4 results about "Male erectile dysfunction" patented technology

The application belongs to the field of regenerative medicine and nano drug delivery system, and particularly relates to a drug-loaded exosome for improving the testosterone secretion capacity of testicular interstitial cells and a preparation method and application thereof. The application links a targeting FATE1 polypeptide to the surface of MSC-derived exosomes by a chemical coupling method, and loads a small molecule compound in the exosomes by electroporation, so as to obtain modified MSC-derived exosomes. The obtained exosomes can obtain the targeting capacity in testicular interstitial cells, and the natural repair capacity of MSC-derived exosomes and the release of small molecule drugs promote the repair of damaged cells, improve the testosterone secretion capacity of testicular interstitial cells, and relieve male erectile dysfunction caused by diseases or aging.

The present application relates to the technical field of medical devices, in particular to a kind of external device for treating male erectile dysfunction, including outer tube, and the negative pressure pump and internal inner tube of the internal inside being arranged at the front end of outer tube,It also includes ball hinge seat, movably connected at the rear end of outer tube, and there is silica gel sealing ring at the opening of its rear end;Control center, installed at the front end inside outer tube, and installed at the output end of negative pressure pump, control center is connected with temperature control sensing device, temperature control sensing device is installed on the I-shaped connecting seat at the rear end of inner tube, solve the single negative pressure control mode of existing device, manually cannot be accurate control pressure and cause tissue damage or affect erection effect, the pressure program of automatic version is fixed, complex structure, poor portability, and cannot be adapted to the angle change after penis erection, easily cause compression pain, air leakage pressure loss;Lack of auxiliary physical stimulation, limited efficacy;In addition, local hypothermia under negative pressure causes body discomfort, also can contract blood vessels, hinder blood perfusion and erection maintenance problem.

The application belongs to the field of traditional Chinese medicine, and particularly relates to a time-delay spray containing dry toad extract and toad oil and a preparation method thereof. The time-delay spray provided by the application can significantly treat male erectile dysfunction. The time-delay spray prepared by the application has the advantages of direct action, quantitative drug delivery, and no contact to avoid drug pollution. The application realizes the transformation of waste into treasure of toad oil, fully excavates the medicinal value of toad oil, further improves the rational utilization system of toad resources, and provides a practical scheme for efficient development of toad medicinal resources.