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68 results about "Polygonatum sibiricum" patented technology

Polygonatum sibiricum is a PERENNIAL growing to 1 m (3ft 3in). It is hardy to zone (UK) 3. It is in flower from May to June, and the seeds ripen from Aug to September. The species is hermaphrodite (has both male and female organs) and are pollinated by Bees, self.The plant is self-fertile.

A method for extracting soluble dietary fiber from polygonatum residue

PendingCN122271561ABiotechnologyMicrobiology
This invention discloses a method for extracting soluble dietary fiber from Polygonatum sibiricum residue, belonging to the field of traditional Chinese medicine extraction technology. This invention provides a method for extracting soluble dietary fiber from Polygonatum sibiricum residue with high yield, and discovers that this soluble dietary fiber can effectively resist oxidation, significantly improve the richness and uniformity of gut microbiota, improve gut microbiota composition imbalance, promote the proliferation of beneficial bacteria, inhibit the excessive growth of harmful bacteria, and play a protective role against intestinal damage by regulating the structure of intestinal microbiota and maintaining microecological stability, showing broad application prospects.
Owner:CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and preparation method of traditional Chinese medicine tea drink

PendingCN122075630AImprove microcirculationlow recurrence ratePowder deliveryDigestive systemMedicinal herbsDisease
The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.
Owner:WEST CHINA STOMATOLOGICAL HOSPITAL OF SICHUAN UNIV

Tray for yellow finish machining

ActiveCN224268259UAvoid the problem of accumulation covering the liquid outlet holeeasy dischargePharmaceutical product form changeFood shapingMechanical engineeringPolygonatum sibiricum
A tray for yellow finish machining relates to the technical field of yellow finish machining and comprises a tray bottom (1) and a tray edge (2) extending outwards along the edge of the tray bottom (1), the section of the tray bottom (1) is in a continuous wave shape, wave crest portions and wave trough portions which are distributed alternately are formed, a plurality of liquid outlet holes (11) are vertically formed in the wave trough portions, a liquid collecting groove (12) is further formed in the lower side of the tray bottom (1), and a liquid outlet (121) is formed in one side of the liquid collecting groove (12). An adjusting assembly (3) is arranged on the side, opposite to the liquid outlet (121), of the plate edge (2), and the adjusting assembly (3) is arranged to be capable of adjusting the inclination angle of the plate bottom (1). Polygonatum sibiricum materials are supported through the wave crest parts of the plate bottom, the situation that liquid outlet holes are blocked due to material covering of a traditional plane plate bottom is avoided, and juice and water vapor generated in the steaming process can be rapidly discharged through the liquid outlet holes of the wave trough parts; the adjusting assembly can dynamically adjust the inclination angle of the tray bottom, so that liquid flows to the liquid outlet along the liquid collecting tank and flows out, the liquid discharging efficiency is remarkably improved, and the follow-up sun-curing quality of rhizoma polygonati is improved.
Owner:SHANDONG TAISHANG HUANGJING BIOTECHNOLOGY CO LTD

A kind of water culture device for breeding of polygonatum sibiricum

ActiveCN224402484UMeet individual needsless consumablesWater storageFishery
The utility model discloses a kind of water culture devices for yunnan rhizoma polygonati breeding, it is related to yunnan rhizoma polygonati cultivation technical field, including culture rack, the culture rack is slidably connected with multiple water storage channels, and the water storage channel upper end is provided with culture plate;Multiple planting holes are evenly provided in the culture plate, and the culture plate upper end is connected with multiple fixed components, and fixed component is located planting hole outer end.The utility model design structure is reasonable, it can simultaneously carry different batches, different genotypes yunnan rhizoma polygonati breeding material, while independent water supply head, gate plate can individually adjust the water supply of each water storage channel, water supply frequency, realize the accurate management of "one tank one strategy", satisfy the individualized demand of different breeding material, to improve the success rate of breeding, can avoid the problem of "excessive supply" or "insufficient supply" caused by unified water supply, accurately match the demand of each growth stage of yunnan rhizoma polygonati, save water resource, nutrient solution and other consumables, reduce breeding cost.
Owner:YUNNAN MINDING AGRICULTURAL DEVELOPMENT CO LTD

A method for extracting acrylamide in rhizoma polygonati and its application in liquid chromatography detection

This invention belongs to the field of traditional Chinese medicine processing and testing technology, and relates to an ultrasonic-assisted extraction method and content determination method for acrylamide in processed Polygonatum sibiricum. The optimal extraction process for acrylamide from processed Polygonatum sibiricum is as follows: 1.0 g of Polygonatum sibiricum, 6 mL of a mixed solution of ethyl acetate and methanol as the extractant (volume ratio 6:4), ultrasonic time of 15 min, and ultrasonic power of 180 W. After purification using a C18 solid-phase extraction column, the acrylamide content was found to be 0.498 ± 0.0015 μg / g. This method is stable and reliable. Compared with a single water extractant, using a mixed solution of ethyl acetate and methanol as the extractant significantly improves the extraction efficiency, and the operation is simple, showing good market application prospects and industrial applicability.
Owner:JILIN INST OF CHEM TECH

A method for reducing chemical sensing substances and increasing polysaccharide content in polygonatum sibiricum planting

The present application provides a kind of planting method of reducing allelochemicals and improving polysaccharide content of Rhizoma Polygonati, belongs to plant cultivation technical field.The planting method is planted in acidic sandy loam soil, and "biochar C" is applied to the soil 1-2 times in September-October of the second and third years, and the fruits mature, the stems are laid down after the third year, and then it can be harvested."Biochar C" is a modified, loaded with salicylic acid and UDP-D-galactose biochar.The present application not only helps to improve the physicochemical properties and bacterial community diversity of Rhizoma Polygonati planting soil, thereby reducing the allelochemicals content of Rhizoma Polygonati rhizome, but also can improve the polysaccharide content of rhizome, which helps to improve the quality of Rhizoma Polygonati and enhance its efficacy.
Owner:CROP RES INST OF FUJIAN ACAD OF AGRI SCI

A medicinal and edible composition capable of reducing the glycemic effect of carbohydrates

ActiveCN118634296BAdjustable for Qi and Yin deficiencyReduce glycemic effectMetabolism disorderConfectioneryBiotechnologyDiabetes mellitus
The application discloses a kind of medicine-food homologous compositions that can reduce the glycemic effect of carbohydrates.The composition includes the following components: polygonatum sibiricum, pueraria, polygonatum, mulberry leaf, raspberry, yizhi ren, peach kernel, orange peel, fried wheat, sea buckthorn.The whole party can adjust the deficiency of both qi and yin of organism, and can also reduce the glycemic effect caused by carbohydrates, and has the advantages of treating the root and branch of diabetes and overall regulation.Raspberry, orange peel, fried wheat, sea buckthorn components can synergistically enhance efficacy, further enhance efficacy.
Owner:BEIJING SCI & TECH PATENT OFFICE

A sieving and residue removal device for Polygonatum tea

This utility model relates to the field of screening and slag removal technology, and proposes a screening and slag removal device for Polygonatum sibiricum tea. It includes a processing box and an arc-shaped screen located inside the processing box. Two fixed plates are connected to the inner wall of the processing box, and two support plates are connected to the outer wall of the arc-shaped screen near the top. An arc-shaped through groove and a semi-circular through groove are respectively opened at both ends of the processing box. A first arc-shaped extension and a second arc-shaped extension are respectively connected to both ends of the arc-shaped screen, penetrating the arc-shaped through groove and the semi-circular through groove. A first motor is installed on the outer wall of the processing box, and a rotating disk is connected to the output end of the first motor. A control block is connected to the top of the rotating disk near the edge, and a control groove is slidably connected to the control block. An arc-shaped connector is connected to the control groove, thereby facilitating the replacement of the screen, achieving the purpose of easy cleaning and improving work efficiency.
Owner:HUBEI MINGSEN ECOLOGICAL AGRICULTURE CO LTD

A type of Solomon's Seal planting rack

This utility model relates to the technical field of Polygonatum sibiricum, and in particular to a Polygonatum sibiricum planting rack. Through the cooperation of a planting adjustment mechanism and multiple anti-lodging mechanisms, it facilitates the adjustment of Polygonatum sibiricum during its growth process. A protective mechanism shields the planting rack to prevent external impurities or insects from affecting the cultivation and production of Polygonatum sibiricum, thus improving the cultivation effect. The planting rack is fixedly installed on the base plate, and two fixed plates are symmetrically fixedly installed on the planting rack. A planting adjustment mechanism is provided on the planting rack, comprising multiple planting trays and two first screws. Each planting tray is slidably connected to the planting rack, and two adjustment plates are symmetrically fixedly installed on each planting tray. A motor is fixedly installed on one of the fixed plates. Both first screws are rotatably connected to the base plate, and one end of one first screw is fixedly connected to the output end of the motor. Each adjustment plate is screwed onto its corresponding first screw.
Owner:HUBEI CHONGZHEN AGRICULTURAL TECHNOLOGY CO LTD

Five treasures pill prepared from five Chinese medicinal ingredients of astragalus root, rhizoma polygonati, prepared rehmannia root, poria and dried tangerine or orange peel and its preparation method

PendingCN122351381AFormularyDisease
This invention relates to a Five Elements Pill composed of five traditional Chinese medicines: Astragalus membranaceus, Polygonatum sibiricum, Rehmannia glutinosa, Poria cocos, and Citrus reticulata peel, and its preparation method. In this Five Elements Pill, Astragalus membranaceus is the principal ingredient, Polygonatum sibiricum and Rehmannia glutinosa are the assistant ingredients, Poria cocos is the adjuvant ingredient, and Citrus reticulata peel is the guiding ingredient. This invention, based on the principles of the Five Elements theory and the philosophy of syndrome differentiation and treatment, carefully selects and combines these five traditional Chinese medicines. The formula is precise and rational, with significant therapeutic effects, suitable for medicinal and health maintenance use by middle-aged and elderly people, and can meet their needs for disease prevention, chronic diseases, and geriatric diseases. This invention combines modern and traditional methods, making it practically applicable and producing high-quality, qualified products that meet social needs.
Owner:郜海晶

Huangqin processing, screening and impurity removing device

ActiveCN224272099UImprove the efficiency of impurity removalclean up thoroughlySievingScreeningElectric machineryStructural engineering
This utility model relates to the technical field of impurity removal equipment for processing Polygonatum sibiricum, and in particular to a screening and impurity removal device for processing Polygonatum sibiricum. It can effectively reduce the labor intensity of workers, improve screening and impurity removal efficiency, make the screening and impurity removal of Polygonatum sibiricum rhizomes more thorough, and improve practicality. It includes a base, a shaking screen mechanism, and a filling assembly. The shaking screen mechanism includes a motor and a shaking screen frame. Two sets of upright plates are symmetrically fixedly connected to the top of the base. The front end of one set of upright plates is fixedly installed below the motor. A transmission crankshaft is fixedly connected to the output end of the motor. The transmission crankshaft is rotatably mounted on the two sets of upright plates. The shaking screen frame is rotatably mounted on the two sets of upright plates via a rotating shaft. Support plates are fixedly connected to the inner walls on both sides of the shaking screen frame. A connecting rod is fixedly connected to the center of the bottom end of the shaking screen frame. The connecting rod has a guide groove, and the connecting rod is slidably fitted onto the transmission crankshaft through the cooperation of the guide groove. The filling assembly includes a screen cylinder for filling Polygonatum sibiricum rhizomes.
Owner:HUBEI MINGSEN ECOLOGICAL AGRICULTURE CO LTD

A preparation of Polygonatum sibiricum vesicles for treating premature ovarian failure, its preparation method and application

PendingCN122303128APremature agingGranular leucocyte
This invention discloses a Polygonatum sibiricum vesicle preparation for treating premature ovarian failure, its preparation method, and its application. The preparation method includes: cleaning Polygonatum sibiricum, juicing, filtering to remove residue, and collecting the juice; subjecting the juice to gradient centrifugation to remove residual plant tissue, plant cells, and plant cell debris; then using an extraction reagent for stepwise precipitation, collecting the precipitate, and resuspending it to obtain the final product. The Polygonatum sibiricum vesicle preparation prepared by this invention can be efficiently taken up by ovarian granulosa cells. It effectively treats premature ovarian failure by activating the Nrf2 signaling pathway, upregulating antioxidant enzyme expression, scavenging reactive oxygen species, restoring mitochondrial membrane potential, inhibiting apoptosis, and restoring the expression levels of estrogen, follicle-stimulating hormone, and anti-Müllerian hormone. The preparation method of this invention is standardized, biocompatible, and safe, and has broad clinical application prospects.
Owner:SOUTHEAST UNIV

A composition for protecting cochlear ganglion neurons and use thereof

PendingCN122251463Aimprove survival ratePromote neurite growthOrganic active ingredientsSenses disorderHL - Hearing lossSensorineural hearing loss
The present application relates to the technical field of biological medicine, and particularly relates to a composition for protecting cochlear spiral ganglion neurons and application thereof. The composition comprises Panax notoginseng saponins (PNS) and Polygonatum sibiricum polysaccharide (PSP). Research shows that the composition can significantly improve the survival rate of neurons, promote neurite growth, reduce the level of reactive oxygen species, inhibit cell apoptosis, and promote autophagy by regulating the PI3K / AKT signaling pathway, thereby effectively resisting ototoxicity damage induced by aminoglycoside antibiotics. The present application further provides the use of the composition in the preparation of a drug for preventing or treating sensorineural hearing loss.
Owner:潘意寅

A device for cultivating and domesticating polygonatum sibiricum

ActiveCN224402375UGood resistance to lodging and domesticationImprove domestication effectPolygonatum sibiricumSeedling
The utility model is suitable for the field of huangjinyen domestication technology, provide a kind of huangjinyen domestication device, including: for the domestication of huangjinyen seedling and domestication is cultivated domestication box;It is cultivated for the domestication of huangjinyen seedling and is cultivated in the domestication box, domestication frame;Two vertical pipes of symmetry rotation installation on the domestication box, multiple horizontal pipes are all provided on two the vertical pipe, the air outlet is all set up on the vertical pipe and the horizontal pipe;Fan is fixedly installed on the domestication box, the air outlet end of the fan is connected with two hoses, two the hose is linked with two the vertical pipe respectively.The huangjinyen domestication device provided by the utility model can cultivate and domesticate huangjinyen seedlings, and can simulate uncertain wind direction in nature, so that the huangjinyen seedlings can be better domesticated against lodging, and the domestication effect of huangjinyen seedlings is effectively improved.
Owner:FENGQING HENGRUN AGRI DEV CO LTD

Preparation method of a rhizoma polygonati enzyme liquid

PendingCN122074642AImprove creativityretain activityFungiBacteriaBiotechnologyEnzymatic hydrolysis
This invention discloses a method for preparing Polygonatum sibiricum enzyme liquid, belonging to the field of bio-fermentation technology. The method includes: gradient permeation activation treatment of Polygonatum sibiricum, including negative pressure pulsating permeation and reduced pressure concentration under inert gas protection; preparation and co-inoculation of a composite strain of Lactobacillus plantarum and Saccharomyces cerevisiae propagated in a stepwise sequential manner; multi-stage temperature and pressure-coupled fermentation, including pressurized microaerobic primary fermentation and high-temperature static incubation for enhanced conversion; targeted induction of enzymatic hydrolysis and low-temperature maturation; and in-situ aseptic filling. This invention does not add any other ingredients throughout the entire process. Through a series of original, interrelated process steps and precise parameter control, it solves the technical problem of efficiently converting a single Polygonatum sibiricum raw material into a high-quality enzyme liquid, ultimately producing a pure Polygonatum sibiricum enzyme liquid with high active substance content, mellow taste, and excellent stability.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

A wild-simulated planting method of polygonatum sibiricum in forest

This invention belongs to the field of plant cultivation technology, specifically a method for simulating wild cultivation of Polygonatum sibiricum under forest cover. The method includes the following steps: S1, cultivating edible fungi under the forest canopy. After harvesting the fungi, the remaining mycelial network and organic matter are used to form a fungal residue layer, naturally improving the forest soil. The forest soil is then divided into multiple equidistantly distributed semi-buried modular simulated wild cultivation troughs. This method for simulating wild cultivation of Polygonatum sibiricum under forest cover, by setting up semi-buried modular simulated wild cultivation troughs and employing a multi-layered soil structure consisting of a biomimetic surface cover layer, a planting substrate layer, a moisture-retaining buffer layer, a drainage layer, and an isolation layer, constructs a highly simulated forest micro-ecological environment, achieving natural soil improvement and sustainable utilization, and effectively enhancing the quality and medicinal components of Polygonatum sibiricum.
Owner:CHONGQING JIUHUAFU AGRICULTURE CO LTD

A pretreatment and modification method for dietary fiber in ready-to-eat Polygonatum sibiricum

This invention discloses a pretreatment modification method for dietary fiber in ready-to-eat Polygonatum sibiricum, belonging to the field of food engineering technology. S1: Place the Polygonatum sibiricum raw material in a steam flash explosion device, introduce saturated steam at a pressure of 1.2-1.6 MPa and a temperature of 180-200℃, maintain pressure for 90-150 seconds, then release pressure to atmospheric pressure to obtain flash-exploded Polygonatum sibiricum material; S2: Mix the flash-exploded Polygonatum sibiricum material with water to form a slurry, and sequentially perform enzymatic hydrolysis of endo-cellulosic composite cellulose, hemicellulose, and debranched cellulose, with enzyme inactivation treatment after each hydrolysis step to obtain enzymatically hydrolyzed Polygonatum slurry. This invention shortens the traditional 15-day production cycle to less than 24 hours, realizing a shift from natural experience to digital intelligent manufacturing. The batch-to-batch stability of key indicators is far superior to that of traditional processes, laying a technical foundation for industrialized and standardized production.
Owner:TIBET MILIN TIBETAN MEDICINE VALLEY PHARMACEUTICAL CO LTD +2

A pH adjustment device for gold refining waste liquid

This application provides a pH adjustment device for gold refining waste liquid, including a reaction chamber internally containing the waste liquid and a reaction body with a first discharge port and a second discharge port communicating with the reaction chamber. It also includes two feeding hoppers connected to the first and second discharge ports. The first discharge port is used to add solid NaOH to adjust the pH of the waste liquid, and the second discharge port is used to add Polygonatum sibiricum waste liquid into the reaction chamber. It further includes a stirring mechanism, with a first stirring assembly and a second stirring assembly extending into the reaction chamber. The first and second stirring assemblies are symmetrically arranged along the width of the reaction chamber and staggered along the height of the reaction chamber. The first stirring assembly is located near the bottom of the reaction chamber and adheres to the inner wall of the reaction body, while the second stirring assembly is located near the top of the reaction chamber. This structure improves the mixing efficiency between the upper and lower layers.
Owner:SHENZHEN JINZHENGLONG TECH CO LTD

A traditional Chinese medicine compound preparation and its application in the preparation of drugs for treating cardiovascular and cerebrovascular diseases

PendingCN122297609APlatelet aggregation ratioAntithrombotic
This invention provides a traditional Chinese medicine compound preparation and its application in the preparation of drugs for treating cardiovascular and cerebrovascular diseases, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine compound preparation comprises the following raw materials in parts by weight: 10-20 parts bee pollen, 8-15 parts curcumin, 5-10 parts γ-aminobutyric acid, 5-12 parts Litsea cubeba leaf, 10-20 parts hawthorn, 5-10 parts Lindera strychnifolia leaf, 10-20 parts kudzu root, 5-12 parts ginseng, 8-15 parts Polygonatum sibiricum, 6-12 parts Sophora japonica flower bud, 3-8 parts tangerine peel, and 1-5 parts L-cysteine. This invention significantly improves the water solubility, stability, and bioavailability of curcumin by constructing a chlorophyll zinc / LDH nanosheet composite carrier to load curcumin. A compound preparation of traditional Chinese medicine was prepared by combining a complex loaded with curcumin with various food and medicine homologous ingredients. This traditional Chinese medicine compound preparation can significantly reduce whole blood viscosity, plasma viscosity and platelet aggregation rate in rats with acute blood stasis model, has anti-thrombotic effect, and significantly promotes the recovery of neurological function in rats with focal cerebral ischemia and reduces the volume of cerebral infarction.
Owner:SHANGHAI DUNPANG IND DEVELOPMENT CO LTD +1

A herbal rice wine for lowering blood lipids and its preparation method

PendingCN122081022Ahigh in flavonoidsDefinitely lower blood lipidsMetabolism disorderAlcoholic beverage preparationBiotechnologyFermentation
This invention relates to the field of rice wine brewing technology, specifically disclosing a herbal rice wine for lowering blood lipids and its production method. The rice wine uses Yangxian glutinous rice and Yangxian black rice as main raw materials, combined with ten medicinal and edible herbal ingredients: Polygonatum sibiricum, wolfberry, gardenia, chrysanthemum, hawthorn, lotus leaf, licorice, peach kernel, kudzu root, and cassia seed. It is produced through processes including crushing, koji making, fermentation, pressing, decoction, aging, blending, and sterilization. The beneficial effects are: through scientific formulation, this invention enables the synergistic effect of various herbal components, significantly increasing the content of flavonoids in the rice wine, resulting in good blood lipid-lowering and cardiovascular protection effects; using medicinal and edible ingredients, it is safe and has no side effects, suitable for long-term consumption; the process is mature, easy for industrial production, and the product quality is stable; experimental verification shows that its blood lipid-lowering effect is superior to ordinary rice wine and similar products on the market.
Owner:SHAANXI QINYANG CHANGSHENG WINERY

Three-element hormone complex solution and germination method for promoting seed germination of tetraploid polygonatum

PendingCN122350109AStratification (seeds)Salicylic acid
This invention relates to the field of agricultural biotechnology and discloses a ternary hormone complex solution for promoting the germination of tetraploid Polygonatum sibiricum seeds. By mass percentage, it consists of the following raw materials: gibberellin 0.005%–0.02%, 6-benzyladenine 0.0005%–0.002%, salicylic acid 0.0005%–0.002%, with the balance being water. The germination method includes the following steps: S1: seed pretreatment; S2: hormone soaking; S3: substrate sterilization; S4: sand stratification for germination. This ternary hormone complex solution and germination method can significantly improve the germination rate of tetraploid Polygonatum sibiricum seeds and effectively reduce the mold rate during the seed germination period.
Owner:CHONGQING ENERGY COLLEGE

Sulfated polygonatum sibiricum polysaccharide, a preparation method thereof and application thereof in preparation of a medicine for treating liver cancer

This invention belongs to the field of antitumor drugs, disclosing a sulfated Polygonatum sibiricum polysaccharide, its preparation method, and its application in the preparation of drugs for treating liver cancer. The invention uses dried Polygonatum sibiricum rhizome as raw material, purifies it to obtain Polygonatum sibiricum polysaccharide, and then uses a sulfur trioxide-pyridine complex as a sulfation reagent to perform sulfation modification, thus preparing sulfated Polygonatum sibiricum polysaccharide. Sulfated Polygonatum sibiricum polysaccharide significantly improves water solubility, optimizes molecular spatial conformation and charge distribution, and induces cancer cell apoptosis by damaging mitochondrial membrane potential, increasing intracellular ROS levels, and downregulating the expression of key phosphorylated proteins in the PI3K / Akt / mTOR signaling pathway. In animal experiments, it effectively inhibited tumor growth without causing significant systemic toxicity in mice, demonstrating good in vivo biocompatibility. Therefore, it has important application value.
Owner:WANNAN MEDICAL COLLEGE

Selenium-rich medicinal and edible compound preparation for improving diabetic encephalopathy and preparation and application thereof

This invention relates to the field of traditional Chinese medicine and health food preparation technology, and discloses a selenium-enriched medicinal and edible compound preparation for improving diabetic encephalopathy, as well as its preparation and application. The preparation is made from a specific weight ratio of Codonopsis pilosula, Astragalus membranaceus, Polygonatum sibiricum, selenium-enriched Corydalis yanhusuo, and Morus alba leaves. The preparation method includes raw material pulverization, constant-temperature reflux extraction with water, filtration and purification using a 0.22μm microporous membrane, vacuum low-temperature concentration to extract, and addition of excipients to form granules, capsules, or tablets. This invention constructs a multi-target synergistic network integrating qi replenishment, blood sugar control, and nerve protection through scientific formulation. It utilizes the strong antioxidant properties of organic selenium to efficiently scavenge free radicals in the brain, improving cognitive impairment caused by diabetic encephalopathy and lowering blood sugar. Combined with a mild closed-loop process and microfiltration technology, it ensures the stability and dissolution rate of heat-sensitive active ingredients, improving the purity, safety, and batch-to-batch consistency of the preparation.
Owner:HUBEI UNIV FOR NATITIES +1

Veterinary immunity-enhancing antiviral powder and preparation method thereof

ActiveCN117461761BAntipyreticAnalgesicsPorcine serumCrataegus pinnatifida
The present application relates to a kind of veterinary immunity-enhancing antiviral powder and its preparation method, the veterinary immunity-enhancing antiviral powder includes traditional Chinese medicine fermentation powder 60-70%, phoenix tree seed oil 20-30% and dioscorea opuloides mucopolysaccharide 10-20% according to mass percentage;The traditional Chinese medicine fermentation powder is first obtained fermentation product using bacillus velezensis, Candida utilis fermentation scutellaria baicalensis, astragalus, pomegranate peel, hawthorn and polygonatum sibiricum, then is formed by drying, ultrafine grinding to fermentation product.This application can improve the quality concentration of piglet serum immunoglobulin, so that piglet immunity, antiviral capacity is improved, in addition, it has good therapeutic effect on piglet viral gastroenteritis.
Owner:ANHUI ZHONGLONG GUOCHUANG BIOTECHNOLOGY CO LTD

A device for soaking and washing the Chinese herb Polygonatum sibiricum

ActiveCN224423675UProcess engineeringPlant Tubers
This utility model discloses a soaking and washing device for the traditional Chinese medicine Polygonatum sibiricum, characterized by comprising a soaking cylinder, within which a soaking chamber structure is provided; the soaking chamber structure includes a chamber cylinder with several soaking holes; a detachable cover is installed on the top of the chamber cylinder; a bottom turntable is rotatably connected to the bottom of the soaking cylinder to drive the chamber cylinder to rotate; the soaking chamber is limited on the bottom turntable by a guide wheel structure, the guide wheel structure including several wheel brackets fixedly installed at the top of the bottom turntable, with several guide wheels installed on the wheel brackets; several guide rails cooperating with the guide wheels are fixedly installed on the outer wall of the chamber cylinder; the bottom turntable is rotated by a drive structure. This utility model's soaking and washing device effectively solves many defects of traditional soaking and washing devices, such as cage soaking and washing, which suffer from poor washing effect, low washing efficiency, and the need for manual intervention due to the difficulty in fully reacting the plant tubers with the washing solvent during the washing process.
Owner:QINGYANG COUNTY HUAYAO AGRI DEV CO LTD

An anti-aging traditional Chinese medicine composition and a preparation method thereof

PendingCN122342784ABiotechnologyTelomerase
An anti-aging traditional Chinese medicine composition and its preparation method belong to the field of traditional Chinese medicine technology. The composition consists of the following components by weight: 3-60 parts of Polygonatum sibiricum, 1-70 parts of Astragalus membranaceus, 2-40 parts of Lycium barbarum, and 1-40 parts of Ganoderma lucidum spore powder. The method is as follows: soak the raw materials except for Ganoderma lucidum spore powder; decoct the raw materials 1-3 times; combine the decoctions obtained after several decoctions and concentrate them to obtain concentrated decoction; prepare the concentrated decoction into freeze-dried powder; add Ganoderma lucidum spore powder to the freeze-dried powder and stir evenly. The pharmacodynamic research results of the anti-aging of the present invention are as follows: (1) The test drug can significantly prolong the average lifespan of naturally aging nematodes by 30%, which is better than Erjingwan and the Western medicine NMN; (2) improve exercise, feeding ability and nervous system function; (3) improve antioxidant capacity: reduce the fluorescence intensity of ROS and lipofuscin, and improve the survival rate of nematodes after H2O2 stress stimulation; (4) improve telomerase activity; (5) improve cognitive dysfunction and learning and memory ability.
Owner:HARBIN MEDICAL UNIVERSITY

Ultrasonic-assisted osmosis extraction method of wine prepared rhizoma polygonati tablets

This invention discloses an ultrasonic-assisted percolation extraction method for processed Polygonatum sibiricum tablets, relating to the field of percolation extraction of processed Polygonatum sibiricum tablets. This ultrasonic-assisted percolation extraction method for processed Polygonatum sibiricum tablets involves careful selection and intermittent pulverization to a specific particle size during pretreatment, ensuring uniform particle size and facilitating the full release of active ingredients. In establishing the percolation system, the concentration and amount of ethanol solution are precisely controlled, and it is slowly added with stirring and allowed to stand, allowing the Polygonatum sibiricum particles to be fully impregnated. The ultrasonic-assisted treatment is intermittent, with a specific frequency and power set, utilizing cavitation and other effects to promote the release of active ingredients while avoiding continuous action that could damage them. The temperature is precisely controlled at 30-40℃ to prevent high temperatures from damaging heat-sensitive components. These measures work together to effectively improve the extraction efficiency and quality of the active ingredients in Polygonatum sibiricum, reduce the loss of active ingredients, and ensure the integrity and high quality of the extract.
Owner:TIBET MILIN TIBETAN MEDICINE VALLEY PHARMACEUTICAL CO LTD +2