554 results about "Polygonatum sibiricum" patented technology

The invention relates to the field of biological medicine, and discloses a rhizoma polygonati-fructus lycii heterozygous exosome, a preparation method and application thereof and an antioxidant composition. The hybrid exosome comprises miRNA-156a (micro Ribonucleic Acid) and miRNA-396b (micro Ribonucleic Acid), and the expression quantity ratio of the miRNA-156a to the miRNA-396b is (1.2 to 1.8): 1; the heterozygous exosome is loaded with a polygonatum kingianum characteristic active component and a Chinese wolfberry fruit characteristic active component. The rhizoma polygonati-fructus lycii heterozygous exosome is good in biocompatibility and capable of remarkably improving the cell survival rate, and brand-new and efficient raw materials and technical supports are provided for development of anti-aging and anti-oxidation functional products.

The invention discloses bird's nest composite honey suitable for women. The bird's nest composite honey is prepared from the following raw materials in parts by weight: 1-10 parts of bird's nests, 1-10 parts of ginseng, 1-10 parts of donkey-hide gelatin, 1-10 parts of lucid ganoderma, 1-10 parts of walnuts, 5-50 parts of rhizoma polygonati, 5-50 parts of fingered citron, 5-50 parts of dried orange peel, 5-50 parts of dried ginger, 5-50 parts of raw malt and 700-970 parts of refined brown sugar. The cubilose composite honey suitable for women is prepared by taking refined brown sugar as a main raw material and combining more than ten precious traditional Chinese medicinal materials such as cubilose, ginseng, donkey-hide gelatin, lucid ganoderma, walnuts, rhizoma polygonati, fingered citron, dried tangerine or orange peel, dried ginger and raw malt, has the characteristics of being good in taste, quick to dissolve, easy to absorb, pure in color and luster, sweet and lingering, simple and convenient to brew one cup of one piece of sugar; the traditional Chinese medicine composition is suitable for women with yellow, dark and blood-free faces and less menstruation, can maintain beauty, keep young and improve menstruation, and has an obvious menstruation continuing effect on menopausal groups.

The invention discloses fertilization cultivation equipment for polygonatum odoratum breeding, and relates to the technical field of fertilization cultivation. Comprising a circular plate, the bottom of the circular plate is fixedly connected with a motor, the output end of the motor penetrates through the circular plate, the side, close to a body, of the top of the circular plate is fixedly connected with a protection plate, the top of the circular plate is slidably connected with two arc plates, the end, away from the protection plate, of each arc plate is fixedly connected with a side plate, and the two arc plates are symmetrically arranged with the protection plate as the center; the bottom of the bent plate is in contact with the top of the circular plate. According to the fertilizing cultivation equipment for polygonatum odoratum breeding, the rotating shaft drives the bent plate to rotate, at the moment, fertilizer on the round plate is thrown out under the action of centrifugal force under the rotation of the bent plate, and therefore a large area can be covered, fertilizing dead angles are reduced, meanwhile, fertilizer distribution can be accurately controlled, fertilizer distribution in the field is more uniform, and the fertilizing effect is better. And the overall growth quality and yield of crops can be improved.

The invention relates to the technical field of functional product preparation, and provides a rhizoma polygonati and saussurea involucrata bone marrow peptide tablet as well as a preparation method and application thereof. The rhizoma polygonati and saussurea involucrata bone marrow peptide tablet is prepared from the following components: collagen peptide powder, L-isoleucine, a compound nutrient supplement, rhizoma polygonati, sorbitol, yak bone marrow peptide powder, fructus phyllanthi, fructus alpiniae oxyphyllae, mulberry powder, a saussurea involucrata culture and magnesium stearate. All the components of the rhizoma polygonati and saussurea involucrata bone marrow peptide tablet disclosed by the invention have a synergistic effect, so that the effects of conditioning sub-health, maintaining joints and assisting in treating diseases can be achieved.

The invention discloses a medicinal and edible anti-alcoholism composition and a preparation method thereof, and relates to the crossing field of biotechnology and food and medicine, the composition comprises the following components: dried orange peel powder, vitamin C, glutathione, phellinus igniarius extract, polygonatum sibiricum extract, oriental wormwood extract, isatis root extract, schisandra chinensis extract, ginseng powder, lucid ganoderma extract and licorice extract. Silymarin, puerarin, white tomato powder, watermelon powder, fucoidin, tomato powder, mung bean powder, celery powder, turmeric powder, hawthorn fruit powder, honey powder, corn peptide, soybean peptide powder, xanthan gum and stevioside are added. The composition provided by the invention has the effect of increasing the content of ethanol dehydrogenase and acetaldehyde dehydrogenase in blood after drinking, and has the capability of promoting alcohol metabolism.

The invention provides tartary buckwheat herbal baijiu and a preparation method thereof.The method aims at solving the problems that existing tartary buckwheat baijiu is lost in active ingredient, single in flavor and unstable in baijiu body, firstly, tartary buckwheat submicron powder, radix puerariae submicron powder and rhizoma polygonati submicron powder are put into Maotai-flavor base liquor together, and two-section type closed extraction is conducted at the normal temperature and then at the low temperature, adding a part of citric acid solution to adjust the pH at the initial stage of extraction; squeezing and filtering extract liquor, immediately adding bamboo leaf extract and phytic acid to carry out synergistic anti-oxidation treatment, and carrying out short-term aging; and finally, blending with the residual base wine. According to the preparation method disclosed by the invention, the retention rate of active ingredients such as tartary buckwheat flavone and the stability of the wine body are remarkably improved through staged extraction and dual antioxidant protection, the wine body is successfully endowed with coordinated baking fragrance, sauce fragrance and herbal flavor, and the taste is mellow and mild.

The invention relates to the technical field of Chinese herbal medicine fermentation, and discloses a mixed strain fermentation method for efficient conversion of non-medicinal parts of traditional Chinese medicine, which comprises the following steps: constructing an intelligent fermentation system comprising a plurality of independent fermentation units, respectively culturing different strains such as aspergillus niger, bacillus subtilis, saccharomyces cerevisiae and the like in each fermentation unit, the online sensor is integrated in the system and used for monitoring key fermentation parameters in real time, and a fermentation model and an optimization algorithm are arranged in the system and can automatically adjust fermentation conditions. An intelligent fermentation system comprising a plurality of independent fermentation units is constructed, precise classification pretreatment and mixing according to a specific ratio are carried out on rhizoma polygonati stems and leaves and gentian stems and leaves, and an intelligent control system is utilized to dynamically regulate and control the fermentation process, so that the synergistic effect of different strains such as aspergillus niger, bacillus subtilis and saccharomyces cerevisiae is fully exerted, and the fermentation efficiency is improved. The dissolution rate and the conversion rate of active ingredients in the non-medicinal part of the traditional Chinese medicine are improved.

The invention relates to the technical field of food, in particular to a preparation method of high-polysaccharide-content fermented rhizoma polygonati capable of tonifying qi and blood, which comprises five steps of raw material treatment, extraction of small-molecular-weight nutrients, fermentation treatment, polysaccharide extraction and mixing. According to the method, low-molecular-weight nutrients and high-molecular-weight polysaccharides in rhizoma polygonati are separated, concentrated respectively and then mixed. Compared with an existing rhizoma polygonati product adopting a single raw material, the proportion of small molecular weight nutrients and polysaccharide content in the mixed powder prepared by mixing the rhizoma polygonati leaves, the rhizoma polygonati stems and the rhizoma polygonati roots is more balanced, impurities and toxic substances in rhizoma polygonati can be removed, the nutrient content is increased, the polysaccharide content is artificially controllable, and the rhizoma polygonati product has the advantages that the production cost is reduced, and the production efficiency is improved. The rhizoma polygonati product with high polysaccharide content is prepared by increasing the proportion of the polysaccharide concentrated solution.

The invention discloses a synbiotics composition with bacteriostatic and anti-inflammatory effects, which comprises probiotics and prebiotics in parts by weight, the probiotics comprise the following components in parts by weight: 0.05 to 0.15 part of freeze-dried powder of lactobacillus rhamnosus PB-LR76, 0.05 to 0.15 part of freeze-dried powder of lactobacillus acidophilus HH-LA26, 0.05 to 0.15 part of freeze-dried powder of lactobacillus bulgaricus HH-LB57, 0.05 to 0.15 part of freeze-dried powder of bifidobacterium lactis HH-BA68, 0.05 to 0.15 part of freeze-dried powder of lactobacillus reuteri PB-LR09, and 0.05 to 0.15 part of freeze-dried powder of lactobacillus plantarum HH-LP56; the prebiotics are fructo-oligosaccharide or a rhizoma polygonati extract. Compared with the single use of probiotics or prebiotics, the synbiotics composition disclosed by the invention has stronger antibacterial and anti-inflammatory effects. The invention further discloses application of the synbiotics composition in preparation of a medicine for treating enteritis.

The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition for dispelling effects of alcohol and protecting liver and application. The composition for dispelling the effects of alcohol and protecting the liver comprises the following raw materials: 1-4 parts of calculus bovis factitius, 1-4 parts of artificial bear gall, 35-55 parts of a pseudo-ginseng extract, 40-60 parts of a herba artemisiae scopariae extract, 50-70 parts of a rhizoma smilacis glabrae extract, 30-50 parts of a polygonum cuspidatum extract, 30-50 parts of a radix paeoniae alba extract, 70-90 parts of a pueraria flower extract, 40-60 parts of a rhizoma polygonati extract and 40-60 parts of a dark malt extract. And 25-35 parts of a fructus amomi extract. The hangover-alleviating and liver-protecting composition has the advantages that the hangover-alleviating and liver-protecting effects are similar to that of a positive medicine Haiwang Jinvessel for relieving rat body mass reduction caused by an acute drunkenness model, the hangover-alleviating rate within 6 hours and the liver-protecting and anti-oxidation effects are similar to that of a positive medicine Haiwang Jinvessel, the body mass improvement effect, the hangover-alleviating rate and the anti-oxidation capability of a body are better, and the hangover-alleviating and liver-protecting composition has good development and application values.

The invention discloses a traditional Chinese medicine composition for treating qi-blood deficiency type fatigue and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials: codonopsis pilosula, salvia miltiorrhiza, schisandra chinensis, radix ophiopogonis, red ginseng, rhizoma polygonati, astragalus membranaceus, spina date seed and honey-fried licorice root. Comprising the following steps: preparing radix ginseng rubra and rhizoma polygonati into medicinal powder, infiltrating with ethanol, putting into a percolator, adding ethanol to immerse the medicinal powder, percolating by taking ethanol as a solvent, filtering and collecting filtrate; mixing codonopsis pilosula, salvia miltiorrhiza, schisandra chinensis, radix ophiopogonis, astragalus membranaceus, spina date seed and honey-fried licorice root with medicine powder residues left after percolation, adding water for soaking, decocting twice, combining medicine liquid, concentrating, adding ethanol, filtering and collecting filtrate; and mixing all the filtrates, and heating to remove ethanol. The traditional Chinese medicine composition has the effects of invigorating qi and blood, nourishing yin and generating body fluid, warming and tonifying heart and spleen, and refreshing mind and restoring consciousness, is used for treating qi and blood deficiency, qi and yang deficiency, palpitation and shortness of breath, fatigue and fatigue, and neurasthenia type fatigue, and has the advantages of definite curative effect, small side effect and low price.

The utility model relates to the technical field of polygonatum sibiricum seed culture seedling transplanting, and discloses a special transplanting device for polygonatum sibiricum seed culture seedlings, which comprises a cutting frame, a cross rod fixedly mounted on one side, far away from the cutting frame, of a plug plate, a base plate fixedly welded on one side, far away from the cutting frame, of an inclined frame, and a sliding rod fixedly mounted on the outer wall of the top of the base plate. A transverse plate is fixedly mounted on the left outer wall of the plug plate, and a moving rod is fixedly welded to the top end of the annular frame. According to the special transplanting equipment for the polygonatum sibiricum cultivation seedlings, when the polygonatum sibiricum seedlings need to be transplanted, a cutting frame is arranged on the periphery of the polygonatum sibiricum seedlings in a sleeving mode, a pedal is treaded, the pedal can drive the cutting frame to move downwards, the cutting frame can go deep into soil, a cross rod is pushed, a plug plate can be driven by the cross rod to move downwards, the plug plate can go deep into the soil, and bottom plugging is completed; the problems that the bottom of a cylinder of an existing transplanting device is not provided with a shielding piece, soil in the cylinder is prone to falling off in the process that the cylinder is lifted upwards, and the survival rate of seedlings is low are solved.

The utility model belongs to the field of polygonatum sibiricum production and processing, and particularly relates to a polygonatum sibiricum production smashing device which comprises a stock bin. The top of the stock bin is fixedly connected with a crushing motor; the output end of the crushing motor is fixedly connected with a transmission shaft; a plurality of crushing cutters are fixedly connected to the transmission shaft; by arranging the crushing motor, the transmission shaft, the crushing cutter, the upper grinding seat and the lower grinding seat, rhizoma polygonati is fed from the upper part of the stock bin, then falls into the crushing cavity, is subjected to primary crushing treatment by virtue of the crushing cutter rotating at a high speed, is crushed into relatively large rhizoma polygonati particles, and then falls into the grinding cylinder below; according to the polygonatum sibiricum grinding and crushing device, the polygonatum sibiricum is ground and crushed through the upper grinding seat and the lower grinding seat, so that the overall crushing precision is improved, the uniformity of crushed particles is improved, the fineness of the particles is improved, meanwhile, large polygonatum sibiricum blocks are crushed into small particles through preliminary crushing in advance, and grinding and crushing can be conveniently carried out.

The invention discloses a preparation method and application of a medicinal and edible traditional Chinese medicine compound with an effect of treating uric acid diseases. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15 to 25 parts of semen plantaginis, 15 to 25 parts of pawpaw, 5 to 15 parts of rhizoma smilacis glabrae, 5 to 15 parts of herba portulacae, 1 to 11 parts of radix glycyrrhizae preparata, 5 to 15 parts of folium mori, 5 to 15 parts of folium perillae, 1 to 11 parts of semen pruni, 5 to 15 parts of rhizoma polygonati, 1 to 11 parts of black dates and 1 to 9 parts of mulberries. The traditional Chinese medicine compound is composed of medicinal and edible raw materials, has stable efficacy of reducing uric acid and relieving uric acid liver and kidney injury, renal fibrosis and gouty arthritis, can relieve arthrocele caused by gout, reduces the level of joint inflammatory factors and the like, and takes effect quickly. The traditional Chinese medicine composition can be used for treating hyperuricemia, uric acid nephropathy, gouty arthritis and hyperuricemia accompanying symptoms.

The invention discloses a Lactobacillus paracasei CCFM1455 strain, a polysaccharide prepared from the Lactobacillus paracasei CCFM1455 strain for promoting gastric mucosa repair and application of the Lactobacillus paracasei CCFM1455 strain in synergism with rhizoma polygonati, and belongs to the technical field of microorganisms and medicines. According to the lactobacillus paracasei CCFM1455 exopolysaccharide disclosed by the invention, by regulating an STAT3 / SOCS3 signal channel, the levels of gastric mucosal lesion markers PGE2 and TFF3 are remarkably reduced, the expression of inflammatory factors is regulated, and gastric barrier protection and inflammation relief are realized. In addition, when the strain is used for fermenting polygonatum sibiricum, double synergistic effects can be generated: (1) macromolecular substances such as polygonatum sibiricum saponin are biologically converted, and easily absorbed micromolecular active substances such as oleanolic acid and liukucoumarin are generated; (2) polygonatum polysaccharide is converted into high-activity compound polysaccharide, so that the mucous membrane repairing synergistic effect is enhanced; therefore, the lactobacillus paracasei CCFM1455 and the fermentation derivative thereof provide an innovative solution for targeted intervention of gastric mucosal lesion and modernization of traditional Chinese medicines.

The invention discloses aronia melanocarpa plant composite powder and a preparation method thereof. The aronia melanocarpa plant composite powder comprises the following raw materials in parts by weight: 40-50 parts of aronia melanocarpa powder, 15-20 parts of dihydroquercetin powder, 10-15 parts of black sesame powder, 2-5 parts of honeysuckle flower powder, 1-2 parts of dandelion powder, 0.5-2 parts of radix polygonati officinalis powder and 1-3 parts of mint powder. The problems that existing aronia melanocarpa powder is single in component and prone to functional limitation, the single aronia melanocarpa powder mainly provides anthocyanin antioxidant components and has the functions of resisting oxidation, protecting eyes and resisting inflammation, but the effect dimension is single, the health requirements of consumers for comprehensive conditioning are difficult to meet, and the single aronia melanocarpa powder is obvious in acerbity and poor in taste and has a certain health care effect are solved. The aronia melanocarpa plant composite powder compounded with functional plant components is urgently needed to solve the problem that the aronia melanocarpa plant composite powder is easy to cause taste fatigue after being drunk for a long time.

The invention provides a preparation method of probiotic fermented polygonatum sibiricum polysaccharide, and belongs to the field of traditional Chinese medicinal material processing. The preparation method comprises the following steps: (1) adding cellulase and pectinase into polygonatum kingianum, carrying out water extraction, carrying out enzyme deactivation after water extraction, and carrying out suction filtration to obtain filtrate; (2) preparing bacillus DU-106 and lactobacillus plantarum nbk-MA2 into bacterial powder, and adding water to obtain bacterial liquid; mixing the bacterial liquid with the filtrate, fermenting, performing suction filtration, and centrifuging to obtain supernate; performing alcohol precipitation to remove protein; carrying out ethanol precipitation by using absolute ethyl alcohol again, collecting the precipitate after centrifuging, and carrying out redissolution, dialysis and freeze-drying to obtain fermentation modified crude polysaccharide; and (3) purifying the fermented and modified crude polysaccharide to obtain a purified polysaccharide component. The obtained probiotic fermented polygonatum sibiricum polysaccharide has the effect of losing weight, and can obviously improve the obesity characteristics of mice, specifically, reducing body weight, reducing fat, reducing serum liver lipid level, relieving serum liver inflammation of the mice, weakening blood glucose insulin sensitivity, repairing liver injury and the like.

The utility model belongs to the technical field of cleaning devices, and particularly relates to a rhizoma polygonati production and processing cleaning device which comprises a cleaning device body. A motor and a discharging groove are installed on the side wall of the cleaning device body. The output end of the motor penetrates through the side wall of the cleaning device body and is fixedly connected with a rolling brush; the rolling brush is located in the cleaning device body. A rotating seat is fixedly connected to the top of the cleaning device body; the middle part of the rotating seat is rotationally connected with a cover plate; the inner side wall of the cover plate is fixedly connected with a water pipe; a plurality of water spraying heads are mounted in the middle of the water pipe; the end part of the water pipe is communicated and connected with a water delivery joint; the turnover cover plate is arranged at the top of the cleaning device body, so that liquid and rhizoma polygonati can splash when the rhizoma polygonati is cleaned by the cleaning device body, and the problem of loss caused by overflowing of the rhizoma polygonati is solved.

The invention belongs to the technical field of medicine, and particularly relates to polygonatum polysaccharide, a preparation method and application, the structural formula of the polygonatum polysaccharide is as follows: m1 + m2 = 11, n = 4; the rhizoma polygonati polysaccharide can relieve OS, inhibit inflammatory response, break vicious circle generated and activated by inflammation-OS-TGF-beta1 and block excessive activation and downstream signals of a key fibrosis factor TGF-beta1, so that renal dysfunction and renal fibrosis induced by adenine are remarkably improved, and the rhizoma polygonati polysaccharide has a good treatment effect on renal injury.

The present invention provides a processing method for polygonatum sibiricum, which relates to the technical field of traditional Chinese medicine processing. The processing method for polygonatum sibiricum mainly includes steps such as pre-drying polygonatum sibiricum, preliminary steaming, vacuum moistening treatment with a mixture of yellow rice wine and ice water bath, repeated steaming and sunning 3 times, pre-cooling with ice water bath, rapid cooling and placing at -80 °C, high-temperature steaming and then drying to a water content of 8% - 10%. The present invention overcomes the deficiencies of the prior art, shortens the steaming time, streamlines the processing procedures, reduces the toxicity of polygonatum sibiricum on the basis of effectively retaining the polysaccharide content in polygonatum sibiricum, improves the quality of the cut pieces, and further improves the production and processing efficiency.

The invention discloses a rapid quantitative detection method for quantitative analysis of multi-components by single marker (QAM) of a pharmaceutical composition containing three-ingredient rhizoma polygonati decoction, and belongs to the technical field of detection and analysis. Specific components of the traditional Chinese medicinal materials in the medicine composition containing the three-component rhizoma polygonati decoction are quantified, three components of the three traditional Chinese medicinal materials are quantified, and determination is carried out under two detection wavelengths in a gradient elution mode. The detection wavelength is as follows: the 5-hydroxymethylfurfural is 270nm, the quercetin-3-O-gentiobioside and the isorhamnetin-3-O-gentiobioside are 330nm, the wave crests are appropriate in size, the 5-hydroxymethylfurfural, the quercetin-3-O-gentiobioside and the isorhamnetin-3-O-gentiobioside do not interfere with each other, the quantitative analysis of multiple components by one marker is realized, and the method is simple, convenient, rapid, accurate, low in cost, high in efficiency and beneficial to market supervision.

The invention relates to the technical field of functional food, and discloses a food fermentation-based detoxifying, beautifying and antioxidant prescription and a preparation method thereof. The prescription is based on medicinal and edible plants such as black beans, red dates, mulberries, haws, Chinese wolfberry fruits, prepared rehmannia roots, rhizoma polygonati and the like; the purple cabbage powder, the pumpkin powder, the dandelion root powder, the tremella polysaccharide, the quinoa germ powder and the bamboo leaf flavonoid extract are compounded, and the lactobacillus acidophilus and the clostridium butyricum are subjected to synergistic fermentation treatment. The preparation method comprises the steps of raw material pretreatment, mixed saccharification, constant-temperature anaerobic fermentation, after-ripening, sterilization, drying forming and the like. The product is rich in polyphenols, flavonoids, short-chain fatty acids and oligosaccharides, and has remarkable functions of resisting oxidation, clearing bowels, expelling toxins, beautifying, protecting skin and regulating immunity. The optimal fermentation time is 120 hours, compared with a traditional fermentation period, the method has better polyphenol release efficiency and antioxidant activity, the process is mild, the method is suitable for preparing liquid drinks, powder or freeze-dried oral granules, the safety is high, and industrial popularization is easy.

The invention belongs to the technical field of rhizoma polygonati deep processing, and particularly relates to a rhizoma polygonati primary pulp processing technology which comprises the following steps: (1) soaking: soaking dried rhizoma polygonati slices in water for 25-35 minutes to obtain soaked rhizoma polygonati slices; (2) boiling the rhizoma polygonati slices: taking the soaked rhizoma polygonati slices and fresh tremella, adding water, boiling, keeping the boiling state for a certain time, stopping fire, and naturally cooling to obtain a mixed solution; and (3) sterilizing: filtering the mixed solution, canning, and pasteurizing to obtain the polygonatum sibiricum primary pulp. The polygonatum sibiricum primary pulp prepared by the process disclosed by the invention is harmonious and soft in taste, excellent in storage property and relatively good in DPPH free radical scavenging capability.

The invention provides a rhizoma polygonati extract as well as a preparation method and application thereof in prevention and control of glucose and lipid metabolism disorder. According to the invention, an effective component group consisting of effective parts of flavonoids and saponins is extracted from a traditional Chinese medicinal material polygonatum sibiricum, the sum of the actual contents accounts for more than 50% of the total weight of the polygonatum sibiricum extract, and meanwhile, the effective component group is used for preparing medicines for preventing and / or treating impaired glucose tolerance and glucose and lipid metabolism disorder. The traditional Chinese medicine composition is clear in curative effect, controllable in quality and easy to industrialize in preparation process, various proper dosage forms can be prepared according to clinical requirements, and a convenient, effective, stable and controllable modern traditional Chinese medicine is provided for clinical application.

The invention discloses a polygonatum sibiricum medicinal material species identification method based on a polygonatum sibiricum characteristic compound and application of the polygonatum sibiricum medicinal material species identification method. The invention discloses a polygonatum sibiricum medicinal material species identification method based on a polygonatum sibiricum characteristic compound. The method comprises the following steps: 1) preparing a polygonatum sibiricum rhizome sample solution; 2) analyzing different sealwort rhizome metabolites by liquid chromatography-mass spectrometry; and 3) discriminating the species of the rhizoma polygonati medicinal material, namely discriminating the species of the rhizoma polygonati medicinal material if the rhizoma polygonati rhizome metabolite contains a corresponding characteristic compound. The polygonatum sibiricum variety is polygonatum kingianum, polygonatum sibiricum, polygonatum cyrtonema and polygonatum odoratum. According to the application of the polygonatum kingianum characteristic compounds in polygonatum kingianum medicinal material species identification, each polygonatum kingianum species selects three representative characteristic compounds which are relatively high in content, have functional specificity representatives and are common in the market, the species of the polygonatum kingianum medicinal material can be identified as long as the three representative characteristic compounds are contained at the same time, the accuracy is high, the number of components to be detected is small, and the accuracy is high. The detection period is short.

The invention provides processed rhizoma polygonati polysaccharide, a preparation method thereof and application of the processed rhizoma polygonati polysaccharide in preparation of a medicine for treating renal injury. The nine-processed polygonatum sibiricum polysaccharide is named as NPCP and is composed of fructose and glucose, the NPCP is straight-chain inulin type polysaccharide with the polymerization degree of 12, and the structure of the NPCP is Glcp-(1-) and Fruf-(2-terminal,-1)-Fruf-(2-main chain. According to the obtained uniform nine-process polygonatum polysaccharide NPCP, the protective effect on adenine-induced HK-2 cell injury is achieved by improving the content of renal function markers, improving oxidative stress injury, reducing expression of proinflammatory cytokines, improving intestinal flora disorder and up-regulating short-chain fatty acid in the intestinal tract; more treatment directions are provided for effectively improving adenine-induced renal toxicity by the nine-process polygonatum polysaccharide, and theoretical and experimental bases are provided for clinically finding effective preparation of drugs for treating renal injury.

The invention discloses rhizoma polygonati decoction pieces and a preparation method thereof, and belongs to the technical field of rhizoma polygonati processing. The method comprises the following steps: dicing polygonatum kingianum; the diced polygonatum sibiricum is stir-fried with sand, the stir-frying temperature is 120-130 DEG C, and the stir-frying time is 8-12 minutes; pressing the diced polygonatum sibiricum through a pressing mold to obtain the diced polygonatum sibiricum with a regular shape and a hardened surface, wherein the pressing pressure is 1-2Mpa; the diced polygonatum sibiricum is put into a vacuum bag, then the vacuum bag is subjected to constant-volume freezing, the constant-volume freezing temperature is gradually reduced to-14 DEG C to-18 DEG C from 4 DEG C to 8 DEG C, and the freezing time is shorter than 20 h; taking out the diced polygonatum sibiricum from the vacuum bag, and steaming for 5-6 hours; and drying and packaging the diced polygonatum sibiricum. The polygonatum sibiricum decoction pieces are regular dices, are sweet in taste, have inherent fragrance of polygonatum sibiricum, are free of astringent taste, are soft and elastic in texture, are black and have glossy luster, the content of calcium oxalate is less than 0.1%, and the content of polygonatum sibiricum polysaccharide is more than 4.5%.

The invention relates to the technical field of biotechnology and food science, in particular to a preparation method of ganoderma lucidum exosomes containing medicinal and edible active ingredients, which comprises the following steps: culturing ganoderma lucidum mycelium fermentation liquor; adding the rhizoma polygonati solution into the ganoderma lucidum mycelium fermentation liquor, and carrying out biotransformation on a rhizoma polygonati powder substrate to obtain ganoderma lucidum exosome fermentation liquor; and separating, extracting and purifying the ganoderma lucidum exosome fermentation liquor to obtain the ganoderma lucidum exosome. The ganoderma lucidum exosome is extracted and purified, the medicine and food homology characteristic of the ganoderma lucidum exosome is fully utilized, and a new technical path is provided for development of functional food, health care products and medicines. According to the method, the corresponding exosome can be successfully extracted from the ganoderma lucidum culture solution, and the density of the exosome extracted after the polygonatum sibiricum is added is obviously higher than that of the exosome extracted without the polygonatum sibiricum, that is, after the polygonatum sibiricum is added, the active ingredients of the polygonatum sibiricum permeate into the original ganoderma lucidum exosome, and the ganoderma lucidum exosome has an obvious killing effect on cancer cells and shows a stronger killing effect.

The invention discloses a processing method of wine-processed rhizoma polygonati, which belongs to the technical field of traditional Chinese medicine processing, and comprises the following steps: selecting rhizoma polygonati, cleaning, slicing and drying; spraying an acidic compound solution, steaming for the first time, preserving heat, moistening, and collecting a steaming solution; after finishing and slicing, spraying catalytic compound liquid prepared from steaming liquid and auxiliary materials, steaming for the second time, and preserving heat and moistening; then steaming at normal pressure for the third time; and finally, pre-drying at low temperature, heating and finally drying, and inspecting to obtain a wine rhizoma polygonati finished product. According to the invention, a segmented precise regulation and control system is constructed, so that the used functional additive can be completely removed, and the purity and safety of the product are guaranteed; the compound liquid proportion, spraying parameters and steaming key indexes are defined, systematic control standards are formed, the problem of quality fluctuation of traditional processing is solved, the product appearance and taste are better, the key indexes stably exceed the pharmacopoeia standard, and upgrading from experience and technology to standardized production is achieved.

The invention discloses a radix astragali, rhizoma polygonati and ligustrum lucidum ait traditional Chinese medicine preparation for treating myelosuppression as well as a preparation method and a detection method thereof. The preparation is prepared from 50-150 parts of radix astragali, 50-150 parts of wine-processed rhizoma polygonati, 25-75 parts of wine-processed ligustrum lucidum ait, 50-150 parts of blanched rhizoma drynariae, 50-150 parts of radix trichosanthis and 25-75 parts of herba epimedii. The optimal extraction process and refining process are screened out based on effective components and pharmacological activity through a large number of tests, and the optimal preparation process of the Shuanghuangliangwhitening oral liquid and other traditional Chinese medicine preparations is obtained through stability investigation and verification. According to the invention, a thin layer chromatography is adopted, the four medicinal materials of astragalus membranaceus, glossy privet fruit, rhizoma drynariae and herba epimedii are respectively subjected to thin layer chromatography research, and methodology research shows that the method is stable and feasible. The invention establishes a content determination method for astragaloside, calycosin-7-glucoside, specnuezhenide and icariin, establishes a quality standard, and has important significance for ensuring the clinical curative effect and safety of astragaloside, calycosin-7-glucoside, specnuezhenide and icariin.