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11 results about "Select agent" patented technology

Under United States law, "biological select agents or toxins" (BSATs) — or simply select agents for short — are bio-agents which (since 1997) have been declared by the U.S. Department of Health and Human Services (HHS) or by the U.S. Department of Agriculture (USDA) to have the "potential to pose a severe threat to public health and safety". The agents are divided into (1) HHS select agents and toxins affecting humans; (2) USDA select agents and toxins affecting agriculture; and (3) overlap select agents and toxins affecting both.

Methods of producing modified rubus

PCT designated stageWO2025264522A1Plant tissue cultureHorticulture methodsBiotechnologyRubus vestitus
Described herein are methods for producing a modified Rubus species plant or plant part. The method can include introducing a polynucleotide of interest (e.g., a portion of an editing system) and a gene that confers resistance to a selection agent into one or more meristem cells of a wounded tissue including meristem cells to provide a transformed tissue, culturing the transformed plant tissue in the presence of the selection agent in an amount at least 1.5 times that needed to kill 90% of Rubus spp. cells to provide a cultured transformed tissue, and regenerating a Rubus spp. plant or plant part from the cultured transformed tissue.
Owner:PAIRWISE PLANTS SERVICES INC

Molecular recogntion assays of critical structure attributes in proteoforms

PendingUS20260126451A1Component separationBiological testingSelect agentAssay
A method is provided to simultaneously identify and quantify critical structure attributes (CSAs) in proteoforms or proteoform families that includes the steps of:1. injecting a sample into a reagent stream of one or more detection enhanced molecular recognition reagents;2. incubating the combined sample:reagent(s) during migration through an analytical platform the causes molecular recognition reagent(s) to be sequestered by a specific critical structure attribute (CSA) in the analyte to form a luminon (An:*Sas) complex;3. using a sequestron selector in the reagent stream to overtake the luminon complex in a down-stream size exclusion chromatography (SEC) column to achieve mixing and formation of an Nc˜Pas:An:*Sas, Pas:An:*Sas, or *Pas:An:*Sas sequestome complex;4. resolving this sequestome complex from any unbound affinity selector(s) such as *Sas or *Pas, and non-analytes in the SEC column;5. transporting the resolved sequestome complex into a flow-through detection means that detects and quantifies CSAs in fluorescent labeled *Sas or *Pas bearing luminon or sequestome complex to generate data for the construction of critical structure attribute ratio plots as a function of elapsed fermentation time.
Owner:NOVILYTIC LLC

Operation and maintenance task processing method and device, equipment, readable storage medium and product

ActiveCN121745922AInstrumentsSelect agentOperating system
The invention relates to an operation and maintenance task processing method and device, equipment, a readable storage medium and a product. The method comprises the steps that for each operation and maintenance task in a current scheduling period, the tension value of the operation and maintenance task is evaluated based on a task tuple of the operation and maintenance task, and the task tuple at least comprises the task type, the expected task time period, the capability demand vector and the task position of the operation and maintenance task; based on the tension value of each operation and maintenance task, a target capability template of each agent in the current scheduling period is determined, and the target capability template is used for indicating the operation and maintenance capability configured by the corresponding agent; and for each operation and maintenance task, based on the task tuple of the operation and maintenance task and the target capability template of each agent, determining the cost score of each agent for executing the operation and maintenance task, based on the cost score of each agent, selecting the agent for executing the operation and maintenance task from the plurality of agents, and executing the operation and maintenance task according to the selected agent. And the operation and maintenance task processing efficiency is improved.
Owner:SHENZHEN POWER SUPPLY BUREAU

Picking robot arm control method based on density clustering and agent integration

ActiveCN119458329BSelect agentRobotic arm
This invention belongs to the field of robotic arm motion planning and control technology, and discloses a control method for a harvesting robotic arm based on density clustering and agent integration. First, the DBSCAN algorithm is used to simplify the harvesting scenario, determining the objective function, constraints, input state space, action space, reward function, and termination condition of the agent in the harvesting scenario model. Based on the clustering results of the DBSCAN algorithm, the agent is prepared for training. Then, the selected agent algorithm is trained. Finally, an error reciprocal weighted combination method based on agent reward is used to integrate the motion control decisions of each trained agent algorithm for the same robotic arm and accumulate the total reward value after integration processing. This invention is applicable to the control of harvesting robotic arms, realizes multi-angle decision-making, effectively compensates for the shortcomings of single algorithms, improves the accuracy of robotic arm motion, and thus provides reliable support for modern agricultural automation technology.
Owner:HEBEI ELECTROMECHANICAL INTEGRATION PILOT BASE CO LTD

Compositions, methods and systems for detecting methicillin-resistant staphylococcus aureus

Disclosed are compositions, methods, and systems for detecting MRSA, such as nasal colonization of MRSA. In certain embodiments, the methods use phage-based signal amplification in the detection of bacteria and other microorganisms to detect MRSA. The method for detecting MRSA may comprise: preparing an assay comprising a selection agent and a mixture comprising at least two different types of recombinant bacteriophages; incubating a sample in the assay; capturing an indicator protein product; and detecting an indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates the presence of MRSA in the sample.
Owner:LABORATORY CORPORATION OF AMERICA HOLDINGS INC

Operation and maintenance task processing method and device, equipment, readable storage medium and product

ActiveCN121745922BInstrumentsSelect agentOperating system
The application relates to an operation and maintenance task processing method and device, equipment, a readable storage medium and a product. The method comprises the following steps: for each operation and maintenance task in a current scheduling period, evaluating a tension value of the operation and maintenance task based on a task tuple of the operation and maintenance task, the task tuple at least comprising a task type, an expected task period, a capability demand vector and a task position of the operation and maintenance task; determining a target capability template of each agent in the current scheduling period based on the tension values of the operation and maintenance tasks, the target capability template being used for indicating an operation and maintenance capability configured for the corresponding agent; for each operation and maintenance task, determining a cost score of each agent for executing the operation and maintenance task based on the task tuple of the operation and maintenance task and the target capability templates of the agents; and selecting an agent for executing the operation and maintenance task from the multiple agents based on the cost scores of the agents, and executing the operation and maintenance task according to the selected agent, thereby improving the operation and maintenance task processing efficiency.
Owner:SHENZHEN POWER SUPPLY BUREAU

Molecular recogntion assays of critical structure attributes in proteoforms

ActiveUS12510546B2Component separationBiological testingSelect agentAssay
A method is provided to simultaneously identify and quantify critical structure attributes (CSAs) in proteoforms or proteoform families that includes the steps of:1. injecting a sample into a reagent stream of one or more detection enhanced molecular recognition reagents;2. incubating the combined sample:reagent(s) during migration through an analytical platform the causes molecular recognition reagent(s) to be sequestered by a specific critical structure attribute (CSA) in the analyte to form a luminon (An:*Sas) complex;3. using a sequestron selector in the reagent stream to overtake the luminon complex in a down-stream size exclusion chromatography (SEC) column to achieve mixing and formation of an Nc˜Pas:An:*Sas, Pas:An:*Sas, or *Pas:An:*Sas sequestome complex;4. resolving this sequestome complex from any unbound affinity selector(s) such as *Sas or *Pas, and non-analytes in the SEC column;5. transporting the resolved sequestome complex into a flow-through detection means that detects and quantifies CSAs in fluorescent labeled *Sas or *Pas bearing luminon or sequestome complex to generate data for the construction of critical structure attribute ratio plots as a function of elapsed fermentation time.
Owner:NOVILYTIC LLC

Compositions, methods, and systems for detecting methicillin-resistant Staphylococcus aureus

This invention provides compositions, methods, apparatus, systems, and kits for detecting nasal cavity colonization of MRSA. [Solution] In a particular embodiment, the method uses bacteriophage-based amplification of signals in the detection of bacteria and other microorganisms to detect MRSA. The method for detecting MRSA may include preparing an assay comprising a selectant and a cocktail comprising at least two different types of recombinant bacteriophages, incubating a sample in the assay, capturing an indicator protein product, and detecting the indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates the presence of MRSA in the sample.
Owner:LABORATORY CORPORATION OF AMERICA HOLDINGS INC

Compositions, methods, and systems for detecting methicillin-resistant staphylococcus aureus

Compositions, methods, and systems for detecting MRSA, such as MRSA nasal colonization, are disclosed. In certain embodiments, the methods use phage-based signal amplification in the detection of bacteria and other microorganisms to detect MRSA. The methods for detecting MRSA can include preparing an assay comprising a selection agent and a mixture comprising at least two different types of recombinant bacteriophage; incubating a sample in the assay; capturing an indicator protein product; and detecting the indicator protein product produced by the recombinant bacteriophage, wherein a positive detection of the indicator protein product indicates that MRSA is present in the sample.
Owner:LABORATORY CORPORATION OF AMERICA HOLDINGS INC

Systems and methods for relative gain in predictive routing

According to one embodiment, a method for routing interactions to contact center agents includes identifying interactions to be routed to contact center agents; determining a predictive routing score for each predicted contact center agent to which the interaction may be routed based on each predicted agent's past performance; determining a relative gain for each predicted agent based on the interaction class of the interaction, the predicted agent's agent class performance, and the predicted agent's agent value, where the relative gain for each agent indicates a relative optimization improvement in routing of the interaction to the respective agent compared to another predicted agent; ranking the predicted agents based on the predictive routing score and associated relative gain associated with each predicted agent; and routing the interaction to a selected agent based on the ranking of the predicted agent.
Owner:GENESIS CLOUD SERVICES CO LTD