515 results about "Substance use" patented technology

An apparatus is provided for use in conjunction with a drug delivered to a gastrointestinal (GI) tract of a subject. The apparatus includes an ingestible capsule, which includes one or more electrodes, and a control component, adapted to drive the electrodes to apply an electrical current that induces local delivery of the drug in target tissue of the GI tract. Additional embodiments are also described.

The invention encompasses a method of conducting a clinical trial of a test substance from a primary site, via the internet. The internet is used in various phases of a clinical trial, including: recruiting and screening for candidates who are eligible to participate in a clinical trial of a test substance using the internet; obtaining, directly from a participant at a remote site, personal information as well as information allowing a determination of any effect(s) of the test substance on the participant after use (e.g., by evaluation forms completed and transmitted over the internet); compiling data from multiple participants.

The present disclosure relates to novel dosage forms, drug delivery regimens, methods and pharmaceutical compositions which optimize the therapeutic effects of active therapeutic substances through the application of the concept of uneven dosing.

To provide An electrode for a dielectrophoretic apparatus in which a background detected by reflecting an excited light on an electrode present under the substance (molecule) is reduced and an S/N ratio is enhanced. Also, there is provided an dielectrophoretic apparatus, in an apparatus in which a liquid containing substances to be separated is present in a non-uniform electric field formed by a dielectrophoretic electrode, and separation is carried out by a dielectrophoretic force exerting on the substances, wherein the collecting ability of substances is enhanced. The present invention is characterized in that a vacant space is provided in an electrode whereby substances subjected to influence by a negative dielectrophoretic force can be concentrated in said vacant space of an electrode, or above or below portion of the space.

The invention relates the multicomponent mixed working substance used for preparing dual-temperature by single-machine vapor compression refrigerator. The low temperature is between -60- -40Deg.C and the high temperature is between -25- 10Deg.C. The multicomponent mixed working substance comprises lower boiling working substance and high boiling working substance. The lower boiling working substance comprises tetrafluoromethane, ethylene, ethane, fluoroethylene, trifluoromethane, fluoromethane, hydrofluoeic ether, carbon dioxide, difluoromethane and penfluoroethane; the high boiling working substance comprises trifluoro-thane, hydrofluoeic ether, propylene, propane, perfluoropropylamine, propadiene, cyclopropane, difluo-monochloromethane, penta-monochloroethane, perfluoroethane, difluoroethane, isobutene, butane, butylenes, isobutylene, sevofluoropropane, hexafluoropropane, penfluoropropane and tetrachloromonofluoroethane.

A capsule designed for insertion in a centrifugal beverage production device for preparing a beverage from a substance contained in the capsule by introducing liquid in the capsule and passing liquid through the substance using centrifugal forces. The capsule has a body with bottom and open ends that are spaced apart in the axial direction, an upper wall for covering the body at its open end along a direction transverse to the axial direction, and an enclosure between the body and upper wall containing a predetermined amount of beverage substance. The capsule also includes an annular pressure-setting ring configured for adjusting the backpressure in the beverage production device. The pressure-setting ring provides improved quality of in-cup coffee. Also, a set of capsules having pressure-setting rings of different dimensions is provided for setting different backpressure when the capsules are engaged in a centrifuging beverage production device.

The invention provides a sodium ion secondary battery, and a layered manganese-containing oxide active substance and an anode active substance used in the sodium ion secondary battery; the chemical general formula of the anode active substance is Na[x]A[y]Mn[1-y]O[2], wherein A is one or more selected from a group including Li, Mg, Cu, Zn, Al, V and Fe; x is more than 0.4 and less than 0.9, y is more than 0.05 and less than 0.5, delta is more than minus 0.1 and less than 0.1. Average working voltage of the anode active substance of the sodium ion secondary battery disclosed by the invention in the sodium ion secondary battery is 2.6-3.8V; furthermore, a novel anode material of layered doped manganese oxide disclosed by the invention is good in safety performance, low in cost and good in cycling stability.

A process for electrolyzing an aqueous solution of hydrochloric acid to chlorine in an electrochemical cell provided with an anode compartment and a cathode compartment including at least one gas diffusion cathode comprising an electrically conductive web provided on at least one side thereof with a coating of a catalyst for the electroreduction of oxygen comprising rhodium sulfide and optionally containing at least one fluorinated binder incorporated therein, comprising introducing aqueous hydrochloric acid containing contaminant species into the anode compartment and oxygen into the cathode compartment while impressing a direct electric current on the cell.

The present invention relates to water soluble magnetic nanocomposite using an amphiphilic compound. Specifically, the present invention relates to water soluble magnetic nanocomposite which may be not only used as a contrast agent for magnetic resonance imaging (MRI), an intelligent contrast agent for diagnosing cancer characterized by binding a tissue-specific binder ingredient, a drug delivery system for simultaneous diagnosis and treatment by polymerizing or enveloping drugs and binding a tissue-specific binder ingredient, but also used for separating a target substance using magnetism, and a process for preparing the same.

The invention discloses a one-way moisture-transfer all-cotton spunlaced nonwoven and as well as a product and a preparation method thereof. The all-cotton spunlaced nonwoven comprises an all-cotton spunlaced nonwoven matrix, the all-cotton spunlaced nonwoven matrix comprises a hydrophobic surface and a hydrophilic surface, wherein the hydrophobic surface contains hydrophobic substances used for transferring moisture from the hydrophobic surface to the hydrophilic surface. The one-way moisture-transfer all-cotton spunlaced nonwoven selects an all-cotton material, has light and soft texture and good one-way moisture-transfer effect and can effectively absorb and permeate the moisture and prevent the moisture from reversely flowing, thereby enabling the hydrophobic surface directly contacting with the skin of a human body to keep dry and bringing about more comfortable feeling for a user of a one-way moisture-transfer product.

A method and apparatus are provided for identifying molecular structures within a sample substance using an integrated circuit array sensor having a plurality of test sites upon which the sample substance is applied. Each test site includes a probe formed therein to bond with an associated target molecular structure. An electrical signal produced on the test site upon forming or breaking of molecular probe-target duplexes is detected to determine which probes have bonded to an associated target molecular structure.

The invention relates to a halogen-free flame retardant, which is prepared by compounding an organic phosphoric acid compound with polyhydric alcohol according to the mass ratio of (1:10)-(10:1). A halogen-free flame-retardant polyolefin composition comprising the halogen-free flame retardant is prepared from 60-90 parts by weight of polyolefin resin, 10-40 parts by weight of halogen-free flame retardant and 0.05-2 parts by weight of antioxygen. The halogen-free flame-retardant polyolefin composition disclosed by the invention is used for preparing panel, fibre, film or foam materials. According to the invention, the traditional inorganic phosphoric acid substances are replaced by four micromolecular organic phosphoric acid substances used as the acid source and air source components of a halogen-free expansion flame-retardant system; organic phosphate is easier to carry out esterification reaction with polyhydric alcohol in the reaction process; due to the reaction extrusion blending manner, all fire retardant components and matrix resin are ensured to be dispersed uniformly; the blending efficiency is high; the pre-reaction phenomenon caused by long-time staying of materials in a screw can be prevented, thus being beneficial to improving the use efficiency of the flame retardant.

Disclosed is a method for continuously and stably producing a CNT assembly having a high specific surface area in a catalyst activating substance-containing, high-carbon-concentration environment.

Specifically disclosed is a method for growing a carbon nanotube by contacting a feedstock gas and a catalyst-activating substance to a catalyst on a base. The method includes: a formation step of supplying and contacting a reducing gas to the catalyst on the base, and heating at least one of the catalyst and the reducing gas to reduce the catalyst and/or particulate the catalyst; and a carbon nanotube growing step of contacting a carbon-containing, oxygen-free feedstock gas and an oxygen-containing catalyst-activating substance to at least one of the catalyst and the catalyst particles, and heating at least one of the catalyst, the catalyst particles, the feedstock gas, and the catalyst-activating substance to grow the carbon nanotube, wherein the ratio of the number concentration of the carbon atoms contained in the feedstock gas used in the carbon nanotube growing step to the number concentration of the oxygen atoms contained in the catalyst-activating substance used in the carbon nanotube growing step ranges from 0.5 to 200.

Methods of improving the appearance of keratinous substances using at least one DHEA derivative such as the skin, hair, eyelashes and/or nails, in particular for preventing or treating cutaneous signs of ageing and/or a faded complexion and/or disorders of pigmentation of the skin or hair and/or drying of the skin and/or hyperseborrhoea and/or imperfections relating to hyperseborrhoea and/or sensitive skin and/or dandruff and/or hair loss and/or canities.

A spectroscopic detector for identifying the presence of a first substance in the presence of another substance includes a laser for illuminating the substances at a plurality of wavelengths to induce the emission of radiation characteristic of the substance; a spectrometer for measuring the emitted radiation to obtain a plurality of spectral measurement data; and a processor for processing the data. An algorithm combines the data into a composite spectrum and a parameter characteristic of the first substance is identified while information in the composite spectrum contributed by emission of radiation from the other substance is removed to identify the presence of the first substance and obtain a characteristic spectral signature of the first substance. The signature is compared to signatures in a spectral library database, wherein at least some of the library signatures have spectral characteristics differentiated from each other by identifiable spectral characteristics caused by environmental factors.

The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and/or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplement formulation to optimize specific health outcomes. Specific to this invention the utilization of certain known polymorphic genes associated with Substance Use Disorder (SUD) are analyzed to target certain genetic anomalies that lead to a high risk and predisposition to SUD. The genotypic patterns are then utilized to provide certain nutritional customized solutions especially related to the attenuation of aberrant abuse of physician prescribed narcotic pain medication across all pain conditions. A priority GENOPROFILE is measured and directs the customization of a subsequent nutraceutical to act as a therapeutic modality. Specifically the treatment includes slow attenuation of the pain medication by incorporating orals (shakes, liquid beverages, pills, tablets, troche, ointments etc.), Intramuscular, Intravenous, intra-rectal and any form necessary to deliver a sufficient amount of an anti-craving and anti-stress nutraceutical. Moreover, the invention includes examples of novel analgesic ointments coupling Synaptamine and such analgesic and other anesthetic compounds including but not limited to Gabapentin, Ketamine, Baclofen, Ketoprofen, Amitriptyline, Lidocaine, Cyclobenzapine, Diclofenac, Menthol, Camphor and Capsaicin. The GENOPROFILE will be used to determine pain sensitivity Intolerance.

The invention discloses a self-lifting water quality purification device applicable to still water lakes. The device comprises a floating island basal body, an air pump, an ecological purification box, floating troughs, an air delivery pipe and an aeration device, wherein the floating island basal body floats on the water surface and aquatic plants are planted on the floating island basal body; the ecological purification box is in a water permeable structure, and substances used for microbial degradation and physical filtration and adsorption are arranged in the ecological purification box; the ecological purification box slides up and down along the air delivery pipe; and the aeration device is arranged below limit switches, is connected with the lower end of the air delivery pipe and is used for delivering oxygen to lake water and the floating troughs. The device has the beneficial effects that integration of plant absorption, microbial degradation, physical filtration and adsorption and oxygenic aeration of the lake water is achieved via the aquatic plants, the ecological purification box and the aeration device; the invention aims to solve the problem that common floating beds have poor still water bottom layer purification efficiency; and three-dimensional purification of the still water is achieved by the self-lifting purification device to gain better water quality purification effects.

A method for preparing a liquid comestible from a cell by passing liquid through the substance using centrifugal forces, wherein gas contained in the cell is controllably purged from the cell as liquid fills the cell. In one embodiment, the method includes prewetting the substance in the cell by filling liquid in the cell and rotating the cell at a first rotational speed; and then extracting the liquid comestible from the cell in an extraction phase which comprises continuing to fill liquid into the cell and rotating the cell at a second rotational speed that is higher than the first rotational speed. The invention also discloses a cell for use in these methods which cell includes a filter for preventing solids from being carried by gas during the gas purge.

To provide chromatographic packings whereby biological components, etc. which cannot be separated by either ion-exchange chromatography or reversed phase chromatography employed alone can be efficiently separated without deteriorating their activities. Use is made of a packing which contains a charged copolymer and makes it possible to change the effective charge density on the surface of a stationary phase by a physical stimulus while fixing a mobile phase to an aqueous system.

A micro structure for sensing a substance using light scattering includes a substrate, a first layer on the substrate, wherein the first layer comprises a metallic material, a second layer over the first layer, and a mask layer over the second layer. A plurality of nano holes are formed through the mask layer and the second layer, wherein the plurality of holes are defined in part by internal surfaces on the second layer and the mask layer. Two or more structure layers are formed on the mask layer and the internal surfaces in the plurality of holes. The two or more structure layers comprise different material compositions.

There is provided a fluorescent material coating apparatus for a fluorescent lamp. The fluorescent material coating apparatus includes a cassette on which a plurality of glass tubes are detachably mounted, a delivery member having a delivery chamber communicating with first ends of the glass tubes, a negative pressure generating unit for allowing fluorescent solution to be drawn into the glass tubes by generating a negative pressure in the glass tubes communicating with the delivery chamber by lowering the pressure of the delivery chamber, a dry air supplying unit for supplying dry air to the delivery chamber to dry the fluorescent solution applied on inner surfaces of the glass tubes, a solution tank containing the fluorescent solution and disposed below the glass tubes mounted on the cassette, and a moving unit for allowing lower end portions of the glass tubes mounted in the delivery chamber to be dipped into the fluorescent solution contained in the solution tank.

The invention provides a diaphragm for a battery, comprising a base material. The base material comprises through holes, wherein the base material contains polyimide and additives, and the additives are inorganic crystal whiskers and/or orthosilicate ester. The diaphragm prepared by the invention has excellent high-temperature performance, the heat shrinking property of the diaphragm is below 1.1 percent below 400 DEG C, and no cracking phenomenon occurs below 400 DEG C. The mechanical property of the diaphragm is excellent, the tensile-strength of the diaphragm is above 100 Mpa, while the tensile-strength of the diaphragm prepared by the prior art is only 90 Mpa. In addition, perforating substances used by the invention can effectively adjust the average diameter of a hole of the diaphragm within a better range of between 10 and 100 nanometers, thereby guaranteeing the smooth passing of lithium irons in the battery using the diaphragm, reducing the internal resistance of the battery, and having no short circuit.