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2 results about "Melanocortin" patented technology
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The melanocortins are a group of peptide hormones which include adrenocorticotropic hormone (ACTH) and the different forms of melanocyte-stimulating hormone (MSH), and are derived from proopiomelanocortin (POMC) in the pituitary gland. The melanocortins exert their effects by binding to and activating the melanocortin receptors.
Combinations of a potassium channel activator and an mc4r agonist and related methods of use
The description refers to a method for treating a disease or disorder in a subject by using a combination of: (i) a potassium channel activator (e.g., a SURx / Kirx channel activating compound) or a pharmaceutically acceptable salt thereof; and (ii) a melanocortin-4 receptor (MC4R) agonist.
Owner:RHYTHM PHARMACEUTICALS INC
Use of melanocortin-4 receptor agonists for the treatment of a LEPR and / or SH2b1 deficiency
The present disclosure relates to the use of a compound of chemical Formula 1 or a pharmaceutically acceptable salt thereof for the purpose of preventing, improving, or treating a genetic obesity disease associated with the melanocortin-4 receptor (MC4R) pathway, particularly a genetic obesity disease associated with SH2B1 deficiency or a LEPR deficiency.
Owner:LG CHEM LTD +3