178 results about "Synbiotics" patented technology

The invention relates to a probiotic combination comprising different combinations of lactobacilli. propionic acid bacteria and / or bifidobacteria. The probiotics are preferably combined with a suitable prebiotic to form a synbiotic. The combination of the invention can be consumed as such or combined with a suitable foodstuff or pharmaceutical product, and it is therapeutically useful for example for stimulating the immune system and for general health improvement.

A novel product comprising a mixture of probiotic and prebiotic ingredients for the treatment of IBS, IBD, Crohn's disease, antibiotic induced diarrhea and other bowel disorders is described herein. Stabilized rice bran derivatives, including stabilized rice bran, RiSolubles, RiceMucil, and Cea100, are used as the source of prebiotics. The prebiotic source is not only rich in fructo-oligosaccharides, but also has potent antioxidants and phytonutrients for intestinal health and the proliferation of bifido-bacteria in the intestines. The probiotics used are different combinations and concentrations of Lactobacilli species, depending on the specific gastrointestinal disease which is targeted. When refrigerated, the products are shelf-stable (95-99%) for at least one year.

The invention discloses an infant milk power added with synbiotics, comprising the following components: fresh milk 40-68 gram; demineralized whey powder 15-34 gram; granulated sugar3-6 graml; vegetable oil 4-8 gram; compound prebiotics 0.4-20 gram; compound probiotic 1.0*10<5>-1.0*10<11> cfu. The inventive infant milk power can be ysed for building advantages of beneficial bacterium when a newborn infant starts colony valuation. Through adding probiotic, the number of probiotic is advanced to increase in a short time, through adding prebiotics having selectively increasing effect on probiotic, the added probiotic is performed with fast field setting, thereby maintaining advantages of probiotic in intestinal flora. The invention also markedly relieves diarrhoetic symptoms, and has definite treatment effect on diarrhea caused by rotavirus.

This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1β1,4G1c and Ga1β1,6Ga1NAcα1,3Ga1β1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1β1,6Ga1, Ga1β1,6Ga1β1,4G1c Ga1β1,6Ga1β1,6G1c, Ga1β1,3Ga1β1,3G1c, Ga1β1,3Ga1β1,4G1c, Ga1β 1,6Ga1β 1,6Ga1β 1,4G1c, Ga1β 1,6Ga1β 1,3Ga1β 1,4GIc Ga1β 1,3Ga1β 1,6Ga1β 1,4GIc and Ga1β1,3Ga1β1,3Ga1β1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1β1,4G1c and NeuAcα2,6Ga1β1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.

The invention relates to a micro-ecological regulator, which belongs to the category of micro-ecological preparations. The product contains Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium adolesentis, lactobacillus acidophilus, fructo-oligosaccharides, galacto-oligosaccharides, vitamins and the like. A concrete production process comprises the following steps: 1. bacterial strains are respectively or jointly subjected to liquid deep high-density cultu, so as to obtain fermentation liquid; 2. after the fermentation liquid is centrifuged, bacterial sludge is collected, added to protective agents and made into freeze-dried powder; 3. the freeze-dried powder is added to microcapsule materials and made into microcapsules through air suspension treatment; and 4. the microcapsules are mixed with oligosaccharides, vitamins and the like and then are made into a synbiotics pharmaceutical composition. By directly replenishing human intestines with Bifidobacterium and lactobacillus acidophilus, and by simultaneously providing prebiotics for ensuring that beneficial bacteria after entering intestines can be activated rapidly and proliferate, the product adjusts and improves intestinal micro-ecosystem, so as to achieve the aims of regulating organism immunity, delaying senility, inhibiting tumors, regulating blood lipid and improving intestines and stomach. A preparation method of the product can solve the technical problem that the prior probiotics medicine is difficult to keep the stability of probiotics at normal temperature and unstable under acidic conditions, and provides a pharmaceutical composition which can be stably stored at normal temperature.

The invention provides a novel safe biological feed which comprises basic ration, sodium humate, montmorillonite and synbiotics. To feed the livestock and poultry with the novel safe biological feed of the invention can reduce the condensation of ammonia gas in animal houses and improve cultivation environment, meanwhile, the invention enhances the immunity of animal organism, keeps balance of intestinal flora of the livestock and poultry to avoid diarrhea and dysentery and advances the feed conversion ratio and egg production rate.

The invention relates to a synbiotics of bacillus licheniformis and oligosaccharide class prebiotics and a composite and a formulation thereof, being characterized in that the synbiotics comprises bacillus licheniformis medical live bacterial powder and the oligosaccharide class prebiotics, wherein the bacillus licheniformis medical live bacterial powder contains live bacteria about 30 billion / gram; the weight ratio of the bacillus licheniformis medical live bacterial powder to the oligosaccharide class prebiotics is 1:1 to 76; the weight ratio of the medical live bacterial powder of the composite, the oligosaccharide class prebiotics and auxiliary materials is as follows: 1.25-5 percent of the bacillus licheniformis medical live bacterial powder, 5-95 percent of the oligosaccharide class prebiotics, 20-50 percent of preferable oligosaccharide class prebiotics, 30-65 percent of diluting agents, 1-20 percent of bonding agents, 1-15 percent of disintegrating agents, 0.1-3 percent of lubricating agents, 1-10 percent of coating agents, 0.01-0.1 percent of flavoring agents, 0.0001-0.001 percent of coloring agents, and 0.1-15 percent of suspending agents. The synbiotics composite is prepared into oral common tablets, oral cavity disintegration tablets, dispersing tablets, enteric-coated tablets, granular formulation, enteric-coated granular formulation, capsules, enteric-coated capsules, dry supensoid agents and external tablets according to a conventional process; and an in vitro test shows that each formulation can promote the growth and the reproduction of the synbiotics of bacillus licheniformis, restrain the growth of harmful bacteria, enhance the immunizing power of parasitifers, reduce diarrhea and enhance the health care.

The invention provides a method for preparing edible bacteria synbiotic microcapsules. The method comprises the following steps: firstly, zymotic fluids of four strains of probiotic bacteria, namely Lactobacillus acidophilus, lactobacillus plantarum, lactobacillus casei and lactobacillus rhamnosus are prepared, then supernatants are removed after the speed of 5000r / min, and bacterial sludges are embedded for standby. 10g of each bacterial sludge of the probiotic bacteria to be embedded and 4g of edible bacteria Agaricus blazei powder with the fineness of 200 meshes are mixed with 40g of mixed colloid containing 2.5 percent of sodium alginate and 0.5 percent of flaxseed gum respectively; the first stirring is performed for 20min at a rotating speed of 200 r / min; the mixture is poured into a triangular flask which contains 1.5 times of volume of edible oil; the second stirring is performed for 20min at a rotating speed of 400r / min; a 1.5 percent CaCl2 solution is added into the mixture to be calcified for 3h; sterilized physiological saline is used to wash gel beads for three times; the gel beads are placed into a 0.6 percent chitosan solution with a pH value of 5.5 to perform a film-forming reaction for 15min, taken out, washed by the sterilized physiological saline and then placed into a citric acid solution with the concentration of 55mM to be liquefied for 30min; and wet microcapsules are obtained after the washing of the sterilized physiological saline, collected by centrifugating for 10min at a rotating speed of 150r / min, precooled, and finally freeze-dried to obtain the microcapsules.

The present invention discloses a synbiotics feed additive, which is mixed and made by the useful viable, APS, non-digest oligosaccharide and the carrier according to a certain proportion. The present invention has the highlight advantages that the feed additive comprises many compositions which are useful for intestinal health and contains plant polysaccharides; which can effectively replace the antibiotics, compared with antibiotic, which is non-toxic, non-drug residues and beneficial for the health of animal and human, using the addictive can promote animal growth, improve feed conversion efficiency and reduce the incidence of disease.

The present invention relates to characterizing changes in mammalian microbiota associated with antibiotic treatments and various immunological conditions and related therapeutic methods. Therapeutic methods of the invention involve the use of probiotics, prebiotics, synbiotics, and antibiotics.

The invention relates to a milk replacer for piglets. The milk replacer contains the following components: non-active whole milk soybean meal, puffed rice, whole milk powder, whey powder, glucose, water-soluble fat powder, lysine, methionine, threonine, composite minerals, composite vitamins, a compound enzyme preparation, synbiotics and plant extracts. Experimental results show that the milk replacer provided by the invention can compensate for the lack of breast milk for piglets, improve the growth and health of piglets, improve ingestion level of weaning piglets and alleviate the weaning stress of piglets.

The invention discloses a high-protein-content growth-promoting environment-friendly fish feed. The high-protein-content growth-promoting environment-friendly fish feed comprises the following raw materials: bean cakes, cotton meal, corns, bran, fish meal, rapeseed cakes, spirulina powder, seaweed powder, wheat middling, polygonatum sibiricum powder, fish oil, calcium lactate, calcium dihydrogen phosphate, lysine, methionine, aspartic acid, glutamic acid, a vitamin mixture, minerals, phytase, synbiotics, a traditional Chinese medicine compound additive and a food attractant. The high-protein-content growth-promoting environment-friendly fish feed is rich in nutrition, and rich in contents of proteins, amino acids, vitamins, probiotics and growth substances; thus, the high-protein-content growth-promoting environment-friendly fish feed is capable of effectively promoting growths and breeding of the fishes, and improves yields and qualities of the fishes.

The use of a probiotic strain of Lactobacillus rhamnosus and an oligosaccharide mixture which comprises 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising GalNAcα1,3Galβ1,4Glc and Galβ1,6GalNAcα1,3Galβ1,4Glc, 20-90 wt % of at least one neutral oligosaccharide selected from the group comprising Galβ1,6Gal, Galβ1,6Galβ1,4Glc Galβ1,6Galβ1,6Glc, Galβ1,3Galβ1,3Glc, Galβ 1,3Galβ 1,4GIc, Galβ 1,6Galβ 1,6Galβ 1,4GIc, Galβ 1,6Galβ 1,3Galβ 1,4GIc Galβ1,3Galβ1,6Galβ1,4Glc and Galβ1,3Galβ1,3Galβ1, 4GIc and 5-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Galβ1,4GIc and NeuAcα2,6Galβ1,4Glc in the manufacture of a medicament or therapeutic nutritional composition for promoting the development of an early bifidogenic intestinal microbiota in infants delivered by caesarean section is disclosed.

The invention discloses a growth promotion feed capable of improving the immunity of freshwater shrimps. The feed is prepared from, by weight, 20-40 parts of fish meal, 5-15 parts of bean pulp, 1-5 parts of shrimp shell powder, 1-3 parts of stillage, 2-5 parts of rapeseed meal, 3-6 parts of flour, 1-4 parts of soybean phospholipid, 3-4 parts of choline chloride, 2-4 parts of shelling agent, 1-3 parts of vitamin premix, 2-5 parts of sodium humate, 1-4 parts of betaine, 3-5 parts of L-carnitine, 0.5-1.5 parts of olaquindox, 2-4 parts of fluorite powder, 1-3 parts of cellulose, 2-4 parts of attapulgite, 3-6 parts of compound traditional Chinese medicine, 1-4 parts of synbiotics and 2-5 parts of complex enzyme preparation. By the adoption of the feed, the immunity of freshwater shrimps can be effectively improved, growth of freshwater shrimps can be promoted, and the yield and quality of freshwater shrimps are effectively improved.

The invention discloses a compound synbiotic microecological preparation and a preparation method thereof. Probiotics (freeze-dried powder) and prebiotics in the weight ratio being 1:(1-5) are mixed; intestinal tract probiotics are screened out in different environments, the best strain is screened out by comparing the functions and biological characteristics of the screened intestinal tract probiotics and comparing change of viable count of the probiotics in the simulated intestinal tract environment, the content of each type of oligosaccharide is measured, the best addition amount is selected, the intestinal tract probiotics and oligosaccharide are mixed, and the compound synbiotic microecological preparation is prepared. The compound synbiotic microecological preparation can adjust microorganism balance of intestinal tracts of animals, maintain health of the intestinal tracts, stimulate growth of useful bacterial colonies and competitively inhibit harmful bacteria and finally achieves the purposes of promoting growth of the animals and improving the immunity of the animals, the obtained strain can be directly applied to preparation of the microecological preparation, and no pollution or residues are produced.

This invention relates to a preparation comprising a probiotic bacterial strain and a prebiotic mixture comprising 5-70 wt % of at least one N-acetylated oligosaccharide selected from the group comprising Ga1NAcα1,3Ga1β1,4G1c and Ga1β1,6Ga1NAcα1,3Ga1β1,4G1c, 20-95 wt % of at least one neutral oligosaccharide selected from the group comprising Ga1β1,6Ga1, Ga1β1,6Ga1β1,4G1c Ga1β1,6Ga1β1,6G1c, Ga1β1,3Ga1β1,3G1c, Ga1β1,3Ga1β1,4G1c, Ga1β 1,6Ga1β 1,6Ga1β 1,4GIc, Ga1β 1,6Ga1β 1,3Ga1β 1,4GIc Ga1β 1,3Ga1β 1,6Ga1β 1,4GIc and Ga1β1,3Ga1β1,3Ga1β1,4G1c and 2-50 wt % of at least one sialylated oligosaccharide selected from the group comprising NeuAcα2,3Ga1β1,4G1c and NeuAcα2,6Ga1β1,4G1c. The invention extends to food products comprising said preparation and to the use of the preparation in the prevention and treatment of infections.

The invention discloses a biological deodorant for animal feeding and belongs to the field of feed additives. The biological deodorant for animal feeding is composed of an active ingredient and an auxiliary protection carrier, wherein the active ingredient comprises synbiotics, the weight proportion of the synbiotics to the auxiliary protection carrier is (25-35): (50-65), the synbiotics are compounds of probiotics and prebiotics, and the mass fractions of the probiotics and the prebiotics are 65-80% and 20-35% respectively. After the biological deodorant for the animal feeding is used for feeding animals, all the active ingredients are synergistic in animal intestinal tracts, and finally the aim of reducing or eliminating odour of animal excrements is foundationally achieved, so that the biological deodorant for the animal feeding has good popularization and application values.

The invention provides a forage symbiotics mild production method used for producing saccharomyces cerevisiae cells with broken-down walls, wherein a product of the forage symbiotics mild production method comprises yeast metabolites such as yeast protein, yeast steroid, yeast polysaccharide, and yeast nucleic acid. The saccharomyces cerevisiae cells with broken-down walls can be used a novel forage additive so as to solve problems of low protein utilization ratio, high diarrhea ratio, and high morbidity in the field of animal husbandry. According to the forage symbiotics mild production method, yeast bacteria are obtained via submerged liquid state fermentation, and then the saccharomyces cerevisiae cells with broken-down walls are obtained via three-step enzymatic hydrolysis method. Production cost is low, viable count is high, and the saccharomyces cerevisiae cells with broken-down walls is a green forage additive with stability and high efficiency. Process route is disclosed in a attached figure.

The invention discloses a compound synbiotics preparation and its application. The compound synbiotics preparation includes composite Probiotics and Prebiotics, the composite Probiotics comprise Bacillus subtilis and Bacillus licheniformis, the Prebiotics are anyone of yeast cell wall polysaccharides, mannan oligosaccharides, fructo-oligosaccharides, soybean oligosaccharides, isomalto oligosaccharides, lactosucrose, galactooligosaccharides, sucrose thermal oligosaccharides caramel and oligonucleotides xylose; and the survival rate of spores is higher than 90% after the mixing granulation of the compound synbiotics preparation and a feed, and the total number of live bacteria is 1.0*10<9>-1.0*10<11>CFU / g. By utilizing the cooperative effect of different Probiotics and Prebiotics, the compound synbiotics preparation avoids the disadvantages of single Probiotics, increases the content of the Probiotics, reduces the competitor rate, improves the heat resistance and the storability of the synbiotics, improves the quality of feeding synbiotics, and has a wide application prospect.

This invention relates to a preparation comprising N-acetyl-lactosamine and / or an oligosaccharide containing N-acetyl-lactosamine and a probiotic Lactobacillus sp. The invention extends to nutritional compositions comprising said preparation and to the use of the preparation in the prevention and treatment of pathogenic infections of the gastro-intestinal and upper respiratory tracts.

The invention discloses digestion promoting mandarin fish feed with a disease resisting effect. The feed is prepared from fish meal, soybean meal, rapeseed meal, cottonseed meal, peanut meal, middling flour, prawn powder, blood worm powder, zeolite powder, alfalfa meal, bone meal, monopotassium phosphate, table salt, shrimp bran powder, cod-liver oil, palm oil, modified soybean phosphate, Vc-polyphosphoester, yeast powder, shrimp shell meal, an adhesive, choline chloride, mercaptamine, citric acid, taurine, flavomycin, saccharicterpenin, Chinese herbal medicine disease prevention additives, phagostimulant, a complex enzyme preparation and synbiotics. The mandarin fish feed can promote digestion of mandarin fish and improve the disease resistance of the mandarin fish.

The invention discloses a pregnant pig feed formula. The pig feed formula for pig from pregnant early insemination to 84 days after pregnancy comprises the following components in percentage by weight: 49% of corn, 20% of bean pulp, 2% of soybean oil, 25% of wheat bran and 4% of Muzhumei, and in addition, 200g of synbiotics and 500g of oligosaccharide are added into each ton of pig feed. The pig feed formula from 84 days after pregnancy to seven days before parturition comprises the following components in percentage by weight: 52.9% of corn, 7.5% of bean pulp, 16.5% of puffing soybean, 2.5% of imported fish meal (comprising 65% of protein), 16.5% of soybean oil, 0.1% of brown sugar (or glucose) and 4% of Muzhumei, and 200g of synbiotics and 500g of oligosaccharide are added into each ton of pig feed. The pregnant pig feed formula disclosed by the invention has obvious sweet taste if compared with the common feed, the taste and the appetite of the pregnant pig can be increased, feed use ratio is improved, the immunity, the antibiosis capability and adsorption of a pig organism can be effectively increased, morbidity is increased, and ecological environment is improved.

The invention discloses middle age and elder milk powder added with synbiotics, which contains 35-65g of fresh milk (converted to dry matter), 12-32g of desalted whey powder, 2-6g of granulated sugar, 3-8g of vegetable oil, 0.4-2g of composite Prebiotics and 1.0*10<5>-1*10<11> of composite probiotics. The milk powder of the present invention can increase quantity of beneficial bacteria for middle age and elder, thereby promoting establishment of beneficial bacteria advantage. By adding probiotics, quantity of beneficial bacteria is increased in short time; by adding Prebiotics having selectivity increment effect to probiotics, added probiotics can fast colonize and advantage of beneficial bacteria in intestinal tract flora is maintained. The milk powder of the present invention can increase absorptivity and retention rate of calcium, is added with composite vitamin, composite mineral matter and other nutrients, and can provide comprehensive nutrition for middle age and elder.

The invention discloses a synbiotic liquid goat's milk drink and a preparation method thereof, comprising 35-50 parts of synbiotic sour goat's milk, 5-10 parts of sucrose, and 0.15-0.5 parts of a stabilizer in parts by mass; 38-60 parts of water; the synbiotic yogurt goat milk is to add 2-5.5% probiotics and 0.1-2.5% prebiotics by mass to goat milk or goat milk reconstituted milk, and carry out anaerobic treatment for 5-18 hours. fermentation. Synbiotic sour goat milk is fermented with a probiotic after adding oligosaccharides and prebiotics; probiotics have a great effect on improving the microenvironment of probiotics in the human intestinal tract and promoting human health; adding oligosaccharides promotes probiotics The growth of goat milk not only retains the nutritional value and unique flavor of goat milk, but also strengthens the functional properties of oligosaccharides.

The invention discloses probiotics for preventing and treating pet diarrhea and a preparation method thereof. The probiotics contain enterococcus faecium, enterococcus faecalis, lactobacillus acidophilus, bacillus natto, saccharomyces cerevisiae and oligosaccharide, wherein the quantity ratio of the five live probiotic bacteria is (5-3):(5-3):(4-1):(4-1):(3-1). The ratio of aerobic bacteria to anaerobic bacteria is considered on the basis of adding pet advantage bacteria in the gut and 'synbiotics' theory, and the probiotics have an obvious prevention effect on pet diarrhea.

The invention provides a synbiotics feed additive special for piglets. The additive comprises Lactobacillus plantarum ZLP001 with the preservation number being CGMCC NO.7370, and fructo-oligosaccharide. According to the additive, the Lactobacillus plantarum ZLP001 and the fructo-oligosaccharide are combined, the optimized weight ratio of the Lactobacillus plantarum ZLP001 and the fructo-oligosaccharide is selected, namely the best synergy compatibility effects of the two annexing agents can be played, the effects generated by the common use of the two annexing agents are higher than those generated by single use of the two annexing agents. The additive can be widely popularized and applied in the field of livestock culture industry and has good market effects and social effects.

The invention relates to nutritional compositions with Bifidobacterium breve and non-digestible oligosaccharides selected from the group consisting of fructo-oligosaccharides, galacto-oligosaccharides, gluco-oligosaccharides, arabino-oligosaccharides, mannan-oligosaccharides, xylo-oligosaccharides, fuco-oligosaccharides, arabinogalacto-oligosaccharides, glucomanno-oligosaccharides, galactomanno-oligosaccharides, sialic acid comprising oligosaccharides and uronic acid oligosaccharides for use in improving cognitive or behavioral performance, cognitive or behavioral development, social interaction and / or neuroinflammation in infants or toddlers. Also claimed is the use of a nutritional compositions including Bifidobacterium breve, at least one non digestible oligosaccharide, glutamine in the form of free amino acids and / or glutamine containing dipeptide and / or glutaime containing tripeptide and LC-PUFA in the form or arachidonic acid and / or docosahexaenoic acid. Also claimed is a kit of parts comprising a first container comprising glutamine, and a non-digestible oligosaccharide and a second container comprising Bifidobacterium breve.

The invention discloses a synbiotic for improving the lactation and producing effect of sows, and a feeding method and application thereof. According to the synbiotic for improving the feeding effect of sows, the combination of probiotics and traditional Chinese medicine prebiotics synergistic agent is adopted. The influence of the combination of Chinese herbal medicines and bacterial powder obtained by the enlarge cultivation of lactic acid bacteria, bacillus subtilis and yeast and the like on the lactation and producing effect of sows is discussed. An experimental result shows that compared with a control group, an interval between ablactation and oestrus is shortened by 3.42 days in a synbiotic group; the fertilization rate during an oestrus period is 100% in the synbiotic group and is improved by 12.1% compared with the control group; the number of living piglets is eleven point one and is increased by zero point six compared with the control group; the weaning weight of each piglet is 9.7kg and is increased by 22.32% compared with the control group; the weaning survival rate of the piglets is 100% and is improved by 19% compared with the control group. Therefore, the lactation and producing effect of the sows are improved by feeding the synbiotic.

The invention discloses synbiotics comprising prebiotics and probiotics; the prebiotics are a combination of arbitrary one or more of galactooligosaccharide, xylooligosaccharide and oligofructose; the probiotics are a combination of arbitrary one or more of lactobacillus acidophilus, bifidobacterium longum, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus fermentium, streptococcus thermophilus and lactobacillus helveticus. The invention also discloses a preparation method of the synbiotics. Compared with the prior art, the synbiotics can effectively adjust intestinal flora of a human body, can adjust constipation and diarrhea in a dual-directional manner, and cannot produce drug dependence. Meanwhile, the method has the advantages of simple process, low cost and easy industrial promotion.