Systems and methods for imaging an object that are capable of capturing an image or images of the object using an imaging modality, automatically detecting and analyzing the image or images by way of converting the image or images to at least one binary image, and analyzing the at least one binary image to extract and / or segment regions-of-interest (ROIs) from the at least one binary image. The object can be or include an implantation, occlusion, medical device, body lumen, tissue, organ, duct, and / or vessel. The imaging modality can be or include X-ray, CT, MRI, PET, and / or ultrasound, or any combination thereof. Also included are compositions of soft, implantable materials with one or more carbon-based material, nanomaterial, and / or allotrope present in an amount sufficient as an ultrasound contrast agent effective for days, months, or years and which compositions are useful in the automated imaging methods of the invention.