The invention relates to the technical field of
biology, and particularly discloses an
acoustic fluid device and a method for controlling fusion of lipid vesicles through the
acoustic fluid device, the device comprises a glass chamber and piezoelectric ceramics attached to the bottom face of the glass chamber, the piezoelectric ceramics are used for generating ultrasonic
waves, and the glass chamber serves as a
reaction chamber for fusing the lipid vesicles. The method comprises the following steps: determining a
lipid vesicle fusion type, and determining vibration frequency and vibration intensity of required ultrasonic
waves according to the type; and the piezoelectric ceramics generate ultrasonic
waves with required vibration frequency and vibration intensity to act on the glass chamber. According to the invention, the intensity of the sound
stream can be randomly and dynamically adjusted, so that the ultrasonic pulse is utilized to induce the sound
stream to control the fusion of the lipid vesicles in a non-invasive manner. The method has the advantages of no
toxicity, no chemical
reagent residue, simple device, no special requirements on the physical properties of the fluid medium and the lipid membrane, non-contact control, good universality, no requirements on the bioprotein
receptor on the surface of the lipid membrane and the components of the lipid membrane, and good
biocompatibility.