523 results about "Substance use" patented technology

An apparatus is provided for use in conjunction with a drug delivered to a gastrointestinal (GI) tract of a subject. The apparatus includes an ingestible capsule, which includes one or more electrodes, and a control component, adapted to drive the electrodes to apply an electrical current that induces local delivery of the drug in target tissue of the GI tract. Additional embodiments are also described.

The invention encompasses a method of conducting a clinical trial of a test substance from a primary site, via the internet. The internet is used in various phases of a clinical trial, including: recruiting and screening for candidates who are eligible to participate in a clinical trial of a test substance using the internet; obtaining, directly from a participant at a remote site, personal information as well as information allowing a determination of any effect(s) of the test substance on the participant after use (e.g., by evaluation forms completed and transmitted over the internet); compiling data from multiple participants.

The present disclosure relates to novel dosage forms, drug delivery regimens, methods and pharmaceutical compositions which optimize the therapeutic effects of active therapeutic substances through the application of the concept of uneven dosing.

The present disclosure relates to novel dosage forms, drug delivery regimens, methods and pharmaceutical compositions which optimize the therapeutic effects of active therapeutic substances through the application of the concept of uneven dosing.

To provide An electrode for a dielectrophoretic apparatus in which a background detected by reflecting an excited light on an electrode present under the substance (molecule) is reduced and an S / N ratio is enhanced. Also, there is provided an dielectrophoretic apparatus, in an apparatus in which a liquid containing substances to be separated is present in a non-uniform electric field formed by a dielectrophoretic electrode, and separation is carried out by a dielectrophoretic force exerting on the substances, wherein the collecting ability of substances is enhanced. The present invention is characterized in that a vacant space is provided in an electrode whereby substances subjected to influence by a negative dielectrophoretic force can be concentrated in said vacant space of an electrode, or above or below portion of the space.

The invention relates the multicomponent mixed working substance used for preparing dual-temperature by single-machine vapor compression refrigerator. The low temperature is between -60- -40Deg.C and the high temperature is between -25- 10Deg.C. The multicomponent mixed working substance comprises lower boiling working substance and high boiling working substance. The lower boiling working substance comprises tetrafluoromethane, ethylene, ethane, fluoroethylene, trifluoromethane, fluoromethane, hydrofluoeic ether, carbon dioxide, difluoromethane and penfluoroethane; the high boiling working substance comprises trifluoro-thane, hydrofluoeic ether, propylene, propane, perfluoropropylamine, propadiene, cyclopropane, difluo-monochloromethane, penta-monochloroethane, perfluoroethane, difluoroethane, isobutene, butane, butylenes, isobutylene, sevofluoropropane, hexafluoropropane, penfluoropropane and tetrachloromonofluoroethane.

A system for treating a substance using a storage vessel and two or more devices disposed in a top of the storage vessel. Each device has: (a) a volute or cyclone head, (b) a throat connected to the volute or cyclone head, (c) a parabolic reflector connected to the throat, (d) a first wave energy source comprising a first electrode within the volute or cyclone head that extends through the outlet into the opening of the throat along the central axis, and a second electrode extending into the parabolic reflector and spaced apart and axially aligned with first electrode, and (e) a second wave energy source disposed inside the throat, embedded within the throat or disposed around the throat. The substance is supplied to the inlet of the volute or cyclone head and is irradiated with one or more wave energies produced by the first and second wave energy sources.

The invention provides a sodium ion secondary battery, and a layered manganese-containing oxide active substance and an anode active substance used in the sodium ion secondary battery; the chemical general formula of the anode active substance is Na[x]A[y]Mn[1-y]O[2], wherein A is one or more selected from a group including Li, Mg, Cu, Zn, Al, V and Fe; x is more than 0.4 and less than 0.9, y is more than 0.05 and less than 0.5, delta is more than minus 0.1 and less than 0.1. Average working voltage of the anode active substance of the sodium ion secondary battery disclosed by the invention in the sodium ion secondary battery is 2.6-3.8V; furthermore, a novel anode material of layered doped manganese oxide disclosed by the invention is good in safety performance, low in cost and good in cycling stability.

A process for electrolyzing an aqueous solution of hydrochloric acid to chlorine in an electrochemical cell provided with an anode compartment and a cathode compartment including at least one gas diffusion cathode comprising an electrically conductive web provided on at least one side thereof with a coating of a catalyst for the electroreduction of oxygen comprising rhodium sulfide and optionally containing at least one fluorinated binder incorporated therein, comprising introducing aqueous hydrochloric acid containing contaminant species into the anode compartment and oxygen into the cathode compartment while impressing a direct electric current on the cell.

A process for the removal of at least one volatile compound from a reactive or unreactive mixture of substances with the aid of at least one micro-evaporator, the micro-evaporator displaying channels for carrying the mixture of substances having a hydraulic diameter of 5 to 1000 μm and a specific evaporator surface area of at least 103 m2 / m3.

The present invention relates to water soluble magnetic nanocomposite using an amphiphilic compound. Specifically, the present invention relates to water soluble magnetic nanocomposite which may be not only used as a contrast agent for magnetic resonance imaging (MRI), an intelligent contrast agent for diagnosing cancer characterized by binding a tissue-specific binder ingredient, a drug delivery system for simultaneous diagnosis and treatment by polymerizing or enveloping drugs and binding a tissue-specific binder ingredient, but also used for separating a target substance using magnetism, and a process for preparing the same.

The invention relates to pharmaceutical preparations that are used in a method for treating opiate addiction or opiate dependence, especially heroin dependence. The active substance used is preferably diamorphine and / or one of the pharmaceutically acceptable acid addition salts thereof. The invention also relates to a method for treating opiate dependence.

The invention discloses a one-way moisture-transfer all-cotton spunlaced nonwoven and as well as a product and a preparation method thereof. The all-cotton spunlaced nonwoven comprises an all-cotton spunlaced nonwoven matrix, the all-cotton spunlaced nonwoven matrix comprises a hydrophobic surface and a hydrophilic surface, wherein the hydrophobic surface contains hydrophobic substances used for transferring moisture from the hydrophobic surface to the hydrophilic surface. The one-way moisture-transfer all-cotton spunlaced nonwoven selects an all-cotton material, has light and soft texture and good one-way moisture-transfer effect and can effectively absorb and permeate the moisture and prevent the moisture from reversely flowing, thereby enabling the hydrophobic surface directly contacting with the skin of a human body to keep dry and bringing about more comfortable feeling for a user of a one-way moisture-transfer product.

The invention provides a lithium ion battery adopting graphene as a cathode material. The lithium ion battery which is prepared by the low-temperature method and adopts the graphene material as the cathode material includes a metal casing, a plate electrode, electrolytic solution and a septum, wherein active substances used by the anode plate electrode are commonly used anode materials for the lithium ion battery and include lithium cobaltate, lithium iron phosphate, lithium manganate, lithium nickelate, a ternary lithium-nickelate-cobaltate-manganate material and the like; and the electrolytic solution is lithium hexaflourophosphate electrolytic solution used by the lithium ion battery. The cathode of the lithium ion battery adopting the graphene material as the cathode material is made of the graphene material. The first discharge capacity of the lithium ion battery adopting the graphene material as the cathode material can reach 400 to 800mAh / g, and the first charge discharge efficiency can reach 40 to 90 percent; and after 20 cycles, the discharge capacity of the lithium ion battery can still reach 380 to 450mAh / g. The lithium ion battery has the advantages of simple preparation process of the graphene material, easy operation and low cost; and the lithium ion battery adopting the graphene as the cathode material has high discharge capacity and favorable cycle performance.

The invention relates to a halogen-free flame retardant, which is prepared by compounding an organic phosphoric acid compound with polyhydric alcohol according to the mass ratio of (1:10)-(10:1). A halogen-free flame-retardant polyolefin composition comprising the halogen-free flame retardant is prepared from 60-90 parts by weight of polyolefin resin, 10-40 parts by weight of halogen-free flame retardant and 0.05-2 parts by weight of antioxygen. The halogen-free flame-retardant polyolefin composition disclosed by the invention is used for preparing panel, fibre, film or foam materials. According to the invention, the traditional inorganic phosphoric acid substances are replaced by four micromolecular organic phosphoric acid substances used as the acid source and air source components of a halogen-free expansion flame-retardant system; organic phosphate is easier to carry out esterification reaction with polyhydric alcohol in the reaction process; due to the reaction extrusion blending manner, all fire retardant components and matrix resin are ensured to be dispersed uniformly; the blending efficiency is high; the pre-reaction phenomenon caused by long-time staying of materials in a screw can be prevented, thus being beneficial to improving the use efficiency of the flame retardant.

Disclosed is a method for continuously and stably producing a CNT assembly having a high specific surface area in a catalyst activating substance-containing, high-carbon-concentration environment.Specifically disclosed is a method for growing a carbon nanotube by contacting a feedstock gas and a catalyst-activating substance to a catalyst on a base. The method includes: a formation step of supplying and contacting a reducing gas to the catalyst on the base, and heating at least one of the catalyst and the reducing gas to reduce the catalyst and / or particulate the catalyst; and a carbon nanotube growing step of contacting a carbon-containing, oxygen-free feedstock gas and an oxygen-containing catalyst-activating substance to at least one of the catalyst and the catalyst particles, and heating at least one of the catalyst, the catalyst particles, the feedstock gas, and the catalyst-activating substance to grow the carbon nanotube, wherein the ratio of the number concentration of the carbon atoms contained in the feedstock gas used in the carbon nanotube growing step to the number concentration of the oxygen atoms contained in the catalyst-activating substance used in the carbon nanotube growing step ranges from 0.5 to 200.

Methods of improving the appearance of keratinous substances using at least one DHEA derivative such as the skin, hair, eyelashes and / or nails, in particular for preventing or treating cutaneous signs of ageing and / or a faded complexion and / or disorders of pigmentation of the skin or hair and / or drying of the skin and / or hyperseborrhoea and / or imperfections relating to hyperseborrhoea and / or sensitive skin and / or dandruff and / or hair loss and / or canities.

A spectroscopic detector for identifying the presence of a first substance in the presence of another substance includes a laser for illuminating the substances at a plurality of wavelengths to induce the emission of radiation characteristic of the substance; a spectrometer for measuring the emitted radiation to obtain a plurality of spectral measurement data; and a processor for processing the data. An algorithm combines the data into a composite spectrum and a parameter characteristic of the first substance is identified while information in the composite spectrum contributed by emission of radiation from the other substance is removed to identify the presence of the first substance and obtain a characteristic spectral signature of the first substance. The signature is compared to signatures in a spectral library database, wherein at least some of the library signatures have spectral characteristics differentiated from each other by identifiable spectral characteristics caused by environmental factors.

The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and / or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplement formulation to optimize specific health outcomes. Specific to this invention the utilization of certain known polymorphic genes associated with Substance Use Disorder (SUD) are analyzed to target certain genetic anomalies that lead to a high risk and predisposition to SUD. The genotypic patterns are then utilized to provide certain nutritional customized solutions especially related to the attenuation of aberrant abuse of physician prescribed narcotic pain medication across all pain conditions. A priority GENOPROFILE is measured and directs the customization of a subsequent nutraceutical to act as a therapeutic modality. Specifically the treatment includes slow attenuation of the pain medication by incorporating orals (shakes, liquid beverages, pills, tablets, troche, ointments etc.), Intramuscular, Intravenous, intra-rectal and any form necessary to deliver a sufficient amount of an anti-craving and anti-stress nutraceutical. Moreover, the invention includes examples of novel analgesic ointments coupling Synaptamine and such analgesic and other anesthetic compounds including but not limited to Gabapentin, Ketamine, Baclofen, Ketoprofen, Amitriptyline, Lidocaine, Cyclobenzapine, Diclofenac, Menthol, Camphor and Capsaicin. The GENOPROFILE will be used to determine pain sensitivity Intolerance.

The invention discloses a self-lifting water quality purification device applicable to still water lakes. The device comprises a floating island basal body, an air pump, an ecological purification box, floating troughs, an air delivery pipe and an aeration device, wherein the floating island basal body floats on the water surface and aquatic plants are planted on the floating island basal body; the ecological purification box is in a water permeable structure, and substances used for microbial degradation and physical filtration and adsorption are arranged in the ecological purification box; the ecological purification box slides up and down along the air delivery pipe; and the aeration device is arranged below limit switches, is connected with the lower end of the air delivery pipe and is used for delivering oxygen to lake water and the floating troughs. The device has the beneficial effects that integration of plant absorption, microbial degradation, physical filtration and adsorption and oxygenic aeration of the lake water is achieved via the aquatic plants, the ecological purification box and the aeration device; the invention aims to solve the problem that common floating beds have poor still water bottom layer purification efficiency; and three-dimensional purification of the still water is achieved by the self-lifting purification device to gain better water quality purification effects.

A method for preparing a liquid comestible from a cell by passing liquid through the substance using centrifugal forces, wherein gas contained in the cell is controllably purged from the cell as liquid fills the cell. In one embodiment, the method includes prewetting the substance in the cell by filling liquid in the cell and rotating the cell at a first rotational speed; and then extracting the liquid comestible from the cell in an extraction phase which comprises continuing to fill liquid into the cell and rotating the cell at a second rotational speed that is higher than the first rotational speed. The invention also discloses a cell for use in these methods which cell includes a filter for preventing solids from being carried by gas during the gas purge.

To provide chromatographic packings whereby biological components, etc. which cannot be separated by either ion-exchange chromatography or reversed phase chromatography employed alone can be efficiently separated without deteriorating their activities. Use is made of a packing which contains a charged copolymer and makes it possible to change the effective charge density on the surface of a stationary phase by a physical stimulus while fixing a mobile phase to an aqueous system.

A micro structure for sensing a substance using light scattering includes a substrate, a first layer on the substrate, wherein the first layer comprises a metallic material, a second layer over the first layer, and a mask layer over the second layer. A plurality of nano holes are formed through the mask layer and the second layer, wherein the plurality of holes are defined in part by internal surfaces on the second layer and the mask layer. Two or more structure layers are formed on the mask layer and the internal surfaces in the plurality of holes. The two or more structure layers comprise different material compositions.

The present invention describes a method for producing a target substance by utilizing a microorganism comprising culturing the microorganism in a medium, allowing the target substance to accumulate, and collecting the target substance from the medium. Also the microorganism used in the present invention is a mutant strain whereby maltose assimilation is controlled by the interaction between IIAGlc protein of glucose PTS and MalK.

A medical device comprising a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating containing the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. Drugs that are suitable for use in this invention include, but are not limited to,This drug can be used in combination with another drug including those selected from anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these drugs.

There is provided a fluorescent material coating apparatus for a fluorescent lamp. The fluorescent material coating apparatus includes a cassette on which a plurality of glass tubes are detachably mounted, a delivery member having a delivery chamber communicating with first ends of the glass tubes, a negative pressure generating unit for allowing fluorescent solution to be drawn into the glass tubes by generating a negative pressure in the glass tubes communicating with the delivery chamber by lowering the pressure of the delivery chamber, a dry air supplying unit for supplying dry air to the delivery chamber to dry the fluorescent solution applied on inner surfaces of the glass tubes, a solution tank containing the fluorescent solution and disposed below the glass tubes mounted on the cassette, and a moving unit for allowing lower end portions of the glass tubes mounted in the delivery chamber to be dipped into the fluorescent solution contained in the solution tank.

The invention provides a diaphragm for a battery, comprising a base material. The base material comprises through holes, wherein the base material contains polyimide and additives, and the additives are inorganic crystal whiskers and / or orthosilicate ester. The diaphragm prepared by the invention has excellent high-temperature performance, the heat shrinking property of the diaphragm is below 1.1 percent below 400 DEG C, and no cracking phenomenon occurs below 400 DEG C. The mechanical property of the diaphragm is excellent, the tensile-strength of the diaphragm is above 100 Mpa, while the tensile-strength of the diaphragm prepared by the prior art is only 90 Mpa. In addition, perforating substances used by the invention can effectively adjust the average diameter of a hole of the diaphragm within a better range of between 10 and 100 nanometers, thereby guaranteeing the smooth passing of lithium irons in the battery using the diaphragm, reducing the internal resistance of the battery, and having no short circuit.