The invention provides a selenium-rich rice wine production process. The production process comprises the following steps: firstly, pouring coarse glutinous rice into a sodium selenite aqueous solution, and inducing germination to obtain germ glutinous rice; then grinding the germ glutinous rice into rice flour, spreading the rice flour to be thin, uniformly spraying a sodium selenite aqueous solution on the surface of the rice flour, steaming for the first time, transferring into a square mold, pressing, demolding, and steaming for the second time to obtain a substrate; then, inoculating morchella strains into the substrate, carrying out spawn running, and obtaining glutinous rice blocks with morchella hyphae; crushing the glutinous rice blocks into glutinous rice flour, washing with water, degreasing, steaming, spreading for cooling, mixing with rhizopus koji, fermenting, and filtering to obtain filtrate; and finally, adding Nanguo pear juice into the filtrate, carrying out microwave treatment, naturally cooling, ageing, filtering and sterilizing to obtain the rice wine. According to the present invention, the obtained rice wine is high in selenium and gamma-aminobutyric acid content, and high in nutritive value; and common glutinous rice is used as a raw material, selenium-rich rice does not need to be specially used, and better production flexibility is achieved.