59 results about "Biosensor device" patented technology

Devices, systems, methods, and software for providing remote medical diagnosis and therapy to a subject comprising: a module for conducting telecommunications with a telemedicalist; a module for applying a diagnostic or a therapeutic analysis; an apparatus for dispensing one or more medical items from an inventory of medical items, the inventory of medical items risk profiled to a subject, a population, a venue, or a situation; and optionally, a biosensor apparatus.

A real-time drug interaction alert system using AI-powered analytics, consisting of: a wearable or implantable biosensor device configured to continuously measure physiological parameters of a subject, including at least heart rate, blood pressure, blood oxygen saturation, skin temperature, and biomarkers related to liver and kidney function; a communication module integrated into the device that can securely transmit physiological data to a cloud-based analysis engine via wireless protocols such as Bluetooth Low Energy (BLE), Wi-Fi, or LTE-M; a cloud-hosted artificial intelligence (AI) inference engine configured to perform multimodal drug-drug interaction risk analysis, the engine comprising at least a convolutional neural network (CNN) for time-series analysis of biosignal patterns, a natural language processing (NLP) module for extracting drug information from structured and unstructured medical sources, and a Bayesian reasoning module for modeling probabilistic risk interactions between drugs and patient-specific variables; a pharmaceutical input interface for capturing medication data by at least one of the following methods: manual entry, optical character recognition (OCR) of the packaging, or near field communication (NFC) scanning of embedded tags; an alert dissemination module configured to trigger multi-channel alerts, including haptic signals via the wearable device, audiovisual notifications via a paired smart device, and the secure transmission of interaction reports to designated healthcare professionals based on severity thresholds.

A semiconductor biosensor diagnostic system is provided. The semiconductor biosensor diagnostic system includes a diagnostic cartridge and a cartridge diagnostic base. The diagnostic cartridge includes a biosensor device and a fluid-guide body over the biosensor device. The fluid-guide body includes a first pumping opening, a second pumping opening, a buffer reservoir, a sample reservoir, and a plurality of channels configured to provide a first loop including the first pumping opening and the buffer reservoir, and a second loop including the second pumping opening and the sample reservoir. The first loop and the second loop sharing a common channel passing through the biosensor device. The cartridge diagnostic base includes a plurality of micro pumps coupled to the first pumping opening and the second pumping opening, and a sensing structure configured to receive a sensing information from the biosensor device.

An improved wearable biosensor device having emergent properties such as extended wear life, elimination or significant reduction of warm-up time, a user-friendly insertion process that ensures secure skin-locking immediately post-insertion, enhanced durability of microneedles against breakage, superior user experience and comfort during wear, and improved scalable manufacturability. Together, these innovations not only elevate the sensor's overall performance but also its accuracy, functionality, and reliability. This novel design and functionality guarantees that the wearable biosensor device is more efficient, provides a better experience for users and establishes a new benchmark in the industry.

The present invention provides a non-invasive, portable, multimodal wearable sweat sensor device, belonging to the technical field of wearable biosensor devices. ZrCl4, a monobasic acid modifier, and terephthalic acid are dissolved in an organic solvent, followed by a hydrothermal reaction. After the hydrothermal reaction, the white precipitate is collected and treated in a mixed solution of hydrochloric acid and DMF, centrifuged, washed, and dried to obtain a metal organic framework (MOF) carrier. The MOF carrier, GOx, and HRP are added to a buffer solution, stirred, centrifuged, and washed to obtain an enzyme-encapsulated metal organic framework (MOF) material. The enzyme-encapsulated MOF material is fabricated into a detection point, which, together with a skin adhesion layer, a paper-based microfluidic layer, and an encapsulation layer, forms a non-invasive, portable, multimodal wearable sweat sensor device. The sensor device can be directly integrated with the skin surface to continuously and in real time quantify sweat loss and provide quantitative data on glucose in sweat.

To provide a system capable of maintaining the health of an aged person and reducing the burden of caring for the aged person.SOLUTION: A system comprising: biological sensor means for measuring a vital sign; communication means for transmitting measured vital sign data to a communication terminal of a user; communication terminal means for relaying the vital sign data to a server; analysis means for analyzing the vital sign data in real time in the server; generation means for generating an individual health assistance menu based on a result of the analysis; and transmission means for transmitting the health assistance menu to the communication terminal.SELECTED DRAWING: Figure 1

Smart Food Container Lid Biosensor Device

A biosensor cartridge is disclosed. The biosensor cartridge according to one aspect of the present invention is a biosensor cartridge that detects a biological substance and generates an electrochemiluminescence signal, and includes an electrode portion including a plurality of electrodes, and a signal chamber that is an overall space provided on the electrode portion, and a dividing portion disposed on the electrode portion so as to divide the signal chamber into N reaction chambers surrounding the signal chamber. The electrode portion includes a first electrode at least a part of which is disposed in the reaction chamber, a second electrode disposed in the signal chamber, and N connection electrodes disposed so as to electrically link the chemical reaction in the reaction chamber and the electrochemiluminescence signal generated in the signal chamber.

A board-end connector and a biosensor device comprising the same are disclosed. The board-end connector includes an insulator having a recess and a plurality of conductive members fixed to the insulator. Each conductive member includes a first elastic arm and a second elastic arm that are electrically connected to each other and correspondingly contact two electronic devices. A first electrical contact portion disposed at an upper end of the first elastic arm is exposed at an upper portion of the insulator. The recess is configured to accommodate one electronic device. A second electrical contact portion disposed at an upper end of the second elastic arm is exposed within the recess.

Smart AI-Integrated Water Quality Biosensor device

Methods, systems and devices for detecting the presence of a pathogen, for example, a virus (e.g., SARS-COV-2), or its molecular components, in health care-related samples and / or environmental samples are disclosed. An example system for improving detection of a pathogen includes biosensor device comprising a detection chip and at least one probe that specifically recognizes a pathogen, where the detection chip comprises a graphene field-effect transistor (FET) chip and the probe, which comprises an aptamer, specifically binds to a DNA, RNA, or protein associated with the pathogen.

The present disclosure relates to carbon-based biosensors and biosensor systems. The disclosure further relates to methods of rapidly detecting a target material in a biological sample using the biosensor and biosensor systems described herein to characterize a pathogen's antigen profile and / or a subject's immune response to pathogen exposure, providing an innovative point-of-care biosensor device.

The invention discloses a micro-fluidic chip integrated with an optical modulation cavity and a biological sensing device, and relates to the technical field of optical detection. The micro-fluidic chip comprises a substrate layer, an optical structure layer and a detection pool layer which are sequentially arranged from bottom to top, the optical structure layer is provided with an incident modulation cavity, an emergent modulation cavity, an incident optical fiber groove, an emergent optical fiber groove and a sensing interface, and the incident modulation cavity and the emergent modulation cavity are both micron-sized polyhedral integrated cavities. The detection pool layer is provided with a lofting structure suitable for placing a sample to be detected, the incident optical fiber groove is suitable for inserting an incident optical fiber, and the emergent optical fiber groove is suitable for inserting an emergent optical fiber; incident light introduced by the incident optical fiber is subjected to first modulation through the incident modulation cavity, then reaches the sensing interface and acts on a sample to be detected, and is reflected into emergent light; the emergent light is subjected to second modulation through the emergent modulation cavity and then is led out through the emergent optical fiber. The micro-fluidic chip can realize a biosensing function, is high in sensitivity and low in sample and reagent consumption, and can be easily combined with a microscope and the like.

A biosensor device is provided. The biosensor includes an amplifying bipolar junction transistor (BJT) and a sensing BJT defining a sensing trench. The sensing BJT and the amplifying BJT are coupled to form a Sziklai pair with an emitter of the sensing BJT connected to a collector of the amplifying BJT and a collector of the sensing BJT connected to a base of the amplifying BJT.

Plasmonic biosensor device comprising a first and second electrode, a charge carrier tunnelling junction for providing charge carriers for generating electroluminescent light emission, that is in electrical connection with the first and second electrodes for application of a voltage potential difference. The second electrode comprises or forms a plasmonic structure including a plurality of optical nanoantennas or a plurality of electrically interconnected optical nanoantennas configured to generate plasmons and light emission via the charge carriers provided by charge carrier tunneling in the charge carrier tunnelling junction. The plurality of optical nanoantennas extend thereon.

A computing device and a method of operating a computing device, implementable as a computer program product, the method including first operating a first transceiver in the computing device to collect a first biosensor device data element into a storage and processing location; second operating the first or a second transceiver to collect a second biosensor device data element into the storage and processing location; applying, in the storage and processing location, machine learning model inferencing over at least the first biosensor device data element and the second biosensor device data element to derive a user condition indication for a biosensor device user; and on detecting, in the user condition indication, a predictive value above a threshold indicating a user condition requiring notification, emitting a message at an output of the computing device, where the user condition requiring notification includes one or both of a physical and mental condition.

Mechanical biosensor apparatus used in the detection of stem cells

The invention relates to a biosensor device for sensing an analyte over a certain period of time using particle motion, the biosensor device having a surface and particles, wherein the particles and / or the surface are functionalized, and wherein the biosensor device has a first state in which the particles are associated with the surface and a second state in which the particles are not associated with the surface, and wherein the transition between the first and second state depends on the presence, absence and / or concentration of the analyte, whereby the motion characteristics of the particles change depending on the presence, absence and / or concentration of the analyte, and wherein the properties of the particles and the surface are chosen such that in the second state the particles are in the vicinity of the surface such that the biosensor is able to measure changes in the spatial coordinate parameters of the particles relative to the surface, wherein the particles are not conjugated to the surface.

Biosensor devices and methods of forming the same are provided. A cavity is formed in a substrate and is configured to receive one or more charged molecules. A transistor is formed in the substrate and includes a source region, a drain region, and a channel region that are spatially separated from the cavity in a lateral direction. A gate of the transistor is disposed below the cavity and extends between the cavity and the source, drain, and channel regions. A voltage potential of the gate is based on a number of the charged molecules in the cavity.

One disclosed example method includes receiving sensor data from a biosensor; determining an event using a first analysis based on the sensor data, the first analysis having a first power cost; determining to perform a second analysis based on the event; in response to determining to perform the second analysis, performing the second analysis based on the sensor data, the second analysis having a second power cost greater than the first power cost; and wirelessly transmitting results of the second analysis to a remote device.

In described examples, a biosensor device has a porous membrane with a test region that contains a test analyte. A sensor die has an ion sensing field effect transistor (ISFET) with an ion sensitive gate element located in an active sensor surface of the sensor die. The active sensor surface is in contact with the porous membrane test region. A controller is coupled to the ISFET and an interface module is coupled to the controller to provide a human readable test result.

The present invention relates to a biosensor device for sensing an analyte over a period of time using particle motion, the biosensor device having a surface and a particle, wherein the particle and / or the surface are functionalized, and wherein the biosensor device has a first state in which the particle is associated with the surface and a second state in which the particle is not associated with the surface, and wherein switching between the first and second states depends on the presence, absence and / or concentration of the analyte, whereby motion characteristics of the particle change depending on the presence, absence and / or concentration of the analyte, thereby allowing sensing of the analyte by measuring changes in a spatial coordinate parameter of the particle relative to the surface, and wherein the properties of the particle and surface are selected such that in the second state the particle is within the vicinity of the surface such that the biosensor is able to measure changes in a spatial coordinate parameter of the particle relative to the surface, preferably wherein the distance between the particle and the surface in the second state is within the range of 5 nm to 10 μm and wherein the particle is not conjugated to the surface.

A multi-sensor optical biosensor system to determine one or more health parameters of a user, such as the user's blood pressure. The system includes a multi-sensor wearable device communicatively connected to a user compute device, which may be in communication with a remote compute device. The multi-sensor wearable device could include optical devices to generate a photoplethysmogram ("PPG") signal that is transmitted to the user compute device. In some cases, the multi-sensor wearable device may be configured to select a PPG channel to transmit to the user's compute device from a plurality of PPG channels based on one or more selection parameters.

A fluid device and a method of preventing exudation of a spacer material in the fluid device are described herein. The fluid device includes a bulk acoustic resonator structure that defines at least one surface area region on which a functionalized material is disposed and the resonator structure includes a repulsion region. The fluid device further includes a spacer material that is disposed on the resonator structure and is disposed away from the at least one surface area region. The repulsion region is configured to prevent the spacer material from extending into the at least one surface area region. Additionally, an electronic board may be operatively attached to the resonator structure and the spacer material may be disposed in a gap between the electronic board and the resonator structure to electrically isolate electrical contacts and form a fluid channel.

The invention relates to the field of ecology, and more particularly to analytical biosensor devices. The claimed device can be used for detecting (determining) the level of contamination of water with biodegradable organic compounds by measuring the biochemical oxygen demand of samples of water of various origins, including fresh surface water, subsurface water (groundwater), drinking water, wastewater and purified wastewater. An analytical biosensor device for detecting the level of contamination of water with biodegradable organic compounds comprises: a measuring cuvette (3) containing a buffer solution; a magnetic stirrer (4); and a biosensor system comprising an oxygen electrode (1) configured for connection to an appliance for recording the biosensor system response, and, arranged on said oxygen electrode (1), a receptor element (2) comprising an association of microorganisms immobilized on a carrier, the analytical biosensor device being characterized in that the microorganisms used are Paracoccus yeei VKM B-3302, Pseudomonas veronii VKM В-3835 and Rhodococcus fascians VKM Ас-2996 in a mass ratio of 1:1:1, which are immobilized on a nitrocellulsoe membrane and are coated on top with a chitosan solution that forms a hydrogel after drying. The technical result of the invention is that of increasing the upper limit of the range of detectable biochemical oxygen demand (BOD) values to 200 mg / dm3, enhancing the operational stability of the biosensor system response, as well as increasing the stable operational lifetime of the biosensor system.

A photonic biosensor apparatus comprises a sample addition zone in fluid communication with a wicking zone and a sample detection zone, at least one optical input port disposed within the sample detection zone, wherein the optical input port is configured to optically couple to a light source, at least one optical output port disposed within the sample detection zone, wherein the optical output port is configured to optically couple to a photodetector via a fiber bundle, at least one photonic integrated circuit (PIC) disposed directly atop a substrate, wherein the at least one photonic integrated circuit comprises at least one first grating coupler aligned with the optical input port, at least two second grating couplers aligned with the optical output port, at least one waveguide between the first grating coupler and the second grating couplers, and at least one detection element disposed within the at least one waveguide.

A biowearable sensor device is disclosed with improved features in the microneedle array and the electronics unit which, without limitation, reduce damage to the microneedles from excessive force which can occurring during placement, and verify proper placement of the microneedle tips in a biofluid in the skin layers of the wearer, both during placement and the entire life of the device.

We provide a necklace-type terminal equipped with an environmental sensor device and a biosensor device. [Solution] The necklace-type terminal is worn by a mobile organism to collect data in an area where plants are grown. The necklace-type terminal includes a biosensor device, an environmental sensor device, an acoustic collector that detects acoustic vibrations including sound waves from outside the necklace-type terminal and sound waves emitted by the organism, a data collection unit that collects data signals from the biosensor device, the environmental sensor device, and the acoustic collector and generates output data, a first communication unit configured to receive output data from the data collection unit and capable of communicating with a data processing device located outside the necklace-type terminal, and an electroacoustic converter that converts electrical signals from the first communication unit into acoustic vibrations. The environmental sensor device includes an optical sensor device that detects light at the location of the necklace-type terminal.

The present invention discloses a highly reliable implantable device of an implantable biological sensor. Before use, the fixed seat cannot move relative to the slidable seat, achieving reliable transportation. In use, the lower end face of the slidable seat is pressed against the skin; the lower end face of the first snap-fit protrusion squeezes the upper end face of the vertical snap-fit plate; the first snap-fit protrusion is gradually away from the support of the vertical snap-fit plate, whereby the inside vertical face of the vertical snap-fit plate pushes the first snap-fit protrusion inward, and the fixed seat moves downward relative to the slidable seat, achieving good controllability.

The invention discloses a CMOS compatible biosensor based on a two-dimensional semiconductor and a preparation method and application of the CMOS compatible biosensor, specifically, an aluminum nitride layer compatible with a CMOS process is deposited on a silicon substrate, a two-dimensional semiconductor layer is formed on the surface of the aluminum nitride layer to serve as a sensing layer, and meanwhile a biological recognition element is fixed. The two-dimensional semiconductor layer is used for being combined with target biomolecules to generate a reaction product with electron donating and receiving capability, so that the reaction product is subjected to efficient charge transfer on the two-dimensional semiconductor layer, and the conductive detection layer can output sensitive and controllable signal change; the band gap characteristic and the high surface area of the two-dimensional semiconductor are utilized, the aluminum nitride and the silicon substrate are combined for use to achieve CMOS compatibility of the biosensing device, and due to the fact that the two-dimensional semiconductor has the excellent optical absorption and emission characteristics, the biosensing device can also be expanded to optical biosensing, optical biosensing and the like. Coupling detection of photoelectric signals and chemical or biological events is achieved, and the application range and multifunctionality are further expanded.