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System and method for ultrasonic measuring of particle properties

a particle and ultrasonic technology, applied in the field of measuring and detecting the properties of particles, can solve the problems of high backscatter levels of this volume, and achieve the effect of high backscatter levels and high levels of acoustic energy

Active Publication Date: 2009-06-09
PRODYNE CORP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention is about devices, systems, and methods for measuring and detecting properties of particles in suspension using ultrasonic technology. The invention uses narrow-band acoustic interrogating energy to generate high levels of acoustic energy in a small volume and in a narrow frequency range. This produces high levels of backscatter from the particles, which can be measured to determine particle velocities and size, as well as the concentration of particles in the suspension. The invention also includes processing of the receiving signal and determining properties such as velocities and size of particles from a high precision power spectrum of the signal. Additionally, the invention includes back wall reflection calibration for self-checking of the system.

Problems solved by technology

This may produce high levels of backscatter from this volume.

Method used

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Embodiment Construction

[0029]In the following description, various aspects of the present invention will be described. For purposes of explanation, specific configurations and details are set forth in order to provide a thorough understanding of the present invention. However, it will also be apparent to one skilled in the art that the present invention may be practiced without the specific details presented herein. Furthermore, well-known features may be omitted or simplified in order not to obscure the present invention. Various examples are given throughout this description. These are merely descriptions of specific embodiments of the invention. The scope of the invention is not limited to the examples given.

[0030]Unless specifically stated otherwise, as apparent from the following discussions, it is appreciated that throughout the specification, discussions utilizing terms such as “processing,”“computing,”“calculating,”“determining,”“deriving” or the like, refer to the action and / or processes of a pro...

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Abstract

Devices, systems and methods for measuring and detecting properties of a variety of particles or cells in suspension. Properties, such as, for example, velocity of particles, concentration and / or size may be measured according to the methods of the invention. Acoustic energy may be introduced to a focal zone and narrow band interrogating signals may be used. The acoustic energy may cause movement or streaming of the fluid or suspension. The acoustic streaming may allow a Doppler effect measurement without any other source of velocity.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This Application claims the benefit of the U.S. Provisional Application U.S. Ser. No. 60 / 627,927, filed on Nov. 15, 2004 which is fully incorporated herein.FIELD OF THE INVENTION[0002]The present invention relates to measuring and detecting of properties of particles for example in suspension, for example by using ultrasonic techniques.BACKGROUND OF THE INVENTION[0003]Ultrasonic methods and systems may be used to measure the concentration and other properties of suspended particles or other materials, including, for example, biologic materials. For example, there is a need to measure concentration of human islets in preparations for human transplantation. These measurements can be combined with separate measures of the viability of the islets to determine the number of viable and dead cells in a preparation. There is also a need for systems that can measure properties of small particles on a nanoscale.SUMMARY OF THE INVENTION[0004]Embodim...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): G01N11/10
CPCG01N15/02G01N29/032G01N29/11G01N29/222G01N29/348G01N29/46G01N2291/017G01N2291/0224G01N2291/02416G01N2291/02809G01N2291/02836G01N2291/044
Inventor AFRICK, STEVEN A.COLTON, CLARK K.
Owner PRODYNE CORP
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