The present invention relates to a polyherbal tablet formulation for the treatment of
gouty arthritis and
hyperuricemia. The formulation comprises
ethanol extracts of six
medicinal plants, each contributing specific bioactive compounds with
xanthine oxidase (XO) inhibitory,
antioxidant, and anti-inflammatory properties. The tablet includes Colchicum autumnale (50mg),
Berberis vulgaris (100 mg),
Apium graveolens (25 mg),
Capparis decidua (25 mg), Fagonia cretica (25 mg), and Trachyspermum ammi (75 mg), combined with a
liquid glucose solution to form a 300 mg tablet. The manufacturing method involves
ethanol extraction of each
plant (70%
ethanol, 72 hours),
filtration,
solvent evaporation under reduced pressure, blending of equal amounts of the extracts with glucose, and
drying at 50°C for 12 hours. The resulting formulation demonstrates enhanced therapeutic
efficacy in reducing
uric acid levels and alleviating joint
inflammation, supported by
in vitro and
in vivo pharmacological assays.