemorrhagic diseases.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Preparation method and application of yunnan rhizoma paridis saponin G

This invention provides a method for obtaining ingredients from Dulong Paris polyphylla (… Paris dulongensis A method for preparing parisyunnanoside G (PFE55) in H. Li & Kurita and its application in cosmetics and pharmaceuticals. This research belongs to the field of cosmetics and pharmaceutical technology. PFE55 is used at extremely low concentrations (0.1... μ At a concentration of g / mL, it exhibits activity in promoting collagen secretion in adult dermal fibroblasts (HDFa) and is non-cytotoxic at this concentration, making it suitable for the preparation of anti-aging drugs or skincare products.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Traditional Chinese medicine composition for preventing hair loss, growing hair and removing dandruff as well as preparation method and application of traditional Chinese medicine composition

PendingCN121987712AImprove dandruff and itchingpromote healthy growthAnthropod material medical ingredientsAntimycoticsAngelica Sinensis RootSchizonepeta tenuifolia
The invention provides a traditional Chinese medicine composition for preventing hair loss, growing hair and removing dandruff as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The invention discloses a traditional Chinese medicine composition for preventing hair loss, growing hair and removing dandruff. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-12 parts of lithospermum, 8-12 parts of paris polyphylla, 15-25 parts of duckweed, 8-12 parts of golden larch bark, 8-12 parts of lucid ganoderma, 15-25 parts of cocklebur fruit, 15-20 parts of gallnut, 8-12 parts of radix sophorae flavescentis, 5-10 parts of schizonepeta, 8-12 parts of radix saposhnikoviae, 4-8 parts of notopterygium root, 5-10 parts of schisandra chinensis, 5-10 parts of elecampane, 5-10 parts of eclipta, 5-10 parts of ginseng, 5-10 parts of angelica sinensis, 5-10 parts of saponin, 5-10 parts of soapberry and 5-10 parts of broadleaf holly leaf. , 8-12 parts of fructus ligustri lucidi, and 4-8 parts of herb of wiss mannii The invention provides a traditional Chinese medicine composition for preventing alopecia, growing hair and removing dandruff, aiming at improving the problems of alopecia, dandruff and scalp discomfort.
Owner:NANYANG AOSHANTANG BIOLOGICAL PHARM CO LTD

Panax notoginseng-Paris polyphylla supramolecular complex, preparation method, cosmetic product and application thereof

This invention provides a Panax notoginseng-Paris polyphylla supramolecular complex, its preparation method, cosmetic products, and applications. The Panax notoginseng-Paris polyphylla supramolecular complex is a complex formed by non-covalent bonding of Panax notoginseng extract (as the host molecule) and Paris polyphylla extract (as the guest molecule), with the host molecule encapsulating the guest molecule structure. The Panax notoginseng-Paris polyphylla supramolecular complex of this invention not only improves the water solubility of Paris polyphylla extract but also increases its skin permeability and reduces its cytotoxicity. The preparation method of this invention utilizes the synergistic effect of the active ingredients, resulting in strong compatibility and synergistic efficacy. It also slows down the release time of the active ingredients, extends their shelf life, and features a simple and easy-to-control process, stable granulation effect, and low production cost.
Owner:云南白药集团上海科技有限公司

Traditional Chinese medicine combined powder for rapidly treating various burns and scalds

The invention discloses traditional Chinese medicine combined powder for rapidly treating various burns and scalds, and relates to the technical field of traditional Chinese medicine formulas. Traditional Chinese medicine combined powder for rapidly treating various burns and scalds is characterized in that the active ingredients of the powder comprise 6-10 parts by weight of polygonum cuspidatum, 3-9 parts by weight of coptis chinensis, 4-10 parts by weight of paris polyphylla, 6-12 parts by weight of rhizoma bletillae, 15-30 parts by weight of calcined dens draconis, 3-9 parts by weight of spar and 0.1-0.3 part by weight of pearl. The combined medicine powder has the effects of clearing away heat and toxic materials, promoting tissue regeneration, relieving pain, promoting wound repair and enhancing local microcirculation of the wound, the medicine powder generally needs to be combined with sesame oil for use, the core components of the medicine powder, namely polygonum cuspidatum and coptis chinensis, synergistically exert broad-spectrum antibacterial and antioxidant effects, and paris polyphylla and rhizoma bletillae enhance the barrier function of the wound; the calcined dens draconis and the kyanite promote activation of a calcium ion channel, and the pearl can regulate and control ordered deposition of collagen and reduce scar hyperplasia.
Owner:汤学庚

Preparation and application of paris-polyphylla-based nitrogen-doped fluorescence enhanced carbon dots Pol-CDs

The invention discloses preparation and application of paris-based nitrogen-doped fluorescence-enhanced carbon dots Pol-CDs, a dark brown crude Pol-CDs solution is obtained from polyphyllin and o-phenylenediamine according to the feeding ratio of 1: (1-20) through a hydrothermal method, DMF or ethyl alcohol or methyl alcohol or acetone or THF serves as a solvent, then purification is conducted through dialysis, thin-layer chromatography and a chromatographic column, and green fluorescent Pol-CDs are prepared. Due to the selectivity of Pol-CDs, only carbendazim can efficiently sensitize green fluorescence, other pesticide residue molecules do not interfere with one another, and the content of carbendazim in food is detected under the stable condition that the pH value is 8.0.
Owner:YANAN HOSPITAL OF KUNMING CITY

Yao medicine composition with effects of regulating menstruation and stopping bleeding and preparation method of Yao medicine composition

PendingCN121731410ASexual disorderBlood disorderAsparagus cochinchinensisPhysiology
The invention discloses a Yao medicine composition with effects of regulating menstruation and stopping bleeding as well as a preparation method and application of the Yao medicine composition, and belongs to the technical field of ethnic medicines. The composition is prepared from paris polyphylla, radix zanthoxyli, giantleaf ardisia rhizome, ovateleaf holly bark, radix fici simplicissimae and callicarpa macrophylla. The preparation method comprises the following steps: carrying out secondary water extraction on the raw materials, concentrating to specified density, standing, precipitating, removing impurities, preparing and the like. The Yao medicine composition disclosed by the invention not only has a remarkable hemostatic effect, but also has an excellent endocrine regulation function. Pharmacodynamic experiments show that in a rat dysfunctional blood model induced by combination of mifepristone and misoprostol, the composition can significantly reduce the bleeding amount and shorten the bleeding time, the hemostatic effect is equivalent to that of a positive control drug, namely Gongxuening capsule and a pure paris polyphylla extract, and although a paris polyphylla preparation exists, the hemostatic effect of the composition is remarkably improved. However, the problem that a single paris polyphylla preparation is weak in FSH / LH regulation capacity is solved, and data prove that the compound is irreplaceable.
Owner:JINXIU YAO AUTONOMOUS COUNTY YAO MEDICAL HOSPITAL

Probiotic composition for enhancing immunity and preparation method thereof

The preparation method comprises the following steps: mixing and crushing the following components in parts by weight: 10-15 parts of astragalus membranaceus, 2-3 parts of paris polyphylla, 2-6 parts of liquorice, 3-5 parts of pseudo-ginseng, 1-2 parts of pericarpium citri reticulatae, 20-30 parts of American ginseng, 5-10 parts of angelica sinensis and 4-5 parts of fructus gardeniae, and then performing purification treatment to obtain a composition I; 0.02 to 0.05 part of bifidobacterium lactis, 0.02 to 0.05 part of bifidobacterium breve, 0.02 to 0.08 part of lactobacillus rhamnosus and 0.01 to 0.02 part of lactobacillus acidophilus are used for preparing microcapsule powder, and the microcapsule powder is used as a composition II; and mixing the composition I and the composition II according to a mass ratio of (8: 1)-(10: 1) to obtain the probiotic composition for enhancing immunity. The defects in the prior art can be overcome, and the immunity is effectively improved.
Owner:JIACHENG ZHIHE (BEIJING) TECHNOLOGY CO LTD

Novel nano antibacterial skin repair product for preventing hpv virus

The invention relates to the field of repair product preparation, in particular to a novel nano-antibacterial skin repair product for preventing hpv viruses. The formula is prepared from the following raw materials by weight: 0.80 to 4.50 g of purified water, 0.008 to 0.150 g of carbomer, 0.01 to 0.80 g of fenugreek oil, 0.01 to 0.30 g of oat beta glucan, 0.003 to 0.400 g of folium artemisiae argyi extracting solution, 0.01 to 0.40 g of herba portulacae extracting solution, 0.006 to 0.420 g of herba violae extracting solution, 0.001 to 0.200 g of herba lophatheri extracting solution, 0.007 to 0.300 g of herba taraxaci extracting solution, 0.008 to 0.220 g of rhizoma paridis chinensis extracting solution, 0.01 to 0.40 g of herba leonuri extracting solution, 0.0005 to 0.0300 g of nano silver and 0.008 to 0.150 g of borneol. The adhesive comprises the following components by weight: 0.01 to 0.30 g of sodium carboxymethyl cellulose, 0.008 to 0.220 g of lubrajel, 0.007 to 0.300 g of benzoyl peroxide, and 0.0005 to 0.0300 g of a cross-linking agent. The invention has the following beneficial effects: the ointment comprises a plurality of plant extracts, has no irritation to vagina, is safe and has no side effect; the carried antiviral and antibacterial components can rapidly permeate into the skin to protect mucous membrane cells from being damaged by viruses; skin tissues can be quickly repaired, and wound healing and regeneration capacity is improved; various plant extracts in the gel can also improve the immunity of the organism and can achieve a good antiviral effect.
Owner:ZHEJIANG JINGSHUNING BIOTECHNOLOGY CO LTD

Formula of Tibetan medicine plaster for treating pain

The invention discloses a Tibetan medicine plaster formula for treating pain, and relates to the technical field of traditional Chinese medicines, and the Tibetan medicine plaster formula is prepared from the following active raw materials in parts by weight: 10-20 parts of lamiophlomis rotata, 5-10 parts of rhodiola rosea, 15-20 parts of paris polyphylla, 3-10 parts of lemonfragrant angelica root and 10-20 parts of aconitum pendulum. Through the synergistic effect of lamiophlomis rotata, aconitum pendulum and paris polyphylla in a specific ratio, the effects of promoting blood circulation to remove blood stasis and calming and relieving pain are remarkably enhanced, and meanwhile, the qi-tonifying and collateral-dredging component of rhodiola rosea can improve local microcirculation so as to promote medicine permeation and pain area repair; and the lemonfragrant angelica root is used as a channel guiding medicine to effectively improve the transdermal absorption rate of the medicinal components.
Owner:TIBET ZHUOZHENG TIBETAN MEDICINE BIOTECHNOLOGY CO LTD

Application of Paris polyphylla extract in the preparation of cosmetics and pharmaceuticals

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Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Complex microbial inoculant for reducing continuous cropping obstacles of polygonatum kingianum and use method of complex microbial inoculant

The invention provides a complex microbial inoculant for reducing continuous cropping obstacles of polygonatum kingianum and a use method of the complex microbial inoculant, and relates to the technical field of polygonatum kingianum planting. The composite microbial agent is prepared from a pea sprout fermentation material, a zanthoxylum bungeanum leaf fermentation material, first composite bacteria, second composite bacteria, carboxymethyl chitosan, sodium alginate, acid modified starch, silicon dioxide and bentonite. The pea sprout fermented material is prepared by fermenting pea sprouts by adopting trichosporon aryabhattai; the zanthoxylum bungeanum leaf fermented material is prepared by fermenting zanthoxylum bungeanum leaves with lactobacillus plantarum. According to the method, the defects in the prior art are overcome, the continuous cropping obstacle of the polygonatum kingianum can be effectively overcome, meanwhile, growth of newly-planted polygonatum kingianum is promoted, the quality and yield of the polygonatum kingianum are further guaranteed, and the economic benefits of planting are comprehensively improved.
Owner:INST OF MEDICINAL PLANTS YUNNAN ACAD OF AGRI SCI

A traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney deficiency and damp-heat type, accompanied by gastrointestinal dysfunction, and its preparation method.

ActiveCN121513139BDigestive systemSkeletal disorderSpondarthritisLycopodium clavatum
This invention proposes a traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney-deficiency and damp-heat type accompanied by gastrointestinal dysfunction, along with its preparation method, belonging to the field of traditional Chinese medicine technology. The compound consists of Smilax glabra, Bletilla striata, Paris polyphylla, Geranium wilfordii, Dioscorea hypoglauca, Patrinia scabiosaefolia, Dipsacus asper, Drynaria fortunei, Pyrola rotundifolia, Clematis chinensis, Pheretima aspergillum, Lycopodium clavatum, Corydalis yanhusuo, Paeonia lactiflora, Atractylodes macrocephala (fried), Coix lacryma-jobi (raw), Aucklandia lappa, and Glycyrrhiza uralensis. This invention combines these herbs to achieve a synergistic effect, collectively clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. The overall formula addresses both strengthening the body's foundation and eliminating pathogenic factors, ensuring unobstructed meridian flow and relieving arthralgia. This compound has the functions of clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. It offers a short treatment course, rapid efficacy, low recurrence rate after cure, few side effects, and is inexpensive and convenient to use for treating ankylosing spondylitis with gastrointestinal dysfunction.
Owner:FIRST AFFILIATED HOSPITAL OF ANHUI UNIV OF CHINESE MEDICINE

Separation method of extracellular vesicles derived from non-medicinal parts of paris polyphylla and application of extracellular vesicles in anti-inflammatory and whitening

The invention discloses a separation method of extracellular vesicles derived from non-medicinal parts of paris polyphylla and application of the extracellular vesicles in anti-inflammatory and whitening. According to the method, the extracellular vesicles are separated from stems, leaves and root hairs of non-medicinal parts of paris polyphylla by adopting double isoelectric precipitation combined with electrophoresis dialysis, and biological activity research is systematically performed on the extracellular vesicles sourced from the stems, leaves and root hairs. The cell and zebra fish model comprehensive evaluation proves that the extracellular vesicles from the two sources have obvious anti-inflammatory effects. However, in the melanin inhibition activity, the extracellular vesicles of the stems and leaves of the paris polyphylla are good in performance, and the inhibition effect of the extracellular vesicles on melanin generation in a zebra fish in-vivo model and the inhibition capacity of the extracellular vesicles on tyrosinase in vitro are obviously superior to those of a classic whitening agent arbutin. The limitation that only paris polyphylla tubers are utilized traditionally is broken through, development and efficacy verification of the paris polyphylla stem leaf and root hair extracellular vesicles are achieved for the first time, and the application prospect in the aspect of developing anti-inflammatory drugs and whitening cosmetics is wide.
Owner:ZHEJIANG UNIV OF TECH

Hemostatic medicine and preparation method thereof

The invention provides a hemostatic medicine and a preparation method thereof, and belongs to the technical field of medicines. Comprising the following steps that S1, 60% by weight of galium aparine, 30% by weight of paris polyphylla and 10% by weight of lysimachia christinae hance are pretreated, and pretreatment comprises cleaning, drying and processing; s2, carrying out superfine grinding on the pretreated raw materials, and sieving with a 200-mesh sieve; s3, carrying out segmented sterilization on the sieved powder, firstly drying at 80-90 DEG C for 1 hour, and then sterilizing at 120-130 DEG C for 1.5 hours; and S4, finally, performing vacuum packaging in a sterile environment to obtain the finished product. With galium aparine, paris polyphylla and lysimachia christinae hance as main raw materials, the medicine is good in hemostatic effect, high in safety, simple and feasible in preparation process and suitable for large-scale production.
Owner:罗国友

Compound medicine for treating oral mucositis caused by luconatobutuzumab and preparation method of compound medicine

The invention relates to a compound medicine for treating oral mucositis caused by luconobutuzumab and a preparation method of the compound medicine, and the compound medicine realizes the comprehensive curative effects of resisting inflammation, easing pain and promoting mucosal repair through combination of traditional Chinese medicines and western medicines and synergism of multi-ethnic medicines. The compound medicine is prepared from the following components in parts by weight: 0.1 to 0.5 part of recombinant human epidermal growth factor, 0.5 to 2.0 parts of lidocaine, 0.01 to 0.1 part of vitamin B12, 1.0 to 5.0 parts of astragalus polysaccharide, 0.5 to 3.0 parts of honeysuckle chlorogenic acid, 0.2 to 1.5 parts of glycyrrhizic acid, 0.1 to 1.0 part of crocin, 0.3 to 2.0 parts of saussurea involucrata flavone, 0.2 to 1.8 parts of paris polyphylla saponin and 0.4 to 2.5 parts of sculellaria barbata flavone. The compound provided by the invention is suitable for tumor patients receiving treatment of luconatobutuzumab, is especially suitable for patients suffering from I-III grade oral mucositis, can be used as a hospital preparation or new drug development, and has wide clinical application and market prospects.
Owner:HENAN UNIV OF CHINESE MEDICINE

Antioxidant Compositions and Their Applications

This invention belongs to the field of cosmetics and relates to an antioxidant composition and its application. The composition includes any two of the following: Paris polyphylla extract, Astragalus membranaceus extract, and Poria cocos extract. The antioxidant composition provided by this invention has synergistic antioxidant effects and can be used to prepare skincare products with soothing and repairing effects.
Owner:YUNNAN BAIYAO GRP CO LTD

A bacteriostatic sheng muscle traditional Chinese medicine composition for chronic wounds and application thereof

This invention belongs to the field of medical and nursing care products technology, specifically relating to a traditional Chinese medicine composition for chronic wounds that promotes antibacterial and tissue regeneration, and its application. The raw materials for this composition include Paris polyphylla, dragon's blood, frankincense, myrrh, rhubarb, Phellodendron bark, calamine, pearl powder, Oroxylum indicum, sappanwood, and Rosa laevigata leaves. When this traditional Chinese medicine combination is prepared into a topical ointment and applied to the wound, it possesses potent antibacterial, blood-activating, and tissue-regenerating effects, achieving simultaneous intervention at multiple stages. This improves wound healing and treatment outcomes, addressing issues such as bacterial resistance, insufficient regenerative capacity of modern dressings, and insufficient early-stage antibacterial and anti-inflammatory effects in existing chronic wound treatments. This provides a safe, effective, and economical new treatment option for clinical practice.
Owner:SHANGHAI YANGPU CENT HOSPITAL

Anti-light-damage composition containing rhizoma paridis extract, radix astragali extract and poria cocos extract and application of anti-light-damage composition

The invention discloses an anti-light-damage composition containing a paris polyphylla extract, an astragalus extract and a poria cocos extract and application of the anti-light-damage composition. The composition comprises a paris polyphylla extract, an astragalus extract and a poria cocos extract in a mass ratio of (2-9): (5-32): (2-4). According to the composition, after the paris polyphylla extract, the astragalus extract and the poria cocos extract are combined, the light damage resistance, skin damage repair, skin barrier capacity and skin moisturizing capacity of the composition are remarkably improved through the synergistic effect of the components. The composition is used for preparing cosmetics, and the quality of natural raw material cosmetics is improved.
Owner:YUNNAN BAIYAO GRP CO LTD

Traditional Chinese medicine composition for treating cancer-related fatigue as well as preparation method and application of traditional Chinese medicine composition

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating cancer-related fatigue, which is prepared from astragalus mongholicus, ginseng, dogwood, lucid ganoderma, herba epimedii, medlar, radix ophiopogonis, schisandra chinensis, glutinous rice root, light wheat, oyster, paris polyphylla, turmeric, salvia miltiorrhiza and scorpion. According to the composition, the core pathogenesis of great injury of primordial qi, deficiency of spleen and kidney and internal retention of residual toxins after prostatic cancer (ADT) is subjected to androgen deprivation treatment, the composition is mainly used for reinforcing primordial qi, replenishing qi, strengthening the spleen and tonifying the kidney, is also used for promoting blood circulation and removing toxins, and can remarkably improve fatigue symptoms, life quality and traditional Chinese medicine clinical syndromes of ADT-related cancer-related fatigue patients. The invention further provides a preparation method of the composition and application of the composition in preparation of drugs for treating cancer-related fatigue, and the composition is good in safety and has important clinical application value.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Method for rapidly growing seedling of paris polyphylla var. chinensis

A method for rapid seedling and strong seedling of Paris polyphylla Smith, comprising the following steps: 1) seed selection, 2) pretreatment, 3) after-ripening and germination treatment, 4) young root cultivation, 5) sowing, 6) seedling management. The seedling method is simple, and through the steps of fruit picking, seed selection, pretreatment, after-ripening and germination treatment, young root cultivation, sowing and seedling management, the purpose of cultivating strong Paris polyphylla Smith seedlings is achieved. The planted Paris polyphylla Smith seedlings are strong, the Paris polyphylla Smith seed embryo has a short secondary dormancy time, the germination rate is high, the seedling quality is good, and the seedling cycle is shortened. Compared with the traditional seedling method, the method has low equipment requirements, simple operation steps, is environment-friendly and low in cost, and the cultivated Paris polyphylla Smith seedlings are strong and can be used for large-scale production of Paris polyphylla Smith.
Owner:SANMING AGRI SCI RES INST OF FUJIAN PROVINCE

Bone setting pill for treating bone injury

The invention provides a bonesetting pill for treating bone injury, and relates to the technical field of traditional Chinese medicines. The bonesetting pill for treating bone fracture is prepared from Chinese angelica, poria, Chinese yam, pseudo-ginseng, lotus seed, ground beetle, elecampane, dragon's blood, prepared rehmannia root, safflower, prepared nutgrass galingale rhizome, drynaria rhizome, immature bitter orange, rhizoma dioscoreae nipponicae, paris polyphylla, natural copper processed with vinegar, prepared frankincense, prepared myrrh, ajuga paniculata, cortex moutan, liquorice and borneol. The bone setting pill has the main effects of dissipating blood stasis and stopping bleeding, relieving swelling and pain, promoting reunion of fractured bones and promoting fracture healing, and can effectively treat various fractures, dislocation, traumatic injuries, joint sprain, soft tissue contusion, blood stasis, swelling and pain and the like.
Owner:XICHUAN TANS ORTHOPEDICS & TRAUMATOLOGY HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Application of paris polyphylla extract in inhibiting melanin transfer and cosmetics

ActiveCN116869901BInhibit transferInhibits tyrosinase activityCosmetic preparationsToilet preparationsBiotechnologyMelanin
The application discloses application of paris polyphylla extract in inhibition of melanin transfer and cosmetics, and belongs to the technical field of cosmetics. The paris polyphylla extract contains β-ecdysterone, and the β-ecdysterone can inhibit melanin transfer, thereby achieving a whitening effect. The cosmetics containing the paris polyphylla extract have good whitening effect.
Owner:OSMUN BIOLOGICAL CO LTD

A glycosyltransferase ugt73dy2, its coding gene and application

ActiveCN119614532BFungiBacteriaGlucosidePyran
This invention belongs to the field of natural product biosynthesis technology, specifically relating to a glycosyltransferase UGT73DY2, its encoding gene, and its applications. The diosgenin-3-O-α-L-pyranorhamnetose-(1→4)-[α-L-pyranorhamnetose]-(1→2)-β-D-glucoside and pennosapogenin-3-O-α-L-pyranorhamnetose-(1→4)-[α-L-pyranorhamnetose]-(1→2)-β-D-glucoside synthesized by the glycosyltransferase UGT73DY2 of this invention are key intermediate compounds in the biosynthesis of Paris polyphylla saponins II or VII. These compounds are synthesized in vitro under the catalytic action of glycosyltransferase UGT73DY2, laying the foundation for the industrial production of Paris polyphylla saponins II and VII. Meanwhile, a new Ophiopogon japonicus saponin compound can also be synthesized under the action of glycosyltransferase UGT73DY2, providing a new direction for further research on the application of glycosyltransferase UGT73DY2.
Owner:CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE

A paris polyphylla traditional chinese medicine composition and application thereof in preparation of oral cavity pathogenic bacteria activity inhibitor

The application discloses a traditional Chinese medicine composition of paris polyphylla and application of the traditional Chinese medicine composition in preparation of an oral cavity pathogenic bacterium activity inhibitor. The traditional Chinese medicine extract and extract of the application have the advantages of being natural, efficient, inexpensive, low in toxicity, easy to obtain and the like, and have obvious inhibiting effects on formation of oral cavity pathogenic bacterium Streptococcus mutans biofilm. The biofilm inhibition rate of the paris polyphylla alcohol extract is above 90%, the bacteriostatic rate of the Coptis deltoidea water extract is above 90%, and the bacteriostatic rate and the biofilm inhibition rate of the combination of the two are above 99%. The active ingredient acquisition method of the application is simple, safe and low in cost, and is convenient to popularize and use. The application further provides a natural medicine combination caries prevention method. The combination of drugs can not only enhance the treatment effect, but also serve as an effective prevention means to reduce drug resistance of oral cavity pathogenic bacteria.
Owner:HUNAN UNIV OF SCI & ENG

Five compounds in rhizoma paridis and preparation method and application thereof

The application discloses five new components in aboveground parts of Paris polyphylla, and the structural formulae of the five new components are shown in formula I and formula II: the application also provides a preparation method and application of the five new components. α ,23 α ,27-trihydroxyyamogenin-3 β -yl-O- α -L-rhamnopyranosyl-(1→4)[- α -L-rhamnopyranosyl-(1→2)]- β -D-glucopyranoside (1), 12 α ,23 α ,27-trihydroxyyamogenin-3 β -yl-O- α -L-rhamnopyranosyl-(1→4)- α -L-rhamnopyranosyl-(1→4)- β -D-glucopyranoside (2), 12 α ,23 α ,27-trihydroxyyamogenin-3 β -yl-O- α -L-rhamnopyranosyl-(1→4)- β -D-glucopyranoside (3), (25S)-17 α ,23 α, 27-trihydroxyspirost-5-en-3 β -yl- β -D-glucopyranoside (4), (25S)-3 β ,17 α, 27-trihydroxyspirost-5-en-23- α -yl- β -D-glucopyranoside (5). The compounds 1 and 2 can shorten plasma recalcification time and have hemostatic effect, and the compounds 3-5 can prolong plasma recalcification time and have blood activating effect, and can be developed into new hemostatic / blood activating drugs.
Owner:YUNNAN INST OF MATERIA MEDICA +1

Paris polyphylla seedling raising and germination accelerating box convenient to cultivate

The utility model discloses a paris polyphylla seedling-raising germination accelerating box convenient to cultivate, and relates to the technical field of paris polyphylla cultivation. A box cover is detachably connected to the top of the box body, a supporting plate and a partition plate are oppositely and fixedly installed in the box body, the box body is arranged on the supporting plate, a through groove is formed in the bottom of the partition plate, a plurality of drainage holes communicated with the through groove are formed in the partition plate in a penetrating mode, a spraying assembly is arranged on the box cover relative to the partition plate, and a humidity sensor is arranged at the bottom of the box cover. A control module in signal connection with the humidity sensor and the spraying assembly is arranged on the box body. According to the paris polyphylla seed cultivation box, the process that the box cover needs to be frequently opened to detect the humidity in the box body is avoided through the arrangement of the spraying assembly, the cultivation effect and efficiency of paris polyphylla seeds are improved, meanwhile, seed rot caused by accumulated water is effectively prevented through the design of the through grooves and the drainage holes, and the germination rate is increased.
Owner:YUNNAN MEDICINE MIAO AGRICULTURAL DEVELOPMENT CO LTD

Traditional Chinese medicine patch for external care of postpartum acute mastitis and its preparation method

This invention provides a topical herbal patch for postpartum acute mastitis and its preparation method, belonging to the field of traditional Chinese medicine pharmaceutical technology. The patch is composed of *Paris polyphylla*, *Vaccaria segetalis*, *Uncaria rhynchophylla*, *Bombyx mori*, *Mild Glauber's salt*, processed *Evodia rutaecarpa*, *Citrus aurantium*, *Cirsium japonicum*, *Smilax china*, *Siegesbeckia orientalis*, stir-fried *Melia azedarach*, and licorice. Based on a rigorous formula of principal, assistant, and adjuvant herbs, this patch significantly reduces serum TNF-α, IL-1β, and IL-6 levels in mice with postpartum mastitis, and significantly improves the overall clinical efficacy. It rapidly relieves core symptoms such as breast redness, swelling, pain, and induration, clears milk stasis, and possesses multiple effects including anti-inflammatory, anti-swelling, lactation-promoting, and analgesic properties. This herbal patch is a topical care preparation that acts directly on the affected area of ​​the breast. The drug is absorbed transdermally without gastrointestinal metabolism, and its components do not affect the infant through breast milk. This provides a safe, efficient, and convenient new topical care solution for postpartum acute mastitis.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Novel seedling raising box for polygonatum kingianum

The utility model discloses a novel polygonatum kingianum seedling culture box and belongs to the technical field of polygonatum kingianum seedling culture. The novel polygonatum kingianum seedling culture box comprises a polygonatum kingianum culture box and a temperature control assembly, three sets of supporting plates are installed on the inner wall of the polygonatum kingianum culture box, and each set of supporting plates is connected with a polygonatum kingianum culture frame in a clamped mode. Polygonatum kingianum culture grooves which are arranged at equal intervals are formed in the outer surface of each Polygonatum kingianum culture frame, and by arranging a heating net, a fan, a temperature sensor, a controller and a displayer, people can conveniently check the temperature in the Polygonatum kingianum culture box and conveniently control the temperature in the Polygonatum kingianum culture box. According to the polygonatum kingianum cultivation frame, the polygonatum kingianum can grow in a better environment, people can disassemble and assemble the polygonatum kingianum cultivation frame through the arrangement of a supporting plate, a handle and a limiting rod, people can plant polygonatum kingianum more conveniently, and due to the arrangement of an observation window, tempered glass and an illuminating lamp, the polygonatum kingianum can grow more conveniently. People can conveniently check the growth state of polygonatum kingianum in the polygonatum kingianum incubator at night.
Owner:LANCANG LIANGBAO BIOTECHNOLOGY CO LTD