82 results about "Membrane permeabilization" patented technology

The invention discloses a trace water vapor removal device and method based on a membrane permeation technology, and relates to the technical field of online total sulfur analysis, the trace water vapor removal device specifically comprises a membrane drying assembly, the membrane drying assembly comprises a through exchange cavity, a top cover and a bottom cover, the through exchange cavity serves as the center, the top cover is fixed to the top of the through exchange cavity through a bolt, and the bottom cover is fixed to the bottom of the through exchange cavity through a bolt; a bottom cover is fixed at the bottom; an intelligent adjustment and efficient dehydration structure is adopted, the humidity of reaction gas is monitored in real time through a humidity sensor, data are fed back to an external controller, and intelligent linkage adjustment of the opening size of the movable ventilation pipe and the power of the circulating pump is achieved; the dynamic regulation and control mechanism can automatically optimize the flow rate of purge gas and the water-gas exchange area according to the actual humidity change, and it is ensured that the efficient and stable dehydration effect can be achieved under different working conditions.

There is provided a method for producing a product by cells, the method including filtering a cell broth through a porous membrane to obtain a product by the cells, in which the porous membrane has a liquid contact surface having at least any one selected from the group consisting of an opening ratio of 57.5% or less, a pore diameter having a coefficient of variation of 0.5 or less, and a ratio of pore diameter / fiber diameter of 1.3 or less, and the liquid contact surface has at least any one selected from the group consisting of a structural anisotropy of 0.97 or more and 1.03 or less and a ratio of long pore diameter / short pore diameter of 1.8 or less, and a shear stress due to a flow of the cell broth on the liquid contact surface is set to 4.0 N / m2 or less.

The present disclosure provides a carrier peptide fragment with excellent cell membrane permeability. The carrier peptide fragment disclosed herein includes the following amino acid sequence set forth in SEQ ID No.: 1: KKRTLRKSNRKKR, and a lysine residue at a 12th position from an N-terminus of the amino acid sequence is a D-form, and the other amino acid residues are L-forms.

TITLE OF THE INVENTION: DEVICE AND METHOD FOR SEPARING MIXED DIHYDROGEN IN A NATURAL GAS NETWORK A device (35) for separating mixed dihydrogen in a natural gas network, comprising: - an inlet pipe (11) for a gaseous mixture of dihydrogen and natural gas, said inlet pipe including a flow meter (14), - a first outlet (33) for a first gaseous mixture enriched in dihydrogen, - a second outlet (26) for a second gaseous mixture depleted in dihydrogen, said second pipe including a sensor (22) for a dihydrogen concentration, - at least two membrane permeation separation modules (20-1, 20-2, 20-3, 20-4, 20-5) mounted in parallel, producing a retentate discharged through the first outlet and a permeate discharged through the second outlet, connected to the general inlet pipe via a connector (16) comprising a valve (17),and - an automated control system (34) for each valve, determining the number of open valves based on the gas mixture flow rate and the dihydrogen concentration, and controlling the actuation of all or part of the valves according to the determined number. Figure for the abbreviation: Figure 1,

The invention discloses a preparation method and application of a silicon-based functionalized fluorenyl polysubstituted acetylene copolymer and a gas separation membrane thereof. Belongs to the technical field of polymer material and gas separation. The invention provides a new thought for preparation of a high-permeability gas separation membrane material. The preparation method comprises the following steps: carrying out copolymerization on 1-phenyl-2-(7-trimethylsilyl-9, 9-bis (trimethylsilyl-fluorene-2-yl) acetylene and 1-phenyl-2-(7-trimethylsilyl-9, 9-dimethyl-fluorene-2-yl) acetylene under the catalysis of TaCl5-n-Bu4Sn, so as to prepare a copolymer with high molecular weight; the preparation method comprises the following steps of: carrying out film casting on a solution of the nano-silver oxide, and then carrying out desiliconization treatment by using normal hexane / trifluoroacetic acid to obtain a gas separation membrane with the thickness of 100-220 microns, the specific surface area of 298-492 m / g and the total pore volume of 0.134-0.299 cm / g. The prepared separation membrane has the advantages that the COpermeability is up to 36,900 Barrer, the Opermeability is 19,800 Barrer, the thermal decomposition temperature exceeds 420 DEG C, the separation membrane can be used for separating gases such as COO, ON and the like, the preparation process is simple and convenient, and the industrial potential is realized.

This invention discloses an acid and alkali resistant polyamide membrane and its preparation method. The method is as follows: S1: Immerse the ultrafiltration base membrane in an aqueous sodium hydroxide solution for soaking and then set aside; S2: Treat the base membrane with a mixed aqueous solution of polyamine and aziridine crosslinking agent; S3: Wet the base membrane in an organic phase solution of polyacrylamide monomer to obtain a polyamide composite membrane; S4: Immerse the prepared polyamide composite membrane in an alcoholic solution of hydroxymethyl crosslinking agent, then dry it in a forced-air drying oven, and after washing with water, obtain the acid and alkali resistant polyamide membrane. This application uses two crosslinking agents, aziridine and hydroxymethyl, which can undergo specific crosslinking reactions with the carboxyl groups inside the polyamide membrane, to directly perform dual crosslinking modification on the membrane interior and surface, without introducing other polymer materials to avoid excessive increase in membrane permeation resistance. The polyamide membrane prepared by this method has both good acid and alkali resistance and water permeability.

Processes and systems are provided for treating the tail gas stream of a sulfur recovery plant. The process comprising the steps of treating the compressed tail gas stream in a pre-treatment unit to remove the impurities; separating the dry stream in a first stage membrane unit, the first stage membrane unit comprises a membrane selective to carbon dioxide and hydrogen; reducing a temperature of the cryogenic feed in a cryogenic cooler to produce a cryogenic stream; separating the cryogenic feed in a knock-drum to produce a liquid carbon dioxide and membrane feed; separating the membrane feed in a second stage membrane unit to produce a rubbery membrane permeate and a rubbery membrane retentate, where the second stage membrane unit comprises a membrane selective to carbon dioxide over hydrogen; and treating the rubbery membrane retentate in a hydrogen recovery process to produce a hydrogen product stream and a carbon dioxide lean stream.

The present invention provides a spiral membrane element suitable for suppressing a decrease in a permeation rate (or a permeation flux) of a permeated fluid from a separation membrane. A spiral membrane element of the present invention includes: a central tube; a membrane leaf that has a separation membrane and a permeation spacer and is wound around the central tube; and a flow passage spacer that is connected to the permeation spacer and is wound around the central tube on a side closer to the central tube than the membrane leaf is. A pressure loss of the flow passage spacer measured by a predetermined test is smaller than a pressure loss of the permeation spacer.

The purpose of this invention is to provide a method for preparing a mixed matrix membrane for CO2 / CH4 separation, belonging to the field of gas separation technology. This method prepares a mixed matrix membrane by incorporating Cu(Qc)2 into a 6FDA-DAM matrix, which improves the limiting effect between the permeability and selectivity of the 6FDA-DAM membrane and greatly enhances the CO2 permeability coefficient and CO2 / CH4 selectivity.

This invention relates to a PDMS / PAN composite membrane based on a chemically modified PAN membrane, which is composed of a PAN substrate membrane sequentially modified with NaOH and GMA and grafted with methacrylate-functionalized PDMS. The invention also relates to a method for preparing the above membrane, which involves sequentially chemically modifying the PAN substrate membrane with NaOH and GMA in two steps to introduce acrylate double bonds onto the surface of the PAN membrane, followed by further photopolymerization grafting of a PDMS selective layer to prepare the PDMS / PAN composite membrane. This improves the adhesion of the PDMS selective layer, effectively mitigating cracking and delamination phenomena in practical applications of the PDMS / PAN composite membrane. Simultaneously, the membrane's performance in pervaporation and ethanol separation is significantly enhanced, greatly improving the application prospects of PDMS membranes in actual pervaporation processes.

The application discloses a method for improving the flux and hydrophobicity of a uniform pore membrane by selective fluorination, comprising the following steps: immersing a uniform pore membrane with a pore size of 5-100 nm and containing carboxyl functional groups into a reaction solution, wherein the reaction solution comprises a silver salt catalyst with a mass concentration in the range of 0.1-3.5 wt%, a fluorination reagent with a mass concentration in the range of 0.15-5.5 wt%, an oxidizing agent with a mass concentration in the range of 0.05-7.5 wt%, a co-catalyst with a mass concentration in the range of 0.15-5.5 wt%, water and an organic solvent with a mass concentration in the range of 5-65 wt%; reacting at 4-60 DEG C for 15 min-72 h, taking out the membrane, and then sequentially cleaning the membrane with ethanol and deionized water to obtain a uniform pore membrane with good membrane flux and hydrophobicity. The application improves the permeability and separation selectivity of the uniform pore membrane by selective fluorination, and the uniform pore membrane is not damaged, and the method has universality.

Provided is a membrane permeation promoter that promotes permeation of a conjugate of a target substance and a transmembrane peptide into a lipid bilayer membrane, the membrane permeation promoter containing a flavonoid. Also provided are a membrane permeation promoting method and intracellular delivery method using the membrane permeation promoter, and an intracellular delivery kit comprising the membrane permeation promoter.

Installation and method for treating a feed gas stream (1) comprising carbon dioxide and methane by membrane permeation, said feed gas stream comprising at least 90 mol% carbon dioxide and between 0.5 and 10 mol% methane, and said apparatus comprising a compressor (8) configured to compress the feed gas stream (1) to a pressure between 2 barg and 16 barg, a membrane separation unit (3) configured to receive the feed gas stream (1) and to provide a permeate (2) and a retentate (4), a feed line (5) for the feed gas stream (1) to the membrane separation unit (3), and a retrieval line (9) for the retentate (4) configured to send the retentate (4) to a biogas production and / or storage unit. Abbreviated figure: Fig. 1

We provide novel, specific cytotoxic drug therapies with minimal side effects. [Solution] A composition for a membrane-permeable complex for transport across a lipid membrane is provided, comprising one or more molecular induction system (MGS) peptides and a cytotoxic agent. A method for treating cancer is also provided, comprising administering this composition to a cancer patient.

Processes and systems arc provided for treating the tail gas stream of a sulfur recovery plant. The process comprising the steps of treating the compressed tail gas stream in a pre-treatment unit to remove the impurities; separating the dry stream in a first stage membrane unit, the first stage membrane unit comprises a membrane selective to carbon dioxide and hydrogen; reducing a temperature of the cryogenic feed in a cryogenic cooler to produce a cryogenic stream; separating the cryogenic feed in a knock-drum to produce a liquid carbon dioxide and membrane feed; separating the membrane feed in a second stage membrane unit to produce a rubbery membrane permeate and a rubbery membrane retentate, where the second stage membrane unit comprises a membrane selective to carbon dioxide over hydrogen; and treating the rubbery membrane retentate in a hydrogen recovery process to produce a hydrogen product stream and a carbon dioxide lean stream.

A novel reverse osmosis or nanofiltration (RO / NF) system is developed that utilizes a uniquely configured membrane permeate flow path within the system to detect and respond to the onset of fouling, generating time-sensitive data. Membrane performance data under real-time operating conditions is then used to rapidly detect membrane fouling, fouling rate, and fouling causes. Subsequently, controller-based system-generated actions are employed to stop fouling and recover from or slow it down. Furthermore, operator intervention steps are anticipated, planned, and scheduled, if necessary, to restore optimal system operating conditions. The end result is a novel, energy-efficient, and advanced (machine learning) reverse osmosis system for brackish water desalination and fouling management.

The utility model discloses a methanol-water concentration proportioning system based on membrane permeation, which relates to the technical field of direct methanol fuel cells, and comprises a diaphragm liquid mixing tank, the diaphragm liquid mixing tank comprises a first end plate, a proton exchange membrane and a second end plate, the side surface of the first end plate is provided with a methanol cavity, the side surface of the second end plate is provided with a water mixing cavity, and the proton exchange membrane is arranged in the water mixing cavity. The proton exchange membrane is clamped between the first end plate and the second end plate and divides the methanol cavity and the water mixing cavity into two sides, and methanol in the methanol cavity can permeate into the water mixing cavity through the proton exchange membrane. According to the mechanism that the proton exchange membrane allows methanol molecules to diffuse due to a hydrophilic channel, so that the methanol permeability is high, the interior of the diaphragm liquid mixing tank is divided into the methanol cavity and the water mixing cavity through the proton exchange membrane, and part of methanol on the side of the methanol cavity permeates into the water mixing cavity through the proton exchange membrane; the methanol water concentration required by the direct methanol fuel cell is directly prepared, the operation is simple, and the methanol water concentration is easy to control.

The invention relates to the technical field of separation, and provides a hollow fiber membrane negative pressure gas production process. According to the process, feed gas is fed into an inlet of a hollow fiber membrane separator by power equipment, and the feed gas flows inside or outside hollow fiber membrane filaments; components with relatively high permeability permeate to the permeation side through the membrane and are continuously pumped and discharged by a vacuum pump communicated with a gas outlet of the permeation side so as to reduce the absolute pressure of the permeation side and stabilize the pressure difference; and components which are not easy to permeate are collected in the membrane channel and are discharged from a tail gas side outlet. The negative pressure is applied to the permeation side to reduce the partial pressure of the permeation side and amplify the effective transmembrane partial pressure difference, so that higher permeation driving force can be obtained under lower air inlet pressure, and the energy consumption of air inlet power equipment can be reduced while the separation performance is ensured. The process is compact in structure and easy to integrate, can be matched with dust removal, dehydration, cooling and other pretreatment units, and is suitable for large-scale gas separation and other industrial scenes.

This invention discloses a method for solid-liquid separation and resource recovery of mineral slurry, comprising the following steps: S1, chemical sedimentation pretreatment of mineral slurry: adding a sedimentation filter aid containing a main coagulant and an auxiliary flocculant to the mineral slurry, stirring and reacting, and then allowing it to settle to separate the upper clarified water and the bottom high-concentration concentrated mineral slurry; S2, deep solid-liquid separation using membrane technology: sending the concentrated mineral slurry into a dynamic rotating membrane separator for solid-liquid separation to obtain membrane permeate and solid filter media; S3, water resource recovery: classifying and reusing the upper clarified water and membrane permeate for mineral processing; S4, solid resource recovery: utilizing the solid filter media according to its composition, including as raw material for building materials, regrinding and reprocessing, or hydrometallurgy. This invention achieves efficient solid-liquid separation and synergistic recovery of water and solid resources through a combination of chemical sedimentation and dynamic membrane separation, offering advantages such as good separation effect, high water resource utilization rate, high solid resource recovery value, and low operating cost.

The invention relates to a method for providing a water-soluble adduct and an ibuprofen adduct, wherein the membrane permeability of the adduct is improved and the classification according to the Biopharmaceutics Classification System is influenced.

The invention relates to a target gas separation and purification system and method based on single pressurization and double reflux, the system comprises a first-stage membrane, an interstage compressor, a second-stage first-section membrane, a valve, a second-stage second-section membrane, a first reflux pipeline and a second reflux pipeline which are sequentially connected in series, the first-stage membrane carries out first-stage separation on first gas, the first gas at least comprises raw material gas, and the second gas at least comprises raw material gas; the interstage compressor pressurizes second gas, the second gas at least comprises first-stage membrane permeable gas, the second-stage first-stage membrane performs second-stage first-stage separation on the pressurized second gas, the valve adjusts the flow of second-stage first-stage membrane retentate gas, the second-stage second-stage membrane performs second-stage second-stage separation on the second-stage first-stage membrane retentate gas, and the second-stage first-stage membrane performs second-stage second-stage separation on the second-stage first-stage membrane retentate gas. The first backflow pipeline enables second-stage second-section membrane permeation gas to flow back to the inlet of the interstage compressor, the second backflow pipeline enables second-stage second-section membrane permeation residual gas to flow back to the inlet of the first-stage membrane, single-pressurization double-backflow is achieved, the concentration multiple and the yield are greatly improved, pressurization energy consumption is reduced, the backflow proportion is automatically adjusted through a valve, and the separation and purification efficiency is improved.

Ion exchange membranes and methods for forming the membranes are described. The ion exchange membrane may be incorporated into a redox flow battery. The membrane may exhibit a desirable high conductivity of ions (e.g., protons or hydroxide ions) as well as stability and durability in redox flow battery environments while also exhibiting low permeability to redox couple species. The film is formed according to a polyphosphoric acid forming technique and subjected to densification and heat treatment.

The invention provides a method for separating trace organic matters in water based on non-isothermal pervaporation, which comprises the following steps: additionally arranging a conductive porous support membrane (carbon nanotube membrane) on one side of pervaporation separation membrane penetrating fluid, and electrically heating the support membrane part; the temperature of the penetrating fluid side of the pervaporation separation membrane is higher than that of the raw material liquid side of the pervaporation separation membrane, so that the micro-temperature gradient of the pervaporation separation membrane is formed. According to the method, the temperature trade-off effect influencing flux and separation factors is eliminated in a mode of actively creating temperature gradient (non-isothermal) in a microenvironment, high selectivity and good treatment capacity can be achieved at the same time, and the method has a remarkable effect on improvement of pervaporation performance.

The present invention discloses a method for capturing an RNA in situ higher-order structure and interaction. The method includes: fixing protein-mediated RNA-RNA interaction in cell or tissue; performing membrane permeabilization while keeping the cell intact; degrading free RNA; labeling the 3′ end of the RNA with pCp-biotin and performing proximal ligation in situ; purifying the chimeric RNA containing the pCp-biotin after the cell is digested; constructing the strand-specific library; and performing high-throughput sequencing. In the present invention, under the condition of not destroying the cell structure and keeping the integrity of cell, treat the intracellular RNA in situ, and capture RNA intra- and intermolecular interactions in a physiological state; the 3′ end of the RNA is labeled with the pCp-biotin, and in situ ligation is performed under non-denaturing conditions, thereby greatly improving the labeling efficiency and reducing intermolecular specific ligation; and the chimeric RNA labeled with C-biotin is enriched by C1 magnetic beads, so that the fraction of effective sequencing data is increased, and the sequencing cost is reduced.

A method for harvesting energy through pressure retarded osmosis includes identifying and pumping a low salinity feed stream and a high salinity feed stream from upstream water sources to opposite ends of a semi-permeable membrane housing where the low salinity feed stream permeates through the semi-permeable membrane to the high salinity feed stream to pressurize and dilute it. The diluted stream rotates a turbine to generate electricity and produce a depressurized mid-salinity fluid. A system for harvesting energy through pressure retarded osmosis has a first and second upstream water source pumped through low and high salinity feed lines to opposite ends of a semi-permeable membrane housing including a container, a semi-permeable membrane, a low salinity side of the housing, and a high salinity housing. The system also has a low salinity exit line, a pressurized mid-salinity exit line, a turbine, a generator, and a depressurized mid-salinity exit line.

This invention relates to a self-optimization method for acetylene purification operating parameters based on the coupling of membrane permeation characteristics and operating conditions, belonging to the field of gas separation technology. The method includes: obtaining the functional relationship between the permeability coefficient of a single-component gas and pressure and temperature; establishing a response model of impurity removal rate and acetylene loss rate with transmembrane pressure difference and feed flow rate, introducing correction terms for adsorption saturation and diffusion mechanisms; defining a multi-objective function and constraints including product purity, impurity reduction, acetylene loss rate, and energy consumption; using an iterative optimization algorithm to obtain the optimal operating parameters; distributing the optimal parameters to the control system, and periodically correcting the model parameters based on online analysis feedback. This invention also integrates operational limit assessment and membrane performance degradation diagnosis functions. This invention transforms the actual permeation characteristics of membrane materials into executable operating parameters, reducing acetylene loss and energy consumption while ensuring high-purity acetylene, providing a quantitative design basis for the engineering scale-up of acetylene membrane separation and purification.

The present application relates to a kind of preparation high-flux polyamide composite membrane method, belong to nanocomposite membrane design and preparation field.It includes porous support layer and separation layer, separation layer is formed by the interfacial polymerization of aqueous phase amine monomer and organic phase acyl chloride monomer, while adding sodium tetraphenylborate in aqueous phase, adding organic potassium salt in organic phase, utilize sodium tetraphenylborate and organic potassium salt at interface with polyamide layer Synchronous formation potassium tetraphenylborate nanoparticles, then utilize acetone to dissolve nanoparticle, finally form with non-through cavity structure in the inside and surface of separation layer, obtain with high-flux and high salt retention rate polyamide composite membrane.This method nanoparticle is formed synchronously with polyamide separation layer, the cavity structure formed finally can be evenly distributed in the inside of entire polyamide separation layer, and the effective thickness of polyamide separation layer is thinned.Polyamide composite membrane with cavity structure can be increased by more than one time permeation flux.

Processes and systems for recovering hydrogen include feeding a gas stream, comprising hydrogen and additional gases, to a pressure swing adsorption (PSA) system and feeding a membrane permeate stream comprising hydrogen to the PSA system. In the PSA system, a portion of the hydrogen is separated from the additional gases to recover a hydrogen product stream and a PSA tail gas stream comprising unseparated hydrogen and the additional gases. The PSA tail gas stream is fed to a membrane separation unit for separating hydrogen from the additional gases and to recover (i) the membrane permeate stream comprising hydrogen fed to the PSA system and (ii) a membrane tail gas stream comprising the additional gases. Processes and systems herein may additionally include a refrigeration system for partially condensing one or both of the feed gas stream and the PSA tail gas stream, enhancing the efficiency of the membrane separation unit.

This invention provides a method for calculating the transmembrane permeation free energy of small molecules and a method for establishing a dataset, belonging to the field of free energy calculation technology. The method for calculating the transmembrane permeation free energy of small molecules uses a molecular bond network algorithm to coarsely parameterize small molecules, constructs a water-membrane system, and utilizes molecular dynamics simulation software to perform tensile dynamics simulation and umbrella sampling simulation, thereby obtaining the free energy change curve of the compound's transmembrane permeation process and the water-membrane distribution free energy. This not only significantly saves experimental time but also generates a large batch of high-quality transmembrane permeation capacity data. The method for establishing the small molecule transmembrane permeation free energy dataset uses chemical feature space to screen molecules, making the dataset widely applicable and highly representative. Drug transmembrane free energy prediction models trained using this dataset can more accurately predict the transmembrane capacity of drugs, providing a scientific basis for drug development.